MX2013008367A - Firmas de esxpresion genetica de cancer de colon y metodos de uso. - Google Patents
Firmas de esxpresion genetica de cancer de colon y metodos de uso.Info
- Publication number
- MX2013008367A MX2013008367A MX2013008367A MX2013008367A MX2013008367A MX 2013008367 A MX2013008367 A MX 2013008367A MX 2013008367 A MX2013008367 A MX 2013008367A MX 2013008367 A MX2013008367 A MX 2013008367A MX 2013008367 A MX2013008367 A MX 2013008367A
- Authority
- MX
- Mexico
- Prior art keywords
- colon cancer
- methods
- gene expression
- cancer gene
- expression signatures
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G01N33/57535—
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161435922P | 2011-01-25 | 2011-01-25 | |
| PCT/US2012/022594 WO2012103250A2 (en) | 2011-01-25 | 2012-01-25 | Colon cancer gene expression signatures and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2013008367A true MX2013008367A (es) | 2013-08-12 |
Family
ID=46581385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013008367A MX2013008367A (es) | 2011-01-25 | 2012-01-25 | Firmas de esxpresion genetica de cancer de colon y metodos de uso. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10196691B2 (enExample) |
| EP (1) | EP2668296B1 (enExample) |
| JP (1) | JP2014509189A (enExample) |
| KR (1) | KR20140006898A (enExample) |
| CN (1) | CN103403543B9 (enExample) |
| AU (1) | AU2012209074A1 (enExample) |
| BR (1) | BR112013018924A2 (enExample) |
| CA (1) | CA2825218A1 (enExample) |
| EA (1) | EA201391074A1 (enExample) |
| IL (1) | IL227643A0 (enExample) |
| MX (1) | MX2013008367A (enExample) |
| SG (1) | SG192108A1 (enExample) |
| WO (1) | WO2012103250A2 (enExample) |
| ZA (1) | ZA201305024B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| HRP20151294T1 (hr) | 2010-04-05 | 2016-03-11 | Prognosys Biosciences, Inc. | Biološka testiranja sa prostornim kodiranjem |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| US20130074201A1 (en) * | 2011-09-16 | 2013-03-21 | The Johns Hopkins University | Cancer-specific genetic rearrangements |
| EP3511423B2 (en) * | 2012-10-17 | 2024-05-29 | Spatial Transcriptomics AB | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| LT3013984T (lt) | 2013-06-25 | 2023-06-12 | Prognosys Biosciences, Inc. | Biologinių taikinių erdvinių modelių mėginyje nustatymo būdai |
| US9652722B1 (en) * | 2013-12-05 | 2017-05-16 | The Mathworks, Inc. | Methods and systems for robust supervised machine learning |
| ES2713240T3 (es) * | 2014-02-17 | 2019-05-20 | Ventana Med Syst Inc | Proteína asociada a vesícula que interacciona con G-alfa (GIV) como marcador predictivo en cáncer colorrectal de estadio II |
| US10407737B2 (en) | 2014-04-10 | 2019-09-10 | Bio-Marcare Technologies Ltd. | Methods and kits for identifying pre-cancerous colorectal polyps and colorectal cancer |
| CN120425026A (zh) | 2015-04-10 | 2025-08-05 | 十程基因技术瑞典公司 | 生物样本的空间区别、多重核酸分析 |
| CN108020672A (zh) * | 2016-11-03 | 2018-05-11 | 中国医学科学院基础医学研究所 | 检测rhbdd1蛋白的elisa方法及试剂盒 |
| US20200088748A1 (en) * | 2016-12-08 | 2020-03-19 | Dana-Farber Cancer Institute, Inc. | Metabolic profiling of fixed samples |
| CN107158388B (zh) * | 2017-07-11 | 2021-03-23 | 上海市第一人民医院 | MIIP pS303阻断剂在制备抗肿瘤药物中的应用 |
| US11414707B2 (en) * | 2018-01-22 | 2022-08-16 | Liquid Biopsy Research LLC | Methods for colon cancer detection and treatment |
