JP2014520551A5 - - Google Patents
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- Publication number
- JP2014520551A5 JP2014520551A5 JP2014520269A JP2014520269A JP2014520551A5 JP 2014520551 A5 JP2014520551 A5 JP 2014520551A5 JP 2014520269 A JP2014520269 A JP 2014520269A JP 2014520269 A JP2014520269 A JP 2014520269A JP 2014520551 A5 JP2014520551 A5 JP 2014520551A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- nucleic acid
- cell
- culturing
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161506314P | 2011-07-11 | 2011-07-11 | |
| US61/506,314 | 2011-07-11 | ||
| PCT/US2012/046194 WO2013009825A1 (en) | 2011-07-11 | 2012-07-11 | Methods for cell reprogramming and genome engineering |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014520551A JP2014520551A (ja) | 2014-08-25 |
| JP2014520551A5 true JP2014520551A5 (enExample) | 2015-08-13 |
Family
ID=46516887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014520269A Pending JP2014520551A (ja) | 2011-07-11 | 2012-07-11 | 細胞のリプログラミング方法およびゲノムの改変方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20130040302A1 (enExample) |
| EP (1) | EP2732029B1 (enExample) |
| JP (1) | JP2014520551A (enExample) |
| CA (1) | CA2841165A1 (enExample) |
| WO (1) | WO2013009825A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3260140B1 (en) | 2011-12-05 | 2021-02-03 | Factor Bioscience Inc. | Methods and products for transfecting cells |
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| CA2890110C (en) | 2012-11-01 | 2023-05-02 | Factor Bioscience Inc. | Methods and products for expressing proteins in cells |
| AU2014233465A1 (en) * | 2013-03-15 | 2015-09-03 | Cibus Europe B.V. | Targeted gene modification using oligonucleotide-mediated gene repair |
| EP2792742A1 (en) | 2013-04-17 | 2014-10-22 | Universitätsklinikum Hamburg-Eppendorf (UKE) | Gene-therapy vectors for treating cardiomyopathy |
| US10738323B2 (en) * | 2013-07-12 | 2020-08-11 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
| KR101655383B1 (ko) * | 2013-07-27 | 2016-09-08 | 고려대학교 산학협력단 | 소분자 화합물을 포함하는 만능성 줄기세포의 염색체 안정성 유지용 조성물 |
| KR102415811B1 (ko) | 2014-01-31 | 2022-07-04 | 팩터 바이오사이언스 인크. | 핵산 제조 및 송달을 위한 방법 및 산물 |
| CN105039399A (zh) * | 2014-04-23 | 2015-11-11 | 复旦大学 | 多能干细胞-遗传性心肌病心肌细胞及其制备方法 |
| US10626372B1 (en) | 2015-01-26 | 2020-04-21 | Fate Therapeutics, Inc. | Methods and compositions for inducing hematopoietic cell differentiation |
| US11241505B2 (en) | 2015-02-13 | 2022-02-08 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| US12642852B1 (en) | 2015-11-04 | 2026-06-02 | Fate Therapeutics, Inc. | Genomic engineering of pluripotent cells |
| CN122146606A (zh) | 2015-11-04 | 2026-06-05 | 菲特治疗公司 | 用于诱导造血细胞分化的方法和组合物 |
| CA3010764A1 (en) * | 2016-01-12 | 2017-07-20 | Lonza Walkersville, Inc. | Methods and vectors to produce vector free induced pluripotent stem cells |
| WO2017196175A1 (en) | 2016-05-12 | 2017-11-16 | Erasmus University Medical Center Rotterdam | A method for culturing myogenic cells, cultures obtained therefrom, screening methods, and cell culture medium. |
| US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US11572545B2 (en) | 2016-06-16 | 2023-02-07 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| IL264439B2 (en) | 2016-08-17 | 2024-08-01 | Factor Bioscience Inc | non-viral, cell-free composition comprising a synthetic messenger RNA (MRNA) encoding a gene-editing protein for use in treating cancer, and a synthetic RNA encoding a gene-editing protein for use in treatment |
