JP2014221816A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014221816A5 JP2014221816A5 JP2014148568A JP2014148568A JP2014221816A5 JP 2014221816 A5 JP2014221816 A5 JP 2014221816A5 JP 2014148568 A JP2014148568 A JP 2014148568A JP 2014148568 A JP2014148568 A JP 2014148568A JP 2014221816 A5 JP2014221816 A5 JP 2014221816A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polymer
- poly
- cellulose
- excipients
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95704407P | 2007-08-21 | 2007-08-21 | |
| US60/957,044 | 2007-08-21 | ||
| US5092208P | 2008-05-06 | 2008-05-06 | |
| US61/050,922 | 2008-05-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Division JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014221816A JP2014221816A (ja) | 2014-11-27 |
| JP2014221816A5 true JP2014221816A5 (enExample) | 2015-01-15 |
Family
ID=40378995
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Active JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
| JP2014148568A Withdrawn JP2014221816A (ja) | 2007-08-21 | 2014-07-22 | 医薬品適用のための熱−動力学的混合 |
| JP2016076558A Withdrawn JP2016121195A (ja) | 2007-08-21 | 2016-04-06 | 医薬品適用のための熱−動力学的混合 |
| JP2018226362A Withdrawn JP2019052173A (ja) | 2007-08-21 | 2018-12-03 | 医薬品適用のための熱−動力学的混合 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522038A Active JP6073043B2 (ja) | 2007-08-21 | 2008-08-21 | 医薬品適用のための熱−動力学的混合 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016076558A Withdrawn JP2016121195A (ja) | 2007-08-21 | 2016-04-06 | 医薬品適用のための熱−動力学的混合 |
| JP2018226362A Withdrawn JP2019052173A (ja) | 2007-08-21 | 2018-12-03 | 医薬品適用のための熱−動力学的混合 |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US8486423B2 (enExample) |
| EP (1) | EP2187968A4 (enExample) |
| JP (4) | JP6073043B2 (enExample) |
| CN (1) | CN101835492B (enExample) |
| CA (3) | CA3076115C (enExample) |
| WO (1) | WO2009026461A2 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008258596B2 (en) | 2007-06-04 | 2013-02-14 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
| US9545361B1 (en) * | 2011-07-25 | 2017-01-17 | Dispersol Technologies, Llc | Multiple speed process for preserving heat sensitive portions of a thermokinetically melt blended batch |
| WO2009026461A2 (en) | 2007-08-21 | 2009-02-26 | Board Of Regents, The University Of Texas System | Thermo-kinetic mixing for pharmaceutical applications |
| EP2309991B1 (en) | 2008-06-16 | 2019-03-06 | Pfizer Inc | Therapeutic polymeric nanoparticles comprising vinca alkaloids and methods of making and using same |
| WO2010005726A2 (en) | 2008-06-16 | 2010-01-14 | Bind Biosciences Inc. | Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same |
| EA020954B1 (ru) | 2008-06-16 | 2015-03-31 | Бинд Терапьютикс, Инк. | Загруженные лекарственным средством полимерные наночастицы, фармацевтическая композиция и способ лечения рака |
| PL2352497T3 (pl) * | 2008-10-31 | 2017-08-31 | University Of Mississippi | Proces przygotowania estrów aminokwasowych delta-9-thc |
| WO2010068866A2 (en) * | 2008-12-12 | 2010-06-17 | Bind Biosciences | Therapeutic particles suitable for parenteral administration and methods of making and using same |
| EP2379064B1 (en) | 2008-12-15 | 2020-02-26 | Pfizer Inc. | Long circulating nanoparticles for sustained release of therapeutic agents |
| NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
| WO2010149169A2 (en) | 2009-06-24 | 2010-12-29 | Egalet A/S | Controlled release formulations |
| TR201906255T4 (tr) | 2009-12-11 | 2019-05-21 | Pfizer | Terapötik partiküllerin liyofilize edilmesine yönelik stabil formülasyonlar. |
