JP2014527407A - 網膜変性疾患の処置方法 - Google Patents
網膜変性疾患の処置方法 Download PDFInfo
- Publication number
- JP2014527407A JP2014527407A JP2014523346A JP2014523346A JP2014527407A JP 2014527407 A JP2014527407 A JP 2014527407A JP 2014523346 A JP2014523346 A JP 2014523346A JP 2014523346 A JP2014523346 A JP 2014523346A JP 2014527407 A JP2014527407 A JP 2014527407A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- cell
- retinal
- wnt
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Virology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11176713A EP2554662A1 (en) | 2011-08-05 | 2011-08-05 | Methods of treatment of retinal degeneration diseases |
| EP11176713.3 | 2011-08-05 | ||
| PCT/EP2012/065327 WO2013020945A1 (en) | 2011-08-05 | 2012-08-06 | Methods of treatment of retinal degeneration diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014527407A true JP2014527407A (ja) | 2014-10-16 |
| JP2014527407A5 JP2014527407A5 (https=) | 2016-01-21 |
Family
ID=46826437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014523346A Pending JP2014527407A (ja) | 2011-08-05 | 2012-08-06 | 網膜変性疾患の処置方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20140199277A1 (https=) |
| EP (2) | EP2554662A1 (https=) |
| JP (1) | JP2014527407A (https=) |
| KR (1) | KR20140068936A (https=) |
| CN (1) | CN104011203A (https=) |
| AR (1) | AR087471A1 (https=) |
| AU (1) | AU2012293681A1 (https=) |
| BR (1) | BR112014002718A8 (https=) |
| CA (1) | CA2844106A1 (https=) |
| CO (1) | CO7081142A2 (https=) |
| IL (1) | IL230830A0 (https=) |
| MX (1) | MX2014001475A (https=) |
| RU (1) | RU2014108478A (https=) |
| SG (1) | SG2014008080A (https=) |
| WO (1) | WO2013020945A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013045694A1 (en) | 2011-09-29 | 2013-04-04 | The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Compositions and methods for the treatment of degenerative retinal conditions |
| KR102368751B1 (ko) | 2014-01-17 | 2022-03-03 | 스미또모 가가꾸 가부시끼가이샤 | 모양체 주연부 간세포의 제조 방법 |
| SG11201702055PA (en) * | 2014-09-16 | 2017-04-27 | Genzyme Corp | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
| RU2569481C1 (ru) * | 2014-12-25 | 2015-11-27 | федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Способ получения культуры клеток ретинального пигментного эпителия из глаза взрослого донора-трупа |
| RU2578526C1 (ru) * | 2014-12-25 | 2016-03-27 | федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Способ получения органной культуры хороидально-пигментного комплекса из глаза взрослого донора-трупа |
| KR101779932B1 (ko) * | 2015-09-15 | 2017-09-21 | 주식회사 스템랩 | 나노그(Nanog)를 도입한 양수 내 태아 유래 중간엽 줄기세포를 이용한 육모 촉진용 조성물의 제조방법 |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| KR101674622B1 (ko) * | 2016-07-07 | 2016-11-09 | 국민대학교산학협력단 | 세스퀴테르펜 유도체의 신규한 용도 |
| AU2017312499B2 (en) * | 2016-08-19 | 2023-02-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration |
| JP6779546B2 (ja) * | 2016-11-06 | 2020-11-04 | ナノスコープ テクノロジーズ エルエルシーNanoscope Technologies Llc | 視力回復のための多特性オプシンによる光遺伝学的調節及びその別の用途 |
