JP2013539960A - 工業規模の散布のためのバイオマトリックス足場 - Google Patents
工業規模の散布のためのバイオマトリックス足場 Download PDFInfo
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- JP2013539960A JP2013539960A JP2013518763A JP2013518763A JP2013539960A JP 2013539960 A JP2013539960 A JP 2013539960A JP 2013518763 A JP2013518763 A JP 2013518763A JP 2013518763 A JP2013518763 A JP 2013518763A JP 2013539960 A JP2013539960 A JP 2013539960A
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- Prior art keywords
- biomatrix
- tissue
- cells
- liver
- scaffold
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- C—CHEMISTRY; METALLURGY
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
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- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/28—Materials or treatment for tissue regeneration for liver reconstruction
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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- C12N2710/20011—Papillomaviridae
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- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24223—Virus like particles [VLP]
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- C12N2770/00011—Details
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- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24251—Methods of production or purification of viral material
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Prostheses (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36093910P | 2010-07-02 | 2010-07-02 | |
| US61/360,939 | 2010-07-02 | ||
| PCT/US2011/042825 WO2012003463A1 (en) | 2010-07-02 | 2011-07-01 | Biomatrix scaffolds for industrial scale dispersal |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016237355A Division JP2017055764A (ja) | 2010-07-02 | 2016-12-07 | 工業規模の散布のためのバイオマトリックス足場 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2013539960A true JP2013539960A (ja) | 2013-10-31 |
Family
ID=45402468
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013518763A Pending JP2013539960A (ja) | 2010-07-02 | 2011-07-01 | 工業規模の散布のためのバイオマトリックス足場 |
| JP2013518758A Expired - Fee Related JP6308781B2 (ja) | 2010-07-02 | 2011-07-01 | バイオマトリックス足場 |
| JP2016237356A Expired - Fee Related JP6612722B2 (ja) | 2010-07-02 | 2016-12-07 | バイオマトリックス足場 |
| JP2016237355A Pending JP2017055764A (ja) | 2010-07-02 | 2016-12-07 | 工業規模の散布のためのバイオマトリックス足場 |
| JP2018102418A Expired - Fee Related JP6527272B2 (ja) | 2010-07-02 | 2018-05-29 | 工業規模の散布のためのバイオマトリックス足場 |
| JP2018193545A Pending JP2019017392A (ja) | 2010-07-02 | 2018-10-12 | 工業規模の散布のためのバイオマトリックス足場 |
| JP2018193565A Pending JP2019017393A (ja) | 2010-07-02 | 2018-10-12 | バイオマトリックス足場 |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013518758A Expired - Fee Related JP6308781B2 (ja) | 2010-07-02 | 2011-07-01 | バイオマトリックス足場 |
| JP2016237356A Expired - Fee Related JP6612722B2 (ja) | 2010-07-02 | 2016-12-07 | バイオマトリックス足場 |
| JP2016237355A Pending JP2017055764A (ja) | 2010-07-02 | 2016-12-07 | 工業規模の散布のためのバイオマトリックス足場 |
| JP2018102418A Expired - Fee Related JP6527272B2 (ja) | 2010-07-02 | 2018-05-29 | 工業規模の散布のためのバイオマトリックス足場 |
| JP2018193545A Pending JP2019017392A (ja) | 2010-07-02 | 2018-10-12 | 工業規模の散布のためのバイオマトリックス足場 |
| JP2018193565A Pending JP2019017393A (ja) | 2010-07-02 | 2018-10-12 | バイオマトリックス足場 |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US8802081B2 (enExample) |
| EP (6) | EP2588027B8 (enExample) |
| JP (7) | JP2013539960A (enExample) |
| CN (4) | CN105713868A (enExample) |
| DK (2) | DK2588027T3 (enExample) |
| ES (6) | ES2946590T3 (enExample) |
| HU (2) | HUE032727T2 (enExample) |
