JP2013531031A5 - - Google Patents

Download PDF

Info

Publication number
JP2013531031A5
JP2013531031A5 JP2013519189A JP2013519189A JP2013531031A5 JP 2013531031 A5 JP2013531031 A5 JP 2013531031A5 JP 2013519189 A JP2013519189 A JP 2013519189A JP 2013519189 A JP2013519189 A JP 2013519189A JP 2013531031 A5 JP2013531031 A5 JP 2013531031A5
Authority
JP
Japan
Prior art keywords
linked
optionally substituted
pharmaceutically acceptable
heteroaryl
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013519189A
Other languages
English (en)
Japanese (ja)
Other versions
JP5830534B2 (ja
JP2013531031A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2011/052974 external-priority patent/WO2012004743A1/en
Publication of JP2013531031A publication Critical patent/JP2013531031A/ja
Publication of JP2013531031A5 publication Critical patent/JP2013531031A5/ja
Application granted granted Critical
Publication of JP5830534B2 publication Critical patent/JP5830534B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013519189A 2010-07-09 2011-07-05 化合物 Expired - Fee Related JP5830534B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36292710P 2010-07-09 2010-07-09
US61/362,927 2010-07-09
US201161492525P 2011-06-02 2011-06-02
US61/492,525 2011-06-02
PCT/IB2011/052974 WO2012004743A1 (en) 2010-07-09 2011-07-05 Benzenesulfonamides useful as sodium channel inhibitors

Publications (3)

Publication Number Publication Date
JP2013531031A JP2013531031A (ja) 2013-08-01
JP2013531031A5 true JP2013531031A5 (OSRAM) 2014-07-31
JP5830534B2 JP5830534B2 (ja) 2015-12-09

Family

ID=45439019

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013519189A Expired - Fee Related JP5830534B2 (ja) 2010-07-09 2011-07-05 化合物

Country Status (8)