| US12498372B2 (en) | 2018-04-12 | 2025-12-16 | Board Of Regents, The University Of Texas System | Biomarker for detecting cancer |
| JP2020028278A (ja) * | 2018-08-24 | 2020-02-27 | 国立大学法人九州大学 | 被検体に生じるイベントを予測するための判別器の生成方法、及び前記判別器を用いた被検体の層別化方法 |
| CN111321220A (zh) * | 2018-12-14 | 2020-06-23 | 中国医学科学院肿瘤医院 | 用于检测直肠癌放化疗敏感性的组合物、微阵列和计算机系统 |
| CN110079607B (zh) * | 2019-04-04 | 2022-08-02 | 陕西师范大学 | 一种引物组、检测血液样品种属的方法及应用 |
| WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| EP4025692A2 (en) | 2020-06-02 | 2022-07-13 | 10X Genomics, Inc. | Nucleic acid library methods |
| EP4600376A3 (en) | 2020-06-02 | 2025-10-22 | 10X Genomics, Inc. | Spatial transcriptomics for antigen-receptors |
| EP4421186B1 (en) | 2020-06-08 | 2025-08-13 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| EP4172621A1 (en) * | 2020-06-30 | 2023-05-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapies |
| CN111951883A (zh) * | 2020-08-04 | 2020-11-17 | 广东省第二人民医院(广东省卫生应急医院) | 一种特征mRNA表达谱组合及结肠癌早期预测方法 |
| CN115786518A (zh) * | 2022-11-29 | 2023-03-14 | 广东医科大学附属医院 | 嗅素结构域家族蛋白4(olfm4)在结肠癌检测产品中的应用 |
| US20240327927A1 (en) * | 2023-03-27 | 2024-10-03 | Immunis.Ai, Inc. | Active surveillance and risk stratification for prostate cancer |
| CN119372311A (zh) * | 2024-09-30 | 2025-01-28 | 东南大学 | 基于成纤维细胞相关基因的结肠癌预后和治疗抵抗预测模型的构建方法和应用 |
| CN120009551B (zh) * | 2025-02-27 | 2025-08-15 | 西南医科大学 | 剪接因子wbp11及其抑制剂的用途、预防或治疗结直肠癌的药物 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU575586B2 (en) | 1983-09-02 | 1988-08-04 | Syngene, Inc. | Oligonucleotide synthesis employing primer with oxidzable substituents in system |
| AU622426B2 (en) | 1987-12-11 | 1992-04-09 | Abbott Laboratories | Assay using template-dependent nucleic acid probe reorganization |
| GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
| DE68926504T2 (de) | 1988-07-20 | 1996-09-12 | David Segev | Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen |
| US5219727A (en) | 1989-08-21 | 1993-06-15 | Hoffmann-Laroche Inc. | Quantitation of nucleic acids using the polymerase chain reaction |
| US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
| US5554501A (en) | 1992-10-29 | 1996-09-10 | Beckman Instruments, Inc. | Biopolymer synthesis using surface activated biaxially oriented polypropylene |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| DE69503126T2 (de) | 1994-05-05 | 1998-11-12 | Beckman Instruments Inc | Repetitive oligonukleotide matrix |
| CA2195209C (en) | 1994-07-15 | 2008-09-23 | Roy R. Sooknanan | Use of rna polymerase to improve nucleic acid amplification process |
| AT402203B (de) | 1995-06-13 | 1997-03-25 | Himmler Gottfried Dipl Ing Dr | Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren |
| US5716784A (en) | 1996-02-05 | 1998-02-10 | The Perkin-Elmer Corporation | Fluorescence detection assay for homogeneous PCR hybridization systems |
| JP4468488B2 (ja) | 1996-05-29 | 2010-05-26 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 組み合せたリガーゼ検出およびポリメラーゼ連鎖反応を用いる核酸配列相違の検出 |
| US5985567A (en) | 1997-08-15 | 1999-11-16 | Beckman Coulter, Inc. | Hybridization detection by pretreating bound single-stranded probes |
| US6013789A (en) | 1998-02-20 | 2000-01-11 | Beckman Coulter, Inc. | Covalent attachment of biomolecules to derivatized polypropylene supports |
| US20010055596A1 (en) | 2000-03-24 | 2001-12-27 | Meagher Madeleine Joy | Compositions and methods for therapy and diagnosis of colon cancer |
