JP2014529417A5 - - Google Patents

Download PDF

Info

Publication number
JP2014529417A5
JP2014529417A5 JP2014524040A JP2014524040A JP2014529417A5 JP 2014529417 A5 JP2014529417 A5 JP 2014529417A5 JP 2014524040 A JP2014524040 A JP 2014524040A JP 2014524040 A JP2014524040 A JP 2014524040A JP 2014529417 A5 JP2014529417 A5 JP 2014529417A5
Authority
JP
Japan
Prior art keywords
scaffold
conduits
sensor
fluid
along
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014524040A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014529417A (ja
JP6230996B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2012/049100 external-priority patent/WO2013019830A2/en
Publication of JP2014529417A publication Critical patent/JP2014529417A/ja
Publication of JP2014529417A5 publication Critical patent/JP2014529417A5/ja
Application granted granted Critical
Publication of JP6230996B2 publication Critical patent/JP6230996B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014524040A 2011-08-01 2012-08-01 微小流体薬剤送達装置 Expired - Fee Related JP6230996B2 (ja)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US201161513943P 2011-08-01 2011-08-01
US201161513954P 2011-08-01 2011-08-01
US201161513952P 2011-08-01 2011-08-01
US201161513939P 2011-08-01 2011-08-01
US201161513948P 2011-08-01 2011-08-01
US201161513935P 2011-08-01 2011-08-01
US201161513961P 2011-08-01 2011-08-01
US61/513,961 2011-08-01
US61/513,954 2011-08-01
US61/513,939 2011-08-01
US61/513,948 2011-08-01
US61/513,935 2011-08-01
US61/513,943 2011-08-01
US61/513,952 2011-08-01
US201261615939P 2012-03-27 2012-03-27
US61/615,939 2012-03-27
PCT/US2012/049100 WO2013019830A2 (en) 2011-08-01 2012-08-01 Microfluidic drug delivery devices

Publications (3)

Publication Number Publication Date
JP2014529417A JP2014529417A (ja) 2014-11-13
JP2014529417A5 true JP2014529417A5 (enExample) 2015-09-17
JP6230996B2 JP6230996B2 (ja) 2017-11-15

Family

ID=47627379

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014524040A Expired - Fee Related JP6230996B2 (ja) 2011-08-01 2012-08-01 微小流体薬剤送達装置

Country Status (9)

Country Link
US (4) US10137244B2 (enExample)
EP (2) EP2739341B1 (enExample)
JP (1) JP6230996B2 (enExample)
KR (1) KR102059383B1 (enExample)
CN (1) CN103826690B (enExample)
AU (4) AU2012290129B2 (enExample)
CA (3) CA3125150A1 (enExample)
ES (1) ES2854832T3 (enExample)
WO (1) WO2013019830A2 (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3125150A1 (en) 2011-08-01 2013-02-07 Alcyone Lifesciences, Inc. Microfluidic drug delivery devices
US9919129B2 (en) 2012-12-18 2018-03-20 Alcyone Lifesciences, Inc. Systems and methods for reducing or preventing backflow in a delivery system
WO2014204954A1 (en) 2013-06-17 2014-12-24 Alcyone Lifesciences, Inc. Methods and devices for protecting catheter tips and stereotactic fixtures for microcatheters
ES2738298T3 (es) * 2013-07-31 2020-01-21 Alcyone Lifesciences Inc Sistemas y métodos de suministro de fármacos, tratamiento y monitoreo
KR101562865B1 (ko) * 2014-01-24 2015-10-26 한국과학기술연구원 신경 영양인자를 감지하기 위한 초소형 센서 시스템
US10213564B2 (en) 2014-05-19 2019-02-26 Frank J. Cain Biomedical aural delivery systems and methods
WO2016014464A1 (en) 2014-07-21 2016-01-28 The Cleveland Clinic Foundation Convection enhanced delivery device and system
US9968765B2 (en) 2014-07-21 2018-05-15 The Cleveland Clinic Foundation Convection enhanced delivery device and system
MX2017009336A (es) 2015-01-16 2017-11-15 Voyager Therapeutics Inc Polinucleótidos dirigidos al sistema nervioso central.
