JP2014527508A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014527508A5 JP2014527508A5 JP2014513726A JP2014513726A JP2014527508A5 JP 2014527508 A5 JP2014527508 A5 JP 2014527508A5 JP 2014513726 A JP2014513726 A JP 2014513726A JP 2014513726 A JP2014513726 A JP 2014513726A JP 2014527508 A5 JP2014527508 A5 JP 2014527508A5
- Authority
- JP
- Japan
- Prior art keywords
- substituent
- optionally substituted
- optionally
- membered
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161493250P | 2011-06-03 | 2011-06-03 | |
| US61/493,250 | 2011-06-03 | ||
| PCT/US2012/040379 WO2012167021A2 (en) | 2011-06-03 | 2012-06-01 | Hyperforin analogs, methods of synthesis, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014527508A JP2014527508A (ja) | 2014-10-16 |
| JP2014527508A5 true JP2014527508A5 (https=) | 2015-08-20 |
Family
ID=47260359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014513726A Pending JP2014527508A (ja) | 2011-06-03 | 2012-06-01 | ハイパーフォリン類似物、合成方法、およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9321713B2 (https=) |
| EP (1) | EP2714638A4 (https=) |
| JP (1) | JP2014527508A (https=) |
| KR (1) | KR20140041610A (https=) |
| CN (1) | CN103732568A (https=) |
| AU (1) | AU2012262084A1 (https=) |
| BR (1) | BR112013030986A2 (https=) |
| CA (1) | CA2837549A1 (https=) |
| IL (1) | IL229742A0 (https=) |
| MX (1) | MX2013014162A (https=) |
| RU (1) | RU2013157954A (https=) |
| SG (1) | SG195210A1 (https=) |
| WO (1) | WO2012167021A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103980231B (zh) * | 2014-06-04 | 2016-03-30 | 中国科学院上海有机化学研究所 | 一种五氟苯基环氧丙烷的合成方法 |
| US20180071269A1 (en) | 2015-08-12 | 2018-03-15 | Tianxin Wang | Therapeutical methods, formulations and nutraceutical formulations |
| CN106496171B (zh) * | 2016-10-20 | 2019-09-13 | 贵州省中国科学院天然产物化学重点实验室 | 具有抗肿瘤活性的多环多异戊烯基间苯三酚类化合物、其制备方法及应用 |
| CN106967016B (zh) * | 2017-04-25 | 2020-05-19 | 华中科技大学 | 贯叶连翘次生代谢产物中具有乙酰胆碱酯酶抑制作用化合物及分离制备和用途 |
| CN109044999A (zh) * | 2018-10-15 | 2018-12-21 | 上海市第六人民医院 | 贯叶金丝桃素在制备促进白色脂肪棕色化并且提高棕色脂肪活性的药物中的用途 |
| DE102022129895A1 (de) * | 2022-11-11 | 2024-05-16 | Technische Universität Dresden, Körperschaft des öffentlichen Rechts | 4-Hydroxybicyclo[3.3.1]non-3-en-2,9-dion-Derivate und deren Verwendung |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2320091A1 (en) | 1998-02-13 | 1999-08-19 | Dr. Willmar Schwabe Gmbh & Co. | Stable hyperforin salts, methods of manufacturing them, and their use for the treatment of alzheimer's disease |
| IT1301679B1 (it) * | 1998-06-10 | 2000-07-07 | Indena Spa | Derivati dell'iperforina, loro uso e formulazioni che licontengono. |
| WO2000054760A2 (en) * | 1999-03-15 | 2000-09-21 | Shaman Pharmaceuticals, Inc. | Bicyclo (3.3.1) nonenes useful for the treatment of diabetes and hypertriglyceridemia |
| AU3738700A (en) * | 1999-03-15 | 2000-10-04 | Shaman Pharmaceuticals, Inc. | Stabilized bicyclo(3.3.1)nonenes and methods of use |
| DE10157033A1 (de) * | 2001-11-21 | 2003-05-28 | Siegfried Seeber | Substituierte Bicyclo[3.3.1]nonan-2,4,9-trione als pharmazeutische Wirkstoffe |
