JP2013542735A5 - - Google Patents

Download PDF

Info

Publication number
JP2013542735A5
JP2013542735A5 JP2013537787A JP2013537787A JP2013542735A5 JP 2013542735 A5 JP2013542735 A5 JP 2013542735A5 JP 2013537787 A JP2013537787 A JP 2013537787A JP 2013537787 A JP2013537787 A JP 2013537787A JP 2013542735 A5 JP2013542735 A5 JP 2013542735A5
Authority
JP
Japan
Prior art keywords
allele
hmg
human
coa reductase
risk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013537787A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013542735A (ja
JP6147192B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/058963 external-priority patent/WO2012061502A2/en
Publication of JP2013542735A publication Critical patent/JP2013542735A/ja
Publication of JP2013542735A5 publication Critical patent/JP2013542735A5/ja
Application granted granted Critical
Publication of JP6147192B2 publication Critical patent/JP6147192B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013537787A 2010-11-02 2011-11-02 静脈血栓症と関連する遺伝子多型およびスタチン応答、その検出方法ならびにその用途 Active JP6147192B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40943410P 2010-11-02 2010-11-02
US61/409,434 2010-11-02
PCT/US2011/058963 WO2012061502A2 (en) 2010-11-02 2011-11-02 Genetic polymorphisms associated with venous thrombosis and statin response, methods of detection and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016014015A Division JP2016063834A (ja) 2010-11-02 2016-01-28 静脈血栓症と関連する遺伝子多型およびスタチン応答、その検出方法ならびにその用途

Publications (3)

Publication Number Publication Date
JP2013542735A JP2013542735A (ja) 2013-11-28
JP2013542735A5 true JP2013542735A5 (https=) 2014-12-18
JP6147192B2 JP6147192B2 (ja) 2017-06-14

Family

ID=45997378

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013537787A Active JP6147192B2 (ja) 2010-11-02 2011-11-02 静脈血栓症と関連する遺伝子多型およびスタチン応答、その検出方法ならびにその用途
JP2016014015A Pending JP2016063834A (ja) 2010-11-02 2016-01-28 静脈血栓症と関連する遺伝子多型およびスタチン応答、その検出方法ならびにその用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016014015A Pending JP2016063834A (ja) 2010-11-02 2016-01-28 静脈血栓症と関連する遺伝子多型およびスタチン応答、その検出方法ならびにその用途

Country Status (5)

Country Link
US (5) US20120108651A1 (https=)
EP (2) EP3495500B1 (https=)
JP (2) JP6147192B2 (https=)
CA (2) CA3159981C (https=)
WO (1) WO2012061502A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009151691A2 (en) * 2008-03-13 2009-12-17 Celera Corporation Genetic polymorphisms associated wiith venous thrombosis, methods of detection and uses thereof
US20120108651A1 (en) 2010-11-02 2012-05-03 Leiden University Medical Center (LUMC) Acting on Behalf of Academic Hospital Leiden (AZL) Genetic polymorphisms associated with venous thrombosis and statin response, methods of detection and uses thereof
RU2556808C2 (ru) * 2013-10-28 2015-07-20 Закрытое акционерное общество "Научно-производственная фирма ДНК-Технология" СПОСОБ ОПРЕДЕЛЕНИЯ ГЕНОТИПА ЧЕЛОВЕКА ПО ПОЛИМОРФНОЙ ПОЗИЦИИ rs1613662 В ГЕНЕ GP6, КОДИРУЮЩЕМ ГЛИКОПРОТЕИН VI
WO2017079551A1 (en) * 2015-11-05 2017-05-11 The Scripps Research Institute Methods for diagnosis and prognosis of venous thrombosis
IT201700086403A1 (it) 2017-07-27 2019-01-27 Univ Del Piemonte Orientale Endothelial-specific promoter sequences and uses thereof
SG11202000840YA (en) 2017-07-31 2020-02-27 Reflection Biotechnologies Ltd Cellular models of and therapies for ocular diseases
CN109517908A (zh) * 2019-01-23 2019-03-26 青岛市中心血站 一种引发溶血性输血反应的ab型变异型的snp位点
EP3935581A4 (en) 2019-03-04 2022-11-30 Iocurrents, Inc. DATA COMPRESSION AND COMMUNICATION USING MACHINE LEARNING
JP2023554540A (ja) * 2020-10-28 2023-12-27 ザ チルドレンズ メディカル センター コーポレーション 切断型修飾組換えａｄａｍｔｓ１３およびその使用
CN114854843A (zh) * 2022-04-29 2022-08-05 青岛市中心血站 一种引发溶血性输血反应的a2血型变异型的snp位点

