JP2014523408A5 - - Google Patents
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- JP2014523408A5 JP2014523408A5 JP2014514023A JP2014514023A JP2014523408A5 JP 2014523408 A5 JP2014523408 A5 JP 2014523408A5 JP 2014514023 A JP2014514023 A JP 2014514023A JP 2014514023 A JP2014514023 A JP 2014514023A JP 2014523408 A5 JP2014523408 A5 JP 2014523408A5
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- JP
- Japan
- Prior art keywords
- seq
- antibody
- variable region
- sequence
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11168787.7 | 2011-06-06 | ||
| EP11168787 | 2011-06-06 | ||
| US201161505137P | 2011-07-07 | 2011-07-07 | |
| US61/505,137 | 2011-07-07 | ||
| EP12159172 | 2012-03-13 | ||
| EP12159172.1 | 2012-03-13 | ||
| PCT/EP2012/060524 WO2012168199A1 (en) | 2011-06-06 | 2012-06-04 | Therapeutic antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016237458A Division JP6416177B2 (ja) | 2011-06-06 | 2016-12-07 | 治療抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014523408A JP2014523408A (ja) | 2014-09-11 |
| JP2014523408A5 true JP2014523408A5 (enExample) | 2015-07-23 |
| JP6141834B2 JP6141834B2 (ja) | 2017-06-07 |
Family
ID=47295509
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014514023A Expired - Fee Related JP6141834B2 (ja) | 2011-06-06 | 2012-06-04 | 治療抗体 |
| JP2016237458A Active JP6416177B2 (ja) | 2011-06-06 | 2016-12-07 | 治療抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016237458A Active JP6416177B2 (ja) | 2011-06-06 | 2016-12-07 | 治療抗体 |
Country Status (16)
| Country | Link |
|---|---|
| US (7) | US8613926B2 (enExample) |
| EP (3) | EP2718322B1 (enExample) |
| JP (2) | JP6141834B2 (enExample) |
| KR (1) | KR101978757B1 (enExample) |
| CN (1) | CN103596982B (enExample) |
| AU (1) | AU2012266487B2 (enExample) |
| BR (1) | BR112013031198B1 (enExample) |
| CA (1) | CA2838497C (enExample) |
| DK (3) | DK2718322T3 (enExample) |
| ES (2) | ES2929575T3 (enExample) |
| IL (1) | IL229254A (enExample) |
| PL (2) | PL2718322T3 (enExample) |
| PT (1) | PT3424953T (enExample) |
| RU (1) | RU2616881C2 (enExample) |
| TW (1) | TWI564305B (enExample) |
| WO (1) | WO2012168199A1 (enExample) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2718322T3 (pl) * | 2011-06-06 | 2019-07-31 | Novo Nordisk A/S | Lecznicze przeciwciała |
| US9657105B2 (en) * | 2013-03-15 | 2017-05-23 | City Of Hope | CD123-specific chimeric antigen receptor redirected T cells and methods of their use |
| LT3702373T (lt) | 2013-09-13 | 2022-11-10 | Beigene Switzerland Gmbh | Anti-pd1 antikūnai ir jų naudojimas terapijai ir diagnostikai |
| US20160333108A1 (en) * | 2014-01-13 | 2016-11-17 | Stephen J. Forman | CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE |
| US20170107294A1 (en) * | 2014-03-21 | 2017-04-20 | Nordlandssykehuset Hf | Anti-cd14 antibodies and uses thereof |
| TWI726608B (zh) | 2014-07-03 | 2021-05-01 | 英屬開曼群島商百濟神州有限公司 | 抗pd-l1抗體及其作為治療及診斷之用途 |
| MX388181B (es) | 2014-07-22 | 2025-03-19 | Cb Therapeutics Inc | Anticuerpos anti-pd-1. |
| JP6909153B2 (ja) | 2014-08-05 | 2021-07-28 | アポロミクス インコーポレイテッド | 抗ｐｄ−ｌ１抗体 |
| US20170328898A1 (en) * | 2014-10-31 | 2017-11-16 | Cell Trend GmbH | Diagnosis of an autoimmune disease using detection of antibodies directed against c5a-receptor |
| CN108779174B (zh) * | 2015-11-04 | 2022-11-29 | 希望之城公司 | 靶向her2的嵌合抗原受体 |
| JP2019509014A (ja) * | 2015-11-23 | 2019-04-04 | イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． | Ｃｄ３９血管アイソフォームターゲティング剤 |
| DK3380522T5 (da) | 2015-11-25 | 2024-09-30 | Visterra Inc | Antistofmolekyler til april og anvendelser deraf |
| CN106957366B (zh) * | 2016-01-12 | 2022-02-01 | 上海昀怡健康科技发展有限公司 | 一种C5aR抗体及其制备方法和应用 |