US10806396B2 (en) 2015-01-26 2020-10-20 Alcyone Lifesciences, Inc. Drug delivery methods with tracer
US10130740B2 (en) * 2015-03-17 2018-11-20 Wells Johnson Company Pressure control during processing of adipose tissue
US10143811B2 (en) * 2015-03-17 2018-12-04 Wells Johnson Company Fluid management of adipose tissue
WO2016183123A1 (en) 2015-05-11 2016-11-17 Alcyone Lifesciences, Inc. Drug delivery systems and methods
US10286128B2 (en) * 2015-05-22 2019-05-14 Wells Johnson Company Pressure control during processing of adipose tissue
KR102483951B1 (ko) 2015-06-22 2023-01-03 삼성디스플레이 주식회사 액정 표시 장치 및 액정 표시 장치의 제조 방법
US10315016B2 (en) * 2016-01-04 2019-06-11 Corflow Therapeutics Ag System and methods for treating MVO
JP2019502473A (ja) 2016-01-04 2019-01-31 アルキオーネ・ライフサイエンシズ・インコーポレイテッドAlcyone Lifesciences, Inc. 脳卒中を治療するための方法および装置
JP6729026B2 (ja) * 2016-06-15 2020-07-22 ウシオ電機株式会社 マイクロ流路チップおよび検体濃度測定装置
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
CN114887153A (zh) 2016-12-21 2022-08-12 亚克安娜治疗学有限公司 药物递送系统和方法
KR20190098215A (ko) 2016-12-21 2019-08-21 멤젠 엘엘씨 무장된 복제-가능 종양 분해 아데노바이러스
WO2018169955A1 (en) * 2017-03-14 2018-09-20 Massachusetts Institute Of Technology Systems and methods for neural drug delivery and modulation of brain activity
EP3662060A2 (en) 2017-08-03 2020-06-10 Voyager Therapeutics, Inc. Compositions and methods for delivery of aav
CA3076035A1 (en) 2017-09-19 2019-03-28 Corflow Therapeutics Ag Intracoronary characterization of microvascular obstruction (mvo) and myocardial infarction
US10675438B2 (en) * 2017-11-15 2020-06-09 Alcyone Lifesciences, Inc. Therapy specific, pre-programmed auto injection device
EP3761892B1 (en) 2018-03-09 2024-07-24 Corflow Therapeutics AG System for diagnosing and treating microvascular obstructions
US20190314574A1 (en) 2018-04-13 2019-10-17 Alcyone Lifesciences, Inc. Devices and methods for percutaneous lung intratumoral therapy delivery
TW202015742A (zh) 2018-05-15 2020-05-01 美商航海家醫療公司 投遞腺相關病毒(aav)之組成物和方法
MX2020012077A (es) 2018-05-15 2021-03-09 Voyager Therapeutics Inc Composiciones y metodos para el tratamiento de la enfermedad de parkinson.
WO2019222444A2 (en) 2018-05-16 2019-11-21 Voyager Therapeutics, Inc. Directed evolution
EP3793686A1 (en) 2018-05-16 2021-03-24 Voyager Therapeutics, Inc. Aav serotypes for brain specific payload delivery
US12100516B2 (en) 2018-05-31 2024-09-24 Corflow Therapeutics Ag Microfluidic coronary circulatory model
WO2020023612A1 (en) 2018-07-24 2020-01-30 Voyager Therapeutics, Inc. Systems and methods for producing gene therapy formulations
US10940290B2 (en) * 2018-08-27 2021-03-09 Alcyone Lifesciences, Inc. Fluid delivery systems and methods
AU2019327386A1 (en) * 2018-08-27 2021-03-18 Alcyone Therapeutics, Inc. Fluid delivery systems and methods
AU2019333136B2 (en) * 2018-08-29 2022-11-17 W. L. Gore & Associates, Inc. Drug therapy delivery systems and methods
US20200078509A1 (en) * 2018-09-12 2020-03-12 Xinova, LLC Micro-dispenser based ear treatment
EP3852653B1 (en) 2018-09-21 2023-11-08 CorFlow Therapeutics AG Apparatus for assessment of microvascular dysfunction
WO2020077165A1 (en) 2018-10-12 2020-04-16 Voyager Therapeutics, Inc. Compositions and methods for delivery of aav
US11857326B2 (en) * 2019-03-08 2024-01-02 Neuroone Medical Technologies Corporation Agent-delivering neural probe devices and related systems and methods
US20200305742A1 (en) * 2019-03-27 2020-10-01 Kamran Ghodsian System and method for child-birth monitoring and assistance
US12172037B2 (en) * 2019-08-15 2024-12-24 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for mechanogenetic functional ultrasound imaging
WO2021035190A1 (en) 2019-08-21 2021-02-25 Corflow Therapeutics Ag Controlled-flow infusion catheter and method
WO2021046155A1 (en) 2019-09-03 2021-03-11 Voyager Therapeutics, Inc. Vectorized editing of nucleic acids to correct overt mutations
WO2021176672A1 (ja) * 2020-03-05 2021-09-10 日本ライフライン株式会社 デリバリシャフトおよびデリバリシステム