| EP1534739A4 (en) * | 2002-01-18 | 2006-05-31 | Bristol Myers Squibb Co | IDENTIFICATION OF POLYNUCLEOTIDES AND POLYPEPTIDES FOR PREDICTING THE ACTIVITY OF COMPOUNDS THAT INTERACT WITH TYROSINE KINASE PROTEINS AND / OR TYROSINE KINASE PROTEIN PATHWAYS |
| JP2006507841A (ja) * | 2002-11-14 | 2006-03-09 | ダーマコン, インコーポレイテッド | 機能的siRNAおよび超機能的siRNA |
| US7250496B2 (en) * | 2002-11-14 | 2007-07-31 | Rosetta Genomics Ltd. | Bioinformatically detectable group of novel regulatory genes and uses thereof |
| US20040146921A1 (en) | 2003-01-24 | 2004-07-29 | Bayer Pharmaceuticals Corporation | Expression profiles for colon cancer and methods of use |
| US20050287544A1 (en) | 2003-12-01 | 2005-12-29 | Francois Bertucci | Gene expression profiling of colon cancer with DNA arrays |
| JP2008504803A (ja) * | 2004-01-09 | 2008-02-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 遺伝子発現の細胞型特異的パターン |
| WO2005083128A2 (en) | 2004-02-25 | 2005-09-09 | University Of South Florida | Methods for predicting cancer outcome and gene signatures for use therein |
| US20060195266A1 (en) | 2005-02-25 | 2006-08-31 | Yeatman Timothy J | Methods for predicting cancer outcome and gene signatures for use therein |
| AU2005250494B2 (en) | 2004-06-03 | 2010-12-23 | National Institute Of Health | Methods of screening for cell proliferation or neoplastic disorders |
| JP2008518610A (ja) | 2004-11-03 | 2008-06-05 | アルマック ダイアグノスティックス リミテッド | トランスクリプトームマイクロアレイ技法およびそれを使用する方法 |
| WO2007048074A1 (en) * | 2005-10-21 | 2007-04-26 | Genenews Inc. | Method and apparatus for correlating levels of biomarker products with disease |
| DK1974058T3 (da) * | 2006-01-11 | 2014-09-01 | Genomic Health Inc | Genekspressionsmarkører til prognosticering af kolorektal cancer |
| WO2007112330A2 (en) | 2006-03-24 | 2007-10-04 | Diadexus, Inc. | Compositions and methods for detection, prognosis and treatment of colon cancer |
| WO2008093323A2 (en) * | 2007-01-29 | 2008-08-07 | Compugen Ltd. | Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis |
| NZ562237A (en) | 2007-10-05 | 2011-02-25 | Pacific Edge Biotechnology Ltd | Proliferation signature and prognosis for gastrointestinal cancer |
| WO2009144581A1 (en) | 2008-05-27 | 2009-12-03 | Dako Denmark A/S | Hybridization compositions and methods |
| WO2010060055A1 (en) | 2008-11-21 | 2010-05-27 | Duke University | Predicting cancer risk and treatment success |
-
2012
- 2012-01-25 EA EA201391074A patent/EA201391074A1/ru unknown
- 2012-01-25 US US13/981,601 patent/US10196691B2/en not_active Expired - Fee Related
- 2012-01-25 CN CN201280010123.2A patent/CN103403543B9/zh not_active Expired - Fee Related
- 2012-01-25 WO PCT/US2012/022594 patent/WO2012103250A2/en not_active Ceased
- 2012-01-25 SG SG2013056254A patent/SG192108A1/en unknown
- 2012-01-25 MX MX2013008367A patent/MX2013008367A/es unknown
- 2012-01-25 AU AU2012209074A patent/AU2012209074A1/en not_active Abandoned
- 2012-01-25 JP JP2013551314A patent/JP2014509189A/ja active Pending
- 2012-01-25 EP EP12739742.0A patent/EP2668296B1/en not_active Not-in-force
- 2012-01-25 KR KR1020137021973A patent/KR20140006898A/ko not_active Withdrawn
- 2012-01-25 CA CA2825218A patent/CA2825218A1/en not_active Abandoned
- 2012-01-25 BR BR112013018924-0A patent/BR112013018924A2/en not_active IP Right Cessation
-
2013
- 2013-07-04 ZA ZA2013/05024A patent/ZA201305024B/en unknown
