JP2014532660A - 電位作動型ナトリウムチャネルにおける選択活性を有するベンゾオキサゾリノン化合物 - Google Patents
電位作動型ナトリウムチャネルにおける選択活性を有するベンゾオキサゾリノン化合物 Download PDFInfo
- Publication number
- JP2014532660A JP2014532660A JP2014539066A JP2014539066A JP2014532660A JP 2014532660 A JP2014532660 A JP 2014532660A JP 2014539066 A JP2014539066 A JP 2014539066A JP 2014539066 A JP2014539066 A JP 2014539066A JP 2014532660 A JP2014532660 A JP 2014532660A
- Authority
- JP
- Japan
- Prior art keywords
- oxo
- sulfonamide
- dihydro
- benzoxazole
- thiadiazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 C1NC*OC1 Chemical compound C1NC*OC1 0.000 description 6
- CVQRJRLLLGCIMO-UHFFFAOYSA-N CC(C)(C)OC(Nc1ccc(CCCC2=O)c2c1)=O Chemical compound CC(C)(C)OC(Nc1ccc(CCCC2=O)c2c1)=O CVQRJRLLLGCIMO-UHFFFAOYSA-N 0.000 description 1
- MGGOEMYITVNPPA-UHFFFAOYSA-N CC(C)(C)OC(Nc1ccc(CCCC2O)c2c1)=O Chemical compound CC(C)(C)OC(Nc1ccc(CCCC2O)c2c1)=O MGGOEMYITVNPPA-UHFFFAOYSA-N 0.000 description 1
- QOIVUVHNIYWPRK-UHFFFAOYSA-N Nc1cc(C(CCC2)N(c(c(O3)c4)ccc4S(Nc4ncn[s]4)(=O)=O)C3=O)c2cc1 Chemical compound Nc1cc(C(CCC2)N(c(c(O3)c4)ccc4S(Nc4ncn[s]4)(=O)=O)C3=O)c2cc1 QOIVUVHNIYWPRK-UHFFFAOYSA-N 0.000 description 1
- IDNLVJHOEZJNHW-UHFFFAOYSA-N Nc1ccc(CCCC2=O)c2c1 Chemical compound Nc1ccc(CCCC2=O)c2c1 IDNLVJHOEZJNHW-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161552885P | 2011-10-28 | 2011-10-28 | |
| US61/552,885 | 2011-10-28 | ||
| PCT/US2012/062207 WO2013063459A1 (en) | 2011-10-28 | 2012-10-26 | Benzoxazolinone compounds with selective activity in voltage-gated sodium channels |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014532660A true JP2014532660A (ja) | 2014-12-08 |
| JP2014532660A5 JP2014532660A5 (enExample) | 2015-12-10 |
Family
ID=48168585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014539066A Pending JP2014532660A (ja) | 2011-10-28 | 2012-10-26 | 電位作動型ナトリウムチャネルにおける選択活性を有するベンゾオキサゾリノン化合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9273040B2 (enExample) |
| EP (1) | EP2770995B1 (enExample) |
| JP (1) | JP2014532660A (enExample) |
| KR (1) | KR20140095067A (enExample) |
| CN (1) | CN103889419A (enExample) |
| AU (1) | AU2012328561A1 (enExample) |
| BR (1) | BR112014010197A2 (enExample) |
| CA (1) | CA2852796A1 (enExample) |
| IN (1) | IN2014CN02959A (enExample) |
| MX (1) | MX2014005068A (enExample) |
| RU (1) | RU2014121489A (enExample) |
| WO (1) | WO2013063459A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20170134443A (ko) * | 2015-03-02 | 2017-12-06 | 암젠 인크 | 비시클릭 케톤 술폰아마이드 화합물 |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9630929B2 (en) | 2011-10-31 | 2017-04-25 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| RU2014121983A (ru) | 2011-10-31 | 2015-12-10 | Ксенон Фармасьютикалз Инк. | Биарильные простоэфирные сульфонамиды и их применение в качестве терапевтических средств |
| US8952169B2 (en) | 2012-05-22 | 2015-02-10 | Xenon Pharmaceuticals Inc. | N-substituted benzamides and methods of use thereof |
| CN104797555B (zh) | 2012-07-06 | 2017-12-22 | 基因泰克公司 | N‑取代的苯甲酰胺及其使用方法 |
| HK1213476A1 (zh) | 2013-03-14 | 2016-07-08 | 基因泰克公司 | 取代的三唑並吡啶及其使用方法 |
| CA2898680A1 (en) | 2013-03-15 | 2014-09-18 | Genentech,Inc. | Substituted benzoxazoles and methods of use thereof |
| CA2931732A1 (en) | 2013-11-27 | 2015-06-04 | Genentech, Inc. | Substituted benzamides and methods of use thereof |
| EP3126360A1 (en) | 2014-03-29 | 2017-02-08 | Lupin Limited | Sulfonamide compounds as voltage gated sodium channel modulators |
| WO2016007534A1 (en) | 2014-07-07 | 2016-01-14 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
| PE20180575A1 (es) | 2015-05-22 | 2018-04-04 | Genentech Inc | Benzamidas sustituidas y metodos para utilizarlas |
