PT1311540E - Ospa de borrelia burgdorferi modificada - Google Patents

Ospa de borrelia burgdorferi modificada Download PDF

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Publication number
PT1311540E
PT1311540E PT01964163T PT01964163T PT1311540E PT 1311540 E PT1311540 E PT 1311540E PT 01964163 T PT01964163 T PT 01964163T PT 01964163 T PT01964163 T PT 01964163T PT 1311540 E PT1311540 E PT 1311540E
Authority
PT
Portugal
Prior art keywords
ospa
alteration
borrelia burgdorferi
ospa polypeptide
altered
Prior art date
Application number
PT01964163T
Other languages
English (en)
Inventor
John J Dunn
Benjamin J Luft
Catherine I Lawson
Shohei Koide
Original Assignee
Univ New York State Res Found
Brookhaven Sciences Ass Llc
Univ Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found, Brookhaven Sciences Ass Llc, Univ Rochester filed Critical Univ New York State Res Found
Publication of PT1311540E publication Critical patent/PT1311540E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Fats And Perfumes (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT01964163T 2000-08-18 2001-08-17 Ospa de borrelia burgdorferi modificada PT1311540E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22648400P 2000-08-18 2000-08-18

Publications (1)

Publication Number Publication Date
PT1311540E true PT1311540E (pt) 2008-03-20

Family

ID=22849087

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01964163T PT1311540E (pt) 2000-08-18 2001-08-17 Ospa de borrelia burgdorferi modificada

Country Status (9)

Country Link
US (3) US20040023325A1 (pt)
EP (1) EP1311540B1 (pt)
AT (1) ATE381575T1 (pt)
AU (1) AU2001285049A1 (pt)
DE (1) DE60131982T2 (pt)
DK (1) DK1311540T3 (pt)
ES (1) ES2298249T3 (pt)
PT (1) PT1311540E (pt)
WO (1) WO2002016421A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7008625B2 (en) * 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
WO2002016421A2 (en) 2000-08-18 2002-02-28 Research Foundation Of The State University Of New York Altered ospa of borrelia burgdorferi
EP2283031B1 (en) * 2008-05-02 2017-04-12 Virginia Commonwealth University Lyme disease vaccine
KR102222869B1 (ko) * 2010-05-14 2021-03-04 박스알타 인코퍼레이티드 키메라 ｏｓｐａ 유전자, 단백질 및 이의 사용 방법
US10100092B2 (en) 2011-11-03 2018-10-16 Vca, Inc. Compositions and methods to detect various infectious organisms
US8986704B2 (en) * 2012-07-06 2015-03-24 Valneva Austria Gmbh Mutant fragments of OspA and methods and uses relating thereto
PL2877206T3 (pl) 2012-07-27 2020-12-14 Baxalta GmbH Kompozycje zawierające chimeryczne cząsteczki ospa i sposoby ich zastosowania
EP3092246B1 (en) * 2014-01-09 2019-06-05 Valneva Austria GmbH Mutant fragments of ospa and methods and uses relating thereto
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
ES2957939T3 (es) 2017-04-13 2024-01-30 Valneva Austria Gmbh Polipéptidos de OspA multivalentes y métodos y usos relacionados con los mismos
EP3773704A1 (en) 2018-04-03 2021-02-17 Sanofi Antigenic respiratory syncytial virus polypeptides
CN112512564A (zh) 2018-04-03 2021-03-16 赛诺菲 铁蛋白蛋白
JP2021519598A (ja) 2018-04-03 2021-08-12 サノフイＳａｎｏｆｉ 抗原性エプスタインバーウイルスポリペプチド
KR20210018205A (ko) * 2018-04-03 2021-02-17 사노피 항원성 OspA 폴리펩타이드
US10749235B2 (en) 2018-09-07 2020-08-18 International Business Machines Corporation Well thermalized microstrip formation for flexible cryogenic microwave lines in quantum applications