| BR112019022447A2 (pt) | 2017-04-27 | 2020-06-09 | Retinopathy Answer Limited | sistema e método para análise de imagem funduscópica automatizada |
| US11839613B2 (en) | 2017-05-18 | 2023-12-12 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives as PGE2 receptor modulators |
| PE20191814A1 (es) | 2017-05-18 | 2019-12-27 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores del receptor de pge2 |
| KR102612140B1 (ko) | 2017-05-18 | 2023-12-08 | 이도르시아 파마슈티컬스 리미티드 | 피리미딘 유도체 |
| TW201900179A (zh) | 2017-05-18 | 2019-01-01 | 瑞士商愛杜西亞製藥有限公司 | 作為pge2受體調節劑之苯并呋喃及苯并噻吩衍生物 |
| TWI768043B (zh) | 2017-05-18 | 2022-06-21 | 瑞士商愛杜西亞製藥有限公司 | N-取代吲哚衍生物 |
| JP7376092B2 (ja) * | 2017-06-15 | 2023-11-08 | ザ ユニバーシティ オブ ノース テキサス ヘルス サイエンス センター アット フォート ワース | 網膜細胞への線維芽細胞の再プログラミング方法 |
| CN111132664A (zh) * | 2017-08-20 | 2020-05-08 | 加州大学董事会 | 治疗青光眼的Wnt5a的调节 |
| US20220040236A1 (en) * | 2018-04-06 | 2022-02-10 | Icahn School Of Medicine At Mount Sinai | Compositions and methods of treatment of vision loss through generation of rod photoreceptors from müller glial cells |
| EP3937955A4 (en) * | 2019-03-15 | 2022-12-07 | The Schepens Eye Research Institute, Inc. | ISOLATION, ENHANCEMENT AND EXPANSION OF CONICAL PROGENITOR CELLS AND THEIR USES |
| CN110706164A (zh) * | 2019-09-03 | 2020-01-17 | 北京爱博同心医学科技有限公司 | 基于增强现实的管状视野图像变形显示方法及眼镜 |
| WO2021062022A1 (en) * | 2019-09-25 | 2021-04-01 | The Board Of Trustees Of The Leland Stanford Junior University | Metabolic rescue of retinal degeneration |
| KR20210119766A (ko) * | 2020-03-25 | 2021-10-06 | 서울대학교병원 | 인간 배아줄기세포 유래 중간엽 줄기세포를 포함하는 망막색소변성의 예방 또는 치료용 약학적 조성물 |
| KR102655748B1 (ko) * | 2023-06-08 | 2024-04-05 | 충북대학교 산학협력단 | 고포도당 조건에서의 중간엽 줄기세포의 생존율을 증가시키는 방법 |
| KR102655735B1 (ko) * | 2023-06-09 | 2024-04-05 | 충북대학교 산학협력단 | 당뇨성 망막병증의 예방 및 치료를 위한 타크로리무스 전처리 줄기세포 |
| WO2025229177A1 (en) | 2024-05-02 | 2025-11-06 | Idorsia Pharmaceuticals Ltd | Crystalline forms of an n-substituted indole derivative |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060147435A1 (en) * | 2004-12-30 | 2006-07-06 | Moon Randall T | Methods for regulation of stem cells |
| JP2008512376A (ja) * | 2004-09-03 | 2008-04-24 | ザ・スクリプス・リサーチ・インステイチユート | 単離された系統陰性造血幹細胞及びこれを用いた治療方法 |
| JP2009500297A (ja) * | 2005-06-08 | 2009-01-08 | セントカー・インコーポレーテツド | 眼の変性についての細胞療法 |
| JP2010509916A (ja) * | 2006-11-16 | 2010-04-02 | ザ スクリップス リサーチ インスティテュート | 単離された骨髄球様細胞集団及びそれを用いた治療方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6128654A (en) | 1997-02-14 | 2000-10-03 | Advanced Micro Devices, Inc. | Method and apparatus for transmitting multiple copies by replicating data identifiers |
| WO1999065897A1 (en) | 1998-06-19 | 1999-12-23 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| CN100335479C (zh) | 1999-12-17 | 2007-09-05 | 希龙公司 | 糖元合成酶激酶3的双环抑制剂 |
| JP2003516974A (ja) | 1999-12-17 | 2003-05-20 | カイロン コーポレイション | グリコーゲンシンターゼキナーゼ3のピラジンベースインヒビター |
| AU9502601A (en) | 2000-09-06 | 2002-03-22 | Chiron Corp | Inhibitors of glycogen synthase kinase 3 |
| DE60115069T2 (de) | 2000-09-11 | 2006-08-03 | Chiron Corp., Emeryville | Chinolinonderivate als tyrosin-kinase inhibitoren |