| US20190390221A1 (en) * | 2016-11-02 | 2019-12-26 | David Kiewlich | Plasmid vectors for expression of large nucleic acid transgenes |
| CN110891967B (zh) * | 2017-04-18 | 2025-03-14 | 富士胶片细胞动力公司 | 抗原特异性免疫效应细胞 |
| NL2019517B1 (en) | 2017-09-08 | 2019-03-19 | Univ Erasmus Med Ct Rotterdam | New therapy for Pompe disease |
| CN111511902A (zh) * | 2017-12-28 | 2020-08-07 | J·大卫格莱斯顿研究所-根据J·大卫格莱斯顿遗嘱的遗嘱信托 | 通过crispr激活生成诱导性多能细胞 |
| EP3747991A4 (en) * | 2018-01-29 | 2022-01-19 | Institute Of Zoology, Chinese Academy Of Sciences | METHOD OF INDUCING CELLS |
| CN110016483A (zh) * | 2019-04-18 | 2019-07-16 | 安徽农业大学 | 一种研究卵母细胞体外成熟中卵丘细胞基因功能的方法 |
| CA3145425A1 (en) | 2019-07-03 | 2021-01-07 | Factor Bioscience Inc. | Cationic lipids and uses thereof |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| FI4103214T3 (fi) | 2020-02-13 | 2026-07-03 | Tenaya Therapeutics Inc | Geeniterapian vektorit sydänsairauden hoitoon |
| EP3922431A1 (en) | 2020-06-08 | 2021-12-15 | Erasmus University Medical Center Rotterdam | Method of manufacturing microdevices for lab-on-chip applications |
| CN113201481B (zh) * | 2021-04-19 | 2023-10-13 | 清华大学深圳国际研究生院 | 皮肤微球及其制备方法和应用 |
| GB202115676D0 (en) * | 2021-11-01 | 2021-12-15 | Icahn School Med Mount Sinai | Methods and compositions for bat ipsc preparation and use |
| WO2024091801A2 (en) * | 2022-10-13 | 2024-05-02 | President And Fellows Of Harvard College | Methods and compositions for inducing cell differentiation |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1088100A (en) | 1913-04-08 | 1914-02-24 | Benjamin P Saunders | Apparatus for unloading freight-cars. |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| EP0273085A1 (en) | 1986-12-29 | 1988-07-06 | IntraCel Corporation | A method for internalizing nucleic acids into eukaryotic cells |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5302523A (en) | 1989-06-21 | 1994-04-12 | Zeneca Limited | Transformation of plant cells |
| US5550318A (en) | 1990-04-17 | 1996-08-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
| US7705215B1 (en) | 1990-04-17 | 2010-04-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
| US5322783A (en) | 1989-10-17 | 1994-06-21 | Pioneer Hi-Bred International, Inc. | Soybean transformation by microparticle bombardment |
| US5484956A (en) | 1990-01-22 | 1996-01-16 | Dekalb Genetics Corporation | Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin |
| US5384253A (en) | 1990-12-28 | 1995-01-24 | Dekalb Genetics Corporation | Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes |
| WO1993004169A1 (en) | 1991-08-20 | 1993-03-04 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
| ES2148179T3 (es) | 1991-09-06 | 2000-10-16 | Yoshitomi Pharmaceutical | Compuesto de 4-amino(alquil)ciclohexan-1-carboxamida y uso del mismo. |
| US5610042A (en) | 1991-10-07 | 1997-03-11 | Ciba-Geigy Corporation | Methods for stable transformation of wheat |
| JP4115514B2 (ja) | 1991-10-23 | 2008-07-09 | キャンサー・リサーチ・キヤンペーン・テクノロジー・リミテツド | Cb 1954およびその類似体を細胞障害性の形態に還元するための細菌のニトロリダクターゼ |
| US5702932A (en) | 1992-07-20 | 1997-12-30 | University Of Florida | Microinjection methods to transform arthropods with exogenous DNA |
