JP2013518110A - 疼痛および他の適応症の治療用の医薬組成物 - Google Patents

疼痛および他の適応症の治療用の医薬組成物 Download PDF

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JP2013518110A
JP2013518110A JP2012551232A JP2012551232A JP2013518110A JP 2013518110 A JP2013518110 A JP 2013518110A JP 2012551232 A JP2012551232 A JP 2012551232A JP 2012551232 A JP2012551232 A JP 2012551232A JP 2013518110 A JP2013518110 A JP 2013518110A
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JP2013518110A5 (enExample
Inventor
チヨバニアン，ハリー
リン，ライナス・エス
リユウ，ピン
チオダ，マーク・デイー
デビタ，ロバート・ジエイ
ナーガンド，ラバイ・ピー
グオ，ヤン
ハミル，テレンス
リー，ウエンピン
ヘンゼ，ダレル・エー
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Merck and Co Inc
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Merck and Co Inc
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Publication of JP2013518110A publication Critical patent/JP2013518110A/ja
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    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4164—1,3-Diazoles
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  • Neurology (AREA)
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  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
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JP2012551232A 2010-01-28 2011-01-25 疼痛および他の適応症の治療用の医薬組成物 Withdrawn JP2013518110A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29908710P 2010-01-28 2010-01-28
US61/299,087 2010-01-28
PCT/US2011/022412 WO2011094209A1 (en) 2010-01-28 2011-01-25 Pharmaceutical compositions for the treatment of pain and other indicatons

Publications (2)

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JP2013518110A true JP2013518110A (ja) 2013-05-20
JP2013518110A5 JP2013518110A5 (enExample) 2014-03-13

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JP2012551232A Withdrawn JP2013518110A (ja) 2010-01-28 2011-01-25 疼痛および他の適応症の治療用の医薬組成物

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US (1) US20130030000A1 (enExample)
EP (1) EP2528603A4 (enExample)
JP (1) JP2013518110A (enExample)
KR (1) KR20120123691A (enExample)
CN (1) CN102858338A (enExample)
AU (1) AU2011209754A1 (enExample)
BR (1) BR112012018913A2 (enExample)
CA (1) CA2786888A1 (enExample)
MX (1) MX2012008801A (enExample)
RU (1) RU2012136624A (enExample)
WO (1) WO2011094209A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013523814A (ja) * 2010-04-08 2013-06-17 メルク・シャープ・エンド・ドーム・コーポレイション Ｆａａｈの調節薬として有用なオキサゾール誘導体
JP7464955B2 (ja) 2020-02-27 2024-04-10 国立大学法人千葉大学 ヨードオキサゾール化合物の製造方法、オキサゾール化合物の製造方法

