JP2013529077A5 - - Google Patents
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- Publication number
- JP2013529077A5 JP2013529077A5 JP2013510352A JP2013510352A JP2013529077A5 JP 2013529077 A5 JP2013529077 A5 JP 2013529077A5 JP 2013510352 A JP2013510352 A JP 2013510352A JP 2013510352 A JP2013510352 A JP 2013510352A JP 2013529077 A5 JP2013529077 A5 JP 2013529077A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- borrelia
- nucleic acid
- amino acid
- nucleotide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33490110P | 2010-05-14 | 2010-05-14 | |
| US61/334,901 | 2010-05-14 | ||
| PCT/US2011/036525 WO2011143617A1 (en) | 2010-05-14 | 2011-05-13 | Chimeric ospa genes, proteins, and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016126631A Division JP2016171816A (ja) | 2010-05-14 | 2016-06-27 | Ospaキメラおよびそのワクチンでの使用法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013529077A JP2013529077A (ja) | 2013-07-18 |
| JP2013529077A5 true JP2013529077A5 (enExample) | 2014-06-26 |
| JP6030052B2 JP6030052B2 (ja) | 2016-11-24 |
Family
ID=44121257
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013510352A Expired - Fee Related JP6030052B2 (ja) | 2010-05-14 | 2011-05-13 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2013510354A Expired - Fee Related JP6227407B2 (ja) | 2010-05-14 | 2011-05-13 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2016126631A Pending JP2016171816A (ja) | 2010-05-14 | 2016-06-27 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2016126608A Withdrawn JP2016168057A (ja) | 2010-05-14 | 2016-06-27 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2018129896A Withdrawn JP2018150386A (ja) | 2010-05-14 | 2018-07-09 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2020135857A Expired - Fee Related JP6965417B2 (ja) | 2010-05-14 | 2020-08-11 | Ospaキメラおよびそのワクチンでの使用法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013510354A Expired - Fee Related JP6227407B2 (ja) | 2010-05-14 | 2011-05-13 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2016126631A Pending JP2016171816A (ja) | 2010-05-14 | 2016-06-27 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2016126608A Withdrawn JP2016168057A (ja) | 2010-05-14 | 2016-06-27 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2018129896A Withdrawn JP2018150386A (ja) | 2010-05-14 | 2018-07-09 | Ospaキメラおよびそのワクチンでの使用法 |
| JP2020135857A Expired - Fee Related JP6965417B2 (ja) | 2010-05-14 | 2020-08-11 | Ospaキメラおよびそのワクチンでの使用法 |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US8623375B2 (enExample) |
| EP (4) | EP2569008B1 (enExample) |
| JP (6) | JP6030052B2 (enExample) |
| KR (7) | KR20130062954A (enExample) |
| CN (3) | CN103108652B (enExample) |
| AU (2) | AU2011252850B2 (enExample) |
| BR (2) | BR112012027315B1 (enExample) |
| CA (2) | CA2799181C (enExample) |
| MX (3) | MX348113B (enExample) |
| PL (2) | PL2569009T3 (enExample) |
| RU (2) | RU2636455C2 (enExample) |
| SI (2) | SI2569008T1 (enExample) |
| WO (2) | WO2011143617A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8623375B2 (en) | 2010-05-14 | 2014-01-07 | Baxter International Inc. | Chimeric OspA genes, proteins, and methods of use thereof |
| US20120215701A1 (en) | 2010-10-20 | 2012-08-23 | Mehta Kaushal N | Flexible monetization service apparatuses, methods and systems |
