JP6227407B2 - Ｏｓｐａキメラおよびそのワクチンでの使用法 - Google Patents

Ｏｓｐａキメラおよびそのワクチンでの使用法 Download PDF

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Publication number
JP6227407B2
JP6227407B2 JP2013510354A JP2013510354A JP6227407B2 JP 6227407 B2 JP6227407 B2 JP 6227407B2 JP 2013510354 A JP2013510354 A JP 2013510354A JP 2013510354 A JP2013510354 A JP 2013510354A JP 6227407 B2 JP6227407 B2 JP 6227407B2
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Prior art keywords
seq
borrelia
polypeptide
amino acid
ospa
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2013510354A
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Japanese (ja)
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JP2013529078A5 (enExample
JP2013529078A (ja
Inventor
ブライアン エー． クロウ，
ブライアン エー． クロウ，
イアン リビー，
イアン リビー，
マリア オローケ，
マリア オローケ，
マイケル シュヴェンディンガー，
マイケル シュヴェンディンガー，
ジョン ジェイ． ダン，
ジョン ジェイ． ダン，
ベンジャミン ジェイ． ルフト，
ベンジャミン ジェイ． ルフト，
Original Assignee
バクスアルタ インコーポレイテッド
バクスアルタ インコーポレイテッド
バクスアルタ ゲーエムベーハー
バクスアルタ ゲーエムベーハー
ザ リサーチ ファウンデーション フォー ザ ステイト ユニバーシティー オブ ニューヨーク
ザ リサーチ ファウンデーション フォー ザ ステイト ユニバーシティー オブ ニューヨーク
ブルックヘイブン サイエンス アソシエイツ， エルエルシー
ブルックヘイブン サイエンス アソシエイツ， エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018—Lipids, e.g. in lipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2013510354A 2010-05-14 2011-05-13 Ｏｓｐａキメラおよびそのワクチンでの使用法 Expired - Fee Related JP6227407B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33490110P 2010-05-14 2010-05-14
US61/334,901 2010-05-14
PCT/US2011/036533 WO2011143623A1 (en) 2010-05-14 2011-05-13 Ospa chimeras and use thereof in vaccines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016126608A Division JP2016168057A (ja) 2010-05-14 2016-06-27 Ｏｓｐａキメラおよびそのワクチンでの使用法

Publications (3)

Publication Number Publication Date
JP2013529078A JP2013529078A (ja) 2013-07-18
JP2013529078A5 JP2013529078A5 (enExample) 2014-06-26
JP6227407B2 true JP6227407B2 (ja) 2017-11-08

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JP2013510354A Expired - Fee Related JP6227407B2 (ja) 2010-05-14 2011-05-13 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2013510352A Expired - Fee Related JP6030052B2 (ja) 2010-05-14 2011-05-13 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2016126608A Withdrawn JP2016168057A (ja) 2010-05-14 2016-06-27 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2016126631A Pending JP2016171816A (ja) 2010-05-14 2016-06-27 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2018129896A Withdrawn JP2018150386A (ja) 2010-05-14 2018-07-09 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2020135857A Expired - Fee Related JP6965417B2 (ja) 2010-05-14 2020-08-11 Ｏｓｐａキメラおよびそのワクチンでの使用法

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JP2013510352A Expired - Fee Related JP6030052B2 (ja) 2010-05-14 2011-05-13 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2016126608A Withdrawn JP2016168057A (ja) 2010-05-14 2016-06-27 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2016126631A Pending JP2016171816A (ja) 2010-05-14 2016-06-27 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2018129896A Withdrawn JP2018150386A (ja) 2010-05-14 2018-07-09 Ｏｓｐａキメラおよびそのワクチンでの使用法
JP2020135857A Expired - Fee Related JP6965417B2 (ja) 2010-05-14 2020-08-11 Ｏｓｐａキメラおよびそのワクチンでの使用法

Country Status (13)

Country Link
US (6) US8623375B2 (enExample)
EP (4) EP3650041A1 (enExample)
JP (6) JP6227407B2 (enExample)
KR (7) KR20180082633A (enExample)
CN (3) CN103108652B (enExample)
AU (2) AU2011252844B2 (enExample)
BR (2) BR112012029058B1 (enExample)
CA (2) CA2799181C (enExample)
MX (3) MX348113B (enExample)
PL (2) PL2569009T3 (enExample)
RU (2) RU2583289C2 (enExample)
SI (2) SI2569008T1 (enExample)
WO (2) WO2011143623A1 (enExample)

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