JP2014523408A5 - - Google Patents
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- JP2014523408A5 JP2014523408A5 JP2014514023A JP2014514023A JP2014523408A5 JP 2014523408 A5 JP2014523408 A5 JP 2014523408A5 JP 2014514023 A JP2014514023 A JP 2014514023A JP 2014514023 A JP2014514023 A JP 2014514023A JP 2014523408 A5 JP2014523408 A5 JP 2014523408A5
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- JP
- Japan
- Prior art keywords
- seq
- antibody
- variable region
- sequence
- chain comprises
- Prior art date
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11168787 | 2011-06-06 | ||
| EP11168787.7 | 2011-06-06 | ||
| US201161505137P | 2011-07-07 | 2011-07-07 | |
| US61/505,137 | 2011-07-07 | ||
| EP12159172.1 | 2012-03-13 | ||
| EP12159172 | 2012-03-13 | ||
| PCT/EP2012/060524 WO2012168199A1 (en) | 2011-06-06 | 2012-06-04 | Therapeutic antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016237458A Division JP6416177B2 (ja) | 2011-06-06 | 2016-12-07 | 治療抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014523408A JP2014523408A (ja) | 2014-09-11 |
| JP2014523408A5 true JP2014523408A5 (enExample) | 2015-07-23 |
| JP6141834B2 JP6141834B2 (ja) | 2017-06-07 |
Family
ID=47295509
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014514023A Expired - Fee Related JP6141834B2 (ja) | 2011-06-06 | 2012-06-04 | 治療抗体 |
| JP2016237458A Expired - Fee Related JP6416177B2 (ja) | 2011-06-06 | 2016-12-07 | 治療抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016237458A Expired - Fee Related JP6416177B2 (ja) | 2011-06-06 | 2016-12-07 | 治療抗体 |
Country Status (16)
| Country | Link |
|---|---|
| US (7) | US8613926B2 (enExample) |
| EP (3) | EP2718322B1 (enExample) |
| JP (2) | JP6141834B2 (enExample) |
| KR (1) | KR101978757B1 (enExample) |
| CN (1) | CN103596982B (enExample) |
| AU (1) | AU2012266487B2 (enExample) |
| BR (1) | BR112013031198B1 (enExample) |
| CA (1) | CA2838497C (enExample) |
| DK (3) | DK2718322T3 (enExample) |
| ES (2) | ES2929575T3 (enExample) |
| IL (1) | IL229254A (enExample) |
| PL (2) | PL3424953T3 (enExample) |
| PT (1) | PT3424953T (enExample) |
| RU (1) | RU2616881C2 (enExample) |
| TW (1) | TWI564305B (enExample) |
| WO (1) | WO2012168199A1 (enExample) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2929575T3 (es) | 2011-06-06 | 2022-11-30 | Novo Nordisk As | Anticuerpos terapéuticos |
| US9657105B2 (en) * | 2013-03-15 | 2017-05-23 | City Of Hope | CD123-specific chimeric antigen receptor redirected T cells and methods of their use |
| SMT202300039T1 (it) | 2013-09-13 | 2023-03-17 | Beigene Switzerland Gmbh | Anticorpi anti-pd1 e loro uso come terapia e per diagnostica |
| CN107074957B (zh) | 2014-01-13 | 2021-05-07 | 希望之城公司 | 在Fc间隔物区中具有突变的嵌合抗原受体(CAR)及其使用方法 |
| US20170107294A1 (en) * | 2014-03-21 | 2017-04-20 | Nordlandssykehuset Hf | Anti-cd14 antibodies and uses thereof |
| TWI726608B (zh) | 2014-07-03 | 2021-05-01 | 英屬開曼群島商百濟神州有限公司 | 抗pd-l1抗體及其作為治療及診斷之用途 |