Country Link
US (1) US8772293B2 (OSRAM)
EP (1) EP2590951B1 (OSRAM)
JP (1) JP5830534B2 (OSRAM)
AR (1) AR082201A1 (OSRAM)
CA (1) CA2804593C (OSRAM)
ES (1) ES2533065T3 (OSRAM)
UY (1) UY33491A (OSRAM)
WO (1) WO2012004743A1 (OSRAM)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2803118C (en) 2010-07-09 2015-11-03 Pfizer Limited Sulfonamide derivatives as nav 1.7 inhibitors
JP5872552B2 (ja) 2010-07-09 2016-03-01 ファイザー・リミテッドPfizer Limited 化学化合物
US9102621B2 (en) 2010-07-12 2015-08-11 Pfizer Limited Acyl sulfonamide compounds
CA2804716A1 (en) 2010-07-12 2012-01-19 Pfizer Limited Chemical compounds
JP2013536165A (ja) 2010-07-12 2013-09-19 ファイザー・リミテッド 痛みの処置のためのnav1.7阻害薬としてのスルホンアミド誘導体
EP2593432B1 (en) 2010-07-12 2014-10-22 Pfizer Limited N-sulfonylbenzamide derivatives useful as voltage gated sodium channel inhibitors
US8772343B2 (en) 2010-07-12 2014-07-08 Pfizer Limited Chemical compounds
CA2855019A1 (en) * 2011-10-31 2013-05-10 Xenon Pharmaceuticals Inc. Biaryl ether sulfonamides and their use as therapeutic agents
CA2853439A1 (en) 2011-10-31 2013-05-10 Xenon Pharmaceuticals Inc. Benzenesulfonamide compounds and their use as therapeutic agents
US8889741B2 (en) * 2012-02-09 2014-11-18 Daiichi Sankyo Company, Limited Cycloalkane derivatives
JPWO2013137371A1 (ja) * 2012-03-15 2015-08-03 興和株式会社 新規ピリミジン化合物及びそれらを含有する医薬
WO2013161928A1 (ja) * 2012-04-26 2013-10-31 塩野義製薬株式会社 オキサゾロトリアゾール誘導体およびそれらを含有する医薬組成物
WO2013177224A1 (en) 2012-05-22 2013-11-28 Genentech, Inc. N-substituted benzamides and their use in the treatment of pain
BR112015000187A2 (pt) 2012-07-06 2017-06-27 Genentech Inc benzamidas substituídas com n e métodos de uso das mesmas
JP6251275B2 (ja) * 2012-10-15 2017-12-20 デウン ファーマシューティカル カンパニー リミテッド ナトリウムチャンネル阻害剤、その製造方法およびその用途
US9388179B2 (en) 2012-10-26 2016-07-12 Merck Sharp & Dohme Corp. N-substituted indazole sulfonamide compounds with selective activity in voltage-gated sodium channels
BR112015022488A2 (pt) 2013-03-14 2017-07-18 Genentech Inc triazolopiridinas substituídas e métodos de uso das mesmas
ES2687481T3 (es) * 2013-03-15 2018-10-25 Chromocell Corporation Moduladores del canal de sodio para el tratamiento del dolor
EP2970156B1 (en) 2013-03-15 2018-07-25 Genentech, Inc. Substituted benzoxazoles and methods of use thereof
TW201443025A (zh) 2013-04-19 2014-11-16 Pfizer Ltd 化學化合物
TW201512171A (zh) 2013-04-19 2015-04-01 Pfizer Ltd 化學化合物
KR20160054570A (ko) * 2013-09-10 2016-05-16 크로모셀 코포레이션 통증과 당뇨병의 치료를 위한 나트륨 통로 조절인자
JP6383418B2 (ja) 2013-11-27 2018-08-29 ジェネンテック, インコーポレイテッド 置換ベンズアミド及びその使用方法
US10468036B2 (en) * 2014-04-30 2019-11-05 Accusonus, Inc. Methods and systems for processing and mixing signals using signal decomposition
EP3148992A1 (en) 2014-05-30 2017-04-05 Pfizer Inc. Benzenesulfonamides useful as sodium channel inhibitors
EP3166939B1 (en) 2014-07-07 2019-06-05 Genentech, Inc. Therapeutic compounds and methods of use thereof
WO2016034971A1 (en) 2014-09-04 2016-03-10 Pfizer Limited Sulfonamides derivatives as urat1 inhibitors
CR20170591A (es) 2015-05-22 2018-05-07 Genentech Inc Benzamidas sustituidas y métodos para utilizarlas
EP3341353A1 (en) 2015-08-27 2018-07-04 Genentech, Inc. Therapeutic compounds and methods of use thereof
PE20181003A1 (es) 2015-09-28 2018-06-26 Genentech Inc Compuestos terapeuticos y sus metodos de uso
CA3002920A1 (en) 2015-11-06 2017-05-11 Daiichi Sankyo Company, Limited Method for removing dimethoxybenzyl group
WO2017091592A1 (en) 2015-11-25 2017-06-01 Genentech, Inc. Substituted benzamides useful as sodium channel blockers
EA201891313A1 (ru) 2015-12-18 2018-11-30 Мерк Шарп И Доум Корп. Замещенные гидроксиалкиламинами и гидроксициклоалкиламинами соединения диаминарилсульфонамидов с избирательной активностью в потенциалзависимых натриевых каналах
EP3436432B1 (en) 2016-03-30 2021-01-27 Genentech, Inc. Substituted benzamides and methods of use thereof
AU2017268006B2 (en) 2016-05-20 2021-03-11 Xenon Pharmaceuticals Inc. Benzenesulfonamide compounds and their use as therapeutic agents
MA46546A (fr) 2016-10-17 2021-05-05 Genentech Inc Composés thérapeutiques et leurs procédés d'utilisation
RU2760303C2 (ru) 2016-12-09 2021-11-23 Ксенон Фармасьютикалз Инк. Соединения бензолсульфонамидов и их использование в качестве терапевтических средств
EP3601273B1 (en) 2017-03-24 2021-12-01 Genentech, Inc. 4-piperidin-n-(pyrimidin-4-yl)chroman-7-sulfonamide derivatives as sodium channel inhibitors
WO2019165290A1 (en) 2018-02-26 2019-08-29 Genentech, Inc. Pyridine-sulfonamide compounds and their use against pain and related conditions
CN111936494A (zh) 2018-03-30 2020-11-13 豪夫迈·罗氏有限公司 作为钠通道抑制剂的取代的氢-吡啶并-吖嗪
TW202003490A (zh) 2018-05-22 2020-01-16 瑞士商赫孚孟拉羅股份公司 治療性化合物及其使用方法
JP7371029B2 (ja) 2018-06-13 2023-10-30 ゼノン・ファーマシューティカルズ・インコーポレイテッド ベンゼンスルホンアミド化合物および治療剤としてのその使用
JP7383012B2 (ja) 2018-08-31 2023-11-17 ゼノン・ファーマシューティカルズ・インコーポレイテッド ヘテロアリール置換スルホンアミド化合物、およびナトリウムチャネル阻害剤としてのその使用
EA202190395A1 (ru) 2018-08-31 2021-06-15 Ксенон Фармасьютикалз Инк. Замещенные гетероарилом сульфонамидные соединения и их применение в качестве терапевтических средств
WO2020117626A1 (en) 2018-12-05 2020-06-11 Merck Sharp & Dohme Corp. 4-amino or 4-alkoxy-substituted aryl sulfonamide compounds with selective activity in voltage-gated sodium channels
TW202216671A (zh) * 2020-06-25 2022-05-01 瑞士商諾華公司 1,4—二取代的嗒𠯤化合物之製造方法
AU2022417384A1 (en) * 2021-12-23 2024-07-11 Veralox Therapeutics Inc. Compositions and methods of use to treat 12-lipoxygenase (12-lox) mediated diseases
WO2025160284A1 (en) * 2024-01-23 2025-07-31 The Board Of Trustees Of The University Of Illinois Algorithm for computer-assisted molecular modularization