| LT (2) | LT2588027T (enExample) |
| PL (2) | PL2588083T3 (enExample) |
| PT (2) | PT2588083T (enExample) |
| WO (2) | WO2012003450A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020501137A (ja) * | 2016-11-30 | 2020-01-16 | ブルーカー ダルトニック ゲーエムベーハー | 質量分析測定および評価のための微生物試料および微生物の調製 |
| JP2021523242A (ja) * | 2018-05-14 | 2021-09-02 | ルースターバイオ, インコーポレイテッドRoosterbio, Inc. | 細胞の高張液に由来する細胞外物質に関連する方法及び組成物 |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2946590T3 (es) * | 2010-07-02 | 2023-07-21 | Univ North Carolina Chapel Hill | Andamios de biomatriz para dispersión a escala industrial |
| NL2009145C2 (en) * | 2012-07-06 | 2014-01-07 | Xeltis B V | Implant. |
| CN103536967B (zh) * | 2012-07-10 | 2016-04-13 | 上海微创医疗器械(集团)有限公司 | 一种制备细胞外基质支架材料的脱细胞方法 |
| US9533013B2 (en) | 2013-03-13 | 2017-01-03 | University Of North Carolina At Chapel Hill | Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree |
| CN105164250A (zh) | 2013-03-15 | 2015-12-16 | 米罗马特里克斯医疗公司 | 灌注脱细胞化的肝脏在胰岛细胞再细胞化中的用途 |
| DK2968418T3 (da) * | 2013-03-15 | 2024-01-15 | Nutech Medical Inc | Præparater afledt af placentamaterialer til fremstilling og anvendelse deraf |
| HUE042704T2 (hu) * | 2013-04-08 | 2019-07-29 | Regentys Corp | Eljárás és készítmény gyulladásos bélbetegség kezelésére kolektómia nélkül |
| MX2016001247A (es) | 2013-07-30 | 2016-08-17 | Musculoskeletal Transplant Foundation | Matrices derivadas de tejido suave acelular y metodos para preparar las mismas. |
| CN103432627B (zh) * | 2013-08-26 | 2015-03-25 | 北京瑞健高科生物科技有限公司 | 一种制备动物脱细胞组织基质材料的方法及其制备的组织基质材料 |
| CA2944181C (en) | 2014-03-27 | 2019-09-17 | Salk Institute For Biological Studies | Compositions and methods for treating type 1 and type 2 diabetes and related disorders |
| GB201409858D0 (en) * | 2014-06-03 | 2014-07-16 | Ucl Business Plc | Human liver scaffolds |
| CN104288837B (zh) * | 2014-09-11 | 2016-04-13 | 杨淑珍 | 一种脱细胞真皮基质及其制备方法和用途 |
| EP3262157A4 (en) | 2015-02-27 | 2018-12-05 | Salk Institute for Biological Studies | Reprogramming progenitor compositions and methods of use therefore |
| CN104928241B (zh) * | 2015-03-27 | 2018-04-13 | 北京康爱瑞浩生物科技股份有限公司 | 一种增强型nk细胞的活化方法及细胞制备方法 |
| US10683484B2 (en) * | 2015-06-12 | 2020-06-16 | National University Of Singapore | Derivation of hepatic stem cells and mature liver cell types and uses thereof |
| US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| CN106884002B (zh) * | 2015-12-15 | 2021-03-19 | 上海市针灸经络研究所 | 一种稳定的结肠上皮细胞培养方法 |
| CN105833353B (zh) * | 2016-05-09 | 2018-04-20 | 拜欧迪赛尔(北京)生物科技有限公司 | 一种生物工程脱细胞真皮基质的制备及用途 |
| US20170369849A1 (en) * | 2016-05-11 | 2017-12-28 | The University Of North Carolina At Chapel Hill | Compositions and methods for bioengineered tissues |
| EP3936610A1 (en) | 2016-05-25 | 2022-01-12 | Salk Institute for Biological Studies | Compositions and methods for organoid generation and disease modeling |
| CA3030166A1 (en) * | 2016-07-12 | 2018-01-18 | The University Of North Carolina At Chapel Hill | Biomatrix scaffolds for use in diagnosing and modeling cancer |
| CN106362212A (zh) * | 2016-10-21 | 2017-02-01 | 华中科技大学同济医学院附属协和医院 | 一种用于去除组织细胞的亲脂性去细胞溶液、试剂盒和方法 |
| GB2555787A (en) * | 2016-11-07 | 2018-05-16 | Landberg Goran | Diagnostic methods |
| CA3066710A1 (en) * | 2017-06-12 | 2018-12-20 | The University Of North Carolina At Chapel Hill | Patch graft compositions for cell engraftment |
| JP2020529267A (ja) * | 2017-07-31 | 2020-10-08 | ドゥ カント ザゴ, アレシャンドリDO CANTO ZAGO, Alexandre | 迅速なストラットの被覆および血管内皮の被覆を促進するためのデバイスおよび方法 |
| EP3470096A1 (en) * | 2017-10-13 | 2019-04-17 | Erasmus University Medical Center Rotterdam | Elastin reduction allowing recellularization of cartilage implants |