| ES2274035T3 (es) | 2001-06-01 | 2007-05-16 | Vertex Pharmaceuticals Incorporated | Compuestos de tiazol utiles como inhibidores de proteina quinasas. |
| WO2003066629A2 (en) | 2002-02-06 | 2003-08-14 | Vertex Pharmaceuticals Incorporated | Heteroaryl compounds useful as inhibitors of gsk-3 |
| WO2003074072A1 (en) | 2002-03-01 | 2003-09-12 | Chiron Corporation | Methods and compositions for the treatment of ischemia |
| US7838290B2 (en) * | 2002-07-25 | 2010-11-23 | The Scripps Research Institute | Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith |
| US20050129665A1 (en) | 2002-07-25 | 2005-06-16 | Martin Friedlander | Isolated lineage negative hematopoietic stem cells and methods of treatment therewith |
| DE60333762D1 (de) | 2002-08-23 | 2010-09-23 | Novartis Vaccines & Diagnostic | Pyrrolverbindungen als glykogen synthase kinase 3 inhibitoren |
| CN1717391A (zh) | 2002-10-21 | 2006-01-04 | 希龙公司 | 糖元合成酶激酶3的抑制剂 |
| CA2524063C (en) * | 2003-05-02 | 2015-02-17 | The Scripps Research Institute | Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith |
| KR20060056377A (ko) | 2003-08-13 | 2006-05-24 | 카이론 코포레이션 | Gsk-3 억제제 및 그것의 사용 |
| US20080317721A1 (en) | 2005-02-24 | 2008-12-25 | The Scripps Research Institute | Method for the Treatment of Retinopathy of Prematurity and Related Retinopathic Diseases |
| EP2171043B1 (en) * | 2007-06-15 | 2015-03-18 | Garnet BioTherapeutics, Inc | Treatment of diseases and disorders using self-renewing colony forming cells cultured and expanded in vitro |
| EP2090649A1 (en) | 2008-02-13 | 2009-08-19 | Fondazione Telethon | Method for reprogramming differentiated cells |
| GB0816577D0 (en) * | 2008-09-11 | 2008-10-15 | Axordia Ltd | Growth factor |
| EP2486126B1 (en) * | 2009-10-06 | 2017-12-06 | SNU R & DB Foundation | Method for differentiation into retinal cells from stem cells |
-
2011
- 2011-08-05 EP EP11176713A patent/EP2554662A1/en not_active Withdrawn
-
2012
- 2012-08-06 SG SG2014008080A patent/SG2014008080A/en unknown
- 2012-08-06 EP EP12756386.4A patent/EP2739723A1/en not_active Withdrawn
- 2012-08-06 BR BR112014002718A patent/BR112014002718A8/pt not_active IP Right Cessation
- 2012-08-06 AR ARP120102872A patent/AR087471A1/es unknown
- 2012-08-06 CA CA2844106A patent/CA2844106A1/en not_active Abandoned
- 2012-08-06 CN CN201280049453.2A patent/CN104011203A/zh active Pending
- 2012-08-06 JP JP2014523346A patent/JP2014527407A/ja active Pending
- 2012-08-06 US US14/237,297 patent/US20140199277A1/en not_active Abandoned
- 2012-08-06 WO PCT/EP2012/065327 patent/WO2013020945A1/en not_active Ceased
- 2012-08-06 AU AU2012293681A patent/AU2012293681A1/en not_active Abandoned
- 2012-08-06 RU RU2014108478/10A patent/RU2014108478A/ru not_active Application Discontinuation
- 2012-08-06 KR KR1020147006060A patent/KR20140068936A/ko not_active Withdrawn
- 2012-08-06 MX MX2014001475A patent/MX2014001475A/es not_active Application Discontinuation
-
2014
- 2014-02-05 IL IL230830A patent/IL230830A0/en unknown