| RU2021129189A (ru) | 2016-01-22 | 2021-11-15 | Мерк Шарп И Доум Корп. | Антитела против фактора свертывания xi |
| MY201852A (en) | 2016-06-14 | 2024-03-20 | Merck Sharp & Dohme Llc | Anti-coagulation factor xi antibodies |
| WO2018007885A1 (en) | 2016-07-05 | 2018-01-11 | Beigene, Ltd. | COMBINATION OF A PD-l ANTAGONIST AND A RAF INHIBITOR FOR TREATING CANCER |
| AU2017313085B2 (en) | 2016-08-19 | 2024-06-20 | Beone Medicines I Gmbh | Use of a combination comprising a Btk inhibitor for treating cancers |
| WO2018137681A1 (en) | 2017-01-25 | 2018-08-02 | Beigene, Ltd. | Crystalline forms of (s) -7- (1- (but-2-ynoyl) piperidin-4-yl) -2- (4-phenoxyphenyl) -4, 5, 6, 7-tetrahy dropyrazolo [1, 5-a] pyrimidine-3-carboxamide, preparation, and uses thereof |
| CN110382544B (zh) | 2017-03-16 | 2023-12-22 | 先天制药公司 | 用于治疗癌症的组合物和方法 |
| EP3978523A1 (en) | 2017-04-03 | 2022-04-06 | InflaRx GmbH | Treatment of inflammatory diseases with inhibitors of c5a activity |
| US20200299400A1 (en) * | 2017-05-25 | 2020-09-24 | Bristol-Myers Squibb Company | Antibodies comprising modified heavy constant regions |
| KR102757960B1 (ko) | 2017-06-26 | 2025-01-22 | 베이진 엘티디 | 간세포암(hepatocellular carcinoma: HCC)에 대한 면역 치료 |
| US11472880B2 (en) | 2017-08-14 | 2022-10-18 | Morphosys Ag | Humanized antibodies for CD3 |
| WO2019092148A1 (en) * | 2017-11-10 | 2019-05-16 | Innate Pharma | Antibodies with functionalized glutamine residues |
| CN111801334B (zh) | 2017-11-29 | 2023-06-09 | 百济神州瑞士有限责任公司 | 使用包含btk抑制剂的组合治疗惰性或侵袭性b-细胞淋巴瘤 |
| US20190300610A1 (en) | 2018-03-29 | 2019-10-03 | Hummingbird Bioscience Pte. Ltd. | Vista antigen-binding molecules |
| AU2019289646B2 (en) | 2018-06-18 | 2025-10-23 | Innate Pharma | Compositions and methods for treating cancer |
| EA202190647A1 (ru) | 2018-09-17 | 2021-09-09 | Абкуро, Инк. | Антитела к klrg1 |
| CA3121699A1 (en) * | 2018-12-05 | 2020-06-11 | Morphosys Ag | Multispecific antigen-binding molecules |
| EP3938393A1 (en) | 2019-03-14 | 2022-01-19 | MorphoSys AG | Antibodies targeting c5ar |
| EP4071167A4 (en) * | 2019-12-03 | 2024-03-06 | Shanghai Jiao Tong University School of Medicine | ANTIBODIES FC REGION WITH INCREASED FCGRIB AFFINITY |
| TWI869528B (zh) | 2020-01-13 | 2025-01-11 | 美商威特拉公司 | C5ar1抗體分子及其用途 |
| TW202208427A (zh) | 2020-05-06 | 2022-03-01 | 德商因夫萊亞斯有限公司 | 人源化抗ｃ５ａ抗體 |
| GB2595299B (en) * | 2020-05-21 | 2022-08-03 | Mabsolve Ltd | Modified immunoglobulin FC regions |
| US20230340140A1 (en) | 2020-08-12 | 2023-10-26 | Innate Pharma | Subcutaneous anti-c5ar antagonist treatment regimen with avdoralimab |
| WO2022090556A1 (en) | 2020-11-02 | 2022-05-05 | Hummingbird Bioscience Pte. Ltd. | Bcma/taci antigen-binding molecules |
| CN120309734A (zh) | 2021-01-13 | 2025-07-15 | 威特拉公司 | 人源化补体5a受体1抗体和其使用方法 |
| WO2022189667A1 (en) | 2021-03-12 | 2022-09-15 | Genmab A/S | Non-activating antibody variants |
| JP2024535053A (ja) | 2021-09-16 | 2024-09-26 | ハミングバード・バイオサイエンス・プライベート・リミテッド | Ｖｉｓｔａ抗原結合性分子を使用する、がんの処置および防止 |
| WO2023046979A1 (en) | 2021-09-27 | 2023-03-30 | Hummingbird Bioscience Pte. Ltd. | Treatment and prevention of cancer using vista antigen-binding molecules |
| AR127298A1 (es) * | 2021-10-08 | 2024-01-10 | Genmab As | Anticuerpos que se unen a cd30 y cd3 |
| EP4450081A4 (en) * | 2021-12-16 | 2025-05-07 | Shanghai Bao Pharmaceuticals Co., Ltd. | Anti-immunoglobulin-degrading enzyme-fermented FC variant |
| TW202409280A (zh) | 2022-07-08 | 2024-03-01 | 新加坡科技研究局 | Cnx抗原結合分子 |
| CN121293357A (zh) | 2022-08-22 | 2026-01-09 | 雅博得乐医疗公司 | Dll3结合分子及其用途 |
| US20260098093A1 (en) | 2022-09-22 | 2026-04-09 | Hummingbird Bioscience Pte. Ltd. | Treatment and prevention of cancer using vista antigen-binding molecules |
| GB202218388D0 (en) | 2022-12-07 | 2023-01-18 | Vvb Bio Pte Ltd | GP130 antigen-binding molecules |
