DK2588027T3 - Biomatrix scaffolds for industrial scale distribution - Google Patents

Biomatrix scaffolds for industrial scale distribution Download PDF

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Publication number
DK2588027T3
DK2588027T3 DK11801504.9T DK11801504T DK2588027T3 DK 2588027 T3 DK2588027 T3 DK 2588027T3 DK 11801504 T DK11801504 T DK 11801504T DK 2588027 T3 DK2588027 T3 DK 2588027T3
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biomatrix
cells
tissue
medium
scaffold
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DK11801504.9T
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Danish (da)
English (en)
Inventor
Marsha Lynn Roach
Richard Harold Malavarca
Yunfang Wang
Lola Cynthia Mcadams Reid
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Univ North Carolina Chapel Hill
Marsha Lynn Roach
Richard Harold Malavarca
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Application filed by Univ North Carolina Chapel Hill, Marsha Lynn Roach, Richard Harold Malavarca filed Critical Univ North Carolina Chapel Hill
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
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    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
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  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Prostheses (AREA)
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DK11801504.9T 2010-07-02 2011-07-01 Biomatrix scaffolds for industrial scale distribution DK2588027T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36093910P 2010-07-02 2010-07-02
PCT/US2011/042825 WO2012003463A1 (en) 2010-07-02 2011-07-01 Biomatrix scaffolds for industrial scale dispersal

Publications (1)

Publication Number Publication Date
DK2588027T3 true DK2588027T3 (en) 2017-06-19

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Application Number Title Priority Date Filing Date
DK11801504.9T DK2588027T3 (en) 2010-07-02 2011-07-01 Biomatrix scaffolds for industrial scale distribution
DK11801493.5T DK2588083T3 (en) 2010-07-02 2011-07-01 Biomatrixscaffolds

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Application Number Title Priority Date Filing Date
DK11801493.5T DK2588083T3 (en) 2010-07-02 2011-07-01 Biomatrixscaffolds

Country Status (11)

Country Link
US (7) US8802081B2 (enExample)
EP (6) EP2588027B8 (enExample)
JP (7) JP2013539960A (enExample)
CN (4) CN105713868A (enExample)
DK (2) DK2588027T3 (enExample)
ES (6) ES2946590T3 (enExample)
HU (2) HUE032727T2 (enExample)
LT (2) LT2588027T (enExample)
PL (2) PL2588083T3 (enExample)
PT (2) PT2588083T (enExample)
WO (2) WO2012003450A2 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
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ES2946590T3 (es) * 2010-07-02 2023-07-21 Univ North Carolina Chapel Hill Andamios de biomatriz para dispersión a escala industrial
NL2009145C2 (en) * 2012-07-06 2014-01-07 Xeltis B V Implant.
CN103536967B (zh) * 2012-07-10 2016-04-13 上海微创医疗器械（集团）有限公司 一种制备细胞外基质支架材料的脱细胞方法
US9533013B2 (en) 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
CN105164250A (zh) 2013-03-15 2015-12-16 米罗马特里克斯医疗公司 灌注脱细胞化的肝脏在胰岛细胞再细胞化中的用途
DK2968418T3 (da) * 2013-03-15 2024-01-15 Nutech Medical Inc Præparater afledt af placentamaterialer til fremstilling og anvendelse deraf
HUE042704T2 (hu) * 2013-04-08 2019-07-29 Regentys Corp Eljárás és készítmény gyulladásos bélbetegség kezelésére kolektómia nélkül
MX2016001247A (es) 2013-07-30 2016-08-17 Musculoskeletal Transplant Foundation Matrices derivadas de tejido suave acelular y metodos para preparar las mismas.
CN103432627B (zh) * 2013-08-26 2015-03-25 北京瑞健高科生物科技有限公司 一种制备动物脱细胞组织基质材料的方法及其制备的组织基质材料
CA2944181C (en) 2014-03-27 2019-09-17 Salk Institute For Biological Studies Compositions and methods for treating type 1 and type 2 diabetes and related disorders
GB201409858D0 (en) * 2014-06-03 2014-07-16 Ucl Business Plc Human liver scaffolds
CN104288837B (zh) * 2014-09-11 2016-04-13 杨淑珍 一种脱细胞真皮基质及其制备方法和用途
EP3262157A4 (en) 2015-02-27 2018-12-05 Salk Institute for Biological Studies Reprogramming progenitor compositions and methods of use therefore
CN104928241B (zh) * 2015-03-27 2018-04-13 北京康爱瑞浩生物科技股份有限公司 一种增强型nk细胞的活化方法及细胞制备方法
US10683484B2 (en) * 2015-06-12 2020-06-16 National University Of Singapore Derivation of hepatic stem cells and mature liver cell types and uses thereof
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
CN106884002B (zh) * 2015-12-15 2021-03-19 上海市针灸经络研究所 一种稳定的结肠上皮细胞培养方法
CN105833353B (zh) * 2016-05-09 2018-04-20 拜欧迪赛尔（北京）生物科技有限公司 一种生物工程脱细胞真皮基质的制备及用途
US20170369849A1 (en) * 2016-05-11 2017-12-28 The University Of North Carolina At Chapel Hill Compositions and methods for bioengineered tissues
EP3936610A1 (en) 2016-05-25 2022-01-12 Salk Institute for Biological Studies Compositions and methods for organoid generation and disease modeling
CA3030166A1 (en) * 2016-07-12 2018-01-18 The University Of North Carolina At Chapel Hill Biomatrix scaffolds for use in diagnosing and modeling cancer
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