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR71915B (OSRAM) 1979-11-27 1983-08-16 Pfizer
EP0194599A3 (en) 1985-03-14 1988-01-20 Nissan Chemical Industries Ltd. Benzamide derivatives, process for producing the same, and soil fungicides containing the same
JPH02500271A (ja) 1986-08-20 1990-02-01 エフ エム シー コーポレーション 除草剤
US5084085A (en) 1986-08-20 1992-01-28 Fmc Corporation Herbicidal aryloxyphenyltriazolinones and related compounds
US4845264A (en) 1987-03-05 1989-07-04 Teijin Limited Phenoxycarboxylic acid and herbicide comprising it as active ingredient
US4920132A (en) 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920130A (en) 1987-11-02 1990-04-24 Rorer Pharamceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920133A (en) 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920131A (en) 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
EP0325245B1 (en) 1988-01-19 1993-10-20 Tanabe Seiyaku Co., Ltd. Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use
GB8911854D0 (en) 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
HUT54991A (en) 1989-08-11 1991-04-29 Ici Plc Process for producing quinoline derivatives and pharmaceutical compositions comprising such compounds
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
GB2244054B (en) 1990-04-19 1994-04-06 Ici Plc Pyridine derivatives
WO1993000332A1 (en) 1991-06-25 1993-01-07 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
GB2266527A (en) 1992-03-17 1993-11-03 Merck & Co Inc Substituted azetidinones useful in the treatment of leukemia
JPH05289262A (ja) 1992-04-10 1993-11-05 Fuji Photo Film Co Ltd ハロゲン化銀カラー写真感光材料
JPH05307242A (ja) 1992-04-28 1993-11-19 Fuji Photo Film Co Ltd ハロゲン化銀カラー写真感光材料
JP3101848B2 (ja) 1992-05-15 2000-10-23 富士写真フイルム株式会社 ハロゲン化銀カラー写真感光材料
FR2694295B1 (fr) 1992-07-28 1994-09-02 Adir Nouveaux peptides dérivés de trifluoromethylcetones, leur procéde de préparation et les compositions pharmaceutiques qui les contiennent.
AU5802894A (en) 1992-12-17 1994-07-04 Merck & Co., Inc. New substituted azetidinones as anti-inflammatory and antidegenerative agents
WO1996004905A1 (en) 1994-08-08 1996-02-22 Merck & Co., Inc. Phenoxyphenylacetic acid derivatives
PT617001E (pt) 1993-03-19 2000-06-30 Merck & Co Inc Derivados do acido fenoxifenilacetico
JPH06347968A (ja) 1993-04-14 1994-12-22 Fuji Photo Film Co Ltd ハロゲン化銀感光材料
DK77393D0 (da) 1993-06-29 1993-06-29 Novo Nordisk As Aktivering af enzymer
JP3503839B2 (ja) 1994-05-25 2004-03-08 富士写真フイルム株式会社 ポジ型感光性組成物
AU3642795A (en) 1994-09-27 1996-04-19 Merck & Co., Inc. Endothelin receptor antagonists for the treatment of emesis
US5593994A (en) 1994-09-29 1997-01-14 The Dupont Merck Pharmaceutical Company Prostaglandin synthase inhibitors
GB9514031D0 (en) 1995-07-10 1995-09-06 Zeneca Ltd Chemical process
GB9518953D0 (en) 1995-09-15 1995-11-15 Pfizer Ltd Pharmaceutical formulations
JP3519218B2 (ja) 1996-08-14 2004-04-12 富士写真フイルム株式会社 ハロゲン化銀写真感光材料および画像形成方法
WO2000035296A1 (en) 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Improved release of medicament active agents from a chewing gum coating
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