| ES2780156T3 (es) | 2009-12-15 | 2020-08-24 | Pfizer | Composiciones terapéuticas de nanopartículas poliméricas con alta temperatura de transición vítrea o copolímeros de alto peso molecular |
| US20140039031A1 (en) * | 2011-02-23 | 2014-02-06 | Dispersol Technologies. LLC | Pharmaceutical formulations of acetyl-11-keto-b-boswellic acid, diindolylmethane, and curcumin for pharmaceutical applications |
| CN102204868B (zh) * | 2011-05-18 | 2014-01-22 | 北京化工大学 | 采用多元辅料制备吲哚美辛速释制剂的热熔挤出工艺 |
| US9821283B1 (en) * | 2011-07-25 | 2017-11-21 | Dispersol Technologies, Llc | Direct probe sensed temperature method for speed change for heat sensitive portions of a thermokinetically melt blended batch |
| EP2895156B1 (en) | 2012-09-17 | 2019-05-08 | Pfizer Inc. | Process for preparing therapeutic nanoparticles |
| EP3089736B1 (en) * | 2013-12-31 | 2025-07-23 | Ascendia Pharmaceuticals, LLC | Pharmaceutical compositions for poorly water-soluble compounds |
| ES2834927T3 (es) | 2014-03-14 | 2021-06-21 | Pfizer | Nanopartículas terapéuticas que comprenden un agente terapéutico y procedimientos de fabricación y uso de las mismas |
| CA2943024A1 (en) * | 2014-03-18 | 2015-09-24 | Takeda Pharmaceutical Company Limited | Solid dispersion |
| LT3131667T (lt) * | 2014-04-18 | 2021-12-10 | Dispersol Technologies, Llc | Kelių sukimosi greičių būdas ir maišytuvas termokinetiškai išlydytos mišriosios partijos šilumai jautrioms dalims išlaikyti |
| US20170333404A1 (en) * | 2014-11-03 | 2017-11-23 | Dispersol Technologies, Llc | Improved formulations of vemurafenib and methods of making the same |
| EP3247334A1 (en) * | 2015-01-20 | 2017-11-29 | Merck Patent GmbH | Solid dispersions of compounds using polyvinyl alcohol as a carrier polymer |
| US10265301B2 (en) | 2015-06-17 | 2019-04-23 | Dispersol Technologies, Llc | Formulations of deferasirox and methods of making the same |
| TWI799366B (zh) | 2015-09-15 | 2023-04-21 | 美商建南德克公司 | 胱胺酸結骨架平臺 |
| CN109069460A (zh) * | 2016-05-09 | 2018-12-21 | 分散技术有限责任公司 | 改进的药物制剂 |
| KR20190008334A (ko) | 2016-05-13 | 2019-01-23 | 메르크 파텐트 게엠베하 | 용융 압출 적용을 위한 중합체의 입자 크기 및 분포 |
| JP7376220B2 (ja) * | 2017-09-11 | 2023-11-08 | オースティンピーエックス リミテッド ライアビリティ カンパニー | 熱動力学的に溶融ブレンドされるバッチの熱感受性部分用の、直接プローブにより感知した温度による、速度変更のための方法 |
| JP2020534320A (ja) * | 2017-09-22 | 2020-11-26 | ディスパーソル テクノロジーズ リミテッド ライアビリティ カンパニー | アビラテロン環状オリゴマー薬学的製剤ならびにその形成法および投与法 |
| ES2836192T3 (es) | 2017-10-13 | 2021-06-24 | Dispersol Technologies Llc | Método de detección de la temperatura por sonda directa para determinar el cambio de velocidad para porciones sensibles al calor de un lote combinado fundido termocinéticamente |
| CN109663524B (zh) * | 2017-10-13 | 2022-07-15 | 分散技术有限责任公司 | 用于热动力学熔体共混批次的热敏部分的速度改变的直接进样探头感测温度方法 |
| CN111511365A (zh) * | 2017-11-10 | 2020-08-07 | 分散技术有限责任公司 | 改进的药物制剂 |
| EP3492070A1 (en) * | 2017-11-30 | 2019-06-05 | BIT Pharma GmbH | Process and device for preparing a solid dispersion |
| ES3058679T3 (en) * | 2017-12-21 | 2026-03-12 | Danisco Us Inc | Enzyme-containing, hot-melt granules comprising a thermotolerant desiccant |
| US20200147032A1 (en) | 2018-11-14 | 2020-05-14 | Robert K. Prud'homme | Dihydromyricetin hot melt extrusion formulations and methods for forming them |
| WO2021108022A1 (en) * | 2019-11-30 | 2021-06-03 | Dispersol Technologies, Llc | Inclusion complexes of pharmaceuticals and cyclic oligomers |
| CA3162315A1 (en) * | 2019-12-20 | 2021-06-24 | Marinus Jacobus Verwijs | Crystalline hydrobromide salt of a ezh2 inhibitor, its preparation and pharmaceutical composition useful for the treatment of cancer |
| EP4125923A1 (en) | 2020-04-01 | 2023-02-08 | Board of Regents, The University of Texas System | Pharmaceutical compositions of niclosamide |