| KR102524920B1 (ko) | 2014-07-22 | 2023-04-25 | 아폴로믹스 인코포레이티드 | 항-pd-1 항체 |
| SG10201901057UA (en) | 2014-08-05 | 2019-03-28 | Cb Therapeutics Inc | Anti-pd-l1 antibodies |
| US20170328898A1 (en) * | 2014-10-31 | 2017-11-16 | Cell Trend GmbH | Diagnosis of an autoimmune disease using detection of antibodies directed against c5a-receptor |
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| US20170145086A1 (en) | 2015-11-25 | 2017-05-25 | Visterra, Inc. | Antibody molecules to april and uses thereof |
| CN106957366B (zh) * | 2016-01-12 | 2022-02-01 | 上海昀怡健康科技发展有限公司 | 一种C5aR抗体及其制备方法和应用 |
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| EA201892716A1 (ru) | 2016-06-14 | 2019-05-31 | Мерк Шарп И Доум Корп. | Антитела к фактору свертывания xi |
| WO2018007885A1 (en) | 2016-07-05 | 2018-01-11 | Beigene, Ltd. | COMBINATION OF A PD-l ANTAGONIST AND A RAF INHIBITOR FOR TREATING CANCER |
| CN110087680B (zh) | 2016-08-19 | 2024-03-19 | 百济神州有限公司 | 使用包含btk抑制剂的组合产品治疗癌症 |
| EP3573989A4 (en) | 2017-01-25 | 2020-11-18 | Beigene, Ltd. | CRYSTALLINE FORMS OF (S) -7- (1- (BUT-2-YNOYL) PIPERIDIN-4-YL) -2- (4-PHENOXYPHENYL) -4, 5, 6, 7-TETRAHY DROPYRAZOLO [1, 5-A ] PYRIMIDINE-3-CARBOXAMIDE, PREPARATION AND ASSOCIATED USES |
| AU2018235092B2 (en) | 2017-03-16 | 2024-09-19 | Innate Pharma | Compositions and methods for treating cancer |
| DK3411400T3 (da) | 2017-04-03 | 2021-10-11 | Inflarx Gmbh | Behandling af inflammatoriske sygdomme med hæmmere af c5a-aktivitet |
| MX2019013132A (es) * | 2017-05-25 | 2020-01-27 | Bristol Myers Squibb Co | Anticuerpos que comprenden regiones constantes pesadas modificadas. |
| EP3645569A4 (en) | 2017-06-26 | 2021-03-24 | BeiGene, Ltd. | IMMUNOTHERAPY FOR LIVER CELL CARCINOMA |
| US11472880B2 (en) | 2017-08-14 | 2022-10-18 | Morphosys Ag | Humanized antibodies for CD3 |
| WO2019092148A1 (en) * | 2017-11-10 | 2019-05-16 | Innate Pharma | Antibodies with functionalized glutamine residues |
| US11786529B2 (en) | 2017-11-29 | 2023-10-17 | Beigene Switzerland Gmbh | Treatment of indolent or aggressive B-cell lymphomas using a combination comprising BTK inhibitors |
| US20190300610A1 (en) | 2018-03-29 | 2019-10-03 | Hummingbird Bioscience Pte. Ltd. | Vista antigen-binding molecules |
| TWI870353B (zh) | 2018-06-18 | 2025-01-21 | 法商天賜製藥公司 | 用於治療癌症之組合物及方法 |
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| CA3121699A1 (en) * | 2018-12-05 | 2020-06-11 | Morphosys Ag | Multispecific antigen-binding molecules |
| US20220135658A1 (en) * | 2019-03-14 | 2022-05-05 | Morphosys Ag | Antibodies targeting c5ar |
| MX2022006670A (es) * | 2019-12-03 | 2023-03-17 | Shanghai Jiao Tong Univ School Of Medicine | Region fc de anticuerpo teniendo mayor afinidad de union al fcyriib. |
| TWI869528B (zh) | 2020-01-13 | 2025-01-11 | 美商威特拉公司 | C5ar1抗體分子及其用途 |
