JP2013524810A5 - - Google Patents
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- JP2013524810A5 JP2013524810A5 JP2013506194A JP2013506194A JP2013524810A5 JP 2013524810 A5 JP2013524810 A5 JP 2013524810A5 JP 2013506194 A JP2013506194 A JP 2013506194A JP 2013506194 A JP2013506194 A JP 2013506194A JP 2013524810 A5 JP2013524810 A5 JP 2013524810A5
- Authority
- JP
- Japan
- Prior art keywords
- allele
- human
- cvd
- hmg
- coa reductase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32568910P | 2010-04-19 | 2010-04-19 | |
| US61/325,689 | 2010-04-19 | ||
| US33250910P | 2010-05-07 | 2010-05-07 | |
| US61/332,509 | 2010-05-07 | ||
| US40597210P | 2010-10-22 | 2010-10-22 | |
| US61/405,972 | 2010-10-22 | ||
| PCT/US2011/032665 WO2011133418A1 (en) | 2010-04-19 | 2011-04-15 | Genetic polymorphisms associated with statin response and cardiovascular diseases, methods of detection and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015230300A Division JP6157571B2 (ja) | 2010-04-19 | 2015-11-26 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013524810A JP2013524810A (ja) | 2013-06-20 |
| JP2013524810A5 true JP2013524810A5 (https=) | 2014-05-15 |
| JP5918216B2 JP5918216B2 (ja) | 2016-05-18 |
Family
ID=44834462
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013506194A Active JP5918216B2 (ja) | 2010-04-19 | 2011-04-15 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2015230300A Active JP6157571B2 (ja) | 2010-04-19 | 2015-11-26 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2017000353A Withdrawn JP2017063795A (ja) | 2010-04-19 | 2017-01-05 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2018141168A Withdrawn JP2018161156A (ja) | 2010-04-19 | 2018-07-27 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2020031256A Withdrawn JP2020096638A (ja) | 2010-04-19 | 2020-02-27 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2020031255A Active JP6839779B2 (ja) | 2010-04-19 | 2020-02-27 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2021196089A Active JP7175371B2 (ja) | 2010-04-19 | 2021-12-02 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2021196090A Pending JP2022033878A (ja) | 2010-04-19 | 2021-12-02 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
Family Applications After (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015230300A Active JP6157571B2 (ja) | 2010-04-19 | 2015-11-26 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2017000353A Withdrawn JP2017063795A (ja) | 2010-04-19 | 2017-01-05 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2018141168A Withdrawn JP2018161156A (ja) | 2010-04-19 | 2018-07-27 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2020031256A Withdrawn JP2020096638A (ja) | 2010-04-19 | 2020-02-27 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2020031255A Active JP6839779B2 (ja) | 2010-04-19 | 2020-02-27 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2021196089A Active JP7175371B2 (ja) | 2010-04-19 | 2021-12-02 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
| JP2021196090A Pending JP2022033878A (ja) | 2010-04-19 | 2021-12-02 | スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (5) | US20110269735A1 (https=) |
| EP (4) | EP2561352B1 (https=) |
| JP (8) | JP5918216B2 (https=) |
| CA (2) | CA3060628C (https=) |
| WO (1) | WO2011133418A1 (https=) |
Families Citing this family (26)
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| ES2744797T3 (es) * | 2008-02-29 | 2020-02-26 | Univ Oxford Innovation Ltd | Procedimiento de determinación de una dosis adecuada de estatina |
| US9817001B2 (en) | 2008-05-27 | 2017-11-14 | Boston Heart Diagnostics Corporation | Methods for determining LDL cholesterol treatment |
| US8470541B1 (en) | 2008-09-27 | 2013-06-25 | Boston Heart Diagnostics Corporation | Methods for separation and immuno-detection of biomolecules, and apparatus related thereto |
| EP2554679B1 (en) * | 2011-08-05 | 2016-03-02 | Gendiag.exe, S.L. | Genetic markers for cardiovascular disease risk assessment |
| EP2766728B1 (en) * | 2011-10-13 | 2017-09-06 | Boston Heart Diagnostics | Compositions and methods for treating and preventing coronary heart disease |