US12435407B2 (en) 2020-08-03 2025-10-07 Neuroone Medical Technologies Corporation Methods for making probe devices and related devices
US11744939B2 (en) 2020-10-29 2023-09-05 Medtronic, Inc. Cyclic intrathecal drug delivery system and biomarker monitoring
JPWO2022181126A1 (enExample) * 2021-02-26 2022-09-01
WO2022241099A2 (en) * 2021-05-12 2022-11-17 Arizona Board Of Regents On Behalf Of The University Of Arizona In situ soil gas probes and sampling sytems
ES3031889T3 (en) * 2021-08-18 2025-07-11 Dixi Neurolab Inc Injectrode with multiple electrical sensors
WO2023091939A1 (en) * 2021-11-16 2023-05-25 Massachusetts Institute Of Technology Multifunctional microelectronics fibers as implantable bioelectronic interfaces
CN115869492A (zh) * 2022-05-26 2023-03-31 杭州堃博生物科技有限公司 介入系统、控制方法、计算机设备、程序产品以及存储介质
CN116999412A (zh) * 2023-08-03 2023-11-07 四川迈可隆生物科技有限公司 一种含有倍他米松药物的缓释微球制剂及其制备方法
WO2025184653A1 (en) * 2024-03-01 2025-09-04 Massachusetts Institute Of Technology Micro-invasive neural system for delivering therapeutic agents for the treatment of neurological disorders
CN117982146B (zh) * 2024-04-07 2024-07-12 华中科技大学 用于颅内肿瘤切除手术监测与治疗的水凝胶混合电子系统
CN119385986A (zh) * 2024-09-19 2025-02-07 江苏知原药业股份有限公司 一种特比萘芬成膜组合物的文丘里效应制备方法

Family Cites Families (189)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2830587A (en) 1954-02-01 1958-04-15 Everett Samuel James Hypodermic needles
US3460537A (en) 1966-09-26 1969-08-12 Donald C Zeis Stereotactic guide for use in the creation of destructive brain lesions
US3886948A (en) 1972-08-14 1975-06-03 Hakim Co Ltd Ventricular shunt having a variable pressure valve
US4146029A (en) 1974-04-23 1979-03-27 Ellinwood Jr Everett H Self-powered implanted programmable medication system and method
US4692146A (en) 1985-10-24 1987-09-08 Cormed, Inc. Multiple vascular access port
US4917686A (en) 1985-12-16 1990-04-17 Colorado Biomedical, Inc. Antimicrobial device and method
EP0343237B1 (en) 1987-12-05 1992-06-17 Renishaw plc Apparatus for changing a sensing device
US4885945A (en) 1988-02-23 1989-12-12 Activational Systems, Inc. Micropipettes and fabrication thereof
US5088208A (en) 1988-10-11 1992-02-18 Renishaw Plc Measurement probe for position determining apparatus
US5407431A (en) 1989-07-11 1995-04-18 Med-Design Inc. Intravenous catheter insertion device with retractable needle
US5695518A (en) 1990-12-28 1997-12-09 Laerum; Frode Filtering device for preventing embolism and/or distension of blood vessel walls
US5868711A (en) 1991-04-29 1999-02-09 Board Of Regents, The University Of Texas System Implantable intraosseous device for rapid vascular access
US5190046A (en) 1992-05-01 1993-03-02 Shturman Cardiology Systems, Inc. Ultrasound imaging balloon catheter
US5620479A (en) 1992-11-13 1997-04-15 The Regents Of The University Of California Method and apparatus for thermal therapy of tumors
US5415648A (en) 1993-07-08 1995-05-16 Malay; Manuel R. Multiple purpose syringe
US5954651A (en) 1993-08-18 1999-09-21 Scimed Life Systems, Inc. Catheter having a high tensile strength braid wire constraint
AU7676894A (en) 1993-08-27 1995-03-21 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Convection-enhanced drug delivery
US5509910A (en) 1994-05-02 1996-04-23 Medtronic, Inc. Method of soft tip attachment for thin walled catheters
US5604976A (en) 1994-10-18 1997-02-25 Pi Medical Corporation Method of making percutaneous connector for multi-conductor electrical cables
US6176842B1 (en) 1995-03-08 2001-01-23 Ekos Corporation Ultrasound assembly for use with light activated drugs
US5954687A (en) 1995-04-28 1999-09-21 Medtronic, Inc. Burr hole ring with catheter for use as an injection port
US6454945B1 (en) 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
WO1997000442A1 (en) 1995-06-16 1997-01-03 The University Of Washington Microfabricated differential extraction device and method