| US10438176B2 (en) | 2011-07-17 | 2019-10-08 | Visa International Service Association | Multiple merchant payment processor platform apparatuses, methods and systems |
| US10318941B2 (en) | 2011-12-13 | 2019-06-11 | Visa International Service Association | Payment platform interface widget generation apparatuses, methods and systems |
| US10096022B2 (en) * | 2011-12-13 | 2018-10-09 | Visa International Service Association | Dynamic widget generator apparatuses, methods and systems |
| US8986704B2 (en) * | 2012-07-06 | 2015-03-24 | Valneva Austria Gmbh | Mutant fragments of OspA and methods and uses relating thereto |
| WO2014018274A1 (en) * | 2012-07-27 | 2014-01-30 | Baxter International, Inc. | Compositions comprising chimeric ospa molecules and methods of use thereof |
| PL223175B1 (pl) | 2012-10-22 | 2016-10-31 | Inst Chemii Bioorganicznej Polskiej Akademii Nauk | Szczepionka przeciw boreliozie, konstrukt genetyczny, rekombinowane białko, sposób otrzymywania konstruktu genetycznego, sposób otrzymywania szczepionki, sposób otrzymywania rekombinowanych białek, zastosowanie rekombinowanych białek do wytwarzania szczepionki przeciwko boreliozie |
| WO2014144521A1 (en) * | 2013-03-15 | 2014-09-18 | The Regents Of The University Of California | Mitochondrial-derived peptide mots3 regulates metabolism and cell survival |
| US20160213766A1 (en) * | 2013-09-23 | 2016-07-28 | Ventria Bioscience, Inc. | OspA Fusion Protein for Vaccination against Lyme Disease |
| MX369195B (es) | 2014-01-09 | 2019-10-31 | Valneva Austria Gmbh | Fragmentos mutantes de ospa y métodos y usos relacionados con estos. |
| CZ2014320A3 (cs) * | 2014-05-09 | 2015-11-18 | VÝZKUMNÝ ÚSTAV VETERINÁRNÍHO LÉKAŘSTVÍ, v.v.i. | Polyepitopový antigen, vakcinační konstrukt a vakcína pro prevenci lymeské boreliózy |
| EP3180024B1 (en) | 2014-08-11 | 2022-05-18 | University of Massachusetts | Anti-ospa antibodies and methods of use |
| US11216468B2 (en) | 2015-02-08 | 2022-01-04 | Visa International Service Association | Converged merchant processing apparatuses, methods and systems |
| WO2017029000A1 (en) * | 2015-08-14 | 2017-02-23 | Telefonaktiebolaget Lm Ericsson (Publ) | A node and method for managing a packet data network connection |
| EP3534941A4 (en) * | 2016-11-07 | 2020-07-08 | The Wistar Institute Of Anatomy And Biology | CONSTRUCTIONS OF ANTI-DNA ANTIBODIES FOR USE AGAINST LYME DISEASE |
| WO2018189372A1 (en) * | 2017-04-13 | 2018-10-18 | Valneva Austria Gmbh | Multivalent ospa polypeptides and methods and uses relating thereto |
| JP7614841B2 (ja) | 2018-04-03 | 2025-01-16 | サノフイ | 抗原性呼吸器合胞体ウイルスポリペプチド |
| EP3773698A1 (en) | 2018-04-03 | 2021-02-17 | Sanofi | Ferritin proteins |
| CN112584858A (zh) * | 2018-04-03 | 2021-03-30 | 赛诺菲 | 抗原性ospa多肽 |
| CN112512566A (zh) | 2018-04-03 | 2021-03-16 | 赛诺菲 | 抗原性爱泼斯坦-巴尔病毒多肽 |
| CN110483624B (zh) * | 2019-08-22 | 2021-02-09 | 中国疾病预防控制中心传染病预防控制所 | 伽氏疏螺旋体OspA蛋白C端肽段及其应用 |
| CN111196842A (zh) * | 2020-01-09 | 2020-05-26 | 济南大学 | 一种外膜转运通道蛋白的非跨膜结构域的表达纯化方法 |
| US20240026412A1 (en) | 2020-04-09 | 2024-01-25 | Valneva Austria Gmbh | Improved methods of producing a lipidated protein |
| IL297166A (en) * | 2020-04-09 | 2022-12-01 | Valneva Austria Gmbh | Compositions comprising three ospa fusion proteins for medical use |