| AU670316B2 (en) | 1992-07-27 | 1996-07-11 | Pioneer Hi-Bred International, Inc. | An improved method of (agrobacterium)-mediated transformation of cultured soybean cells |
| DE4228457A1 (de) | 1992-08-27 | 1994-04-28 | Beiersdorf Ag | Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen |
| GB9222888D0 (en) | 1992-10-30 | 1992-12-16 | British Tech Group | Tomography |
| US6033907A (en) | 1995-09-29 | 2000-03-07 | Indiana University Foundation | Enhanced virus-mediated DNA transfer |
| US5686278A (en) | 1994-03-25 | 1997-11-11 | Indiana University Foundation | Methods for enhanced retrovirus-mediated gene transfer |
| US7083979B1 (en) | 1994-03-25 | 2006-08-01 | Indiana University Foundation | Methods for enhanced retroviral-mediated gene transfer |
| US5656610A (en) | 1994-06-21 | 1997-08-12 | University Of Southern California | Producing a protein in a mammal by injection of a DNA-sequence into the tongue |
| FR2722208B1 (fr) | 1994-07-05 | 1996-10-04 | Inst Nat Sante Rech Med | Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique |
| US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| KR100793625B1 (ko) | 1995-09-29 | 2008-01-11 | 인디아나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 바이러스-매개된 dna 전달을 향상시키는 방법에 의해생산된 생존성 세포 집단 및 이를 포함하는 세포 조성물 |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US5780448A (en) | 1995-11-07 | 1998-07-14 | Ottawa Civic Hospital Loeb Research | DNA-based vaccination of fish |
| US20030059913A1 (en) | 1995-11-20 | 2003-03-27 | Walter Weyler | Novel Microorganisms with ability to degrade indole and novel enzymes therefrom |
| US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
| US5945100A (en) | 1996-07-31 | 1999-08-31 | Fbp Corporation | Tumor delivery vehicles |
| US5981274A (en) | 1996-09-18 | 1999-11-09 | Tyrrell; D. Lorne J. | Recombinant hepatitis virus vectors |
| JP2001508302A (ja) | 1997-01-10 | 2001-06-26 | ライフ テクノロジーズ,インコーポレイテッド | 胚性幹細胞血清置換 |
| US5994624A (en) | 1997-10-20 | 1999-11-30 | Cotton Incorporated | In planta method for the production of transgenic plants |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| GB0002261D0 (en) | 2000-02-02 | 2000-03-22 | Amersham Pharm Biotech Uk Ltd | Fluorescent detection method & reagent |
| JP4458222B2 (ja) | 2000-05-16 | 2010-04-28 | 独立行政法人理化学研究所 | 胚性幹細胞の外胚葉系細胞への新規な分化誘導法及びその用途 |
| EP1287116A2 (en) | 2000-05-17 | 2003-03-05 | Geron Corporation | Neural progenitor cell populations |
| JP2002184539A (ja) | 2000-12-14 | 2002-06-28 | Auto Network Gijutsu Kenkyusho:Kk | コネクタ |
| PE20020958A1 (es) | 2001-03-23 | 2002-11-14 | Bayer Corp | Inhibidores de la rho-quinasa |
| HN2002000067A (es) | 2001-03-23 | 2003-10-24 | Bayer Healthcare Llc | Inhibidores de la rho - quinasa. |
| US20030211603A1 (en) | 2001-08-14 | 2003-11-13 | Earp David J. | Reprogramming cells for enhanced differentiation capacity using pluripotent stem cells |
| JP2003097552A (ja) | 2001-09-21 | 2003-04-03 | Nsk Ltd | 摩擦付加装置および直動案内装置 |
| US20030062225A1 (en) | 2001-10-03 | 2003-04-03 | Stucky Paul A. | Elevator load bearing assembly having a detectable element that is indicative of local strain |
| EP1465900B1 (en) | 2002-01-10 | 2008-05-14 | Bayer HealthCare AG | Rho-kinase inhibitors |
| CA2473910C (en) | 2002-01-23 | 2011-03-15 | Bayer Pharmaceuticals Corporation | Pyrimidine derivatives as rho-kinase inhibitors |
