CN102858338A - 治疗疼痛及其它适应症的药物组合物 - Google Patents

治疗疼痛及其它适应症的药物组合物 Download PDF

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Publication number
CN102858338A
CN102858338A CN2011800171616A CN201180017161A CN102858338A CN 102858338 A CN102858338 A CN 102858338A CN 2011800171616 A CN2011800171616 A CN 2011800171616A CN 201180017161 A CN201180017161 A CN 201180017161A CN 102858338 A CN102858338 A CN 102858338A
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alkyl
halo
optionally substituted
pain
mono
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Chinese (zh)
Inventor
H.乔巴尼安
L.S.林
刘平
M.D.基奥达
R.J.德维塔
R.P.纳冈
郭燕
T.哈米尔
李文萍
D.A.亨策
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Merck Sharp and Dohme LLC
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Merck Sharp and Dohme LLC
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4164—1,3-Diazoles
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  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
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  • Rheumatology (AREA)
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  • Hematology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
CN2011800171616A 2010-01-28 2011-01-25 治疗疼痛及其它适应症的药物组合物 Pending CN102858338A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29908710P 2010-01-28 2010-01-28
US61/299,087 2010-01-28
PCT/US2011/022412 WO2011094209A1 (en) 2010-01-28 2011-01-25 Pharmaceutical compositions for the treatment of pain and other indicatons

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CN102858338A true CN102858338A (zh) 2013-01-02

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US (1) US20130030000A1 (enExample)
EP (1) EP2528603A4 (enExample)
JP (1) JP2013518110A (enExample)
KR (1) KR20120123691A (enExample)
CN (1) CN102858338A (enExample)
AU (1) AU2011209754A1 (enExample)
BR (1) BR112012018913A2 (enExample)
CA (1) CA2786888A1 (enExample)
MX (1) MX2012008801A (enExample)
RU (1) RU2012136624A (enExample)
WO (1) WO2011094209A1 (enExample)

Cited By (1)

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CN110709084A (zh) * 2017-03-13 2020-01-17 阿比德治疗公司 双重magl和faah抑制剂

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CA2732526A1 (en) * 2008-08-04 2010-02-11 Merck Sharp & Dohme Corp. Oxazole derivatives useful as inhibitors of faah
AU2011238487B2 (en) * 2010-04-08 2015-10-01 Merck Sharp & Dohme Corp. Oxazole derivatives useful as modulators of FAAH
WO2011133444A1 (en) 2010-04-21 2011-10-27 Merck Sharp & Dohme Corp. Substituted pyrimidines
EP2582373A4 (en) 2010-06-16 2013-10-30 Bruce Chandler May USE OF LEVOCETIRIZIN AND MONTELUKAST IN THE TREATMENT OF INFLUENZA, COLLECTIONS AND INFLAMMATION
JO3407B1 (ar) 2012-05-31 2019-10-20 Eisai R&D Man Co Ltd مركبات رباعي هيدرو بيرازولو بيريميدين
WO2014164285A2 (en) 2013-03-13 2014-10-09 Inflammatory Response Research, Inc. Use of levocetirizine and montelukast in the treatment of vasculitis
ES2660494T3 (es) 2013-03-13 2018-03-22 14779507 Uso de levocetirizina y montelukast en el tratamiento de una lesión traumática
CA2901421A1 (en) 2013-03-13 2014-10-09 Bruce Chandler May Use of levocetirizine and montelukast in the treatment of autoimmune disorders
JP6483666B2 (ja) 2013-10-14 2019-03-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 選択的に置換されたキノリン化合物
WO2015057659A1 (en) 2013-10-14 2015-04-23 Eisai R&D Management Co., Ltd. Selectively substituted quinoline compounds
PL3077047T3 (pl) * 2013-12-04 2019-10-31 Galmed Res & Development Ltd Sole aramcholu
WO2016036588A1 (en) * 2014-09-03 2016-03-10 Merck Sharp & Dohme Corp. Pharmaceutical suspensions containing etoricoxib
EP3193875B1 (en) 2014-09-15 2022-02-16 Inflammatory Response Research, Inc. Levocetirizine and montelukast in the treatment of inflammation mediated conditions
WO2019008115A1 (en) 2017-07-07 2019-01-10 Syngenta Participations Ag HETEROCYCLIC DERIVATIVES HAVING PESTICIDE ACTIVITY HAVING SUBSTITUENTS CONTAINING SULFUR
KR102257685B1 (ko) 2018-09-20 2021-05-31 성균관대학교산학협력단 Cox-2 억제제를 유효성분으로 포함하는 소염진통 예방 또는 치료용 정제 조성물
CN110156710B (zh) * 2019-04-30 2022-10-28 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 一种多取代噁唑类化合物的制备方法
JP7464955B2 (ja) 2020-02-27 2024-04-10 国立大学法人千葉大学 ヨードオキサゾール化合物の製造方法、オキサゾール化合物の製造方法
WO2021236518A1 (en) * 2020-05-19 2021-11-25 IRR, Inc. Levocetirizine and montelukast in the treatment of sepsis and symptoms thereof
WO2022251707A1 (en) * 2021-05-28 2022-12-01 Ananda Scientific, Inc. Methods for the treatment of post-traumatic stress disorder and traumatic brain injury with cannabinoids

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CN101146786A (zh) * 2004-12-30 2008-03-19 詹森药业有限公司 作为脂肪酸酰胺水解酶调节剂的哌嗪基脲和哌啶基脲
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WO2009152025A1 (en) * 2008-06-11 2009-12-17 Merck & Co., Inc. Imidazole derivatives useful as inhibitors of faah
CN102171196A (zh) * 2008-08-04 2011-08-31 默沙东公司 用作脂肪酸酰胺水解酶的抑制剂的*唑衍生物

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S. G. PIL’O ET AL.: "Synthesis of New 5-Mercapto-1,3-oxazole Derivatives on the Basis of 2-Acylamino-3,3-dichloroacrylonitriles and Their Analogs", 《RUSSIAN JOURNAL OF GENERAL CHEMISTRY》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110709084A (zh) * 2017-03-13 2020-01-17 阿比德治疗公司 双重magl和faah抑制剂

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MX2012008801A (es) 2012-08-17
EP2528603A4 (en) 2013-09-04
EP2528603A1 (en) 2012-12-05
RU2012136624A (ru) 2014-03-10
BR112012018913A2 (pt) 2017-06-20
US20130030000A1 (en) 2013-01-31
AU2011209754A1 (en) 2012-07-26
CA2786888A1 (en) 2011-08-04
WO2011094209A1 (en) 2011-08-04
JP2013518110A (ja) 2013-05-20
KR20120123691A (ko) 2012-11-09

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Application publication date: 20130102