EP0995742A4 (en) 1997-06-27 2004-08-25 Fujisawa Pharmaceutical Co SULPHONAMIDE COMPOUNDS AND THEIR MEDICAL USE
US6555584B1 (en) 2000-06-29 2003-04-29 Ajinomoto Co., Inc. Acylsulfonamide derivative
DE19742951A1 (de) 1997-09-29 1999-04-15 Hoechst Schering Agrevo Gmbh Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
PL344977A1 (en) 1997-10-17 2001-11-19 Aventis Pharm Prod Inc Therapeutic uses of quinoline derivatives
ES2234169T3 (es) 1997-12-23 2005-06-16 Warner-Lambert Company Llc Compuestos de tiourea, composiciones y procedimientos de tratamiento o prevencion de enfermedades inflamatorias y ateroesclerosis.
GB9805520D0 (en) 1998-03-17 1998-05-13 Zeneca Ltd Chemical compounds
GT199900044A (es) 1998-04-10 2000-09-14 Procedimientos para preparar haluros de fenoxifenilsulfonilo.
DE19851184A1 (de) 1998-11-06 2000-05-11 Aventis Pharma Gmbh N-Arylsulfonyl-aminosäure-omega-amide
GB9828442D0 (en) 1998-12-24 1999-02-17 Karobio Ab Novel thyroid receptor ligands and method II
NZ515087A (en) 1999-04-28 2003-11-28 Aventis Pharma Gmbh Tri-aryl acid derivatives as PPAR receptor ligands
ES2226839T3 (es) 1999-05-05 2005-04-01 MERCK & CO., INC. Nuevos catecoles como agentes antimicrobianos.
WO2000071512A1 (en) 1999-05-24 2000-11-30 Cor Therapeutics, Inc. INHIBITORS OF FACTOR Xa
AU5283900A (en) 1999-05-24 2000-12-12 Cor Therapeutics, Inc. Inhibitors of factor xa
AU5283800A (en) 1999-05-24 2000-12-12 Cor Therapeutics, Inc. Inhibitors of factor xa
JP2001075213A (ja) 1999-09-07 2001-03-23 Fuji Photo Film Co Ltd ハロゲン化銀写真乳剤、その製造方法及びこれを用いたハロゲン化銀写真感光材料
WO2001023347A1 (en) 1999-09-29 2001-04-05 Novo Nordisk A/S Novel aromatic compounds
HK1047577B (zh) 1999-10-13 2005-09-16 辉瑞产品公司 用作一元胺重摄取抑制剂的联芳醚衍生物
GB9927056D0 (en) 1999-11-17 2000-01-12 Karobio Ab Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders
MXPA02007603A (es) 2000-03-09 2003-02-24 Aventis Pharma Gmbh Usos terapeuticos de mediadores ppar.
US6720338B2 (en) 2000-09-20 2004-04-13 Abbott Laboratories N-acylsulfonamide apoptosis promoters
AR031130A1 (es) 2000-09-20 2003-09-10 Abbott Lab N-acilsulfonamidas promotoras de la apoptosis
EP1260221A3 (en) 2001-05-23 2002-12-18 Pfizer Products Inc. Combination treatment for depression and anxiety
SE0101978D0 (sv) 2001-06-01 2001-06-01 Astrazeneca Ab New compounds
CN1602291B (zh) 2001-11-16 2010-05-12 富山化学工业株式会社 新二苯甲酮衍生物或其盐
WO2004018386A2 (en) 2002-08-26 2004-03-04 Merck & Co., Inc. Acetophenone potentiators of metabotropic glutamate receptors
EP1558245A2 (en) 2002-10-28 2005-08-03 Novo Nordisk A/S Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases
AU2004218412A1 (en) 2003-02-28 2004-09-16 Oxigene, Inc. Compositions and methods with enhanced therapeutic activity
AU2004263179B8 (en) 2003-08-08 2011-07-14 Vertex Pharmaceuticals Incorporated Heteroarylaminosulfonylphenyl derivatives for use as sodium or calcium channel blockers in the treatment of pain
CA2551909C (en) 2004-02-12 2011-10-11 Transtech Pharma, Inc. Substituted azole derivatives, compositions, and methods of use
GB0405033D0 (en) 2004-03-05 2004-04-07 Karobio Ab Novel pharmaceutical compositions
CA2564355C (en) 2004-05-07 2012-07-03 Amgen Inc. Protein kinase modulators and method of use