| AU2020438234A1 (en) | 2020-03-27 | 2022-09-29 | Inflarx Gmbh | Inhibitors of C5a for the treatment of corona virus infection |
| TW202208427A (zh) | 2020-05-06 | 2022-03-01 | 德商因夫萊亞斯有限公司 | 人源化抗ｃ５ａ抗體 |
| GB2595299B (en) | 2020-05-21 | 2022-08-03 | Mabsolve Ltd | Modified immunoglobulin FC regions |
| WO2022033981A1 (en) | 2020-08-12 | 2022-02-17 | Innate Pharma | Subcutaneous anti-c5ar antagonist treatment regimen with avdoralimab |
| TWI917473B (zh) | 2020-11-02 | 2026-03-11 | 新加坡商蜂鳥生物科技私人有限公司 | Bcma/taci抗原結合分子 |
| US11912781B2 (en) * | 2021-01-13 | 2024-02-27 | Visterra, Inc. | Humanized complement 5A receptor 1 antibodies and methods of use thereof |
| KR20230156921A (ko) | 2021-03-12 | 2023-11-15 | 젠맵 에이/에스 | 비-활성화 항체 변이체 |
| KR20240058149A (ko) | 2021-09-16 | 2024-05-03 | 허밍버드 바이오사이언스 피티이. 엘티디. | Vista 항원-결합 분자를 사용한 암의 치료 및 예방 |
| WO2023046979A1 (en) | 2021-09-27 | 2023-03-30 | Hummingbird Bioscience Pte. Ltd. | Treatment and prevention of cancer using vista antigen-binding molecules |
| AR127298A1 (es) | 2021-10-08 | 2024-01-10 | Genmab As | Anticuerpos que se unen a cd30 y cd3 |
| JP2024546152A (ja) * | 2021-12-16 | 2024-12-17 | 上海宝済薬業股▲ふん▼有限公司 | 免疫グロブリン分解酵素による切断に対抗するＦｃ変異体 |
| KR20250067121A (ko) | 2022-07-08 | 2025-05-14 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | Cnx 항원-결합 분자 |
| CN121293357A (zh) | 2022-08-22 | 2026-01-09 | 雅博得乐医疗公司 | Dll3结合分子及其用途 |
| EP4590706A1 (en) | 2022-09-22 | 2025-07-30 | Hummingbird Bioscience Pte. Ltd. | Treatment and prevention of cancer using vista antigen-binding molecules |
| GB202218388D0 (en) | 2022-12-07 | 2023-01-18 | Vvb Bio Pte Ltd | GP130 antigen-binding molecules |
| CN120857946A (zh) | 2023-01-03 | 2025-10-28 | 蜂鸟生物科技私人有限公司 | Her3结合抗体-药物缀合物 |
| EP4646274A1 (en) | 2023-01-06 | 2025-11-12 | Twain Therapeutics Pte. Ltd. | Antigen-binding molecules |
| CN120858116A (zh) | 2023-01-06 | 2025-10-28 | 泰温治疗私人有限公司 | 抗原结合分子 |
| US12180274B2 (en) | 2023-05-26 | 2024-12-31 | Inflarx Gmbh | Treatment of pneumonia and ARDS with inhibitors of C5a and IL-6 activity |
| GB202311050D0 (en) | 2023-07-19 | 2023-08-30 | Vvb Bio Pte Ltd | GP130 antigen-binding molecules |
| WO2025125495A1 (en) | 2023-12-13 | 2025-06-19 | Hummingbird Bioscience Pte. Ltd. | Treatment and prevention of cancer using vista antigen-binding molecules |
| WO2025133322A1 (en) | 2023-12-22 | 2025-06-26 | Agency For Science, Technology And Research | Cnx antigen-binding molecules |
| GB202405551D0 (en) | 2024-04-19 | 2024-06-05 | Vvb Bio Pte Ltd | Combination treatment |
| GB202408044D0 (en) | 2024-06-06 | 2024-07-24 | Vvb Bio Pte Ltd | gp130 antigen-binding molecules |
| WO2025257350A1 (en) | 2024-06-13 | 2025-12-18 | Singapore Health Services Pte Ltd | Pai-1 antigen-binding molecules |
| EP4670793A1 (en) | 2024-06-24 | 2025-12-31 | Montis Biosciences BV | C1Q ANTIGEN BINDING MOLECULES |
| WO2026033132A1 (en) | 2024-08-09 | 2026-02-12 | Twain Therapeutics Pte. Ltd. | Antigen-binding molecules |
