JP2013526497A5 - - Google Patents
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- Publication number
- JP2013526497A5 JP2013526497A5 JP2013509505A JP2013509505A JP2013526497A5 JP 2013526497 A5 JP2013526497 A5 JP 2013526497A5 JP 2013509505 A JP2013509505 A JP 2013509505A JP 2013509505 A JP2013509505 A JP 2013509505A JP 2013526497 A5 JP2013526497 A5 JP 2013526497A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- salt
- solvate
- diyl
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 Cc1cc(-c2nc(-c3ccc(*)cc3)n[o]2)n[n]1Cc1cccc(*)c1 Chemical compound Cc1cc(-c2nc(-c3ccc(*)cc3)n[o]2)n[n]1Cc1cccc(*)c1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10004855.2 | 2010-05-08 | ||
| EP10004855 | 2010-05-08 | ||
| PCT/EP2011/057021 WO2011141326A1 (de) | 2010-05-08 | 2011-05-03 | Substituierte heterocyclylbenzyl-pyrazole und ihre verwendung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013526497A JP2013526497A (ja) | 2013-06-24 |
| JP2013526497A5 true JP2013526497A5 (https=) | 2014-06-26 |
| JP5727002B2 JP5727002B2 (ja) | 2015-06-03 |
Family
ID=44063276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509505A Expired - Fee Related JP5727002B2 (ja) | 2010-05-08 | 2011-05-03 | 置換ヘテロサイクリルベンジルピラゾール類およびその使用 |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US20130172311A1 (https=) |
| EP (1) | EP2569312B1 (https=) |
| JP (1) | JP5727002B2 (https=) |
| KR (1) | KR20130108997A (https=) |
| CN (1) | CN103003269B (https=) |
| AR (1) | AR081368A1 (https=) |
| AU (1) | AU2011252223A1 (https=) |
| BR (1) | BR112012028651A2 (https=) |
| CA (1) | CA2798375A1 (https=) |
| CO (1) | CO6640218A2 (https=) |
| CR (1) | CR20120570A (https=) |
| CU (1) | CU20120157A7 (https=) |
| DO (1) | DOP2012000284A (https=) |
| EA (1) | EA201291167A1 (https=) |
| EC (1) | ECSP12012288A (https=) |
| ES (1) | ES2462522T3 (https=) |
| IL (1) | IL222851A0 (https=) |
| MA (1) | MA34939B1 (https=) |
| MX (1) | MX2012012960A (https=) |
| PE (1) | PE20130228A1 (https=) |
| PH (1) | PH12012502202A1 (https=) |
| SG (1) | SG185459A1 (https=) |
| TN (1) | TN2012000531A1 (https=) |
| TW (1) | TW201200510A (https=) |
| UY (1) | UY33369A (https=) |
| WO (1) | WO2011141326A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008247705B2 (en) * | 2007-05-01 | 2012-02-09 | Hill's Pet Nutrition, Inc. | Methods and compositions for diagnosing osteoarthritis in a feline |
| CA2687306A1 (en) * | 2007-05-18 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Heteroaryl substituted pyrazole derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
| CA2798375A1 (en) * | 2010-05-08 | 2011-11-17 | Bayer Intellectual Property Gmbh | Substituted heterocyclyl benzyl pyrazoles, and use thereof |
| EP2867230B1 (en) | 2012-07-02 | 2020-02-12 | Monsanto Technology LLC | Process for the preparation of 3,5-disubstituted-1,2,4-oxadiazoles |
| BR112015003729A2 (pt) | 2012-08-24 | 2018-06-05 | Univ Texas | composto de fórmula estrutural i; composição farmacêutica; método de tratamento de uma doença mediada por caminho do hif; método de tratamento de uma doença causada por proliferação anormal de células; e método para alcançar um efeito em um paciente |
| EP2888253A4 (en) * | 2012-08-24 | 2016-01-06 | Univ Texas | HETEROCYCLIC HIF ACTIVITY MODULATORS FOR THE TREATMENT OF DISEASES |
| WO2014031928A2 (en) * | 2012-08-24 | 2014-02-27 | Philip Jones | Heterocyclic modulators of hif activity for treatment of disease |
| US9663504B2 (en) | 2014-02-25 | 2017-05-30 | Board Of Regents, The University Of Texas System | Salts of heterocyclic modulators of HIF activity for treatment of disease |
| US10191597B2 (en) | 2015-06-30 | 2019-01-29 | Synaptics Incorporated | Modulating a reference voltage to preform capacitive sensing |
| JP7103232B2 (ja) * | 2017-01-13 | 2022-07-20 | 日産化学株式会社 | 芳香族ジアミン化合物前駆体の製造方法 |
