ATE263836T1 - Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür - Google Patents

Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür

Info

Publication number
ATE263836T1
ATE263836T1 AT95900453T AT95900453T ATE263836T1 AT E263836 T1 ATE263836 T1 AT E263836T1 AT 95900453 T AT95900453 T AT 95900453T AT 95900453 T AT95900453 T AT 95900453T AT E263836 T1 ATE263836 T1 AT E263836T1
Authority
AT
Austria
Prior art keywords
proteins
chimeric
chimere
proteins including
borrelia
Prior art date
Application number
AT95900453T
Other languages
English (en)
Inventor
John J Dunn
Benjamin J Luft
Original Assignee
Brookhaven Science Ass Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/235,836 external-priority patent/US6248562B1/en
Application filed by Brookhaven Science Ass Llc filed Critical Brookhaven Science Ass Llc
Application granted granted Critical
Publication of ATE263836T1 publication Critical patent/ATE263836T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT95900453T 1993-11-01 1994-10-27 Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür ATE263836T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14819193A 1993-11-01 1993-11-01
US08/235,836 US6248562B1 (en) 1993-11-01 1994-04-29 Chimeric proteins comprising borrelia polypeptides and uses therefor
PCT/US1994/012352 WO1995012676A1 (en) 1993-11-01 1994-10-27 Chimeric proteins comprising borrelia polypeptides: uses therefor

Publications (1)

Publication Number Publication Date
ATE263836T1 true ATE263836T1 (de) 2004-04-15

Family

ID=26845620

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95900453T ATE263836T1 (de) 1993-11-01 1994-10-27 Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür

Country Status (10)

Country Link
EP (1) EP0726955B1 (de)
AT (1) ATE263836T1 (de)
AU (1) AU8127494A (de)
CA (1) CA2175567C (de)
DE (1) DE69433690T2 (de)
DK (1) DK0726955T3 (de)
ES (1) ES2219657T3 (de)
IL (1) IL111479A0 (de)
PT (1) PT726955E (de)
WO (1) WO1995012676A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6676942B1 (en) * 1991-08-15 2004-01-13 Smithkline Beecham Biologicals (S.A.) Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines
WO2002016422A2 (en) * 2000-08-18 2002-02-28 Research Foundation Of The State University Of New York Recombinant constructs of borrelia burgdorferi
US7008625B2 (en) 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
CA2193870C (en) * 1995-12-25 2000-07-18 Nobuyuki Ise Treponema pallidum fused antigen and assay for anti-treponema pallidum antibodies using the same fused antigen
DE19632862B4 (de) * 1996-08-14 2006-08-03 Mikrogen Molekularbiologische Entwicklungs-Gmbh Immunologisch aktive Proteine von Borrelia burgdorferi, dafür kodierende Nukleinsäuren sowie deren Verwendung in Testkits und als Impfstoffe
EP1012269A2 (de) * 1997-09-10 2000-06-28 Symbicom Ab P13 antigenen von borrelia
DE19847142A1 (de) * 1998-10-13 2000-04-27 Max Planck Gesellschaft Testkit zur Diagnose von Borreliosen und neue Borrelia-Antigene für die Impfstoffentwicklung
EP1194559B1 (de) 1999-06-18 2006-09-20 Research Foundation Of State University Of New York Gruppen von borrelia burgdorferi, die lyme krankheit verursachen
EP1939294A1 (de) * 2000-08-18 2008-07-02 Research Foundation Of State University Of New York Rekombinante Konstrukte von Borrelia Burgdorferi
EP1865062A3 (de) * 2000-08-18 2008-01-09 Research Foundation Of State University Of New York Verändertes OspA der Borrelia burgdorferi
PT1311540E (pt) * 2000-08-18 2008-03-20 Univ New York State Res Found Ospa de borrelia burgdorferi modificada
WO2008116468A2 (en) 2007-03-26 2008-10-02 Dako Denmark A/S Mhc peptide complexes and uses thereof in infectious diseases
WO2009003493A2 (en) 2007-07-03 2009-01-08 Dako Denmark A/S Mhc multimers, methods for their generation, labeling and use
EP2197908A2 (de) 2007-09-27 2010-06-23 Dako Denmark A/S Mhc-multimere in tuberkulose-diagnostika, -impfstoff und therapeutika
DK2254592T3 (da) 2008-02-28 2019-09-09 Dako Denmark As MHC-multimerer til Borrelia-diagnostik og sygdom
US10722562B2 (en) 2008-07-23 2020-07-28 Immudex Aps Combinatorial analysis and repair
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
US10369204B2 (en) 2008-10-02 2019-08-06 Dako Denmark A/S Molecular vaccines for infectious disease
CN107641151B (zh) * 2010-05-14 2021-10-01 百深公司 Ospa嵌合体及其在疫苗中的用途
RU2015106742A (ru) 2012-07-27 2016-09-20 Бакстер Интернэшнл Инк. Композиции, содержащие химерные молекулы ospa и способы их применения
CZ2014320A3 (cs) * 2014-05-09 2015-11-18 VÝZKUMNÝ ÚSTAV VETERINÁRNÍHO LÉKAŘSTVÍ, v.v.i. Polyepitopový antigen, vakcinační konstrukt a vakcína pro prevenci lymeské boreliózy
WO2016057562A1 (en) * 2014-10-07 2016-04-14 The Research Foundation For The State University Of New York Recombinant borrelia proteins and methods of use thereof
EP3898666A2 (de) 2018-12-17 2021-10-27 Immudex ApS Panel mit borrelia-mhc-multimeren
US12364744B2 (en) * 2020-11-25 2025-07-22 Lankenau Institute For Medical Research Methods and compositions for the diagnosis, prophylaxis and treatment of Lyme disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69122240T2 (de) * 1990-03-05 1997-02-13 The United States of America, represented by the Secretary, U.S. Department of Commerce, Washington, D.C. Antigen-wirkende proteine von borrelia burgdorferi
DK0650527T3 (da) * 1991-10-22 2003-07-14 Symbicom Ab Forbedring af Borrelia burgdorferidiagnose og -profylakse
AU6366894A (en) * 1993-03-11 1994-09-26 Regents Of The University Of California, The Methods, compositions, and kits for diagnosing lyme disease

Also Published As

Publication number Publication date
EP0726955B1 (de) 2004-04-07
DE69433690D1 (de) 2004-05-13
IL111479A0 (en) 1994-12-29
ES2219657T3 (es) 2004-12-01
EP0726955A1 (de) 1996-08-21
DE69433690T2 (de) 2005-03-10
AU8127494A (en) 1995-05-23
DK0726955T3 (da) 2004-08-09
WO1995012676A1 (en) 1995-05-11
CA2175567C (en) 2010-08-10
PT726955E (pt) 2004-08-31
CA2175567A1 (en) 1995-05-11

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