| MXPA04007191A (es) | 2002-01-23 | 2005-03-31 | Bayer Pharmaceuticals Corp | Derivados de pirimidina como inhibidores de rho-quinasa. |
| DE10224242A1 (de) | 2002-05-29 | 2003-12-11 | Max Delbrueck Centrum | Frog Prince, ein Transposonvektor für den Gentransfer bei Wirbeltieren |
| US20040039796A1 (en) | 2002-08-08 | 2004-02-26 | Virtual Radio, Inc. | Personalized cyber disk jockey and Internet radio advertising |
| JP2004295625A (ja) | 2003-03-27 | 2004-10-21 | Fujitsu Ltd | エリア情報提供システム、エリア情報提供プログラム |
| US20050123902A1 (en) | 2003-05-21 | 2005-06-09 | President And Fellows Of Harvard College | Human papillomavirus inhibitors |
| WO2005080554A1 (ja) | 2004-02-23 | 2005-09-01 | Kyoto University | 胚性幹細胞の分化調節方法 |
| BRPI0514641A (pt) | 2004-09-08 | 2008-06-17 | Wisconsin Alumni Res Found | cultivação das células tronco embriÈnica humana |
| US20070116680A1 (en) | 2005-11-18 | 2007-05-24 | Rensselaer Polytechnic Institute | Stem cells within gel microenvironments |
| WO2007113505A2 (en) | 2006-03-30 | 2007-10-11 | The University Court Of The University Of Edinburgh | Culture medium containing kinase inhibitors. and uses thereof |
| WO2008005268A1 (en) | 2006-06-30 | 2008-01-10 | Schering Corporation | Substituted piperidines that increase p53 activity and the uses thereof |
| CA2657227A1 (en) | 2006-07-14 | 2008-01-17 | Novartis Ag | Pyrimidine derivatives as alk-5 inhibitors |
| SE0950586L (sv) | 2007-01-17 | 2009-08-13 | Wisconsin Alumni Res Found | Förbättrad odling av stamceller |
| EP2126045A4 (en) | 2007-01-30 | 2010-05-26 | Univ Georgia | EARLY MESODERM CELLS, STABLE POPULATION OF MESENDODERM CELLS WITH THE ABILITY TO GENERATE ENDODERM AND MESODERM CELL LINES AND MULTIPOTENTIAL MIGRATION CELLS |
| EP2268796A1 (en) * | 2008-03-17 | 2011-01-05 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Vectors and methods for generating vector-free induced pluripotent stem (ips) cells using site-specific recombination |
| ES2587395T3 (es) * | 2008-06-04 | 2016-10-24 | Cellular Dynamics International, Inc. | Procedimientos para la producción de células IPS usando un enfoque no vírico |
| JP2011525794A (ja) * | 2008-06-26 | 2011-09-29 | 国立大学法人大阪大学 | iPS細胞の製造方法および製造キット |
| WO2010042490A1 (en) * | 2008-10-06 | 2010-04-15 | Boston Medical Center Corporation | A single lentiviral vector system for induced pluripotent (ips) stem cells derivation |
| EP3450545B1 (en) * | 2008-10-24 | 2023-08-23 | Wisconsin Alumni Research Foundation | Pluripotent stem cells obtained by non-viral reprogramming |
| KR101775926B1 (ko) * | 2009-11-04 | 2017-09-07 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 화학 물질을 이용한 에피솜 재프로그래밍 |
| EP2601289B1 (en) * | 2010-08-04 | 2017-07-12 | Cellular Dynamics International, Inc. | Reprogramming immortalized b cells |
-
2012
- 2012-07-11 WO PCT/US2012/046194 patent/WO2013009825A1/en not_active Ceased
- 2012-07-11 CA CA2841165A patent/CA2841165A1/en not_active Abandoned
- 2012-07-11 US US13/546,365 patent/US20130040302A1/en not_active Abandoned
- 2012-07-11 JP JP2014520269A patent/JP2014520551A/ja active Pending
- 2012-07-11 EP EP12736042.8A patent/EP2732029B1/en active Active
-
2016
- 2016-02-23 US US15/051,541 patent/US20160281063A1/en not_active Abandoned
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