AU2005267883A1 (en) 2004-07-30 2006-02-09 Merck & Co., Inc. Indanone potentiators of metabotropic glutamate receptors
CA2582247C (en) 2004-10-20 2014-02-11 Applied Research Systems Ars Holding N.V. 3-arylamino pyridine derivatives
JP2008189549A (ja) 2005-05-12 2008-08-21 Astellas Pharma Inc カルボン酸誘導体またはその塩
ES2380683T3 (es) 2005-12-15 2012-05-17 Astrazeneca Ab Difenil-éteres, -amidas, -sulfuros y - metanos sustituidos para el tratamiento de la enfermedad respiratoria
JP2009057282A (ja) 2005-12-19 2009-03-19 Astellas Pharma Inc カルボン酸誘導体又はその塩
WO2007115410A1 (en) 2006-04-10 2007-10-18 Painceptor Pharma Corporation Compositions and methods for modulating gated ion channels
EP1894928A1 (en) 2006-08-29 2008-03-05 PheneX Pharmaceuticals AG Heterocyclic fxr binding compounds
SI2076508T1 (sl) 2006-10-18 2011-04-29 Pfizer Prod Inc Spojine biaril eter sečnine
KR101444489B1 (ko) 2007-02-01 2014-09-24 리스버로직스 코퍼레이션 심혈관 질환을 예방 및 치료하기 위한 화합물
DE602008000809D1 (de) 2007-03-23 2010-04-29 Icagen Inc Ionenkanal-Hemmer
AU2008247102B2 (en) 2007-05-03 2011-11-24 Pfizer Limited 2 -pyridine carboxamide derivatives as sodium channel modulators
EP2154130A4 (en) 2007-06-07 2011-09-07 Astellas Pharma Inc pyridone
CA2693588C (en) 2007-07-13 2015-11-17 Icagen, Inc. Sodium channel inhibitors
CN101855210A (zh) 2007-10-11 2010-10-06 沃泰克斯药物股份有限公司 用作电压-门控钠通道抑制剂的酰胺类
UY31468A1 (es) 2007-11-15 2009-07-17 Derivados bis-(sulfonilamino) en terapia 065
TW200930369A (en) 2007-11-15 2009-07-16 Astrazeneca Ab Bis-(sulfonylamino) derivatives in therapy
WO2009067541A2 (en) 2007-11-20 2009-05-28 Gilead Sciences, Inc. Integrase inhibitors
EP2222639A1 (en) 2007-11-21 2010-09-01 Decode Genetics EHF Biaryl pde4 inhibitors for treating pulmonary and cardiovascular disorders
GB0725214D0 (en) 2007-12-24 2008-02-06 Karobio Ab Pharmaceutical compounds
EP2252590A1 (en) 2008-02-15 2010-11-24 Basf Se Substituted sulfonic acid amide compounds
EP2119690A1 (en) 2008-05-14 2009-11-18 Academisch Medisch Centrum bij de Universiteit van Amsterdam Radiolabelled MMP selective compounds
WO2009144159A1 (en) 2008-05-28 2009-12-03 Basf Se Substituted pyridin-4-yl-methyl sulfonamidesas fungicides
JP5304785B2 (ja) 2008-06-23 2013-10-02 アステラス製薬株式会社 スルホンアミド化合物又はその塩
US8107894B2 (en) 2008-08-12 2012-01-31 Raytheon Company Modular solid-state millimeter wave (MMW) RF power source
NZ593473A (en) 2009-01-12 2013-02-22 Pfizer Ltd Sulfonamide derivatives
JP5289262B2 (ja) 2009-09-30 2013-09-11 京セラドキュメントソリューションズ株式会社 シート搬送装置とこれを備えた画像読取装置及び画像形成装置
CA2803118C (en) * 2010-07-09 2015-11-03 Pfizer Limited Sulfonamide derivatives as nav 1.7 inhibitors
JP5872552B2 (ja) * 2010-07-09 2016-03-01 ファイザー・リミテッドPfizer Limited 化学化合物
EP2593432B1 (en) 2010-07-12 2014-10-22 Pfizer Limited N-sulfonylbenzamide derivatives useful as voltage gated sodium channel inhibitors
US8772343B2 (en) 2010-07-12 2014-07-08 Pfizer Limited Chemical compounds
CA2804716A1 (en) 2010-07-12 2012-01-19 Pfizer Limited Chemical compounds
US9102621B2 (en) 2010-07-12 2015-08-11 Pfizer Limited Acyl sulfonamide compounds
JP2013536165A (ja) 2010-07-12 2013-09-19 ファイザー・リミテッド 痛みの処置のためのnav1.7阻害薬としてのスルホンアミド誘導体