- 2014-03-05 CO CO14047158A patent/CO7081142A2/es unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008512376A (ja) * | 2004-09-03 | 2008-04-24 | ザ・スクリプス・リサーチ・インステイチユート | 単離された系統陰性造血幹細胞及びこれを用いた治療方法 |
| US20060147435A1 (en) * | 2004-12-30 | 2006-07-06 | Moon Randall T | Methods for regulation of stem cells |
| JP2009500297A (ja) * | 2005-06-08 | 2009-01-08 | セントカー・インコーポレーテツド | 眼の変性についての細胞療法 |
| JP2010509916A (ja) * | 2006-11-16 | 2010-04-02 | ザ スクリップス リサーチ インスティテュート | 単離された骨髄球様細胞集団及びそれを用いた治療方法 |
Non-Patent Citations (2)
| Title |
|---|
| JPN6016011403; INOUE T. et al.: STEM CELLS Vol.24, 2006, p.95-104 * |
| JPN6016011405; OSAKADA F. et al.: J Neurosci Vol.27, 2007, p.4210-219 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2014001475A (es) | 2014-07-22 |
| WO2013020945A1 (en) | 2013-02-14 |
| SG2014008080A (en) | 2014-03-28 |
| BR112014002718A2 (pt) | 2017-06-13 |
| AR087471A1 (es) | 2014-03-26 |
| CN104011203A (zh) | 2014-08-27 |
| WO2013020945A9 (en) | 2013-04-04 |
| KR20140068936A (ko) | 2014-06-09 |
| BR112014002718A8 (pt) | 2017-06-20 |
| CO7081142A2 (es) | 2014-10-10 |
| NZ621345A (en) | 2015-09-25 |
| CA2844106A1 (en) | 2013-02-14 |
| RU2014108478A (ru) | 2015-09-10 |
| US20140199277A1 (en) | 2014-07-17 |
| EP2554662A1 (en) | 2013-02-06 |
| IL230830A0 (en) | 2014-03-31 |
| AU2012293681A1 (en) | 2014-03-06 |
| EP2739723A1 (en) | 2014-06-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014527407A (ja) | 網膜変性疾患の処置方法 | |
| JP7162221B2 (ja) | 網膜組織を含む細胞凝集体及びその製造方法 | |
| Sanges et al. | Reprogramming Müller glia via in vivo cell fusion regenerates murine photoreceptors | |
| JP6651440B2 (ja) | 哺乳動物の網膜幹細胞の生産方法及び適用 | |
| TWI698242B (zh) | 利用血管母細胞產生間葉基質細胞之方法 | |
| CN110573610B (zh) | 视网膜色素上皮细胞的制备方法 | |
| JP2018518943A (ja) | 幹細胞からの筋肉系列細胞の生成 | |
| JP2025028314A (ja) | 網膜系細胞又は網膜組織の障害を伴う疾患の治療薬 | |
| TW201908478A (zh) | 調節米勒神經膠質細胞之方法 | |
| TW201636032A (zh) | 使用前驅細胞治療眼睛病況 | |
| JP2022526591A (ja) | 骨格筋幹細胞の製造及び障害の治療のための方法、組成物及びキット | |
| WO2015125941A1 (ja) | 眼疾患治療剤、そのスクリーニング方法または網膜色素上皮細胞移植に伴う拒絶反応の予測方法 | |
| TW201811344A (zh) | 使用前驅細胞治療視網膜血管性疾病 | |
| KR20180088713A (ko) | 전구 세포를 사용한 망막 변성의 치료 | |
| Ulrich | Perspectives of stem cells: From tools for studying mechanisms of neuronal differentiation towards therapy | |
| NZ621345B2 (en) | Methods of treatment of retinal degeneration diseases | |
| EP3231434A1 (en) | Method of treatment of parkinsonism | |
| TW202444894A (zh) | 視網膜組織之製造方法 | |
| WO2022009969A1 (ja) | 網膜色素上皮細胞の移植用生着促進剤 | |
| Thwaites | Methods affecting neuronal differentiation of human adult and pluripotent stem cells | |
| Jalilian | Characterization of progenitors of endothelial cells (PECs) | |
| Morad | Mesenchymal stem cells: Differentiation, hematopoietic support and possible application in cell and gene therapy for osteoarthritis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150605 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150605 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20151127 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160325 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20161028 |