| MA42683A (fr) | 2015-08-27 | 2018-07-04 | Genentech Inc | Composés thérapeutiques et leurs méthodes utilisation |
| BR112018006189A2 (pt) | 2015-09-28 | 2018-10-09 | Genentech Inc | compostos da fórmula, composição farmacêutica, métodos de tratamento de uma doença, de diminuição do fluxo de íons e de tratamento de prurido em um mamífero, método para tratamento de dores em um mamífero e uso de um composto |
| JP2018535234A (ja) | 2015-11-25 | 2018-11-29 | ジェネンテック， インコーポレイテッド | ナトリウムチャネル遮断薬として有用な置換ベンズアミド |
| EP3390374B1 (en) | 2015-12-18 | 2020-08-26 | Merck Sharp & Dohme Corp. | Hydroxyalkylamine- and hydroxycycloalkylamine-substituted diamine-arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
| CN109071426A (zh) | 2016-03-30 | 2018-12-21 | 基因泰克公司 | 取代的苯甲酰胺及其使用方法 |
| CA3023465C (en) | 2016-05-20 | 2024-09-24 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| WO2018072602A1 (en) | 2016-10-17 | 2018-04-26 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
| AU2017371674B2 (en) | 2016-12-09 | 2021-07-22 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| JP2020511511A (ja) | 2017-03-24 | 2020-04-16 | ジェネンテック， インコーポレイテッド | ナトリウムチャネル阻害剤としての４−ピペリジン−ｎ−（ピリミジン−４−イル）クロマン−７−スルホンアミド誘導体 |
| UY37729A (es) * | 2017-05-11 | 2019-01-02 | Glaxosmithkline Ip Dev Ltd | NUEVOS COMPUESTOS QUE INHIBEN LA ACTIVIDAD DE Nav1.7 |
| EP3759098A1 (en) | 2018-02-26 | 2021-01-06 | Genentech, Inc. | Pyridine-sulfonamide compounds and their use against pain and related conditions |
| US10947251B2 (en) | 2018-03-30 | 2021-03-16 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
| US11512072B2 (en) | 2018-04-19 | 2022-11-29 | University Of Virginia Patent Foundation | Compositions and methods for preparing and using azetidines |
| TW202003490A (zh) | 2018-05-22 | 2020-01-16 | 瑞士商赫孚孟拉羅股份公司 | 治療性化合物及其使用方法 |
| CN112262142B (zh) | 2018-06-13 | 2023-11-14 | 泽农医药公司 | 苯磺酰胺化合物及其作为治疗剂的用途 |
| MA53489A (fr) | 2018-08-31 | 2021-12-08 | Xenon Pharmaceuticals Inc | Composés de sulfonamide substitués par hétéroaryle et leur utilisation en tant qu'agents thérapeutiques |
| US10752623B2 (en) | 2018-08-31 | 2020-08-25 | Xenon Pharmaceuticals Inc. | Heteroaryl-substituted sulfonamide compounds and their use as sodium channel inhibitors |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008540539A (ja) * | 2005-05-10 | 2008-11-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | イオンチャンネルの調節因子としての二環系誘導体 |
| JP2008543785A (ja) * | 2005-06-09 | 2008-12-04 | バーテックス ファーマシューティカルズ インコーポレイテッド | イオンチャネルの調節因子としてのインダン誘導体 |
| JP2010533652A (ja) * | 2007-07-13 | 2010-10-28 | アイカジェン， インコーポレイテッド | ナトリウムチャネル阻害物質 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09124620A (ja) * | 1995-10-11 | 1997-05-13 | Bristol Myers Squibb Co | 置換ビフェニルスルホンアミドエンドセリン拮抗剤 |
| CN1177831C (zh) * | 1998-12-04 | 2004-12-01 | 神经研究公司 | 作为离子通道调节剂的新的苯并咪唑啉酮一、苯并噁唑酮一或苯并噻唑啉酮衍生物 |
| CZ20032850A3 (cs) * | 2001-04-18 | 2004-02-18 | Euro-Celtique, S. A. | Analogy nociceptinu |
| EP1467986A1 (en) * | 2002-01-17 | 2004-10-20 | Eli Lilly And Company | Aza-cyclic compounds as modulators of acetylcholine receptors |
| CA2633653A1 (en) * | 2005-12-21 | 2007-07-05 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives as modulators of ion channels |
| CA2734651A1 (en) * | 2008-08-21 | 2010-02-25 | Richter Gedeon Nyrt. | Methods for treating neuropathic pain |
| GEP20135992B (en) | 2009-01-12 | 2013-12-25 | Icagen Inc | Sulfonamide derivatives |
| PL2427441T3 (pl) * | 2009-05-04 | 2017-06-30 | Agios Pharmaceuticals, Inc. | Aktywatory PKM2 do stosowania w leczeniu raka |
-
2012
- 2012-10-26 KR KR1020147013911A patent/KR20140095067A/ko not_active Withdrawn
- 2012-10-26 US US14/353,488 patent/US9273040B2/en active Active
- 2012-10-26 WO PCT/US2012/062207 patent/WO2013063459A1/en not_active Ceased
