JP2013539974A5 - - Google Patents

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JP2013539974A5
JP2013539974A5 JP2013530817A JP2013530817A JP2013539974A5 JP 2013539974 A5 JP2013539974 A5 JP 2013539974A5 JP 2013530817 A JP2013530817 A JP 2013530817A JP 2013530817 A JP2013530817 A JP 2013530817A JP 2013539974 A5 JP2013539974 A5 JP 2013539974A5
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mannose
glycoprotein
disease
mannosidase
cell
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JP2013530817A
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JP2013539974A (ja
JP6151183B2 (ja
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Priority claimed from PCT/IB2011/002770 external-priority patent/WO2012042386A2/en
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Publication of JP2013539974A5 publication Critical patent/JP2013539974A5/ja
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JP2013530817A 2010-09-29 2011-09-29 マンノース−1−ホスホ−6−マンノース結合からキャップを外すことおよびリン酸化n−グリカンを脱マンノシル化することができるマンノシダーゼならびに哺乳動物細胞による糖タンパク質の取り込みを促進する方法 Expired - Fee Related JP6151183B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38794010P 2010-09-29 2010-09-29
US61/387,940 2010-09-29
US201161477014P 2011-04-19 2011-04-19
US61/477,014 2011-04-19
PCT/IB2011/002770 WO2012042386A2 (en) 2010-09-29 2011-09-29 Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated n-glycans and methods of facilitating mammalian cellular uptake of glycoproteins

Publications (3)

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JP2013539974A JP2013539974A (ja) 2013-10-31
JP2013539974A5 true JP2013539974A5 (https=) 2014-11-13
JP6151183B2 JP6151183B2 (ja) 2017-06-21

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JP2013530817A Expired - Fee Related JP6151183B2 (ja) 2010-09-29 2011-09-29 マンノース−1−ホスホ−6−マンノース結合からキャップを外すことおよびリン酸化n−グリカンを脱マンノシル化することができるマンノシダーゼならびに哺乳動物細胞による糖タンパク質の取り込みを促進する方法

Country Status (9)

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US (2) US9347050B2 (https=)
EP (1) EP2622088A2 (https=)
JP (1) JP6151183B2 (https=)
KR (1) KR101983572B1 (https=)
CN (1) CN103328646B (https=)
BR (1) BR112013007616B1 (https=)
CA (1) CA2812870C (https=)
SG (1) SG189108A1 (https=)
WO (1) WO2012042386A2 (https=)

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CA2812872C (en) 2010-09-29 2021-08-03 Oxyrane Uk Limited De-mannosylation of phosphorylated n-glycans
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