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| WO2026062072A1 (en) | 2024-09-18 | 2026-03-26 | Hummingbird Bioscience Pte. Ltd. | Vista antigen-binding molecules |
| WO2026062240A1 (en) | 2024-09-20 | 2026-03-26 | Albatroz Therapeutics Pte. Ltd. | Inhibition of calnexin for the treatment of inflammatory bowel disease |
| WO2026062200A1 (en) | 2024-09-20 | 2026-03-26 | Hummingbird Bioscience Pte. Ltd. | B7-h3 antigen-binding molecules |
| WO2026063874A1 (en) | 2024-09-20 | 2026-03-26 | Hummingbird Bioscience Pte. Ltd. | B7-h3 antigen-binding molecules |
| WO2026068571A1 (en) | 2024-09-25 | 2026-04-02 | Singapore Health Services Pte. Ltd. | Lrg1 antigen-binding molecules |
| WO2026159121A1 (en) | 2025-01-22 | 2026-07-30 | VVB Bio Pte. Ltd. | Bispecific molecules |
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| ES2929575T3 (es) * | 2011-06-06 | 2022-11-30 | Novo Nordisk As | Anticuerpos terapéuticos |
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-
2012
- 2012-06-04 ES ES20187662T patent/ES2929575T3/es active Active
- 2012-06-04 DK DK12725447.2T patent/DK2718322T3/en active
- 2012-06-04 EP EP12725447.2A patent/EP2718322B1/en active Active
- 2012-06-04 CA CA2838497A patent/CA2838497C/en active Active
- 2012-06-04 AU AU2012266487A patent/AU2012266487B2/en not_active Ceased
- 2012-06-04 DK DK20187662.0T patent/DK3798230T3/da active
- 2012-06-04 DK DK18175085.2T patent/DK3424953T3/da active
- 2012-06-04 PL PL18175085T patent/PL3424953T3/pl unknown
- 2012-06-04 EP EP18175085.2A patent/EP3424953B1/en active Active
- 2012-06-04 PL PL12725447T patent/PL2718322T3/pl unknown
- 2012-06-04 RU RU2013155029A patent/RU2616881C2/ru active
- 2012-06-04 BR BR112013031198-3A patent/BR112013031198B1/pt not_active IP Right Cessation
- 2012-06-04 EP EP20187662.0A patent/EP3798230B1/en active Active
- 2012-06-04 WO PCT/EP2012/060524 patent/WO2012168199A1/en not_active Ceased
- 2012-06-04 JP JP2014514023A patent/JP6141834B2/ja not_active Expired - Fee Related
- 2012-06-04 CN CN201280028064.1A patent/CN103596982B/zh not_active Expired - Fee Related
- 2012-06-04 PT PT181750852T patent/PT3424953T/pt unknown
- 2012-06-04 ES ES12725447.2T patent/ES2693647T3/es active Active
- 2012-06-04 KR KR1020137034239A patent/KR101978757B1/ko not_active Expired - Fee Related
- 2012-06-06 TW TW101120198A patent/TWI564305B/zh active
- 2012-06-06 US US13/490,093 patent/US8613926B2/en not_active Expired - Fee Related
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2013
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2014
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2016
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2019
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2020
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2023
- 2023-12-11 US US18/536,032 patent/US20240218076A1/en not_active Abandoned
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