| CN116887866A (zh) | 2020-12-03 | 2023-10-13 | 巴特尔纪念研究院 | 聚合物纳米颗粒和dna纳米结构组合物及用于非病毒递送的方法 |
| WO2022125869A1 (en) * | 2020-12-11 | 2022-06-16 | Board Of Regents, The University Of Texas System | Compositions and methods of making cocrystals using dielectric heating with dispersive and distributive mixing |
| EP4312990A1 (en) * | 2021-04-01 | 2024-02-07 | Merck Patent GmbH | Process for continuous hot melt granulation of low soluble pharmaceuticals |
| JP2024516108A (ja) | 2021-04-07 | 2024-04-12 | バテル・メモリアル・インスティテュート | 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術 |
| US20250000794A1 (en) * | 2021-07-27 | 2025-01-02 | Board Of Regents, The University Of Texas System | Improved drug processing methods to increase drug loading |
| US20230112800A1 (en) | 2021-08-31 | 2023-04-13 | Board Of Regents, The University Of Texas System | Delayed release niclosamide formulation |
| WO2025072751A1 (en) | 2023-09-29 | 2025-04-03 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| US12441996B2 (en) | 2023-12-08 | 2025-10-14 | Battelle Memorial Institute | Use of DNA origami nanostructures for molecular information based data storage systems |
| CN119453203A (zh) * | 2025-01-09 | 2025-02-18 | 山东百农思达生物科技有限公司 | 一种含杀虫单和阿维菌素的复合微乳制剂及其制备工艺 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2319478A1 (fr) | 1975-07-30 | 1977-02-25 | Gen Electric | Extrudeuse et procede d'extrusion de materiaux thermoplastiques |
| US4230615A (en) * | 1978-11-21 | 1980-10-28 | Carlew Chemicals Limited | Process for controlled mixing in a high intensity mixer |
| US4628073A (en) | 1984-10-03 | 1986-12-09 | Monsanto Company | Soft, rubbery, multiphase matrix material and methods for its production |
| US4789597A (en) | 1987-01-12 | 1988-12-06 | Fetherstonhaugh & Co. | Incorporation of chemically reactive agents on resin particles |
| AU1537292A (en) * | 1991-04-16 | 1992-11-17 | Nippon Shinyaku Co. Ltd. | Method of manufacturing solid dispersion |
| JP2516524B2 (ja) * | 1992-04-27 | 1996-07-24 | 大洋薬品工業株式会社 | 持続性製剤 |
| JPH07159587A (ja) | 1993-12-07 | 1995-06-23 | Hitachi Ltd | 樹脂性能モニタ |
| JPH07187998A (ja) * | 1993-12-27 | 1995-07-25 | Kao Corp | 錠剤の製造方法 |
| GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
| US5895790A (en) | 1995-03-14 | 1999-04-20 | Good; Elmer | Thermosetting wide range polymer blends |
| DE19531067A1 (de) | 1995-08-23 | 1997-02-27 | Hermann P T Prof Dr Med Ammon | Verwendung von Boswelliasäure und ihren Derivaten zur Hemmung der normalen und gesteigerten Leukozytenelastase- oder Plasminaktivität |
| DK0904060T3 (da) * | 1996-05-20 | 2004-04-13 | Janssen Pharmaceutica Nv | Antifungale præparater med forbedret biotilgængelighed |
| UY26615A1 (es) | 2000-03-16 | 2001-10-25 | Pfizer Prod Inc | Inhibidor de la glucogeno fosforilasa. |
| US6709146B1 (en) | 2000-07-28 | 2004-03-23 | David Little | Thermokinetic mixer and method of using |
| JP4547148B2 (ja) * | 2001-06-22 | 2010-09-22 | ベンド・リサーチ・インコーポレーテッド | 非晶質薬剤の吸着物の医薬組成物 |
| KR20040011248A (ko) | 2002-07-30 | 2004-02-05 | 환인제약 주식회사 | 암로디핀의 고체분산체와 그 제조방법 및 그를 포함하는약학적 조성물 |
| CN101091695B (zh) | 2003-02-03 | 2011-01-19 | 诺瓦提斯公司 | 药物制剂 |
| GB0319797D0 (en) * | 2003-08-26 | 2003-09-24 | Leuven K U Res & Dev | Particle size reduction of poorly soluble drugs |
| US20050158376A1 (en) * | 2003-10-23 | 2005-07-21 | Sardi William F. | Dietary supplement and method of processing same |
| CN101664411A (zh) * | 2003-11-14 | 2010-03-10 | 味之素株式会社 | 苯丙氨酸衍生物的固体分散体或固体分散体医药制剂 |
| WO2005053851A1 (en) | 2003-11-26 | 2005-06-16 | E.I. Dupont De Nemours And Company | High pressure media milling system and process of milling particles |