- 2012-10-26 JP JP2014539066A patent/JP2014532660A/ja active Pending
- 2012-10-26 BR BR112014010197A patent/BR112014010197A2/pt not_active IP Right Cessation
- 2012-10-26 MX MX2014005068A patent/MX2014005068A/es not_active Application Discontinuation
- 2012-10-26 CA CA2852796A patent/CA2852796A1/en not_active Abandoned
- 2012-10-26 EP EP12843015.4A patent/EP2770995B1/en not_active Not-in-force
- 2012-10-26 IN IN2959CHN2014 patent/IN2014CN02959A/en unknown
- 2012-10-26 RU RU2014121489/04A patent/RU2014121489A/ru not_active Application Discontinuation
- 2012-10-26 CN CN201280052937.2A patent/CN103889419A/zh active Pending
- 2012-10-26 AU AU2012328561A patent/AU2012328561A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008540539A (ja) * | 2005-05-10 | 2008-11-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | イオンチャンネルの調節因子としての二環系誘導体 |
| JP2008543785A (ja) * | 2005-06-09 | 2008-12-04 | バーテックス ファーマシューティカルズ インコーポレイテッド | イオンチャネルの調節因子としてのインダン誘導体 |
| JP2010533652A (ja) * | 2007-07-13 | 2010-10-28 | アイカジェン， インコーポレイテッド | ナトリウムチャネル阻害物質 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20170134443A (ko) * | 2015-03-02 | 2017-12-06 | 암젠 인크 | 비시클릭 케톤 술폰아마이드 화합물 |
| JP2018510858A (ja) * | 2015-03-02 | 2018-04-19 | アムジエン・インコーポレーテツド | 二環式ケトンスルホンアミド化合物 |
| KR102649836B1 (ko) | 2015-03-02 | 2024-03-22 | 암젠 인크 | 비시클릭 케톤 술폰아마이드 화합물 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103889419A (zh) | 2014-06-25 |
| CA2852796A1 (en) | 2013-05-02 |
| EP2770995A1 (en) | 2014-09-03 |
| US20140303143A1 (en) | 2014-10-09 |
| BR112014010197A2 (pt) | 2017-04-18 |
| US9273040B2 (en) | 2016-03-01 |
| RU2014121489A (ru) | 2015-12-10 |
| AU2012328561A1 (en) | 2014-04-17 |
| IN2014CN02959A (enExample) | 2015-07-03 |
| EP2770995A4 (en) | 2015-06-03 |
| KR20140095067A (ko) | 2014-07-31 |
| AU2012328561A8 (en) | 2014-05-01 |
| EP2770995B1 (en) | 2019-01-02 |
| WO2013063459A1 (en) | 2013-05-02 |
| MX2014005068A (es) | 2014-07-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014532660A (ja) | 電位作動型ナトリウムチャネルにおける選択活性を有するベンゾオキサゾリノン化合物 | |
| US9624208B2 (en) | Benzoxazolinone compounds with selective activity in voltage-gated sodium channels | |
| KR102408272B1 (ko) | 베타-3 아드레날린성 수용체와 관련된 장애의 치료 또는 예방에 유용한 베타-3 아드레날린성 수용체의 조정제 | |
| JP6305510B2 (ja) | ヤヌスキナーゼ阻害剤としての非環式シアノエチルピラゾロピリドン | |
| EA025322B1 (ru) | Производные дигидробензооксазина и дигидропиридооксазина | |
| KR20180016485A (ko) | 무스카린성 m2 수용체의 양성 알로스테릭 조정제 | |
| EP4423068B1 (en) | Rxfp1 agonists | |
| KR20250005373A (ko) | 통증 치료를 위한 헤테로아릴 화합물 | |
| TWI726916B (zh) | 治療性化合物及其使用方法 | |
| CN107849047A (zh) | 一种联苯衍生物及其制备方法和在医药上的用途 | |
| CA3233474A1 (en) | Tricyclic gpr65 modulators | |
| US11384097B2 (en) | Tetrahydroisoquinoline derivative, preparation method therefor and use thereof | |
| JP2008504332A (ja) | ドーパミンｄ３受容体に対してアフィニティーを有する化合物およびその医薬における使用 | |
| WO2025133915A1 (en) | Compounds which bind to pnpla3i148m and their use to treat liver diseases | |
| EP2516446B1 (en) | Substituted hexahydrochromeno[3,4-b]pyrroles with affinity for the serotonin receptor (5-ht) family | |
| OA21895A (en) | N-(HydroxyalkyI (Hetero) Aryl) Tetrahydrofuran carboxamides as modulators of sodium channels. | |
| ES2356843T3 (es) | Derivados de triazol como moduladores de los receptores d3 de dopamina. | |
| HK1174918B (en) | Substituted hexahydrochromeno[3,4-b]pyrroles with affinity for the serotonin receptor (5-ht) family |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20151020 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20151020 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20160526 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160607 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20170110 |