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK590288D0 (da) * 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser
US5246844A (en) 1991-10-22 1993-09-21 Board Of Regents, The University Of Texas System Virulence associated proteins in borrelia burgdorferi (bb)
US5777095A (en) * 1988-10-24 1998-07-07 Symbicom Aktiebolag Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90
DE4015911A1 (de) 1989-09-19 1991-03-28 Max Planck Gesellschaft Impfstoff gegen die lyme-krankheit
CA2072008C (en) 1989-12-22 2003-01-28 Renate Fuchs Immunologically active proteins from borrelia burgdorferi, related test kits which contain these proteins and are suitable for detecting antibodies in test fluids, and the use of these proteins as vaccines against infections caused by borrelia strains
US5217872A (en) * 1990-02-27 1993-06-08 The United States Of America As Represented By The Department Of Health And Human Services Method for detection of borrelia burgdorferi antigens
US5470712A (en) * 1990-03-05 1995-11-28 Us Health Antigenic proteins of Borrelia burgdorferi
DE69122240T2 (de) 1990-03-05 1997-02-13 The United States of America, represented by the Secretary, U.S. Department of Commerce, Washington, D.C. Antigen-wirkende proteine von borrelia burgdorferi
JPH06501382A (ja) 1990-06-15 1994-02-17 エール ユニバーシティ ライム病の予防および診断に用いる組成物および方法
EP1016416A3 (en) 1990-07-06 2002-10-23 Wyeth Vaccine against lyme disease and a challenge model for evaluating vaccine efficacy
CA2057536C (en) 1990-12-21 1999-10-26 John J. Dunn Cloning and expression of borrelia lipoproteins
US6221363B1 (en) 1991-07-11 2001-04-24 Baxter Aktiengesellschaft Vaccine for the prevention of lyme disease
ES2135411T3 (es) * 1991-08-15 1999-11-01 Smithkline Beecham Biolog Proteinas osp a de subgrupos de borrelia burgdorferi, genes codificantes y vacunas.
WO1993008299A1 (en) 1991-10-18 1993-04-29 Connaught Laboratories Inc. Preparation of recombinant borrelia proteins
EP0540457A1 (en) 1991-10-22 1993-05-05 Symbicom Ab Improvements in Borrelia burgdorferi diagnosis and prophylaxis
CA2123121A1 (en) 1991-11-12 1993-05-27 Anthony C. Caputa Recombinant vaccine against lyme disease
AU689466B2 (en) 1993-02-26 1998-04-02 Cambridge Biotech Corporation Methods of inducing immunity to lyme disease and a colorimetric assay for borreliacidal activity of antisera
WO1994020536A1 (en) 1993-03-11 1994-09-15 The Regents Of The University Of California Methods, compositions, and kits for diagnosing lyme disease
PL178775B1 (pl) 1993-04-29 2000-06-30 Baxter Ag Kompozycja immunogenna, rekombinacyjne sekwencje DNA, rekombinacyjny wektor ekspresyjny, transformowana komórka gospodarza i antygen OspC
PT726955E (pt) * 1993-11-01 2004-08-31 Brookhaven Science Ass Llc Proteinas quimericas compreendendo polipeptidos borrelia: suas utilizacoes
US6248562B1 (en) * 1993-11-01 2001-06-19 Research Foundation State University Of New York Chimeric proteins comprising borrelia polypeptides and uses therefor
US7008625B2 (en) * 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
US5620862A (en) * 1993-11-24 1997-04-15 University Of Connecticut Methods for diagnosing early Lyme disease
EP1741718A3 (en) 1995-06-07 2007-03-28 Sanofi Pasteur Inc. Expression of lipoproteins
US6251405B1 (en) 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
EP0896583B1 (en) 1996-05-02 2003-02-05 Dako A/S Use of peptide fragments derived from osp-c for diagnostic methods
AUPO069996A0 (en) 1996-06-27 1996-07-18 Australian National University, The Manipulation of plant cellulose
DE19740735A1 (de) 1997-09-16 1999-03-18 Max Planck Gesellschaft Arzneimittel zur Therapie einer manifesten Lyme-Borreliose
DK1100922T3 (da) * 1998-07-31 2008-06-16 Gundersen Lutheran Medical Fou Anvendelser af én eller flere borreliacide epitoper på ydermembranprotein C fra Borrelia burgdorferi (OspC) som vaccine
WO2002016421A2 (en) 2000-08-18 2002-02-28 Research Foundation Of The State University Of New York Altered ospa of borrelia burgdorferi

Also Published As

Publication number Publication date
WO2002016421A9 (en) 2003-09-04
US20090326200A1 (en) 2009-12-31
WO2002016421A8 (en) 2002-07-11
EP1311540B1 (en) 2007-12-19
WO2002016421A3 (en) 2003-03-06
US8992936B2 (en) 2015-03-31
US20040023325A1 (en) 2004-02-05
ATE381575T1 (de) 2008-01-15
AU2001285049A1 (en) 2002-03-04
ES2298249T3 (es) 2008-05-16
US20140030285A1 (en) 2014-01-30
DE60131982D1 (de) 2008-01-31
WO2002016421A2 (en) 2002-02-28
DK1311540T3 (da) 2008-04-28
DE60131982T2 (de) 2008-12-11
US8680236B2 (en) 2014-03-25
EP1311540A2 (en) 2003-05-21

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