US5624396A (en) 1995-10-30 1997-04-29 Micro Therapeutics, Inc. Longitudinally extendable infusion device
US5590657A (en) 1995-11-06 1997-01-07 The Regents Of The University Of Michigan Phased array ultrasound system and method for cardiac ablation
US5979453A (en) 1995-11-09 1999-11-09 Femrx, Inc. Needle myolysis system for uterine fibriods
US5735814A (en) 1996-04-30 1998-04-07 Medtronic, Inc. Techniques of treating neurodegenerative disorders by brain infusion
BR9601849A (pt) 1996-06-18 1998-09-01 Newton Paes Aperfeiçoamento em cateter de dupla via para lavagem drenagem monitoração e controle de pressão intracraniana
US6193963B1 (en) 1996-10-17 2001-02-27 The Regents Of The University Of California Method of treating tumor-bearing patients with human plasma hyaluronidase
JP2001525703A (ja) 1997-05-15 2001-12-11 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 磁気共鳴画像化を使用する患者への標的投薬のための方法および装置
US7048716B1 (en) 1997-05-15 2006-05-23 Stanford University MR-compatible devices
US6061587A (en) 1997-05-15 2000-05-09 Regents Of The University Of Minnesota Method and apparatus for use with MR imaging
US6610235B1 (en) * 1997-06-30 2003-08-26 The Regents Of The University Of California Method of fabricating epidermal abrasion device
AU8681098A (en) 1997-08-01 1999-03-08 Massachusetts Institute Of Technology Three-dimensional polymer matrices
US5963367A (en) * 1997-09-23 1999-10-05 Lucent Technologies, Inc. Micromechanical xyz stage for use with optical elements
US5843150A (en) 1997-10-08 1998-12-01 Medtronic, Inc. System and method for providing electrical and/or fluid treatment within a patient's brain
EP1024832A1 (en) 1997-10-24 2000-08-09 Children's Medical Center Corporation METHODS FOR PROMOTING CELL TRANSFECTION $i(IN VIVO)
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
US20020055702A1 (en) 1998-02-10 2002-05-09 Anthony Atala Ultrasound-mediated drug delivery
US5957912A (en) 1998-04-16 1999-09-28 Camino Neurocare, Inc. Catheter having distal stylet opening and connector
ES2326893T3 (es) 1998-05-27 2009-10-21 Genzyme Corporation Vectores aav para la fabricacion de medicamentos para administracion potenciada por conveccion.
US6547779B2 (en) * 1998-07-22 2003-04-15 Endovasix, Inc. Flexible flow apparatus and method for the disruption of occlusions
US20030009153A1 (en) 1998-07-29 2003-01-09 Pharmasonics, Inc. Ultrasonic enhancement of drug injection
ATE308353T1 (de) 1999-03-03 2005-11-15 Uab Research Foundation Für das zentrale nervensystem bestimmer katheter mit temperaturkontrollsystem
US6464687B1 (en) * 1999-03-09 2002-10-15 Ball Semiconductor, Inc. Implantable drug delivery system
US6224566B1 (en) 1999-05-04 2001-05-01 Cardiodyne, Inc. Method and devices for creating a trap for confining therapeutic drugs and/or genes in the myocardium
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6599274B1 (en) * 2000-01-20 2003-07-29 John Kucharczyk Cell delivery catheter and method
DE10008825C2 (de) 2000-02-25 2002-11-21 Disetronic Licensing Ag Mikroperfusionsvorrichtung
US6626902B1 (en) * 2000-04-12 2003-09-30 University Of Virginia Patent Foundation Multi-probe system
US7473244B2 (en) 2000-06-02 2009-01-06 The University Of Utah Research Foundation Active needle devices with integrated functionality
EP1573416A4 (en) 2000-07-07 2010-01-27 Fenwal Inc MEDICAL SYSTEM, METHOD AND DEVICE USING MEMS
US6464662B1 (en) 2000-07-26 2002-10-15 Image-Guided Neurologics, Inc. Drug delivery and catheter systems, apparatus and processes
GB0019200D0 (en) 2000-08-05 2000-09-27 Renishaw Plc Bearing arrangement
US6902564B2 (en) 2001-08-15 2005-06-07 Roy E. Morgan Methods and devices for electrosurgery
US7445619B2 (en) 2000-08-18 2008-11-04 Map Technologies Llc Devices for electrosurgery
WO2002068036A1 (en) 2000-12-27 2002-09-06 The General Hospital Corporation Dual balloon catheter with sensor for continuosu transvenous measurmentof intracranial pressure
US7914470B2 (en) 2001-01-12 2011-03-29 Celleration, Inc. Ultrasonic method and device for wound treatment