| JP2005263758A (ja) * | 2004-03-22 | 2005-09-29 | Kirin Brewery Co Ltd | 非晶質のn−{2−クロロ−4−[(6,7−ジメトキシ−4−キナゾリニル)オキシ]フェニル}−n’−プロピルウレア |
| KR101086254B1 (ko) * | 2004-11-04 | 2011-11-24 | 에스케이케미칼주식회사 | 생체이용률이 개선된 프란루카스트 고체분산체 조성물 및그 고체분산체의 제조방법 |
| EP1865929A2 (en) | 2005-03-28 | 2007-12-19 | Bioresponse, L.L.C. | Diindolylmethane-based compositions and methods of use thereof for promoting oral mucosal and bone health |
| JP2006347939A (ja) * | 2005-06-15 | 2006-12-28 | Tokyo Printing Ink Mfg Co Ltd | 薬物高分子複合体の製造方法及び薬物高分子複合体 |
| JP4429262B2 (ja) * | 2005-12-09 | 2010-03-10 | 壽製薬株式会社 | フェノフィブラートの固体分散体 |
| US9545361B1 (en) * | 2011-07-25 | 2017-01-17 | Dispersol Technologies, Llc | Multiple speed process for preserving heat sensitive portions of a thermokinetically melt blended batch |
| WO2009026461A2 (en) | 2007-08-21 | 2009-02-26 | Board Of Regents, The University Of Texas System | Thermo-kinetic mixing for pharmaceutical applications |
| JP2012047227A (ja) | 2010-08-25 | 2012-03-08 | Nippon Steel & Sumikin Metal Products Co Ltd | ナット保持部材 |
| US20140039031A1 (en) | 2011-02-23 | 2014-02-06 | Dispersol Technologies. LLC | Pharmaceutical formulations of acetyl-11-keto-b-boswellic acid, diindolylmethane, and curcumin for pharmaceutical applications |
| US20170333404A1 (en) | 2014-11-03 | 2017-11-23 | Dispersol Technologies, Llc | Improved formulations of vemurafenib and methods of making the same |
-
2008
- 2008-08-21 WO PCT/US2008/073913 patent/WO2009026461A2/en not_active Ceased
- 2008-08-21 CN CN2008801123533A patent/CN101835492B/zh active Active
- 2008-08-21 CA CA3076115A patent/CA3076115C/en active Active
- 2008-08-21 EP EP08798412A patent/EP2187968A4/en not_active Ceased
- 2008-08-21 JP JP2010522038A patent/JP6073043B2/ja active Active
- 2008-08-21 CA CA2697099A patent/CA2697099C/en active Active
- 2008-08-21 US US12/196,154 patent/US8486423B2/en active Active
- 2008-08-21 CA CA2990445A patent/CA2990445C/en active Active
-
2013
- 2013-07-15 US US13/942,199 patent/US9339440B2/en active Active
-
2014
- 2014-07-22 JP JP2014148568A patent/JP2014221816A/ja not_active Withdrawn
-
2016
- 2016-04-06 JP JP2016076558A patent/JP2016121195A/ja not_active Withdrawn
- 2016-05-13 US US15/154,083 patent/US10022385B2/en active Active
-
2018
- 2018-06-19 US US16/012,025 patent/US10668085B2/en active Active
- 2018-12-03 JP JP2018226362A patent/JP2019052173A/ja not_active Withdrawn
-
2020
- 2020-05-05 US US16/866,676 patent/US11439650B2/en active Active
-
2022
- 2022-07-25 US US17/814,567 patent/US12023343B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2491918C2 (ru) | Способ грануляции из расплава | |
| EP2755637B1 (en) | Solid dispersion of poorly soluble compounds comprising crospovidone and at least one water-soluble polymer | |
| JP6730315B2 (ja) | 担体ポリマーとしてのポリビニルアルコールを用いた化合物の固体分散体 | |
| JP5443344B2 (ja) | タダラフィルを含む薬剤の製造の方法 | |
| JP7458440B2 (ja) | 改善された薬物製剤 | |
| JP2010500411A (ja) | 高結晶性治療化合物の固体分散体を製造するための方法 | |
| WO2016111725A1 (en) | Dosage form incorporating an amorphous dgug solid solution | |
| JP2018517734A5 (enExample) | ||
| JP2022177014A (ja) | Hcvを処置するための固体医薬組成物 | |
| EP2701689B1 (en) | Pharmaceutical compositions of raltegravir, methods of preparation and use thereof | |
| JP7472199B2 (ja) | Hcvを処置するための固体医薬組成物 | |
| JP7378393B2 (ja) | 改善された薬物製剤 | |
| JP2017513878A (ja) | 活性成分(i)含有組成物及びその製造方法 | |
| EP3256105A1 (en) | Method of producing a granulated composition | |
| JP6823002B2 (ja) | ヒプロメロース酢酸エステルコハク酸エステルを含む射出成型用組成物及びその製造方法 | |
| HK40000762A (en) | Improved drug formulations | |
| TW201605437A (zh) | 固態醫藥組合物 |