JP2013520487A - 免疫原性タンパク質および組成物 - Google Patents
免疫原性タンパク質および組成物 Download PDFInfo
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Oncology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
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| GB1003333.0 | 2010-02-26 | ||
| GBGB1003333.0A GB201003333D0 (en) | 2010-02-26 | 2010-02-26 | Immunogenic proteins and compositions |
| PCT/IB2011/000562 WO2011104632A1 (en) | 2010-02-26 | 2011-02-28 | Immunogenic proteins and compositions |
Publications (2)
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| JP2013520487A true JP2013520487A (ja) | 2013-06-06 |
| JP2013520487A5 JP2013520487A5 (enExample) | 2014-02-20 |
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| EP (1) | EP2539360A1 (enExample) |
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| NZ (1) | NZ601488A (enExample) |
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| GB201114923D0 (en) * | 2011-08-30 | 2011-10-12 | Novartis Ag | Immunogenic proteins and compositions |
| EP3169699A4 (en) * | 2014-07-18 | 2018-06-20 | The University of Washington | Cancer vaccine compositions and methods of use thereof |
| US10245310B2 (en) * | 2014-08-05 | 2019-04-02 | Glaxosmithkline Biologicals Sa | Carrier molecule for antigens |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| CN108752480B (zh) * | 2018-05-30 | 2022-03-29 | 中元汇吉生物技术股份有限公司 | 一种免疫原组合物、其制备方法及其用途 |
| CN108840914B (zh) * | 2018-08-13 | 2022-07-01 | 内蒙古民族大学 | 一种具有免疫原性的多肽、其抗体的制备方法以及用途 |
| CN117417419B (zh) * | 2023-01-10 | 2024-04-19 | 康希诺生物股份公司 | 一种百日咳毒素脱毒方法及无细胞百白破联合疫苗 |
Citations (4)
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| JP2008508320A (ja) * | 2004-07-29 | 2008-03-21 | カイロン コーポレイション | Ｓｔｒｅｐｔｏｃｏｃｃｕｓａｇａｌａｃｔｉａｅのようなグラム陽性細菌に対する免疫原性組成物 |
| JP2008532930A (ja) * | 2005-02-01 | 2008-08-21 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | 連鎖球菌性莢膜糖の複合 |
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| WO2009101403A1 (en) * | 2008-02-11 | 2009-08-20 | Novartis Ag | Hybrid polypeptides comprising gbs-80 and spb1 proteins of streptococcus |
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- 2011-02-28 EP EP11717011A patent/EP2539360A1/en not_active Withdrawn
- 2011-02-28 NZ NZ601488A patent/NZ601488A/en not_active IP Right Cessation
- 2011-02-28 US US13/580,724 patent/US20130216568A1/en not_active Abandoned
- 2011-02-28 CN CN2011800113184A patent/CN102770444A/zh active Pending
- 2011-02-28 CA CA2791153A patent/CA2791153A1/en not_active Abandoned
- 2011-02-28 JP JP2012554445A patent/JP2013520487A/ja active Pending
- 2011-02-28 WO PCT/IB2011/000562 patent/WO2011104632A1/en not_active Ceased
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| AU2011219524B2 (en) | 2015-05-21 |
| GB2478203A (en) | 2011-08-31 |
| NZ601488A (en) | 2014-10-31 |
| AU2011219524A1 (en) | 2012-08-23 |
| GB201003333D0 (en) | 2010-04-14 |
| MX2012009758A (es) | 2012-09-12 |
| GB201103423D0 (en) | 2011-04-13 |
| WO2011104632A1 (en) | 2011-09-01 |
| US20130216568A1 (en) | 2013-08-22 |
| EP2539360A1 (en) | 2013-01-02 |
| CA2791153A1 (en) | 2011-09-01 |
| CN102770444A (zh) | 2012-11-07 |
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