| EP4262860A4 (en) | 2020-12-17 | 2025-11-12 | Idexx Lab Inc | DETECTION AND TREATMENT OF ROCKY MOUNTAIN SPRINKLE FEVER |
| WO2022261050A1 (en) * | 2021-06-07 | 2022-12-15 | The University Of Massachusetts | Apparatus and method for continuous production of rna |
| EP4490042A4 (en) | 2022-03-08 | 2026-03-04 | Equashield Medical Ltd | FLUID TRANSFER STATION IN A ROBOTIC PHARMACEUTICAL PREPARATION SYSTEM |
| JP2026525284A (ja) | 2023-07-10 | 2026-07-29 | ダイナヴァックス テクノロジーズ コーポレイション | アジュバントおよびborrelia細胞表層タンパク質a抗原を含むライム病ワクチン |
| EP4743110A1 (en) | 2023-07-10 | 2026-05-20 | Dynavax Technologies Corporation | Lyme disease vaccines containing an adjuvant and Borrelia outer surface protein A and C antigens |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK590288D0 (da) | 1988-10-24 | 1988-10-24 | Symbicom Ab | Kemiske forbindelser |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DE3572982D1 (en) | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
| SE8405493D0 (sv) | 1984-11-01 | 1984-11-01 | Bror Morein | Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel |
| US4877612A (en) | 1985-05-20 | 1989-10-31 | Frank M. Berger | Immunological adjuvant and process for preparing the same, pharmaceutical compositions, and process |
| DE3521994A1 (de) | 1985-06-20 | 1987-01-02 | Bayer Ag | N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| ES2039229T3 (es) | 1986-01-14 | 1993-09-16 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Procedimiento para la preparacion de complejos inmunogenicos y composiciones farmaceuticas que contienen estos complejos. |
| US4806352A (en) | 1986-04-15 | 1989-02-21 | Ribi Immunochem Research Inc. | Immunological lipid emulsion adjuvant |
| US4830885A (en) | 1987-06-08 | 1989-05-16 | Allied-Signal Inc. | Chlorine-resistant semipermeable membranes |
| US7094391B1 (en) | 1988-10-24 | 2006-08-22 | The University Of Texas System | Compositions and methods for administering Borrelia burgdorferi antigens |
| US5777095A (en) | 1988-10-24 | 1998-07-07 | Symbicom Aktiebolag | Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90 |
| US6143872A (en) * | 1988-10-24 | 2000-11-07 | Symbicom Aktiebolag | Borrelia burdorferi Osp A and B proteins and immunogenic peptides |
| EP0401384B1 (en) | 1988-12-22 | 1996-03-13 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| SG122738A1 (en) * | 1990-06-15 | 2006-06-29 | Univ Yale | Compositions and methods for the prevention and diagnosis of lyme disease |
| US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| FI933580L (fi) | 1991-02-15 | 1993-10-13 | Uab Research Foundation | Strukturgen av pneumokockprotein |
| US6676942B1 (en) | 1991-08-15 | 2004-01-13 | Smithkline Beecham Biologicals (S.A.) | Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines |
| US6113914A (en) | 1991-08-15 | 2000-09-05 | Smithkline Beecham Biologicals (S.A.) | Osp A proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines |
| US5234784A (en) | 1992-04-01 | 1993-08-10 | Eastman Kodak Company | Method of making a projection viewable transparency comprising an electrostatographic toner image |
| WO2002016422A2 (en) * | 2000-08-18 | 2002-02-28 | Research Foundation Of The State University Of New York | Recombinant constructs of borrelia burgdorferi |
| US7008625B2 (en) | 1993-11-01 | 2006-03-07 | Research Foundation Of The State University Of New York | Recombinant constructs of Borrelia burgdorferi |