US20020099356A1 (en) 2001-01-19 2002-07-25 Unger Evan C. Transmembrane transport apparatus and method
US7029697B2 (en) 2001-02-14 2006-04-18 Northwestern University Controlled surface-associated delivery of genes and oligonucleotides
US6623444B2 (en) * 2001-03-21 2003-09-23 Advanced Medical Applications, Inc. Ultrasonic catheter drug delivery method and device
WO2002085431A2 (en) 2001-04-24 2002-10-31 Neuron Therapeutics, Inc. Method of delivering liquid through cerebral spinal pathway
US6740058B2 (en) * 2001-06-08 2004-05-25 Wisconsin Alumni Research Foundation Surgical tool with integrated pressure and flow sensors
US20030138403A1 (en) * 2001-06-29 2003-07-24 Maxygen Aps Interferon formulations
US7150737B2 (en) 2001-07-13 2006-12-19 Sci/Med Life Systems, Inc. Methods and apparatuses for navigating the subarachnoid space
US6803568B2 (en) * 2001-09-19 2004-10-12 Predicant Biosciences, Inc. Multi-channel microfluidic chip for electrospray ionization
US20030148539A1 (en) 2001-11-05 2003-08-07 California Institute Of Technology Micro fabricated fountain pen apparatus and method for ultra high density biological arrays
US6971999B2 (en) 2001-11-14 2005-12-06 Medical Instill Technologies, Inc. Intradermal delivery device and method
AU2002367296A1 (en) 2001-12-28 2003-07-24 Ekos Corporation Multi-resonant ultrasonic catheter
US20070005017A1 (en) 2002-02-04 2007-01-04 Becton, Dickinson And Company Intradermal delivery device with crenellated skin engaging surface geometry
JP2005517180A (ja) 2002-02-05 2005-06-09 ザ ユニヴァーシティー コート オブ ザ ユニヴァーシティー オブ グラスゴー 細胞検定を実施するための装置
GB0205773D0 (en) 2002-03-12 2002-04-24 Gill Steven S Clamp
GB0205772D0 (en) 2002-03-12 2002-04-24 Gill Steven S Catheter
GB0208627D0 (en) 2002-04-16 2002-05-22 Imprint Pharm Ltd Needle
US20030199831A1 (en) 2002-04-23 2003-10-23 Morris Mary M. Catheter anchor system and method
GB2389791B (en) 2002-04-30 2006-12-13 Steven Gill Implantable drug delivery pump
US6784600B2 (en) * 2002-05-01 2004-08-31 Koninklijke Philips Electronics N.V. Ultrasonic membrane transducer for an ultrasonic diagnostic probe
US7771387B2 (en) 2002-05-17 2010-08-10 Boston Scientific Scimed, Inc. Liquid embolic composition delivery devices and methods
US7316676B2 (en) 2002-08-20 2008-01-08 Gholam A. Peyman Treatment of retinal detachment
EP1590034B1 (en) 2002-10-07 2014-05-14 Biovalve Technologies, Inc. Microneedle array patch
US7034854B2 (en) 2002-11-12 2006-04-25 Nanoink, Inc. Methods and apparatus for ink delivery to nanolithographic probe systems
EP1581285B1 (en) 2002-12-23 2009-02-25 Medtronic, Inc. Drug solution density adjustment systems and methods
US8946151B2 (en) 2003-02-24 2015-02-03 Northern Bristol N.H.S. Trust Frenchay Hospital Method of treating Parkinson's disease in humans by convection-enhanced infusion of glial cell-line derived neurotrophic factor to the putamen
EP1462141B1 (en) * 2003-03-26 2006-09-20 Terumo Kabushiki Kaisha Catheter with puncture sensor
US7963956B2 (en) 2003-04-22 2011-06-21 Antisense Pharma Gmbh Portable equipment for administration of fluids into tissues and tumors by convection enhanced delivery technique
US8886273B2 (en) * 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
EP1684861B1 (en) * 2003-10-21 2014-12-03 The Regents Of The University Of Michigan Intracranial neural interface system
GB0324519D0 (en) 2003-10-21 2003-11-26 Renishaw Plc Metrology instruments
US20050149049A1 (en) 2003-10-23 2005-07-07 Assell Robert L. Exchange system for soft tissue access pathway
WO2005083390A1 (en) * 2004-02-20 2005-09-09 Research Foundation Of The State University Of New York Method and device for manipulating liquids in microfluidic systems
US7775087B2 (en) * 2004-03-16 2010-08-17 Northwestern University Microchannel forming method and nanotipped dispensing device having a microchannel
US20050236566A1 (en) * 2004-04-26 2005-10-27 Chang Liu Scanning probe microscope probe with integrated capillary channel