Similar Documents

Publication Publication Date Title
JP2013531031A5 (OSRAM)
JP2013531029A5 (OSRAM)
JP2015501833A5 (OSRAM)
JP2016506960A5 (OSRAM)
JP2016040288A5 (OSRAM)
RU2015143843A (ru) Ингибиторы гистондеацетилазы
JP2016528301A5 (OSRAM)
RU2016105581A (ru) Способ лечения острого, хронического и подострого кашля и непреодолимого желания откашляться
JP2015535277A5 (OSRAM)
JP2019509276A5 (OSRAM)
JP2013537203A5 (OSRAM)
TN2012000608A1 (en) Imidazopyridine derivatives, process for the preparation thereof and therapeutic use thereof
JP2016536364A5 (OSRAM)
JP2006524660A5 (OSRAM)
TN2012000609A1 (en) Indolizine derivatives, process for the preparation thereof and therapeutic use thereof
RU2015120216A (ru) Ингибиторы тирозинкиназы брутона
JP2013544276A5 (OSRAM)
JP2015500843A5 (OSRAM)
JP2011521911A5 (OSRAM)
JP2016518437A5 (OSRAM)
JP2013542261A5 (OSRAM)
NZ588830A (en) Inhibitors of protein kinases
JP2016506962A5 (OSRAM)
JP2015504081A5 (OSRAM)
JP2013533883A5 (OSRAM)