JP2014509189A - 結腸ガン遺伝子発現シグネチャーおよび使用方法 - Google Patents

結腸ガン遺伝子発現シグネチャーおよび使用方法 Download PDF

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JP2014509189A
JP2014509189A JP2013551314A JP2013551314A JP2014509189A JP 2014509189 A JP2014509189 A JP 2014509189A JP 2013551314 A JP2013551314 A JP 2013551314A JP 2013551314 A JP2013551314 A JP 2013551314A JP 2014509189 A JP2014509189 A JP 2014509189A
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colon cancer
nucleic acid
transcripts
sample
expression level
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JP2014509189A5 (enExample
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デニス ポール ハーキン、
ヴィターリ プロウスキー、
ジュリー ブラック、
ペーター カー、
リチャード ケネディ、
アンドレアス ヴィンター、
ティモシー デイヴィソン、
マックス バイレスジョ、
ヴァディム ファルツディノフ、
クレア ウィルソン、
ロバート ジェームス ホルト、
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アルマック ダイアグノスティックス リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/57535—
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
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  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013551314A 2011-01-25 2012-01-25 結腸ガン遺伝子発現シグネチャーおよび使用方法 Pending JP2014509189A (ja)

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US201161435922P 2011-01-25 2011-01-25
US61/435,922 2011-01-25
PCT/US2012/022594 WO2012103250A2 (en) 2011-01-25 2012-01-25 Colon cancer gene expression signatures and methods of use

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JP2014509189A true JP2014509189A (ja) 2014-04-17
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US (1) US10196691B2 (enExample)
EP (1) EP2668296B1 (enExample)
JP (1) JP2014509189A (enExample)
KR (1) KR20140006898A (enExample)
CN (1) CN103403543B9 (enExample)
AU (1) AU2012209074A1 (enExample)
BR (1) BR112013018924A2 (enExample)
CA (1) CA2825218A1 (enExample)
EA (1) EA201391074A1 (enExample)
IL (1) IL227643A0 (enExample)
MX (1) MX2013008367A (enExample)
SG (1) SG192108A1 (enExample)
WO (1) WO2012103250A2 (enExample)
ZA (1) ZA201305024B (enExample)

Cited By (1)

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JP2023531305A (ja) * 2020-06-30 2023-07-21 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 術前補助療法後の固形癌患者の再発及び／又は死亡のリスクを予測するための方法。

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CN111321220A (zh) * 2018-12-14 2020-06-23 中国医学科学院肿瘤医院 用于检测直肠癌放化疗敏感性的组合物、微阵列和计算机系统
CN110079607B (zh) * 2019-04-04 2022-08-02 陕西师范大学 一种引物组、检测血液样品种属的方法及应用
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CN111951883A (zh) * 2020-08-04 2020-11-17 广东省第二人民医院（广东省卫生应急医院） 一种特征mRNA表达谱组合及结肠癌早期预测方法
CN115786518A (zh) * 2022-11-29 2023-03-14 广东医科大学附属医院 嗅素结构域家族蛋白4（olfm4）在结肠癌检测产品中的应用
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MX2013008367A (es) 2013-08-12
WO2012103250A3 (en) 2012-10-11
SG192108A1 (en) 2013-08-30
US20140094379A1 (en) 2014-04-03
WO2012103250A2 (en) 2012-08-02
EP2668296A2 (en) 2013-12-04
EP2668296B1 (en) 2018-08-15
EA201391074A1 (ru) 2013-12-30
CN103403543B9 (zh) 2017-05-17
CA2825218A1 (en) 2012-08-02
KR20140006898A (ko) 2014-01-16
BR112013018924A2 (en) 2018-05-08
AU2012209074A1 (en) 2013-07-11
ZA201305024B (en) 2014-03-26
IL227643A0 (en) 2013-09-30
CN103403543B (zh) 2016-11-09
EP2668296A4 (en) 2015-09-02
CN103403543A (zh) 2013-11-20
NZ612471A (en) 2015-11-27
US10196691B2 (en) 2019-02-05

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