- 2013-07-24 IL IL227643A patent/IL227643A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014509189A (ja) | 2014-04-17 |
| WO2012103250A3 (en) | 2012-10-11 |
| SG192108A1 (en) | 2013-08-30 |
| US20140094379A1 (en) | 2014-04-03 |
| WO2012103250A2 (en) | 2012-08-02 |
| EP2668296A2 (en) | 2013-12-04 |
| EP2668296B1 (en) | 2018-08-15 |
| EA201391074A1 (ru) | 2013-12-30 |
| CN103403543B9 (zh) | 2017-05-17 |
| CA2825218A1 (en) | 2012-08-02 |
| KR20140006898A (ko) | 2014-01-16 |
| BR112013018924A2 (en) | 2018-05-08 |
| AU2012209074A1 (en) | 2013-07-11 |
| ZA201305024B (en) | 2014-03-26 |
| IL227643A0 (en) | 2013-09-30 |
| CN103403543B (zh) | 2016-11-09 |
| EP2668296A4 (en) | 2015-09-02 |
| CN103403543A (zh) | 2013-11-20 |
| NZ612471A (en) | 2015-11-27 |
| US10196691B2 (en) | 2019-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2013008367A (es) | Firmas de esxpresion genetica de cancer de colon y metodos de uso. | |
| IL268974B (en) | Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer | |
| EP2611941A4 (en) | GENESIS OF CANCER DIAGNOSIS AND PROGNOSIS | |
| MX346973B (es) | Anticuerpos especificos de tumores y usos para los mismos. | |
| MX2014000292A (es) | Usos de inhibidores etiquetados hsp90. | |
| CO7350624A2 (es) | Inhibidores de la tirosina-quinasa de bruton | |
| MX2013005762A (es) | Biomarcadores para la prediccion de la eficacia de una inmunoterapia contra el cancer. | |
| CY1118001T1 (el) | Νεες ctla4-ig προσκολλητινες | |
| CR20120406A (es) | Identificación de mutación lkb1 como un biomarcador predictivo para sensibilidad a inhibidores de tor cinasa | |
| CL2017001110A1 (es) | Métodos para seleccionar una línea de células t y donador de la misma para terapia celular adoptiva | |
| EA201171367A1 (ru) | Винилиндазолильные соединения | |
| BR112014011925A2 (pt) | mutações no receptor notch humano e seu uso | |
| CY1121185T1 (el) | Αδενοϊος που εκφραζει fas-χιμαιρα και χρηση αυτης σε μεθοδους θεραπειας καρκινου | |
| MX2015004610A (es) | Metodo para diagnostico, pronostico y tratamiento de metastasis de cancer de prostata usando c-maf. | |
| GT201500249A (es) | Terapia de combinación | |
| EA201590650A1 (ru) | Антиандрогены для лечения неметастатического кастрационно-резистентного рака простаты | |
| AR090129A1 (es) | Oligonucleotidos para la modulacion de la expresion genica y sus usos | |
| CL2013003324A1 (es) | Composicion que comprende quimioterapia con paclitaxel y carboplatino y un oligonucleotido anti-clusterina; uso de la composición para el tratamiento de un paciente humano que padece cancer de pulmón. | |
| WO2013028554A3 (en) | Gene signatures for lung cancer prognosis and therapy selection | |
| MX2015002749A (es) | Metodo diagnostico y terapeutico para el cancer dirigido a moleculas expresadas en celulas madre cancerosas. | |
| MX2015001788A (es) | Metabolitos de metionina predicen la evolución agresiva del cáncer. | |
| BR112012025196A2 (pt) | prognóstico com base genética da reincidência do antígeno prostático específico (psa) para pacientes com câncer de próstata clinicamente localizado | |
| AR083241A1 (es) | Metodos y kits para el diagnostico de cancer de prostata | |
| TR201111743A2 (tr) | Kanser tedavisinde kullanılmak üzere yağ bazlı nanotaşıyıcı sistemler. | |
| WO2011153485A3 (en) | Use of the sparc microenvironment signature in the treatment of cancer |