JP2014221816A5 - - Google Patents
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- Publication number
- JP2014221816A5 JP2014221816A5 JP2014148568A JP2014148568A JP2014221816A5 JP 2014221816 A5 JP2014221816 A5 JP 2014221816A5 JP 2014148568 A JP2014148568 A JP 2014148568A JP 2014148568 A JP2014148568 A JP 2014148568A JP 2014221816 A5 JP2014221816 A5 JP 2014221816A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polymer
- poly
- cellulose
- excipients
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95704407P | 2007-08-21 | 2007-08-21 | |
| US60/957,044 | 2007-08-21 | ||
| US5092208P | 2008-05-06 | 2008-05-06 | |
| US61/050,922 | 2008-05-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Division JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014221816A JP2014221816A (ja) | 2014-11-27 |
| JP2014221816A5 true JP2014221816A5 (enExample) | 2015-01-15 |
Family
ID=40378995
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Active JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
| JP2014148568A Withdrawn JP2014221816A (ja) | 2007-08-21 | 2014-07-22 | 医薬品適用のための熱−動力学的混合 |
| JP2016076558A Withdrawn JP2016121195A (ja) | 2007-08-21 | 2016-04-06 | 医薬品適用のための熱−動力学的混合 |
| JP2018226362A Withdrawn JP2019052173A (ja) | 2007-08-21 | 2018-12-03 | 医薬品適用のための熱−動力学的混合 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Active JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016076558A Withdrawn JP2016121195A (ja) | 2007-08-21 | 2016-04-06 | 医薬品適用のための熱−動力学的混合 |
| JP2018226362A Withdrawn JP2019052173A (ja) | 2007-08-21 | 2018-12-03 | 医薬品適用のための熱−動力学的混合 |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US8486423B2 (enExample) |
| EP (1) | EP2187968A4 (enExample) |
| JP (4) | JP6073043B2 (enExample) |
| CN (1) | CN101835492B (enExample) |
| CA (3) | CA3076115C (enExample) |
| WO (1) | WO2009026461A2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8821928B2 (en) | 2007-06-04 | 2014-09-02 | Egalet Ltd. | Controlled release pharmaceutical compositions for prolonged effect |
| WO2009026461A2 (en) | 2007-08-21 | 2009-02-26 | Board Of Regents, The University Of Texas System | Thermo-kinetic mixing for pharmaceutical applications |
| US9545361B1 (en) * | 2011-07-25 | 2017-01-17 | Dispersol Technologies, Llc | Multiple speed process for preserving heat sensitive portions of a thermokinetically melt blended batch |
| AU2009268923B2 (en) | 2008-06-16 | 2015-09-17 | Pfizer Inc. | Drug loaded polymeric nanoparticles and methods of making and using same |
| WO2010005726A2 (en) | 2008-06-16 | 2010-01-14 | Bind Biosciences Inc. | Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same |
| EA020753B1 (ru) | 2008-06-16 | 2015-01-30 | Бинд Терапьютикс, Инк. | Терапевтические полимерные наночастицы, содержащие алкалоиды vinca, и их применение |
| US8809261B2 (en) * | 2008-10-31 | 2014-08-19 | Elsohly Laboratories, Incorporated | Compositions containing delta-9-THC-amino acid esters and process of preparation |
| WO2010068866A2 (en) | 2008-12-12 | 2010-06-17 | Bind Biosciences | Therapeutic particles suitable for parenteral administration and methods of making and using same |
| EA201100765A1 (ru) * | 2008-12-15 | 2012-04-30 | Бинд Биосаиэнсис | Наночастицы длительной циркуляции для замедленного высвобождения терапевтических средств |
| NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