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US54948A (en) 1866-05-22 Improved boot-jack
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4873191A (en) 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4870009A (en) 1982-11-22 1989-09-26 The Salk Institute For Biological Studies Method of obtaining gene product through the generation of transgenic animals
FR2540122B1 (fr) 1983-01-27 1985-11-29 Centre Nat Rech Scient Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4736866B1 (en) 1984-06-22 1988-04-12 Transgenic non-human mammals
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
NO870613L (no) 1986-03-05 1987-09-07 Molecular Diagnostics Inc Deteksjon av mikroorganismer i en prŸve inneholdende nukleinsyre.
US5004565A (en) 1986-07-17 1991-04-02 The Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5637677A (en) 1987-07-16 1997-06-10 The Trustees Of The University Of Pennsylvania Biologically active compounds and methods of constructing and using the same
US5080891A (en) 1987-08-03 1992-01-14 Ddi Pharmaceuticals, Inc. Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
US5856522A (en) 1995-05-04 1999-01-05 Tropix, Inc. Method of using synthesis of 1,2-dioxetanes and kits therefore
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
JP2897959B2 (ja) 1988-05-20 1999-05-31 エフ．ホフマン―ラ ロシュ アクチェンゲゼルシャフト 固定化された配列特異的プローブ
US4988167A (en) 1988-08-10 1991-01-29 Fergason James L Light blocking and vision restoration apparatus with glint control
US5118801A (en) 1988-09-30 1992-06-02 The Public Health Research Institute Nucleic acid process containing improved molecular switch
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5494810A (en) 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5994073A (en) 1990-08-30 1999-11-30 Tropix, Inc. Enhancement of chemiluminescent assays
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
US5714331A (en) 1991-05-24 1998-02-03 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5270184A (en) 1991-11-19 1993-12-14 Becton, Dickinson And Company Nucleic acid target generation
ATE198358T1 (de) 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
WO1994010300A1 (en) 1992-10-30 1994-05-11 The General Hospital Corporation Interaction trap system for isolating novel proteins
DE69433811T2 (de) 1993-01-07 2005-06-23 Sequenom, Inc., San Diego Dns - sequenzierung durch massenspektronomie
US5422252A (en) 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
WO1995011995A1 (en) 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
US6027923A (en) 1993-07-23 2000-02-22 Bio-Rad Laboratories, Inc. Linked linear amplification of nucleic acids
US5527675A (en) 1993-08-20 1996-06-18 Millipore Corporation Method for degradation and sequencing of polymers which sequentially eliminate terminal residues
US5498531A (en) 1993-09-10 1996-03-12 President And Fellows Of Harvard College Intron-mediated recombinant techniques and reagents
DE4331012A1 (de) 1993-09-13 1995-03-16 Bayer Ag Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
US6015880A (en) 1994-03-16 2000-01-18 California Institute Of Technology Method and substrate for performing multiple sequential reactions on a matrix
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5705333A (en) 1994-08-05 1998-01-06 The Regents Of The University Of California Peptide-based nucleic acid mimics(PENAMS)
US5773628A (en) 1994-11-14 1998-06-30 Tropix, Inc. 1,2-dioxetane compounds with haloalkoxy groups, methods preparation and use
US5591591A (en) 1995-02-09 1997-01-07 Tropix, Inc. Dioxetane compounds for the chemiluminescent detection of proteases, methods of use and kits therefore
US5589136A (en) 1995-06-20 1996-12-31 Regents Of The University Of California Silicon-based sleeve devices for chemical reactions
GB9517780D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
GB9517779D0 (en) 1995-08-31 1995-11-01 Roslin Inst Edinburgh Biological manipulation
US5801115A (en) 1995-09-05 1998-09-01 Kataleuna Gmbh Catalyst composition and methods for using and preparing same
US5679803A (en) 1995-10-25 1997-10-21 Tropix, Inc. 1,2 chemiluminescent dioxetanes of improved performance
EP2332957B1 (en) 1996-02-09 2015-04-08 Cornell Research Foundation, Inc. Detection of nucleic and acid sequence differences using the ligase detection reaction with addressable arrays
US5885470A (en) 1997-04-14 1999-03-23 Caliper Technologies Corporation Controlled fluid transport in microfabricated polymeric substrates
JP2000508912A (ja) 1996-04-19 2000-07-18 スペクトラ バイオメディカル，インコーポレイテッド 多型形態と複数の表現型との相関付け
EP2369007B1 (en) 1996-05-29 2015-07-29 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US5866336A (en) 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6117635A (en) 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US5800999A (en) 1996-12-16 1998-09-01 Tropix, Inc. Dioxetane-precursor-labeled probes and detection assays employing the same
US6234964B1 (en) 1997-03-13 2001-05-22 First Opinion Corporation Disease management system and method
WO1998049548A1 (en) 1997-04-25 1998-11-05 Caliper Technologies Corporation Microfluidic devices incorporating improved channel geometries
US6506594B1 (en) 1999-03-19 2003-01-14 Cornell Res Foundation Inc Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
WO2002072889A2 (en) 2001-01-12 2002-09-19 Applera Corporation Methods and compositions for microarray control
US20030100493A1 (en) * 2001-07-19 2003-05-29 Sol Weiss Sublingual use of inhibitors in the biosynthesis of cholesterol
WO2005056837A2 (en) * 2003-11-26 2005-06-23 Applera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
EP1704253A1 (en) * 2004-01-15 2006-09-27 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Method evolved for recognition of thrombophilia (mert)
CN101193656B (zh) * 2005-06-08 2011-03-02 兴和株式会社 甘油三酸酯降低剂
US7799530B2 (en) * 2005-09-23 2010-09-21 Celera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
US7910303B2 (en) * 2006-10-20 2011-03-22 Celera Corporation Genetic polymorphisms associated with venous thrombosis, methods of detection and uses thereof
US20090221620A1 (en) * 2008-02-20 2009-09-03 Celera Corporation Gentic polymorphisms associated with stroke, methods of detection and uses thereof
WO2009151691A2 (en) * 2008-03-13 2009-12-17 Celera Corporation Genetic polymorphisms associated wiith venous thrombosis, methods of detection and uses thereof
US20120108651A1 (en) 2010-11-02 2012-05-03 Leiden University Medical Center (LUMC) Acting on Behalf of Academic Hospital Leiden (AZL) Genetic polymorphisms associated with venous thrombosis and statin response, methods of detection and uses thereof
EP2811758B1 (en) 2013-06-06 2016-11-02 Harman Becker Automotive Systems GmbH Audio signal mixing