| US6248562B1 (en) | 1993-11-01 | 2001-06-19 | Research Foundation State University Of New York | Chimeric proteins comprising borrelia polypeptides and uses therefor |
| DE69433690T2 (de) | 1993-11-01 | 2005-03-10 | Brookhaven Science Associates | Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür |
| CA2244110A1 (en) | 1996-02-12 | 1997-08-14 | Cobra Therapeutics Limited | Novel methods of vaccination and vaccines thereof comprising a nucleic acid encoding a first epitope and a peptide containing a second epitope |
| US6368603B1 (en) * | 1997-03-05 | 2002-04-09 | Merial Limited | Lyme combination compositions and uses |
| WO1999000413A1 (en) * | 1997-06-30 | 1999-01-07 | The Administrators Of The Tulane Educational Fund | Surface antigens and proteins useful in compositions for the diagnosis and prevention of lyme disease |
| US6342220B1 (en) | 1997-08-25 | 2002-01-29 | Genentech, Inc. | Agonist antibodies |
| GB9726555D0 (en) | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Vaccine |
| US6541011B2 (en) * | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| GB9811219D0 (en) | 1998-05-26 | 1998-07-22 | Smithkline Beecham Biolog | Novel process |
| EP1939294A1 (en) * | 2000-08-18 | 2008-07-02 | Research Foundation Of State University Of New York | Recombinant constructs of borrelia burgdorferi |
| EP1311540B1 (en) | 2000-08-18 | 2007-12-19 | Research Foundation Of State University Of New York | Altered ospa of borrelia burgdorferi |
| CN100351265C (zh) | 2003-04-02 | 2007-11-28 | 美国政府健康及人类服务部 | 含胆固醇的化合物以及其用作针对伯氏疏螺旋体(Borrelia burgdorferi)的免疫原的应用 |
| BRPI0409459A (pt) * | 2003-04-16 | 2006-05-02 | Wyeth Corp | novas composições imunogênicas para a prevenção e tratamento de doença meningocócica |
| ATE466022T1 (de) * | 2004-03-24 | 2010-05-15 | Merck Sharp & Dohme | Optimierte expression von hpv-52-l1 in hefe |
| EP1768688A4 (en) | 2004-07-02 | 2009-09-30 | Raymond J Dattwyler | ORAL BORRELIOSE VACCINE |
| GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| RU2008126239A (ru) * | 2005-11-29 | 2010-01-10 | Вирджиния Коммонвелт Юниверсити (Us) | Поливалентный химерный вакциноген и диагностический антиген ospc |
| AU2006320246A1 (en) | 2005-11-29 | 2007-06-07 | Virginia Commonwealth University | Polyvalent chimeric OspC vaccinogen and diagnostic antigen |
| EP2289906A1 (en) | 2006-09-15 | 2011-03-02 | Intercell AG | Borrelia antigens |
| ATE496935T1 (de) | 2007-02-22 | 2011-02-15 | Baxter Int | Verfahren zur aufreinigung hydrophober proteine |
| EA200901578A1 (ru) * | 2007-06-26 | 2010-08-30 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae |
| JP5788676B2 (ja) * | 2008-01-11 | 2015-10-07 | イノビオ ファーマシューティカルズ,インコーポレイティド | デングウイルスの複数のサブタイプに対する新規ワクチン |
| EP2274616A1 (en) | 2008-04-22 | 2011-01-19 | The Research Foundation of State University of New York | Borrelia burgdorferi cell envelope protein array |
| WO2009135118A2 (en) | 2008-05-02 | 2009-11-05 | Virginia Commonwealth University | Lyme disease vaccine |
| US8623375B2 (en) * | 2010-05-14 | 2014-01-07 | Baxter International Inc. | Chimeric OspA genes, proteins, and methods of use thereof |
| WO2014018274A1 (en) * | 2012-07-27 | 2014-01-30 | Baxter International, Inc. | Compositions comprising chimeric ospa molecules and methods of use thereof |
-
2011