CA2564876C (en) * 2004-04-30 2013-04-16 Bioforce Nanosciences, Inc. Method and apparatus for depositing material onto a surface
US8992454B2 (en) 2004-06-09 2015-03-31 Bard Access Systems, Inc. Splitable tip catheter with bioresorbable adhesive
US7727225B2 (en) * 2004-07-28 2010-06-01 University Of Virginia Patent Foundation Coaxial catheter systems for transference of medium
CN101123919A (zh) * 2004-10-05 2008-02-13 建新公司 台阶式插管
CA2581714C (en) 2004-10-05 2017-09-12 Avigen, Inc. Stepped cannula
US7729780B2 (en) 2004-10-21 2010-06-01 Vardiman Arnold B Various apparatus and methods for deep brain stimulating electrodes
AU2006200951B2 (en) 2005-03-13 2012-01-19 Integra LifeSciences Switzerland Sarl Pressure sensing devices
US7510533B2 (en) 2005-03-15 2009-03-31 Codman & Shurtleff, Inc. Pressure sensing valve
US10362947B2 (en) 2005-03-15 2019-07-30 Integra LifeSciences Switzerland Sarl Pressure sensing devices
US20060211945A1 (en) 2005-03-15 2006-09-21 Codman & Shurtleff, Inc. Pressure sensing methods
GB0512078D0 (en) 2005-06-14 2005-07-20 Gill Steven S RF Coil structure
US7717853B2 (en) 2005-06-24 2010-05-18 Henry Nita Methods and apparatus for intracranial ultrasound delivery
US7615050B2 (en) 2005-06-27 2009-11-10 Boston Scientific Scimed, Inc. Systems and methods for creating a lesion using transjugular approach
US20070128083A1 (en) 2005-07-18 2007-06-07 U.S. Genomics, Inc. Microfluidic methods and apparatuses for sample preparation and analysis
WO2007024841A2 (en) 2005-08-23 2007-03-01 The Regents Of The University Of California Reflux resistant cannula and system for chronic delivery of therapeutic agents using convection-enhanced delivery
US7967763B2 (en) 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US8182444B2 (en) * 2005-11-04 2012-05-22 Medrad, Inc. Delivery of agents such as cells to tissue
US20070191767A1 (en) * 2005-12-16 2007-08-16 Medtronic Vascular, Inc. Bifurcated Catheter Joints
US8206334B2 (en) * 2006-01-31 2012-06-26 Kralick Francis A Implantable micro-system for treatment of hydrocephalus
GB0603037D0 (en) 2006-02-15 2006-03-29 Renishaw Plc Implantable fluid distribution device and a method of drug delivery
GB0604952D0 (en) 2006-03-13 2006-04-19 Renishaw Plc A fluid connector for fluid delivery apparatus
GB0604929D0 (en) 2006-03-13 2006-04-19 Renishaw Plc Method and apparatus for fluid delivery
US8795270B2 (en) 2006-04-24 2014-08-05 Covidien Ag System and method for ablating tissue
WO2007133545A2 (en) 2006-05-11 2007-11-22 Ceramoptec Industries, Inc. Device and method for improved vascular laser treatment
US20100030102A1 (en) 2006-05-15 2010-02-04 David Poston Active Delivery and Flow Redirections: Novel Devices and Method of Delivery of Materials to Patients
US7998128B2 (en) 2006-05-15 2011-08-16 Therataxis, LLC. Active delivery and flow redirection: novel devices and method of delivery of materials to patients
GB0612980D0 (en) 2006-06-30 2006-08-09 Renishaw Plc Gas bearings
GB0612979D0 (en) 2006-06-30 2006-08-09 Renishaw Plc Gas bearing fabrication method
WO2008005440A2 (en) 2006-06-30 2008-01-10 University Of Illinois Monitoring and controlling hydrocephalus
GB0616411D0 (en) 2006-08-18 2006-09-27 Renishaw Plc Neurosurgical instruments
US8403858B2 (en) * 2006-10-12 2013-03-26 Perceptive Navigation Llc Image guided catheters and methods of use
KR20130014619A (ko) * 2006-11-03 2013-02-07 리써치 트라이앵글 인스티튜트 굴곡 모드 압전 트랜스듀서를 사용하는 보강된 초음파 촬영 프로브
US7842006B2 (en) * 2006-11-17 2010-11-30 Cfd Research Corporation Thrombectomy microcatheter
GB0623395D0 (en) 2006-11-23 2007-01-03 Renishaw Plc Port
CN101657189B (zh) 2007-02-13 2014-11-26 康奈尔大学 对流增强型递送装置,方法和应用
WO2008106357A1 (en) * 2007-02-27 2008-09-04 Regents Of The University Of Minnesota Thermochemical ablation of bodily tissue
US20080275466A1 (en) 2007-05-01 2008-11-06 James Grant Skakoon Dual cannula system and method for using same
