CA2791153A1 - Immunogenic proteins and compositions - Google Patents

Immunogenic proteins and compositions Download PDF

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Publication number
CA2791153A1
CA2791153A1 CA2791153A CA2791153A CA2791153A1 CA 2791153 A1 CA2791153 A1 CA 2791153A1 CA 2791153 A CA2791153 A CA 2791153A CA 2791153 A CA2791153 A CA 2791153A CA 2791153 A1 CA2791153 A1 CA 2791153A1
Authority
CA
Canada
Prior art keywords
seq
amino acid
acid sequence
fragment
gbs67
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2791153A
Other languages
English (en)
French (fr)
Inventor
Domenico Maione
Cira Daniela Rinaudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CA2791153A1 publication Critical patent/CA2791153A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2791153A 2010-02-26 2011-02-28 Immunogenic proteins and compositions Abandoned CA2791153A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1003333.0A GB201003333D0 (en) 2010-02-26 2010-02-26 Immunogenic proteins and compositions
GB1003333.0 2010-02-26
PCT/IB2011/000562 WO2011104632A1 (en) 2010-02-26 2011-02-28 Immunogenic proteins and compositions

Publications (1)

Publication Number Publication Date
CA2791153A1 true CA2791153A1 (en) 2011-09-01

Family

ID=42125742

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2791153A Abandoned CA2791153A1 (en) 2010-02-26 2011-02-28 Immunogenic proteins and compositions

Country Status (10)

Country Link
US (1) US20130216568A1 (enExample)
EP (1) EP2539360A1 (enExample)
JP (1) JP2013520487A (enExample)
CN (1) CN102770444A (enExample)
AU (1) AU2011219524B2 (enExample)
CA (1) CA2791153A1 (enExample)
GB (2) GB201003333D0 (enExample)
MX (1) MX2012009758A (enExample)
NZ (1) NZ601488A (enExample)
WO (1) WO2011104632A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201114923D0 (en) * 2011-08-30 2011-10-12 Novartis Ag Immunogenic proteins and compositions
EP3169699A4 (en) * 2014-07-18 2018-06-20 The University of Washington Cancer vaccine compositions and methods of use thereof
BR112017002183A2 (pt) * 2014-08-05 2018-01-16 Glaxosmithkline Biologicals S.A. conjugado, composição farmacêutica, e, método para aumentar uma resposta imune em um mamífero
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN108752480B (zh) * 2018-05-30 2022-03-29 中元汇吉生物技术股份有限公司 一种免疫原组合物、其制备方法及其用途
CN108840914B (zh) * 2018-08-13 2022-07-01 内蒙古民族大学 一种具有免疫原性的多肽、其抗体的制备方法以及用途
CN117417419B (zh) * 2023-01-10 2024-04-19 康希诺生物股份公司 一种百日咳毒素脱毒方法及无细胞百白破联合疫苗

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Also Published As

Publication number Publication date
EP2539360A1 (en) 2013-01-02
US20130216568A1 (en) 2013-08-22
NZ601488A (en) 2014-10-31
GB201103423D0 (en) 2011-04-13
JP2013520487A (ja) 2013-06-06
MX2012009758A (es) 2012-09-12
GB201003333D0 (en) 2010-04-14
WO2011104632A1 (en) 2011-09-01
CN102770444A (zh) 2012-11-07
AU2011219524A1 (en) 2012-08-23
AU2011219524B2 (en) 2015-05-21
GB2478203A (en) 2011-08-31

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Effective date: 20170228