| CN115944626B (zh) * | 2022-12-08 | 2024-04-19 | 桂林医学院附属医院 | 小分子化合物在制备抗缺氧或缺血再灌注损伤药物中的应用 |
| WO2025096657A1 (en) * | 2023-10-30 | 2025-05-08 | Pretzel Therapeutics, Inc. | Compositions and inhibitors of polrmt |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610726B2 (en) * | 2001-06-29 | 2003-08-26 | North Shore-Long Island Jewish Research Institute | Compositions and agents for modulating cellular proliferation and angiogenesis |
| CN100387594C (zh) | 2003-04-03 | 2008-05-14 | 麦克公司 | 二芳基取代的吡唑类代谢型谷氨酸受体-5调节剂 |
| JP4499721B2 (ja) | 2003-06-30 | 2010-07-07 | ヒフ バイオ，インク． | 化合物、組成物および方法 |
| CN1842332A (zh) * | 2003-06-30 | 2006-10-04 | Hif生物公司 | 化合物、组合物及方法 |
| GB0508472D0 (en) * | 2005-04-26 | 2005-06-01 | Glaxo Group Ltd | Compounds |
| WO2007065010A2 (en) | 2005-12-02 | 2007-06-07 | Hif Bio, Inc. | Anti-angiogenesis compounds |
| CA2687306A1 (en) * | 2007-05-18 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Heteroaryl substituted pyrazole derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
| PL2356113T3 (pl) * | 2008-11-14 | 2015-06-30 | Bayer Ip Gmbh | Heterocyklicznie podstawione związki arylowe jako inhibitory HIF |
| CN102282142A (zh) * | 2008-11-14 | 2011-12-14 | 拜耳先灵制药股份公司 | 取代的芳族化合物和它们的用途 |
| DE102008057344A1 (de) * | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Aminoalkyl-substituierte Aryl-Verbindungen und ihre Verwendung |
| EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
| ES2405054T3 (es) | 2009-01-23 | 2013-05-30 | Bristol-Myers Squibb Company | Derivados de pirazol-1,2,4-oxadiazol como agonistas de esfingosina-1-fosfato |
| CA2798375A1 (en) * | 2010-05-08 | 2011-11-17 | Bayer Intellectual Property Gmbh | Substituted heterocyclyl benzyl pyrazoles, and use thereof |
-
2011
- 2011-05-03 CA CA2798375A patent/CA2798375A1/en not_active Abandoned
- 2011-05-03 US US13/696,878 patent/US20130172311A1/en not_active Abandoned
- 2011-05-03 AU AU2011252223A patent/AU2011252223A1/en not_active Abandoned
- 2011-05-03 WO PCT/EP2011/057021 patent/WO2011141326A1/de not_active Ceased
- 2011-05-03 BR BR112012028651A patent/BR112012028651A2/pt not_active IP Right Cessation
- 2011-05-03 CN CN201180033637.5A patent/CN103003269B/zh not_active Expired - Fee Related
- 2011-05-03 PH PH1/2012/502202A patent/PH12012502202A1/en unknown
- 2011-05-03 EP EP11716595.1A patent/EP2569312B1/de active Active
- 2011-05-03 ES ES11716595.1T patent/ES2462522T3/es active Active
- 2011-05-03 SG SG2012082145A patent/SG185459A1/en unknown
- 2011-05-03 PE PE2012002121A patent/PE20130228A1/es not_active Application Discontinuation
- 2011-05-03 JP JP2013509505A patent/JP5727002B2/ja not_active Expired - Fee Related
- 2011-05-03 MA MA35350A patent/MA34939B1/fr unknown
- 2011-05-03 KR KR1020127032069A patent/KR20130108997A/ko not_active Withdrawn
- 2011-05-03 MX MX2012012960A patent/MX2012012960A/es active IP Right Grant
- 2011-05-03 EA EA201291167A patent/EA201291167A1/ru unknown
- 2011-05-04 AR ARP110101533A patent/AR081368A1/es not_active Application Discontinuation
- 2011-05-04 UY UY0001033369A patent/UY33369A/es not_active Application Discontinuation
- 2011-05-06 TW TW100115869A patent/TW201200510A/zh unknown
- 2011-05-09 US US13/103,305 patent/US8470811B2/en not_active Expired - Fee Related
-
2012
- 2012-11-05 IL IL222851A patent/IL222851A0/en unknown
- 2012-11-07 CU CU2012000157A patent/CU20120157A7/es unknown
- 2012-11-07 TN TNP2012000531A patent/TN2012000531A1/en unknown
- 2012-11-07 DO DO2012000284A patent/DOP2012000284A/es unknown
- 2012-11-08 EC ECSP12012288 patent/ECSP12012288A/es unknown
- 2012-11-08 CO CO12201711A patent/CO6640218A2/es not_active Application Discontinuation
- 2012-11-08 CR CR20120570A patent/CR20120570A/es unknown
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