| US9828624B2 (en) | 2013-07-24 | 2017-11-28 | Boston Heart Diagnostics Corporation | Driving patient compliance with therapy |
| GB201410693D0 (en) | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
| AU2015327836B2 (en) | 2014-10-03 | 2021-07-01 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
| EP3220810A4 (en) | 2014-11-17 | 2018-05-16 | Boston Heart Diagnostic Corporation | Cardiovascular disease risk assessment |
| WO2017044507A2 (en) * | 2015-09-08 | 2017-03-16 | Sirnaomics, Inc. | Sirna/nanoparticle formulations for treatment of middle-east respiratory syndrome coronaviral infection |
| CN108603230A (zh) | 2015-10-09 | 2018-09-28 | 南安普敦大学 | 基因表达的调节与蛋白质表达失调的筛选 |
| CA3001594A1 (en) * | 2015-10-14 | 2017-04-20 | Audentes Therapeutics, Inc. | Nucleic acid molecules containing spacers and methods of use thereof |
| WO2017106377A1 (en) | 2015-12-14 | 2017-06-22 | Cold Spring Harbor Laboratory | Antisense oligomers for treatment of autosomal dominant mental retardation-5 and dravet syndrome |
| US11096956B2 (en) | 2015-12-14 | 2021-08-24 | Stoke Therapeutics, Inc. | Antisense oligomers and uses thereof |
| EP3390666A4 (en) * | 2015-12-14 | 2019-08-07 | Cold Spring Harbor Laboratory | COMPOSITIONS AND METHODS OF TREATING NURSE DISEASES |
| WO2018138709A1 (en) * | 2017-01-30 | 2018-08-02 | National Research Council Of Canada | Blood-brain barrier transmigrating compounds and uses thereof |
| JP2019022483A (ja) * | 2017-07-21 | 2019-02-14 | ポーラ化成工業株式会社 | 肌トラブルリスクの検出方法、その方法に使用するための検出試薬、肌状態鑑別用試薬、及び化粧品又は医薬部外品の選択方法 |
| KR102318434B1 (ko) | 2017-08-25 | 2021-11-01 | 스톡 테라퓨틱스, 인크. | 병태 및 질환 치료용 안티센스 올리고머 |
| CA3099280A1 (en) | 2018-05-04 | 2019-11-07 | Stoke Therapeutics, Inc. | Methods and compositions for treatment of cholesteryl ester storage disease |
| KR102205831B1 (ko) * | 2018-09-21 | 2021-01-21 | 주식회사 녹십자지놈 | 혈중 스타틴 약물농도 예측을 위한 유전자 마커 |
| AU2020227825B2 (en) | 2019-02-27 | 2026-03-26 | Stoke Therapeutics, Inc. | Antisense oligomers for treatment of conditions and diseases |
| EP3935581A4 (en) | 2019-03-04 | 2022-11-30 | Iocurrents, Inc. | DATA COMPRESSION AND COMMUNICATION USING MACHINE LEARNING |
| CN115867657A (zh) | 2020-05-11 | 2023-03-28 | 斯托克制药公司 | 用于治疗疾患和疾病的opa1反义寡聚物 |
| JP2022029001A (ja) * | 2020-07-31 | 2022-02-17 | 株式会社三洋物産 | 遊技機 |
| CN114230626B (zh) * | 2021-11-05 | 2024-09-17 | 康龙化成(宁波)科技发展有限公司 | 一种可在寡聚核酸上一锅法合成四元环内酰胺的方法 |
| WO2024102688A1 (en) * | 2022-11-07 | 2024-05-16 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Compositions for treating osteoclastogenesis disorders and/or rheumatoid arthritis |
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-
2011
- 2011-04-13 US US13/085,955 patent/US20110269735A1/en not_active Abandoned
- 2011-04-15 JP JP2013506194A patent/JP5918216B2/ja active Active
- 2011-04-15 WO PCT/US2011/032665 patent/WO2011133418A1/en not_active Ceased
- 2011-04-15 EP EP11772473.2A patent/EP2561352B1/en active Active
- 2011-04-15 EP EP19207986.1A patent/EP3660508B1/en active Active
- 2011-04-15 CA CA3060628A patent/CA3060628C/en active Active
- 2011-04-15 CA CA2796880A patent/CA2796880C/en active Active
- 2011-04-15 EP EP18163929.5A patent/EP3396376B1/en active Active
- 2011-04-15 EP EP16153844.2A patent/EP3056899B1/en active Active
-
2013
- 2013-03-15 US US13/833,905 patent/US20140235605A1/en not_active Abandoned
-
2015
- 2015-08-25 US US14/834,946 patent/US20160108473A1/en not_active Abandoned
- 2015-11-26 JP JP2015230300A patent/JP6157571B2/ja active Active
-
2017
- 2017-01-05 JP JP2017000353A patent/JP2017063795A/ja not_active Withdrawn
-
2018
- 2018-04-13 US US15/952,792 patent/US10563263B2/en active Active
- 2018-07-27 JP JP2018141168A patent/JP2018161156A/ja not_active Withdrawn
-
2019
- 2019-12-27 US US16/728,333 patent/US11827937B2/en active Active
-
2020
- 2020-02-27 JP JP2020031256A patent/JP2020096638A/ja not_active Withdrawn
- 2020-02-27 JP JP2020031255A patent/JP6839779B2/ja active Active
-
2021
- 2021-12-02 JP JP2021196089A patent/JP7175371B2/ja active Active
- 2021-12-02 JP JP2021196090A patent/JP2022033878A/ja active Pending
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