| US20240238439A1 (en) | 2023-01-03 | 2024-07-18 | Hummingbird Bioscience Pte. Ltd. | Her3-binding antibody-drug conjugate |
| CN121002069A (zh) | 2023-01-06 | 2025-11-21 | 泰温治疗私人有限公司 | 抗原结合分子 |
| EP4646439A1 (en) | 2023-01-06 | 2025-11-12 | Twain Therapeutics Pte. Ltd. | Antigen-binding molecules |
| US12180274B2 (en) | 2023-05-26 | 2024-12-31 | Inflarx Gmbh | Treatment of pneumonia and ARDS with inhibitors of C5a and IL-6 activity |
| GB202311050D0 (en) | 2023-07-19 | 2023-08-30 | Vvb Bio Pte Ltd | GP130 antigen-binding molecules |
| WO2025125495A1 (en) | 2023-12-13 | 2025-06-19 | Hummingbird Bioscience Pte. Ltd. | Treatment and prevention of cancer using vista antigen-binding molecules |
| WO2025133322A1 (en) | 2023-12-22 | 2025-06-26 | Agency For Science, Technology And Research | Cnx antigen-binding molecules |
| GB202405551D0 (en) | 2024-04-19 | 2024-06-05 | Vvb Bio Pte Ltd | Combination treatment |
| GB202408044D0 (en) | 2024-06-06 | 2024-07-24 | Vvb Bio Pte Ltd | gp130 antigen-binding molecules |
| WO2025257350A1 (en) | 2024-06-13 | 2025-12-18 | Singapore Health Services Pte Ltd | Pai-1 antigen-binding molecules |
| EP4670793A1 (en) | 2024-06-24 | 2025-12-31 | Montis Biosciences BV | C1Q ANTIGEN BINDING MOLECULES |
| WO2026033139A1 (en) | 2024-08-09 | 2026-02-12 | Twain Therapeutics Pte. Ltd. | Antigen-binding molecules |
| WO2026033132A1 (en) | 2024-08-09 | 2026-02-12 | Twain Therapeutics Pte. Ltd. | Antigen-binding molecules |
| WO2026033134A1 (en) | 2024-08-09 | 2026-02-12 | Twain Therapeutics Pte. Ltd. | Antigen-binding molecules |
| WO2026062072A1 (en) | 2024-09-18 | 2026-03-26 | Hummingbird Bioscience Pte. Ltd. | Vista antigen-binding molecules |
| WO2026063874A1 (en) | 2024-09-20 | 2026-03-26 | Hummingbird Bioscience Pte. Ltd. | B7-h3 antigen-binding molecules |
| WO2026062200A1 (en) | 2024-09-20 | 2026-03-26 | Hummingbird Bioscience Pte. Ltd. | B7-h3 antigen-binding molecules |
| WO2026062240A1 (en) | 2024-09-20 | 2026-03-26 | Albatroz Therapeutics Pte. Ltd. | Inhibition of calnexin for the treatment of inflammatory bowel disease |
| WO2026068570A1 (en) | 2024-09-25 | 2026-04-02 | Singapore Health Services Pte. Ltd. | Lrg1 antigen-binding molecules |
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-
2012
- 2012-06-04 PL PL12725447T patent/PL2718322T3/pl unknown
- 2012-06-04 ES ES20187662T patent/ES2929575T3/es active Active
- 2012-06-04 WO PCT/EP2012/060524 patent/WO2012168199A1/en not_active Ceased
- 2012-06-04 BR BR112013031198-3A patent/BR112013031198B1/pt not_active IP Right Cessation
- 2012-06-04 DK DK12725447.2T patent/DK2718322T3/en active
- 2012-06-04 CA CA2838497A patent/CA2838497C/en active Active
- 2012-06-04 PT PT181750852T patent/PT3424953T/pt unknown
- 2012-06-04 AU AU2012266487A patent/AU2012266487B2/en not_active Ceased
- 2012-06-04 DK DK18175085.2T patent/DK3424953T3/da active
- 2012-06-04 DK DK20187662.0T patent/DK3798230T3/da active
- 2012-06-04 EP EP12725447.2A patent/EP2718322B1/en active Active
- 2012-06-04 ES ES12725447.2T patent/ES2693647T3/es active Active
- 2012-06-04 RU RU2013155029A patent/RU2616881C2/ru active
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- 2012-06-04 CN CN201280028064.1A patent/CN103596982B/zh active Active
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- 2012-06-06 US US13/490,093 patent/US8613926B2/en not_active Expired - Fee Related
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2013
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2014
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2016
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2023
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