| AU2010265213B2 (en) | 2009-06-24 | 2012-08-23 | Egalet Ltd. | Controlled release formulations |
| CN102811743B (zh) | 2009-12-11 | 2015-11-25 | 佰恩德治疗股份有限公司 | 冻干治疗颗粒的稳定制剂 |
| JP5965844B2 (ja) | 2009-12-15 | 2016-08-10 | バインド セラピューティックス インコーポレイテッド | 高いガラス転移温度または高分子量のコポリマーを有する治療用ポリマーナノ粒子組成物 |
| US20140039031A1 (en) * | 2011-02-23 | 2014-02-06 | Dispersol Technologies. LLC | Pharmaceutical formulations of acetyl-11-keto-b-boswellic acid, diindolylmethane, and curcumin for pharmaceutical applications |
| CN102204868B (zh) * | 2011-05-18 | 2014-01-22 | 北京化工大学 | 采用多元辅料制备吲哚美辛速释制剂的热熔挤出工艺 |
| US9821283B1 (en) * | 2011-07-25 | 2017-11-21 | Dispersol Technologies, Llc | Direct probe sensed temperature method for speed change for heat sensitive portions of a thermokinetically melt blended batch |
| HUE043998T2 (hu) | 2012-09-17 | 2019-09-30 | Pfizer | Eljárás terápiás nanorészecskék elõállítására |
| CN113209024A (zh) | 2013-12-31 | 2021-08-06 | 阿森迪亚制药有限责任公司 | 疏水性化合物的药物组合物 |
| EP3116547B1 (en) | 2014-03-14 | 2019-06-05 | Pfizer Inc | Therapeutic nanoparticles comprising a therapeutic agent and methods of making and using same |
| WO2015141662A1 (ja) * | 2014-03-18 | 2015-09-24 | 武田薬品工業株式会社 | 固体分散体 |
| AU2014391109B2 (en) * | 2014-04-18 | 2019-01-17 | AustinPx, LLC | Multiple speed process for preserving heat sensitive portions of a thermokinetically melt blended batch |
| US20170333404A1 (en) * | 2014-11-03 | 2017-11-23 | Dispersol Technologies, Llc | Improved formulations of vemurafenib and methods of making the same |
| CN107205935A (zh) * | 2015-01-20 | 2017-09-26 | 默克专利股份有限公司 | 用聚乙烯醇作载体聚合物的化合物固体分散体 |
| JP2018517734A (ja) | 2015-06-17 | 2018-07-05 | ディスパーソル テクノロジーズ リミテッド ライアビリティ カンパニー | デフェラシロクスの改善された製剤およびその作製方法 |
| TWI799366B (zh) | 2015-09-15 | 2023-04-21 | 美商建南德克公司 | 胱胺酸結骨架平臺 |
| CN109069460A (zh) * | 2016-05-09 | 2018-12-21 | 分散技术有限责任公司 | 改进的药物制剂 |
| DK3454906T3 (da) | 2016-05-13 | 2025-10-20 | Merck Patent Gmbh | Partikelstørrelse og fordeling af polymer til smelteekstruderingsanvendelse |
| JP7376220B2 (ja) * | 2017-09-11 | 2023-11-08 | オースティンピーエックス リミテッド ライアビリティ カンパニー | 熱動力学的に溶融ブレンドされるバッチの熱感受性部分用の、直接プローブにより感知した温度による、速度変更のための方法 |
| MA50189A (fr) * | 2017-09-22 | 2021-05-19 | Dispersol Technologies Llc | Formulations pharmaceutiques d'oligomère cyclique et d'abiratérone et procédés de formation et d'administration de celles-ci |
| CN109663524B (zh) * | 2017-10-13 | 2022-07-15 | 分散技术有限责任公司 | 用于热动力学熔体共混批次的热敏部分的速度改变的直接进样探头感测温度方法 |
| HUE052986T2 (hu) | 2017-10-13 | 2021-05-28 | Dispersol Technologies Llc | Sebességváltoztatási eljárás közvetlen szonda általi hõmérséklet-érzékeléssel egy termokinetikusan ömlesztve kevert töltet hõérzékeny részei számára |
| WO2019094688A1 (en) * | 2017-11-10 | 2019-05-16 | Dispersol Technologies, Llc | Improved drug formulations |
| EP3492070A1 (en) * | 2017-11-30 | 2019-06-05 | BIT Pharma GmbH | Process and device for preparing a solid dispersion |
| CN111742041B (zh) * | 2017-12-21 | 2023-06-06 | 丹尼斯科美国公司 | 包含耐热干燥剂的含酶的热熔细粒 |
| US20200147032A1 (en) | 2018-11-14 | 2020-05-14 | Robert K. Prud'homme | Dihydromyricetin hot melt extrusion formulations and methods for forming them |
| MX2021015457A (es) | 2019-06-14 | 2022-04-06 | Univ Princeton | Formulaciones de dihidromiricetina y un permeabilizante. |
