EA201391074A1 - Профили экспрессии генов рака толстой кишки и способы применения - Google Patents
Профили экспрессии генов рака толстой кишки и способы примененияInfo
- Publication number
- EA201391074A1 EA201391074A1 EA201391074A EA201391074A EA201391074A1 EA 201391074 A1 EA201391074 A1 EA 201391074A1 EA 201391074 A EA201391074 A EA 201391074A EA 201391074 A EA201391074 A EA 201391074A EA 201391074 A1 EA201391074 A1 EA 201391074A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- cancer
- colon cancer
- profiles
- methods
- expression profile
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 5
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title 1
- 206010009944 Colon cancer Diseases 0.000 abstract 5
- 208000029742 colonic neoplasm Diseases 0.000 abstract 5
- 238000011226 adjuvant chemotherapy Methods 0.000 abstract 2
- 238000002493 microarray Methods 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
- 238000002271 resection Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161435922P | 2011-01-25 | 2011-01-25 | |
| PCT/US2012/022594 WO2012103250A2 (en) | 2011-01-25 | 2012-01-25 | Colon cancer gene expression signatures and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201391074A1 true EA201391074A1 (ru) | 2013-12-30 |
Family
ID=46581385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201391074A EA201391074A1 (ru) | 2011-01-25 | 2012-01-25 | Профили экспрессии генов рака толстой кишки и способы применения |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10196691B2 (enExample) |
| EP (1) | EP2668296B1 (enExample) |
| JP (1) | JP2014509189A (enExample) |
| KR (1) | KR20140006898A (enExample) |
| CN (1) | CN103403543B9 (enExample) |
| AU (1) | AU2012209074A1 (enExample) |
| BR (1) | BR112013018924A2 (enExample) |
| CA (1) | CA2825218A1 (enExample) |
| EA (1) | EA201391074A1 (enExample) |
| IL (1) | IL227643A0 (enExample) |
| MX (1) | MX2013008367A (enExample) |
| SG (1) | SG192108A1 (enExample) |
| WO (1) | WO2012103250A2 (enExample) |
| ZA (1) | ZA201305024B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2556171E (pt) | 2010-04-05 | 2015-12-21 | Prognosys Biosciences Inc | Ensaios biológicos codificados espacialmente |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| US20130074201A1 (en) * | 2011-09-16 | 2013-03-21 | The Johns Hopkins University | Cancer-specific genetic rearrangements |
| DK3511423T4 (da) * | 2012-10-17 | 2024-07-29 | Spatial Transcriptomics Ab | Fremgangsmåder og produkt til optimering af lokaliseret eller rumlig detektion af genekspression i en vævsprøve |
| EP4234716A3 (en) | 2013-06-25 | 2023-12-06 | Prognosys Biosciences, Inc. | Methods for determining spatial patterns of biological targets in a sample |
| US9652722B1 (en) * | 2013-12-05 | 2017-05-16 | The Mathworks, Inc. | Methods and systems for robust supervised machine learning |
| WO2015121465A1 (en) * | 2014-02-17 | 2015-08-20 | Ventana Medical Systems, Inc. | G-alpha, interacting vesicle associated protein (giv) as a predictive marker in stage ii colorectal cancer |
| CN106460047B (zh) * | 2014-04-10 | 2019-11-26 | 比奥马卡尔技术有限公司 | 用于鉴定癌前结肠直肠息肉和结肠直肠癌的方法及试剂盒 |
| EP4119677B1 (en) | 2015-04-10 | 2023-06-28 | Spatial Transcriptomics AB | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| CN108020672A (zh) * | 2016-11-03 | 2018-05-11 | 中国医学科学院基础医学研究所 | 检测rhbdd1蛋白的elisa方法及试剂盒 |
| WO2018107023A1 (en) * | 2016-12-08 | 2018-06-14 | Dana-Farber Cancer Institute, Inc. | Metabolic profiling of fixed samples |
| CN107158388B (zh) * | 2017-07-11 | 2021-03-23 | 上海市第一人民医院 | MIIP pS303阻断剂在制备抗肿瘤药物中的应用 |
| EP3743534B1 (en) * | 2018-01-22 | 2022-03-23 | Liquid Biopsy Research LLC | Methods for colon cancer detection and treatment monitoring |
| AU2019252672B2 (en) * | 2018-04-12 | 2025-08-14 | Board Of Regents, The University Of Texas System | Biomarker for detecting cancer |
| JP2020028278A (ja) * | 2018-08-24 | 2020-02-27 | 国立大学法人九州大学 | 被検体に生じるイベントを予測するための判別器の生成方法、及び前記判別器を用いた被検体の層別化方法 |
| CN111321220A (zh) * | 2018-12-14 | 2020-06-23 | 中国医学科学院肿瘤医院 | 用于检测直肠癌放化疗敏感性的组合物、微阵列和计算机系统 |
| CN110079607B (zh) * | 2019-04-04 | 2022-08-02 | 陕西师范大学 | 一种引物组、检测血液样品种属的方法及应用 |
| EP3976820A1 (en) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| WO2021247568A1 (en) | 2020-06-02 | 2021-12-09 | 10X Genomics, Inc. | Spatial trancriptomics for antigen-receptors |
| EP4025692A2 (en) | 2020-06-02 | 2022-07-13 | 10X Genomics, Inc. | Nucleic acid library methods |
| ES2981265T3 (es) | 2020-06-08 | 2024-10-08 | 10X Genomics Inc | Métodos para determinar un margen quirúrgico y métodos de uso del mismo |