- 2011-05-13 US US13/107,787 patent/US8623375B2/en not_active Expired - Fee Related
- 2011-05-13 MX MX2012013261A patent/MX348113B/es active IP Right Grant
- 2011-05-13 KR KR1020127032561A patent/KR20130062954A/ko not_active Ceased
- 2011-05-13 CN CN201180033687.3A patent/CN103108652B/zh not_active Expired - Fee Related
- 2011-05-13 EP EP11720967.6A patent/EP2569008B1/en active Active
- 2011-05-13 WO PCT/US2011/036525 patent/WO2011143617A1/en not_active Ceased
- 2011-05-13 KR KR1020207018904A patent/KR102230562B1/ko not_active Expired - Fee Related
- 2011-05-13 PL PL11722243T patent/PL2569009T3/pl unknown
- 2011-05-13 WO PCT/US2011/036533 patent/WO2011143623A1/en not_active Ceased
- 2011-05-13 SI SI201131835T patent/SI2569008T1/sl unknown
- 2011-05-13 RU RU2012153972A patent/RU2636455C2/ru active
- 2011-05-13 EP EP19201651.7A patent/EP3650041A1/en not_active Withdrawn
- 2011-05-13 EP EP11722243.0A patent/EP2569009B1/en active Active
- 2011-05-13 KR KR1020207005820A patent/KR102222869B1/ko not_active Expired - Fee Related
- 2011-05-13 MX MX2017006896A patent/MX375965B/es unknown
- 2011-05-13 MX MX2012013264A patent/MX340739B/es active IP Right Grant
- 2011-05-13 CN CN201710853809.2A patent/CN107641151B/zh not_active Expired - Fee Related
- 2011-05-13 AU AU2011252850A patent/AU2011252850B2/en not_active Ceased
- 2011-05-13 EP EP19217974.5A patent/EP3705133B1/en active Active
- 2011-05-13 CN CN201180033682.0A patent/CN103118701B/zh not_active Expired - Fee Related
- 2011-05-13 BR BR112012027315-9A patent/BR112012027315B1/pt not_active IP Right Cessation
- 2011-05-13 CA CA2799181A patent/CA2799181C/en active Active
- 2011-05-13 SI SI201131829T patent/SI2569009T1/sl unknown
- 2011-05-13 AU AU2011252844A patent/AU2011252844B2/en not_active Ceased
- 2011-05-13 CA CA2798331A patent/CA2798331C/en active Active
- 2011-05-13 KR KR1020127032560A patent/KR20130133120A/ko not_active Ceased
- 2011-05-13 BR BR112012029058-4A patent/BR112012029058B1/pt not_active IP Right Cessation
- 2011-05-13 PL PL11720967T patent/PL2569008T3/pl unknown
- 2011-05-13 JP JP2013510352A patent/JP6030052B2/ja not_active Expired - Fee Related
- 2011-05-13 JP JP2013510354A patent/JP6227407B2/ja not_active Expired - Fee Related
- 2011-05-13 KR KR1020187019612A patent/KR20180082633A/ko not_active Ceased
- 2011-05-13 KR KR1020197006820A patent/KR102130584B1/ko not_active Expired - Fee Related
- 2011-05-13 RU RU2012153752/10A patent/RU2583289C2/ru active
- 2011-05-13 KR KR1020187007814A patent/KR102085465B1/ko not_active Expired - Fee Related
- 2011-05-13 US US13/107,796 patent/US8623376B2/en not_active Expired - Fee Related
-
2013
- 2013-11-12 US US14/078,390 patent/US9303073B2/en active Active
- 2013-11-12 US US14/078,367 patent/US9334311B2/en active Active
-
2016
- 2016-02-22 US US15/049,438 patent/US9895434B2/en not_active Expired - Fee Related
- 2016-06-27 JP JP2016126631A patent/JP2016171816A/ja active Pending
- 2016-06-27 JP JP2016126608A patent/JP2016168057A/ja not_active Withdrawn
-
2018
- 2018-01-19 US US15/875,479 patent/US11305000B2/en not_active Expired - Fee Related
- 2018-07-09 JP JP2018129896A patent/JP2018150386A/ja not_active Withdrawn
-
2020
- 2020-08-11 JP JP2020135857A patent/JP6965417B2/ja not_active Expired - Fee Related
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