| WO2021108022A1 (en) * | 2019-11-30 | 2021-06-03 | Dispersol Technologies, Llc | Inclusion complexes of pharmaceuticals and cyclic oligomers |
| KR20220130698A (ko) * | 2019-12-20 | 2022-09-27 | 에피자임, 인코포레이티드 | Ezh2 억제제의 결정질 하이드로브로마이드 염, 이의 제조 및 암의 치료에 유용한 약학적 조성물 |
| JP2023520018A (ja) | 2020-04-01 | 2023-05-15 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | ニクロサミドの薬学的組成物 |
| IL303390A (en) | 2020-12-03 | 2023-08-01 | Battelle Memorial Institute | Compositions of polymer nanoparticles and DNA nanostructures and methods for non-viral transport |
| US20240108639A1 (en) * | 2020-12-11 | 2024-04-04 | Board Of Regents, The University Of Texas System | Compositions and methods of making cocrystals using dielectric heating with dispersive and distributive mixing |
| AU2022250858A1 (en) * | 2021-04-01 | 2023-11-16 | Merck Patent Gmbh | Process for continuous hot melt granulation of low soluble pharmaceuticals |
| WO2022216977A1 (en) | 2021-04-07 | 2022-10-13 | Batelle Memorial Institute | Rapid design, build, test, and learn technologies for identifying and using non-viral carriers |
| US20250000794A1 (en) * | 2021-07-27 | 2025-01-02 | Board Of Regents, The University Of Texas System | Improved drug processing methods to increase drug loading |
| WO2023034844A1 (en) | 2021-08-31 | 2023-03-09 | Board Of Regents, The University Of Texas System | Delayed release niclosamide formulation |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| AU2024393766A1 (en) | 2023-12-08 | 2026-06-18 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
| AU2025207356A1 (en) | 2024-01-11 | 2026-08-06 | Minneamrita Therapeutics Llc | Triptolide formulations |
| CN119453203A (zh) * | 2025-01-09 | 2025-02-18 | 山东百农思达生物科技有限公司 | 一种含杀虫单和阿维菌素的复合微乳制剂及其制备工艺 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2319478A1 (fr) | 1975-07-30 | 1977-02-25 | Gen Electric | Extrudeuse et procede d'extrusion de materiaux thermoplastiques |
| US4230615A (en) * | 1978-11-21 | 1980-10-28 | Carlew Chemicals Limited | Process for controlled mixing in a high intensity mixer |
| US4628073A (en) | 1984-10-03 | 1986-12-09 | Monsanto Company | Soft, rubbery, multiphase matrix material and methods for its production |
| US4789597A (en) | 1987-01-12 | 1988-12-06 | Fetherstonhaugh & Co. | Incorporation of chemically reactive agents on resin particles |
| ES2111065T5 (es) * | 1991-04-16 | 2005-06-16 | Nippon Shinyaku Company, Limited | Procedimiento para producir una dispersion solida. |
| JP2516524B2 (ja) * | 1992-04-27 | 1996-07-24 | 大洋薬品工業株式会社 | 持続性製剤 |
| JPH07159587A (ja) | 1993-12-07 | 1995-06-23 | Hitachi Ltd | 樹脂性能モニタ |
| JPH07187998A (ja) * | 1993-12-27 | 1995-07-25 | Kao Corp | 錠剤の製造方法 |
| GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
| US5895790A (en) | 1995-03-14 | 1999-04-20 | Good; Elmer | Thermosetting wide range polymer blends |
| DE19531067A1 (de) | 1995-08-23 | 1997-02-27 | Hermann P T Prof Dr Med Ammon | Verwendung von Boswelliasäure und ihren Derivaten zur Hemmung der normalen und gesteigerten Leukozytenelastase- oder Plasminaktivität |
| US6509038B2 (en) * | 1996-05-20 | 2003-01-21 | Janssen Pharmaceutica N.V. | Antifungal compositions with improved bioavailability |
| AR028253A1 (es) | 2000-03-16 | 2003-04-30 | Pfizer Prod Inc | Inhibidores de la glucogeno fosforilasa |
| US6709146B1 (en) | 2000-07-28 | 2004-03-23 | David Little | Thermokinetic mixer and method of using |