US7870616B2 (en) * 2007-05-11 2011-01-11 Csem Centre Suisse D'electronique Et De Microtechnique Sa Probe arrangement
WO2008144585A1 (en) 2007-05-17 2008-11-27 Medgenesis Therapeutix Inc. Convection-enhanced delivery catheter with removable stiffening member and method for using same
US20100121307A1 (en) * 2007-08-24 2010-05-13 Microfabrica Inc. Microneedles, Microneedle Arrays, Methods for Making, and Transdermal and/or Intradermal Applications
US8147480B2 (en) 2007-09-28 2012-04-03 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US7766875B2 (en) 2007-09-28 2010-08-03 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
WO2009045343A1 (en) 2007-09-29 2009-04-09 El Spectra, Llc Instrumented pipette tip
CA2701132A1 (en) 2007-10-08 2009-04-16 Renishaw (Ireland) Limited Apparatus for stereotactic neurosurgery
WO2009047490A2 (en) 2007-10-08 2009-04-16 Renishaw Plc Catheter
GB0802634D0 (en) 2008-02-13 2008-03-19 Renishaw Plc Catheter
GB0719608D0 (en) 2007-10-08 2007-11-14 Renishaw Plc Medical Apparatus
US20090112278A1 (en) 2007-10-30 2009-04-30 Neuropace, Inc. Systems, Methods and Devices for a Skull/Brain Interface
EP2060287B1 (de) 2007-11-14 2011-06-15 BrainLAB AG Medikamentenzuführungssystem für CED (Convection Enhanced Delivery)-Katheterinfusionen
US8480626B2 (en) * 2007-11-30 2013-07-09 Medtronic, Inc. Infusion catheter assembly with reduced backflow
WO2009086624A1 (en) 2008-01-04 2009-07-16 The Royal Institution For The Advancement Of Learning/Mcgill University Microfluidic microarray system and method for the multiplexed analysis of biomolecules
ES2596360T3 (es) 2008-01-16 2017-01-09 Neurodyn Life Sciences Inc. Progranulina para su uso en el tratamiento de enfermedad de Parkinson o enfermedad de Alzheimer
WO2010005479A1 (en) 2008-06-16 2010-01-14 Wayne State University Method of making 3-dimensional neural probes having electrical and chemical interfaces
US9138559B2 (en) 2008-06-16 2015-09-22 Twin Star Medical, Inc Flexible catheter
WO2010006293A2 (en) 2008-07-10 2010-01-14 Cornell University Ultrasound wave generating apparatus
NL2003364A (en) 2008-09-26 2010-03-29 Asml Netherlands Bv Lithographic apparatus and method.
US8539905B2 (en) * 2008-11-07 2013-09-24 The Research Foundation For The State University Of New York Polymeric micro-cantilevers for ultra-low volume fluid and living cell deposition
US8540667B2 (en) 2008-11-12 2013-09-24 Sanovas, Inc. Multi-balloon catheter for extravasated drug delivery
GB0820839D0 (en) 2008-11-13 2008-12-24 Renishaw Plc Assessing and/or correcting tomogram errors
US9402974B2 (en) 2009-01-12 2016-08-02 Becton, Dickinson And Company Optimized intracranial catheters for convection-enhanced delivery of therapeutics
US8784360B2 (en) 2009-01-21 2014-07-22 Medtronic, Inc. Catheter systems having flow restrictors
US20100185179A1 (en) * 2009-01-21 2010-07-22 Abbott Cardiovascular Systems Inc. Needled cannula with filter device
TWI449551B (zh) 2009-01-30 2014-08-21 Terumo Corp 注射針組合體以及藥劑注射裝置
JP5838093B2 (ja) 2009-02-24 2015-12-24 クライン,ジョージ 固定カテーテルシース
EP3827858A1 (en) 2009-03-03 2021-06-02 Becton, Dickinson and Company Pen needle assembly for delivering drug solutions
US8602644B2 (en) 2009-05-08 2013-12-10 University Of North Texas Multifunctional micropipette biological sensor
GB0908787D0 (en) 2009-05-21 2009-07-01 Renishaw Plc Head clamp for imaging and neurosurgery
GB0908784D0 (en) 2009-05-21 2009-07-01 Renishaw Plc Apparatus for imaging a body part
US20110003330A1 (en) 2009-07-06 2011-01-06 Durack Gary P Microfluidic device
CA2771175C (en) * 2009-08-25 2017-12-05 The Regents Of The Univeristy Of California Optimized placement of cannula for delivery of therapeutics to the brain
US9936884B2 (en) 2009-10-28 2018-04-10 Megan Mikhail Method and system for treating hypotension
US9498271B2 (en) * 2009-10-29 2016-11-22 Cook Medical Technologies Llc Coaxial needle cannula with distal spiral mixer and side ports for fluid injection
