JP2013507991A5 - - Google Patents
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- JP2013507991A5 JP2013507991A5 JP2012536968A JP2012536968A JP2013507991A5 JP 2013507991 A5 JP2013507991 A5 JP 2013507991A5 JP 2012536968 A JP2012536968 A JP 2012536968A JP 2012536968 A JP2012536968 A JP 2012536968A JP 2013507991 A5 JP2013507991 A5 JP 2013507991A5
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- 102000025171 antigen binding proteins Human genes 0.000 claims 38
- 108091000831 antigen binding proteins Proteins 0.000 claims 38
- 125000000539 amino acid group Chemical group 0.000 claims 27
- 125000003275 alpha amino acid group Chemical group 0.000 claims 26
- 238000006467 substitution reaction Methods 0.000 claims 20
- 238000012217 deletion Methods 0.000 claims 19
- 230000037430 deletion Effects 0.000 claims 19
- 238000003780 insertion Methods 0.000 claims 18
- 230000037431 insertion Effects 0.000 claims 18
- 108010065637 Interleukin-23 Proteins 0.000 claims 15
- 102000013264 Interleukin-23 Human genes 0.000 claims 15
- 239000002904 solvent Substances 0.000 claims 6
- 101000852980 Homo sapiens Interleukin-23 subunit alpha Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 claims 2
- 238000007792 addition Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000000770 proinflammatory effect Effects 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
- 238000002424 x-ray crystallography Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25498209P | 2009-10-26 | 2009-10-26 | |
| US61/254,982 | 2009-10-26 | ||
| US38128710P | 2010-09-09 | 2010-09-09 | |
| US61/381,287 | 2010-09-09 | ||
| PCT/US2010/054148 WO2011056600A1 (en) | 2009-10-26 | 2010-10-26 | Human il-23 antigen binding proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015236268A Division JP2016102122A (ja) | 2009-10-26 | 2015-12-03 | ヒトｉｌ−２３抗原結合タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013507991A JP2013507991A (ja) | 2013-03-07 |
| JP2013507991A5 true JP2013507991A5 (enExample) | 2013-12-05 |
| JP5930968B2 JP5930968B2 (ja) | 2016-06-08 |
Family
ID=43413789
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012536968A Active JP5930968B2 (ja) | 2009-10-26 | 2010-10-26 | ヒトｉｌ−２３抗原結合タンパク質 |
| JP2015236268A Pending JP2016102122A (ja) | 2009-10-26 | 2015-12-03 | ヒトｉｌ−２３抗原結合タンパク質 |
| JP2018045121A Pending JP2018117626A (ja) | 2009-10-26 | 2018-03-13 | ヒトｉｌ−２３抗原結合タンパク質 |
| JP2019166277A Active JP7023908B2 (ja) | 2009-10-26 | 2019-09-12 | ヒトｉｌ－２３抗原結合タンパク質 |
| JP2021177428A Active JP7278355B2 (ja) | 2009-10-26 | 2021-10-29 | ヒトｉｌ－２３抗原結合タンパク質 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015236268A Pending JP2016102122A (ja) | 2009-10-26 | 2015-12-03 | ヒトｉｌ−２３抗原結合タンパク質 |
| JP2018045121A Pending JP2018117626A (ja) | 2009-10-26 | 2018-03-13 | ヒトｉｌ−２３抗原結合タンパク質 |
| JP2019166277A Active JP7023908B2 (ja) | 2009-10-26 | 2019-09-12 | ヒトｉｌ－２３抗原結合タンパク質 |
| JP2021177428A Active JP7278355B2 (ja) | 2009-10-26 | 2021-10-29 | ヒトｉｌ－２３抗原結合タンパク質 |
Country Status (39)
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| CN111718414B (zh) * | 2020-06-12 | 2021-03-02 | 江苏荃信生物医药有限公司 | 抗人白介素23单克隆抗体及其应用 |
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| CN112625129B (zh) * | 2020-11-26 | 2022-05-20 | 江苏荃信生物医药股份有限公司 | 一种抗人白介素23及包含其的试剂盒及其检测方法 |
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| US8927693B2 (en) | 2010-02-18 | 2015-01-06 | Bristol-Myers Squibb Company | Fibronectin based scaffold domain proteins that bind IL-23 |
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