| ITMI20020872A1 (it) * | 2002-04-23 | 2003-10-23 | Indena Spa | Derivati dell'iperforina loro uso e formulazioni che li contengono |
| ITMI20020871A1 (it) | 2002-04-23 | 2003-10-23 | Indena Spa | Derivati alogenati dell'iperforina loro uso e formulazioni che li contengono |
-
2012
- 2012-06-01 SG SG2013088257A patent/SG195210A1/en unknown
- 2012-06-01 MX MX2013014162A patent/MX2013014162A/es unknown
- 2012-06-01 US US14/123,255 patent/US9321713B2/en active Active
- 2012-06-01 JP JP2014513726A patent/JP2014527508A/ja active Pending
- 2012-06-01 BR BR112013030986A patent/BR112013030986A2/pt not_active IP Right Cessation
- 2012-06-01 AU AU2012262084A patent/AU2012262084A1/en not_active Abandoned
- 2012-06-01 RU RU2013157954/04A patent/RU2013157954A/ru not_active Application Discontinuation
- 2012-06-01 KR KR1020137034956A patent/KR20140041610A/ko not_active Withdrawn
- 2012-06-01 EP EP12794102.9A patent/EP2714638A4/en not_active Withdrawn
- 2012-06-01 CN CN201280037554.8A patent/CN103732568A/zh active Pending
- 2012-06-01 CA CA2837549A patent/CA2837549A1/en not_active Abandoned
- 2012-06-01 WO PCT/US2012/040379 patent/WO2012167021A2/en not_active Ceased
-
2013
- 2013-12-01 IL IL229742A patent/IL229742A0/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014527508A5 (https=) | ||
| ES2717226T3 (es) | Método de producción de beraprost | |
| CA3018959C (en) | Crystal forms and methods of synthesis of (2r, 6r)-hydroxynorketamine and (2s, 6s)-hydroxynorketamine | |
| JP2016515096A5 (https=) | ||
| UA101482C2 (ru) | Способ получения 2'-дезокси-5-азацитидина (децитабина) | |
| JP2012509905A (ja) | ビタミンｄ類似体の合成方法 | |
| RU2013138372A (ru) | Производные азетидина, применяемые для лечения метаболических и воспалительных заболеваний | |
| JP2011519360A5 (https=) | ||
| CN105777544A (zh) | 一种高光学纯度s-（+）-氟比洛芬酯的制备方法 | |
| JP2007530436A5 (https=) | ||
| ES2772500T3 (es) | Intermedios versátiles y funcionalizados para la síntesis de vitamina D y nuevos derivados de vitamina D | |
| CN109983037B (zh) | 光引发剂 | |
| Toyoda et al. | Synthesis and Z/E isomerization of 2-imino-1, 3-thiaselenolanes via iodocyclization | |
| CN110483417A (zh) | 一种DACOs类NNRTIs氨基酸酯衍生物、其制备方法、药物组合物及应用 | |
| KR20190009326A (ko) | 에리불린 및 그의 중간체의 제조방법 | |
| CN103408559B (zh) | 一种喜树碱及其衍生物的快速合成方法 | |
| ES2881899T3 (es) | Procedimiento de preparación de un inhibidor de fosfodiesterasa 4 | |
| CN105143162B (zh) | 合成方法 | |
| JP5943387B2 (ja) | 新規トリフロン誘導体及びその製造方法 | |
| RU2537390C1 (ru) | Способ получения 2-экзо-[3'-(6'-хлорпиридил)]-7-азабицикло[2.2.1]-гептана | |
| JP4811547B2 (ja) | 光学活性シクロヘキセン化合物の製造法及びこの製造に用いる光学活性シクロヘキセン誘導体 | |
| JP5218952B2 (ja) | 縮合環化合物及びその製造方法 | |
| JP2017066070A (ja) | メントール誘導体、その製造方法及びその用途 | |
| RU2485126C1 (ru) | 6'-арил-2'-(2-гидроксифенил)-11',11'-диметил-3',4,4',13'-тетраоксоспиро[2,5-циклогексадиен-1,9'-(7'-окса-2',12'-диазатетрацикло[6.5.1.01,5.08,12]тетрадец-5'-ен)]-14'-карбоксилаты и способ их получения | |
| JP6288588B2 (ja) | Ｎ−スルフィニル−α−アミノアミドの製造方法 |