| WO2019129646A1 (en) * | 2017-12-29 | 2019-07-04 | F. Hoffmann-La Roche Ag | Tissue sample preparation system |
| WO2019241499A1 (en) | 2018-06-13 | 2019-12-19 | Miromatrix Medical Inc. | Fistula filler and deployment system |
| CN108753686B (zh) * | 2018-06-22 | 2021-06-22 | 中国人民解放军军事科学院军事医学研究院 | 组织工程肝脏模型、其构建方法及其应用 |
| CN108753687B (zh) * | 2018-06-22 | 2021-04-16 | 中国人民解放军军事科学院军事医学研究院 | 微肝组织培养模型、其构建方法及其应用 |
| CN109735490A (zh) * | 2019-03-06 | 2019-05-10 | 福建省海西细胞生物工程有限公司 | 一种脂肪干细胞提取方法 |
| CN110257335B (zh) * | 2019-04-10 | 2020-09-29 | 首都医科大学附属北京天坛医院 | 单层或多层的3d脑胶质瘤细胞培养模型及其构建方法和应用 |
| JP7547383B2 (ja) | 2019-05-16 | 2024-09-09 | レスメド・プロプライエタリー・リミテッド | 医療デバイスにおける双方向通信 |
| WO2021045373A1 (ko) * | 2019-09-04 | 2021-03-11 | 한국생명공학연구원 | 증식 가능한 간 오가노이드 |
| CN110559485B (zh) * | 2019-09-25 | 2021-02-02 | 北京大清生物技术股份有限公司 | 一种生物组织基质材料及其制备方法与应用 |
| DE102019130568A1 (de) | 2019-11-13 | 2021-05-20 | Aesculap Ag | Chirurgischer Fräser mit verbesserter Spanabfuhr |
| CN111110919A (zh) * | 2019-12-30 | 2020-05-08 | 广东泓志生物科技有限公司 | 大网膜脱细胞基质材料的制备方法及软骨组织的构建方法 |
| JP7623017B2 (ja) * | 2020-02-14 | 2025-01-28 | セルアートジェン インコーポレイテッド | 臓器オルガノイドの培養及び移植のための脱細胞臓器組織由来の支持体及びその製造方法 |
| CN111760072B (zh) * | 2020-08-24 | 2022-09-23 | 鲁峰 | 脂肪来源的真皮内填充物及其制备和应用 |
| CN114748208B (zh) * | 2022-04-15 | 2024-01-12 | 柔脉医疗(深圳)有限公司 | 一种可原位检测多种化学、生物成分的组织工程支架 |
| CN115948331B (zh) * | 2022-10-17 | 2024-10-22 | 中国人民解放军西部战区总医院 | 一种从小鼠胆囊中分离获取间充质干细胞的方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020115208A1 (en) * | 2000-08-16 | 2002-08-22 | Shannon Mitchell | Decellularized tissue engineered constructs and tissues |
| WO2010039823A2 (en) * | 2008-09-30 | 2010-04-08 | The Regents Of The University Of California | Compositions and methods for tissue repair with extracellular matrices |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19569C (de) | ANNA ERBER in Brieg | Neuerungen an der unter Nr. 17581 patentirten Handlaterne | ||
| CA2155186A1 (en) | 1993-02-01 | 1994-08-18 | Kevin M. Ulmer | Methods and apparatus for dna sequencing |
| US5695998A (en) * | 1995-02-10 | 1997-12-09 | Purdue Research Foundation | Submucosa as a growth substrate for islet cells |
| US6149891A (en) * | 1995-05-31 | 2000-11-21 | Israel Humanitarian Foundation Ltd. | X-ray contrast medium and method for protecting against harmful effects thereof |
| US20020177551A1 (en) | 2000-05-31 | 2002-11-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| AU2002243980B2 (en) * | 2001-02-14 | 2007-08-23 | Robert J. Hariri | Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells |
| EP1404388B1 (en) | 2001-06-28 | 2013-10-23 | Cook Biotech, Inc. | Graft prosthesis devices containing renal capsule collagen |
| US20040187877A1 (en) * | 2002-12-04 | 2004-09-30 | Badylak Stephen F. | Method for repair of liver tissue |
| CN100412188C (zh) * | 2003-02-21 | 2008-08-20 | Uab研究基金会 | 生物活性天然生物基质组合物 |
| WO2005002601A1 (en) | 2003-06-25 | 2005-01-13 | Badylak Stephen F | Conditioned matrix compositions for tissue restoration |
| AU2004252568B2 (en) * | 2003-06-27 | 2011-06-30 | Ethicon, Incorporated | Regeneration and repair of neural tissue using postpartum-derived cells |
| MX2007015541A (es) * | 2005-06-10 | 2008-03-06 | Celgene Corp | Composiciones de colageno de placenta humana proceso para su preparacion, metodos de uso y equipos que contienen las composiciones. |
| WO2007018165A1 (ja) * | 2005-08-10 | 2007-02-15 | Toray Industries, Inc. | スポンジ状構造体および粉末、ならびにそれらの製造方法 |
