JP6151183B2 - マンノース−１−ホスホ−６−マンノース結合からキャップを外すことおよびリン酸化ｎ−グリカンを脱マンノシル化することができるマンノシダーゼならびに哺乳動物細胞による糖タンパク質の取り込みを促進する方法 - Google Patents

マンノース−１−ホスホ−６−マンノース結合からキャップを外すことおよびリン酸化ｎ−グリカンを脱マンノシル化することができるマンノシダーゼならびに哺乳動物細胞による糖タンパク質の取り込みを促進する方法 Download PDF

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JP6151183B2
JP6151183B2 JP2013530817A JP2013530817A JP6151183B2 JP 6151183 B2 JP6151183 B2 JP 6151183B2 JP 2013530817 A JP2013530817 A JP 2013530817A JP 2013530817 A JP2013530817 A JP 2013530817A JP 6151183 B2 JP6151183 B2 JP 6151183B2
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mannose
disease
mannosidase
glycoprotein
cell
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JP2013539974A (ja
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カトレーン カミラ テレスポレ アリダ マリア ピーンス，
カトレーン カミラ テレスポレ アリダ マリア ピーンス，
ヴァウテル フェルフェケン，
ヴァウテル フェルフェケン，
アルベナ ヴェルギリエヴァ ヴァレフスカ，
アルベナ ヴェルギリエヴァ ヴァレフスカ，
グヴェンダ ノエラ ペネルト，
グヴェンダ ノエラ ペネルト，
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オキシレイン ユーケー リミテッド
オキシレイン ユーケー リミテッド
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2013530817A 2010-09-29 2011-09-29 マンノース−１−ホスホ−６−マンノース結合からキャップを外すことおよびリン酸化ｎ−グリカンを脱マンノシル化することができるマンノシダーゼならびに哺乳動物細胞による糖タンパク質の取り込みを促進する方法 Expired - Fee Related JP6151183B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38794010P 2010-09-29 2010-09-29
US61/387,940 2010-09-29
US201161477014P 2011-04-19 2011-04-19
US61/477,014 2011-04-19
PCT/IB2011/002770 WO2012042386A2 (en) 2010-09-29 2011-09-29 Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated n-glycans and methods of facilitating mammalian cellular uptake of glycoproteins

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JP2013539974A JP2013539974A (ja) 2013-10-31
JP2013539974A5 JP2013539974A5 (https=) 2014-11-13
JP6151183B2 true JP6151183B2 (ja) 2017-06-21

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JP2013530817A Expired - Fee Related JP6151183B2 (ja) 2010-09-29 2011-09-29 マンノース−１−ホスホ−６−マンノース結合からキャップを外すことおよびリン酸化ｎ−グリカンを脱マンノシル化することができるマンノシダーゼならびに哺乳動物細胞による糖タンパク質の取り込みを促進する方法

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US (2) US9347050B2 (https=)
EP (1) EP2622088A2 (https=)
JP (1) JP6151183B2 (https=)
KR (1) KR101983572B1 (https=)
CN (1) CN103328646B (https=)
BR (1) BR112013007616B1 (https=)
CA (1) CA2812870C (https=)
SG (1) SG189108A1 (https=)
WO (1) WO2012042386A2 (https=)

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US20160251693A1 (en) 2016-09-01
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CA2812870A1 (en) 2012-04-05
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US20130267473A1 (en) 2013-10-10
SG189108A1 (en) 2013-05-31
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