Similar Documents

Publication Publication Date Title
JP2013542735A5 (https=)
JP2013524810A5 (https=)
Wang et al. HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination
JP2011517281A5 (https=)
Vergara et al. Multi-ancestry genome-wide association study of spontaneous clearance of hepatitis C virus
JP2020028293A5 (https=)
US20210164052A1 (en) Methods for predicting response to treatment
JP2014530819A5 (https=)
CA2796561C (en) Genetic factors associated with inhibitor development in hemophilia a
RU2018122965A (ru) Улучшенный способ и набор для определения тяжести и прогрессирования периодонтального заболевания
Gupta et al. Correlation of renin angiotensin system (RAS) candidate gene polymorphisms with response to Ramipril in patients with essential hypertension
JP2019515680A (ja) Ｂ型肝炎ウイルスｃｃｃＤＮＡの定量的測定
Song et al. Association of two variants of the interferon-alpha receptor-1 gene with the presentation of hepatitis B virus infection
JP2016503287A (ja) Ｈｌａ−ｂ＊１３０１対立遺伝子の使用
US12478685B2 (en) Methods and kits for identifying subjects responsive to arginine deprivation therapy
JP2016537030A5 (https=)
JP4228041B2 (ja) 塩基多型の検出方法
JP2013070660A (ja) Ｃ型肝炎患者の経過予測方法
AU2014347768A1 (en) HCV genotyping algorithm
Tah et al. Interleukin-10 Genetic Polymorphisms and Risk of COVID-19 in Yaounde, Cameroon: A Case Control Study
JP7731565B2 (ja) Ｂ型肝炎ワクチンに対する免疫応答性の遺伝的要因を検出する方法及び試薬
WO2011138370A1 (en) Antiviral treatment susceptibility gene and uses thereof
JP7399399B2 (ja) 癌治療後に予後良好群に属するかを判定する方法、及び若年性癌発症リスク群に属するかを判定する方法
Han Development of epigenetic aging clocks by novel targeted sequencing approaches
Khashan et al. Relationship of ACE1 and ACE2 genetic polymorphisms on SARS-CoV-2 infection and severity of symptoms in different regions of Iraq