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2732526A1 (en) * 2008-08-04 2010-02-11 Merck Sharp & Dohme Corp. Oxazole derivatives useful as inhibitors of faah
WO2011133444A1 (en) 2010-04-21 2011-10-27 Merck Sharp & Dohme Corp. Substituted pyrimidines
EP2582373A4 (en) 2010-06-16 2013-10-30 Bruce Chandler May USE OF LEVOCETIRIZIN AND MONTELUKAST IN THE TREATMENT OF INFLUENZA, COLLECTIONS AND INFLAMMATION
JO3407B1 (ar) 2012-05-31 2019-10-20 Eisai R&D Man Co Ltd مركبات رباعي هيدرو بيرازولو بيريميدين
WO2014164285A2 (en) 2013-03-13 2014-10-09 Inflammatory Response Research, Inc. Use of levocetirizine and montelukast in the treatment of vasculitis
ES2660494T3 (es) 2013-03-13 2018-03-22 14779507 Uso de levocetirizina y montelukast en el tratamiento de una lesión traumática
CA2901421A1 (en) 2013-03-13 2014-10-09 Bruce Chandler May Use of levocetirizine and montelukast in the treatment of autoimmune disorders
JP6483666B2 (ja) 2013-10-14 2019-03-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 選択的に置換されたキノリン化合物
WO2015057659A1 (en) 2013-10-14 2015-04-23 Eisai R&D Management Co., Ltd. Selectively substituted quinoline compounds
PL3077047T3 (pl) * 2013-12-04 2019-10-31 Galmed Res & Development Ltd Sole aramcholu
WO2016036588A1 (en) * 2014-09-03 2016-03-10 Merck Sharp & Dohme Corp. Pharmaceutical suspensions containing etoricoxib
EP3193875B1 (en) 2014-09-15 2022-02-16 Inflammatory Response Research, Inc. Levocetirizine and montelukast in the treatment of inflammation mediated conditions
PL3595665T3 (pl) * 2017-03-13 2025-01-13 Lundbeck La Jolla Research Center, Inc. Podwójne inhibitory magl i faah
WO2019008115A1 (en) 2017-07-07 2019-01-10 Syngenta Participations Ag HETEROCYCLIC DERIVATIVES HAVING PESTICIDE ACTIVITY HAVING SUBSTITUENTS CONTAINING SULFUR
KR102257685B1 (ko) 2018-09-20 2021-05-31 성균관대학교산학협력단 Cox-2 억제제를 유효성분으로 포함하는 소염진통 예방 또는 치료용 정제 조성물
CN110156710B (zh) * 2019-04-30 2022-10-28 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 一种多取代噁唑类化合物的制备方法
WO2021236518A1 (en) * 2020-05-19 2021-11-25 IRR, Inc. Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof
WO2022251707A1 (en) * 2021-05-28 2022-12-01 Ananda Scientific, Inc. Methods for the treatment of post-traumatic stress disorder and traumatic brain injury with cannabinoids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA008767B1 (ru) * 2002-10-08 2007-08-31 Зе Скрипс Ресеч Инститьют Ингибиторы гидролазы амидов жирных кислот
HRP20150765T1 (hr) * 2004-12-30 2015-10-09 Janssen Pharmaceutica N.V. Amid derivati piperidin- i piperazin-1-karboksilne kiseline te povezani spojevi kao modulatori amid hidrolaze masnih kiselina (faah) za lijeäśenje tjeskobe, boli i drugih stanja
EP1866293A1 (en) * 2005-03-31 2007-12-19 UCB Pharma, S.A. Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
AU2008257154B2 (en) * 2007-05-25 2014-03-06 The Scripps Research Institute Tetracyclic inhibitors of fatty acid amide hydrolase
JP2011523959A (ja) * 2008-06-11 2011-08-25 メルク・シャープ・エンド・ドーム・コーポレイション Ｆａａｈの阻害剤として有用なイミダゾール誘導体
JP2011524872A (ja) * 2008-06-11 2011-09-08 メルク・シャープ・エンド・ドーム・コーポレイション Ｆａａｈの阻害剤として有用なピラゾール誘導体
CA2732526A1 (en) * 2008-08-04 2010-02-11 Merck Sharp & Dohme Corp. Oxazole derivatives useful as inhibitors of faah

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013523814A (ja) * 2010-04-08 2013-06-17 メルク・シャープ・エンド・ドーム・コーポレイション Ｆａａｈの調節薬として有用なオキサゾール誘導体
JP7464955B2 (ja) 2020-02-27 2024-04-10 国立大学法人千葉大学 ヨードオキサゾール化合物の製造方法、オキサゾール化合物の製造方法

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CN102858338A (zh) 2013-01-02
MX2012008801A (es) 2012-08-17
EP2528603A4 (en) 2013-09-04
EP2528603A1 (en) 2012-12-05
RU2012136624A (ru) 2014-03-10
BR112012018913A2 (pt) 2017-06-20
US20130030000A1 (en) 2013-01-31
AU2011209754A1 (en) 2012-07-26
CA2786888A1 (en) 2011-08-04
WO2011094209A1 (en) 2011-08-04
KR20120123691A (ko) 2012-11-09

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