| KR100759635B1 (ko) | 2001-06-22 | 2007-09-17 | 화이자 프로덕츠 인코포레이티드 | 비정질 약물의 흡착체의 약학 조성물 |
| KR20040011248A (ko) | 2002-07-30 | 2004-02-05 | 환인제약 주식회사 | 암로디핀의 고체분산체와 그 제조방법 및 그를 포함하는약학적 조성물 |
| CA2509958A1 (en) | 2003-02-03 | 2004-08-19 | Novartis Ag | Pharmaceutical formulation |
| GB0319797D0 (en) * | 2003-08-26 | 2003-09-24 | Leuven K U Res & Dev | Particle size reduction of poorly soluble drugs |
| US20050158376A1 (en) * | 2003-10-23 | 2005-07-21 | Sardi William F. | Dietary supplement and method of processing same |
| CN100563658C (zh) * | 2003-11-14 | 2009-12-02 | 味之素株式会社 | 苯丙氨酸衍生物的固体分散体或固体分散体医药制剂 |
| WO2005053851A1 (en) | 2003-11-26 | 2005-06-16 | E.I. Dupont De Nemours And Company | High pressure media milling system and process of milling particles |
| JP2005263758A (ja) * | 2004-03-22 | 2005-09-29 | Kirin Brewery Co Ltd | 非晶質のn−{2−クロロ−4−[(6,7−ジメトキシ−4−キナゾリニル)オキシ]フェニル}−n’−プロピルウレア |
| KR101086254B1 (ko) * | 2004-11-04 | 2011-11-24 | 에스케이케미칼주식회사 | 생체이용률이 개선된 프란루카스트 고체분산체 조성물 및그 고체분산체의 제조방법 |
| US20060264497A1 (en) | 2005-03-28 | 2006-11-23 | Zeligs Michael A | Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health |
| JP2006347939A (ja) * | 2005-06-15 | 2006-12-28 | Tokyo Printing Ink Mfg Co Ltd | 薬物高分子複合体の製造方法及び薬物高分子複合体 |
| JP4429262B2 (ja) * | 2005-12-09 | 2010-03-10 | 壽製薬株式会社 | フェノフィブラートの固体分散体 |
| US9545361B1 (en) * | 2011-07-25 | 2017-01-17 | Dispersol Technologies, Llc | Multiple speed process for preserving heat sensitive portions of a thermokinetically melt blended batch |
| WO2009026461A2 (en) * | 2007-08-21 | 2009-02-26 | Board Of Regents, The University Of Texas System | Thermo-kinetic mixing for pharmaceutical applications |
| JP2012047227A (ja) | 2010-08-25 | 2012-03-08 | Nippon Steel & Sumikin Metal Products Co Ltd | ナット保持部材 |
| US20140039031A1 (en) | 2011-02-23 | 2014-02-06 | Dispersol Technologies. LLC | Pharmaceutical formulations of acetyl-11-keto-b-boswellic acid, diindolylmethane, and curcumin for pharmaceutical applications |
| US20170333404A1 (en) | 2014-11-03 | 2017-11-23 | Dispersol Technologies, Llc | Improved formulations of vemurafenib and methods of making the same |
-
2008
- 2008-08-21 WO PCT/US2008/073913 patent/WO2009026461A2/en not_active Ceased
- 2008-08-21 CN CN2008801123533A patent/CN101835492B/zh active Active
- 2008-08-21 CA CA3076115A patent/CA3076115C/en active Active
- 2008-08-21 JP JP2010522038A patent/JP6073043B2/ja active Active
- 2008-08-21 EP EP08798412A patent/EP2187968A4/en not_active Ceased
- 2008-08-21 CA CA2990445A patent/CA2990445C/en active Active
- 2008-08-21 US US12/196,154 patent/US8486423B2/en active Active
- 2008-08-21 CA CA2697099A patent/CA2697099C/en active Active
-
2013
- 2013-07-15 US US13/942,199 patent/US9339440B2/en active Active
-
2014
- 2014-07-22 JP JP2014148568A patent/JP2014221816A/ja not_active Withdrawn
-
2016
- 2016-04-06 JP JP2016076558A patent/JP2016121195A/ja not_active Withdrawn
- 2016-05-13 US US15/154,083 patent/US10022385B2/en active Active
-
2018
- 2018-06-19 US US16/012,025 patent/US10668085B2/en active Active
- 2018-12-03 JP JP2018226362A patent/JP2019052173A/ja not_active Withdrawn
-
2020
- 2020-05-05 US US16/866,676 patent/US11439650B2/en active Active
-
2022
- 2022-07-25 US US17/814,567 patent/US12023343B2/en active Active
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