| US9944900B2 (en) | 2006-01-18 | 2018-04-17 | Hemacell Perfusion | Pulsatile perfusion extraction method for non-embryonic pluripotent stem cells |
| US8241908B2 (en) * | 2006-05-16 | 2012-08-14 | Becton, Dickinson And Company | Extracellular matrix coated surface for culturing cells |
| US8685107B2 (en) | 2007-07-03 | 2014-04-01 | Histogenics Corporation | Double-structured tissue implant and a method for preparation and use thereof |
| US20120064050A1 (en) * | 2009-02-04 | 2012-03-15 | Yale University | Tissue Engineering of Lung |
| US9277999B2 (en) * | 2009-02-27 | 2016-03-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Joint bioscaffolds |
| ES2650450T3 (es) * | 2010-06-30 | 2018-01-18 | Miromatrix Medical Inc. | Uso de órganos descelularizados por perfusión para recelularización adaptada |
| ES2946590T3 (es) * | 2010-07-02 | 2023-07-21 | Univ North Carolina Chapel Hill | Andamios de biomatriz para dispersión a escala industrial |
-
2011
- 2011-07-01 ES ES19199017T patent/ES2946590T3/es active Active
- 2011-07-01 EP EP11801504.9A patent/EP2588027B8/en not_active Not-in-force
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- 2011-07-01 EP EP16191501.2A patent/EP3192862B1/en active Active
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- 2011-07-01 WO PCT/US2011/042825 patent/WO2012003463A1/en not_active Ceased
- 2011-07-01 ES ES16191506T patent/ES2791312T3/es active Active
-
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- 2014-08-08 US US14/455,819 patent/US20150110753A1/en not_active Abandoned
-
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- 2015-10-13 US US14/813,993 patent/US9944896B2/en active Active
-
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- 2016-07-27 US US15/221,413 patent/US10246678B2/en active Active
- 2016-12-07 JP JP2016237356A patent/JP6612722B2/ja not_active Expired - Fee Related
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-
2018
- 2018-04-12 US US15/952,094 patent/US10640747B2/en not_active Expired - Fee Related
- 2018-05-29 JP JP2018102418A patent/JP6527272B2/ja not_active Expired - Fee Related
- 2018-10-12 JP JP2018193545A patent/JP2019017392A/ja active Pending
- 2018-10-12 JP JP2018193565A patent/JP2019017393A/ja active Pending
-
2019
- 2019-02-12 US US16/274,020 patent/US20200002667A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020115208A1 (en) * | 2000-08-16 | 2002-08-22 | Shannon Mitchell | Decellularized tissue engineered constructs and tissues |
| WO2010039823A2 (en) * | 2008-09-30 | 2010-04-08 | The Regents Of The University Of California | Compositions and methods for tissue repair with extracellular matrices |
Non-Patent Citations (4)
| Title |
|---|
| BIOMATERIALS,2009 JUL,30(21),P.3513-22,EPUB 2009 MAR 25, JPN6015031408, ISSN: 0003130051 * |
| J AM SOC NEPHROL.,2009 NOV,20(11),P.2338-47,EPUB 2009 SEP 3, JPN6015031401, ISSN: 0003130049 * |
| NAT MED.,2010 JUL,16(7),P.814-20,EPUB 2010 JUN 13, JPN6015031411, ISSN: 0003130052 * |
| ORGANOGENESIS,2010 APR-JUN,6(2),P.134-6, JPN6015031403, ISSN: 0003130050 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020501137A (ja) * | 2016-11-30 | 2020-01-16 | ブルーカー ダルトニック ゲーエムベーハー | 質量分析測定および評価のための微生物試料および微生物の調製 |
| US11480579B2 (en) | 2016-11-30 | 2022-10-25 | Bruker Daltonik Gmbh | Preparing live microbial samples and microorganisms for subsequent mass spectrometric measurement and evaluation |
| JP2021523242A (ja) * | 2018-05-14 | 2021-09-02 | ルースターバイオ, インコーポレイテッドRoosterbio, Inc. | 細胞の高張液に由来する細胞外物質に関連する方法及び組成物 |
| JP7554484B2 (ja) | 2018-05-14 | 2024-09-20 | ルースターバイオ,インコーポレイテッド | 細胞の高張液に由来する細胞外物質に関連する方法及び組成物 |
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