US8814853B2 (en) 2009-10-29 2014-08-26 Cook Medical Technologies Llc Thermochemical ablation needle
US20110301235A1 (en) 2009-12-02 2011-12-08 Alquest Therapeutics, Inc. Organoselenium compounds and uses thereof
GB201002370D0 (en) 2010-02-12 2010-03-31 Renishaw Ireland Ltd Percutaneous drug delivery apparatus
US10537725B2 (en) * 2010-03-05 2020-01-21 Cornell University Ultrasound-assisted convection enhanced delivery of compounds in vivo with a transducer cannula assembly
CN102844064A (zh) 2010-03-31 2012-12-26 泰尔茂株式会社 预灌封注射器
JP2013540981A (ja) 2010-04-30 2013-11-07 レニショウ パブリック リミテッド カンパニー 計測装置
US20120019270A1 (en) 2010-07-21 2012-01-26 Amodei Dario G Microfabricated pipette and method of manufacture
US9498248B2 (en) 2010-10-05 2016-11-22 Medtronic, Inc. Retainer for immobilizing an implanted catheter during stylet retraction, and stylet holder for use with same
WO2012068283A1 (en) 2010-11-16 2012-05-24 C2C Development, Llc Seal tip catheter devices or methods
EP2672903A4 (en) 2011-02-10 2017-07-12 Actuated Medical, Inc. Medical tool with electromechanical control and feedback
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
US9138343B2 (en) 2011-05-31 2015-09-22 Bayer Healthcare Llc Tip protector sleeve
CA3125150A1 (en) 2011-08-01 2013-02-07 Alcyone Lifesciences, Inc. Microfluidic drug delivery devices
US20130079596A1 (en) 2011-09-23 2013-03-28 Todd Edward Smith Dynamic surgical fluid sensing
US8753344B2 (en) * 2011-09-23 2014-06-17 Smith & Nephew, Inc. Dynamic orthoscopic sensing
US9539389B2 (en) 2012-02-08 2017-01-10 Stmicroelectronics, Inc. Wireless flow sensor using present flow rate data
US9255245B2 (en) * 2012-07-03 2016-02-09 Agilent Technologies, Inc. Sample probes and methods for sampling intracellular material
US10751513B2 (en) 2012-07-24 2020-08-25 Renishaw Plc Neurosurgical apparatus and methods
US10188396B2 (en) 2012-08-06 2019-01-29 Covidien Lp Apparatus and method for delivering an embolic composition
US9919129B2 (en) 2012-12-18 2018-03-20 Alcyone Lifesciences, Inc. Systems and methods for reducing or preventing backflow in a delivery system
US9539382B2 (en) 2013-03-12 2017-01-10 Medtronic, Inc. Stepped catheters with flow restrictors and infusion systems using the same
WO2014204954A1 (en) 2013-06-17 2014-12-24 Alcyone Lifesciences, Inc. Methods and devices for protecting catheter tips and stereotactic fixtures for microcatheters
ES2738298T3 (es) 2013-07-31 2020-01-21 Alcyone Lifesciences Inc Sistemas y métodos de suministro de fármacos, tratamiento y monitoreo
US10806396B2 (en) 2015-01-26 2020-10-20 Alcyone Lifesciences, Inc. Drug delivery methods with tracer
WO2016183123A1 (en) * 2015-05-11 2016-11-17 Alcyone Lifesciences, Inc. Drug delivery systems and methods

Similar Documents

Publication Publication Date Title
JP2014529417A5 (enExample)
ES2738298T3 (es) Sistemas y métodos de suministro de fármacos, tratamiento y monitoreo
JP6941088B2 (ja) 微小成型装置
WO2009023798A3 (en) Needle array assembly and method for delivering therapeutic agents
CN106455904B (zh) 介入性窦内窥镜
JP2012525181A5 (enExample)
ATE514451T1 (de) Katheter mit porösen ballon
JP2011509158A5 (enExample)
EP3145568B1 (en) Device to reduce discomfort in the upper airway
TW200613029A (en) System and method for drug delivery and microfluidic applications using microneedles
MX2014007208A (es) Modificacion en la superficie para cateteres de dialisis.
WO2011064780A3 (en) Analyte monitoring and fluid dispensing system
IL199862A0 (en) Catheter with perforated tip
JP2016538052A5 (enExample)
JP2013516217A5 (enExample)
CN205903515U (zh) 一种球囊扩张导管
WO2014089519A1 (en) System for reducing local discomfort
CN107303406A (zh) 一种球囊扩张导管
JP6297494B2 (ja) マルチオリフィススプレーヘッド
JP2021520908A (ja) 経皮的腫瘍内治療送達のための装置および方法
WO2020064082A1 (en) Device comprising microneedles for skin-coloring
CN204502044U (zh) 具有润滑内涂层的血管微导管
CN204798598U (zh) 无痛导尿管
JP2016515004A5 (enExample)
CN204502043U (zh) 具有显影标记功能的血管微导管