| WO2022002873A1 (en) * | 2020-06-30 | 2022-01-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapies |
| CN111951883A (zh) * | 2020-08-04 | 2020-11-17 | 广东省第二人民医院（广东省卫生应急医院） | 一种特征mRNA表达谱组合及结肠癌早期预测方法 |
| CN115786518A (zh) * | 2022-11-29 | 2023-03-14 | 广东医科大学附属医院 | 嗅素结构域家族蛋白4（olfm4）在结肠癌检测产品中的应用 |
| WO2024206495A2 (en) * | 2023-03-27 | 2024-10-03 | Immunis.Ai, Inc. | Active surveillance and risk stratification for prostate cancer |
| CN119372311A (zh) * | 2024-09-30 | 2025-01-28 | 东南大学 | 基于成纤维细胞相关基因的结肠癌预后和治疗抵抗预测模型的构建方法和应用 |
| CN120009551B (zh) * | 2025-02-27 | 2025-08-15 | 西南医科大学 | 剪接因子wbp11及其抑制剂的用途、预防或治疗结直肠癌的药物 |
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| AU575586B2 (en) | 1983-09-02 | 1988-08-04 | Syngene, Inc. | Oligonucleotide synthesis employing primer with oxidzable substituents in system |
| CA1323293C (en) | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
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| JP2955759B2 (ja) | 1988-07-20 | 1999-10-04 | セゲブ・ダイアグノスティックス・インコーポレイテッド | 核酸配列を増幅及び検出する方法 |
| US5219727A (en) | 1989-08-21 | 1993-06-15 | Hoffmann-Laroche Inc. | Quantitation of nucleic acids using the polymerase chain reaction |
| US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
| US5554501A (en) | 1992-10-29 | 1996-09-10 | Beckman Instruments, Inc. | Biopolymer synthesis using surface activated biaxially oriented polypropylene |
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| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
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| WO1996002668A1 (en) | 1994-07-15 | 1996-02-01 | Azco Nobel N.V. | Use of rna polymerase to improve nucleic acid amplification process |
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| US5716784A (en) | 1996-02-05 | 1998-02-10 | The Perkin-Elmer Corporation | Fluorescence detection assay for homogeneous PCR hybridization systems |
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| TW200730825A (en) * | 2005-10-21 | 2007-08-16 | Genenews Inc | Method and apparatus for correlating levels of biomarker products with disease |
| KR20090003178A (ko) * | 2006-01-11 | 2009-01-09 | 게노믹 헬쓰, 인코포레이티드 | 직장결장암 예후에 대한 유전자 발현 마커 |
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| US20100261169A1 (en) * | 2007-01-29 | 2010-10-14 | Shira Wallach | Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis |
| NZ562237A (en) * | 2007-10-05 | 2011-02-25 | Pacific Edge Biotechnology Ltd | Proliferation signature and prognosis for gastrointestinal cancer |
| WO2009147537A2 (en) | 2008-05-27 | 2009-12-10 | Dako Denmark A/S | Compositions and methods for detection of chromosomal aberrations with novel hybridization buffers |
| WO2010060055A1 (en) | 2008-11-21 | 2010-05-27 | Duke University | Predicting cancer risk and treatment success |
-
2012
- 2012-01-25 AU AU2012209074A patent/AU2012209074A1/en not_active Abandoned
- 2012-01-25 JP JP2013551314A patent/JP2014509189A/ja active Pending
- 2012-01-25 MX MX2013008367A patent/MX2013008367A/es unknown
- 2012-01-25 EA EA201391074A patent/EA201391074A1/ru unknown
- 2012-01-25 CN CN201280010123.2A patent/CN103403543B9/zh not_active Expired - Fee Related
- 2012-01-25 SG SG2013056254A patent/SG192108A1/en unknown
- 2012-01-25 US US13/981,601 patent/US10196691B2/en not_active Expired - Fee Related
- 2012-01-25 CA CA2825218A patent/CA2825218A1/en not_active Abandoned
- 2012-01-25 WO PCT/US2012/022594 patent/WO2012103250A2/en not_active Ceased
- 2012-01-25 EP EP12739742.0A patent/EP2668296B1/en not_active Not-in-force
- 2012-01-25 BR BR112013018924A patent/BR112013018924A2/pt not_active IP Right Cessation
- 2012-01-25 KR KR1020137021973A patent/KR20140006898A/ko not_active Withdrawn
-
2013
- 2013-07-04 ZA ZA2013/05024A patent/ZA201305024B/en unknown
- 2013-07-24 IL IL227643A patent/IL227643A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2668296A4 (en) | 2015-09-02 |
| CN103403543B (zh) | 2016-11-09 |
| AU2012209074A1 (en) | 2013-07-11 |
| IL227643A0 (en) | 2013-09-30 |
| US10196691B2 (en) | 2019-02-05 |
| BR112013018924A2 (pt) | 2018-05-08 |
| SG192108A1 (en) | 2013-08-30 |
| ZA201305024B (en) | 2014-03-26 |
| CN103403543B9 (zh) | 2017-05-17 |
| WO2012103250A3 (en) | 2012-10-11 |
| EP2668296B1 (en) | 2018-08-15 |
| EP2668296A2 (en) | 2013-12-04 |
| US20140094379A1 (en) | 2014-04-03 |
| JP2014509189A (ja) | 2014-04-17 |
| CA2825218A1 (en) | 2012-08-02 |
| CN103403543A (zh) | 2013-11-20 |
| MX2013008367A (es) | 2013-08-12 |
| KR20140006898A (ko) | 2014-01-16 |
| NZ612471A (en) | 2015-11-27 |
| WO2012103250A2 (en) | 2012-08-02 |
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