JP2018064580A5 - - Google Patents
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- JP2018064580A5 JP2018064580A5 JP2017239124A JP2017239124A JP2018064580A5 JP 2018064580 A5 JP2018064580 A5 JP 2018064580A5 JP 2017239124 A JP2017239124 A JP 2017239124A JP 2017239124 A JP2017239124 A JP 2017239124A JP 2018064580 A5 JP2018064580 A5 JP 2018064580A5
- Authority
- JP
- Japan
- Prior art keywords
- subtype
- seq
- amino acid
- acid sequence
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 241000712461 unidentified influenza virus Species 0.000 claims 55
- 125000003275 alpha amino acid group Chemical group 0.000 claims 54
- 101710154606 Hemagglutinin Proteins 0.000 claims 48
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 48
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 48
- 101710176177 Protein A56 Proteins 0.000 claims 48
- 239000000185 hemagglutinin Substances 0.000 claims 47
- 229920001184 polypeptide Polymers 0.000 claims 44
- 102000004196 processed proteins & peptides Human genes 0.000 claims 44
- 108090000765 processed proteins & peptides Proteins 0.000 claims 43
- 239000000203 mixture Substances 0.000 claims 26
- 239000012634 fragment Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 11
- 108020004707 nucleic acids Proteins 0.000 claims 11
- 102000039446 nucleic acids Human genes 0.000 claims 11
- 150000007523 nucleic acids Chemical class 0.000 claims 11
- 230000002238 attenuated effect Effects 0.000 claims 10
- 230000002163 immunogen Effects 0.000 claims 10
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 6
- 241000712431 Influenza A virus Species 0.000 claims 5
- 238000001415 gene therapy Methods 0.000 claims 4
- 210000004408 hybridoma Anatomy 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 3
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 230000036039 immunity Effects 0.000 claims 2
- 206010022000 influenza Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 241000700199 Cavia porcellus Species 0.000 claims 1
- 241000282693 Cercopithecidae Species 0.000 claims 1
- 241000699666 Mus <mouse, genus> Species 0.000 claims 1
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 1
- 241000282577 Pan troglodytes Species 0.000 claims 1
- 241000845082 Panama Species 0.000 claims 1
- 241000700159 Rattus Species 0.000 claims 1
- 208000037797 influenza A Diseases 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18126309P | 2009-05-26 | 2009-05-26 | |
| US61/181,263 | 2009-05-26 | ||
| US22430209P | 2009-07-09 | 2009-07-09 | |
| US61/224,302 | 2009-07-09 | ||
| US30589810P | 2010-02-18 | 2010-02-18 | |
| US61/305,898 | 2010-02-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016014445A Division JP2016127846A (ja) | 2009-05-26 | 2016-01-28 | 周期的投与によって作製されたインフルエンザウイルスに対するモノクローナル抗体及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018064580A JP2018064580A (ja) | 2018-04-26 |
| JP2018064580A5 true JP2018064580A5 (enExample) | 2018-08-30 |
Family
ID=42352512
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012513195A Expired - Fee Related JP5941841B2 (ja) | 2009-05-26 | 2010-05-26 | 周期的投与によって作製されたインフルエンザウイルスに対するモノクローナル抗体及びその使用 |
| JP2016014445A Pending JP2016127846A (ja) | 2009-05-26 | 2016-01-28 | 周期的投与によって作製されたインフルエンザウイルスに対するモノクローナル抗体及びその使用 |
| JP2017239124A Pending JP2018064580A (ja) | 2009-05-26 | 2017-12-14 | 周期的投与によって作製されたインフルエンザウイルスに対するモノクローナル抗体及びその使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012513195A Expired - Fee Related JP5941841B2 (ja) | 2009-05-26 | 2010-05-26 | 周期的投与によって作製されたインフルエンザウイルスに対するモノクローナル抗体及びその使用 |
| JP2016014445A Pending JP2016127846A (ja) | 2009-05-26 | 2016-01-28 | 周期的投与によって作製されたインフルエンザウイルスに対するモノクローナル抗体及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8673314B2 (enExample) |
| EP (1) | EP2435475B1 (enExample) |
| JP (3) | JP5941841B2 (enExample) |
| AU (1) | AU2010254136B2 (enExample) |
| CA (1) | CA2800182A1 (enExample) |
| WO (1) | WO2010138564A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011063127A1 (en) | 2009-11-18 | 2011-05-26 | University Of Medicine And Dentistry Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| US9051359B2 (en) | 2009-03-30 | 2015-06-09 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
| JP5941841B2 (ja) | 2009-05-26 | 2016-06-29 | アイカーン スクール オブ メディシン アット マウント サイナイ | 周期的投与によって作製されたインフルエンザウイルスに対するモノクローナル抗体及びその使用 |
| US9849192B2 (en) | 2009-11-18 | 2017-12-26 | Rutgers, The State University Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| JP2013520172A (ja) * | 2010-02-18 | 2013-06-06 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルス疾患の予防及び治療で用いるためのワクチン |
| JP2013526849A (ja) | 2010-03-30 | 2013-06-27 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルスワクチン及びその使用 |
| BR112013025254A2 (pt) * | 2011-04-21 | 2016-09-06 | Baxter Internat Inc E Baxter Healthcare S A | método para isolar um antígeno de uma composição de vacina |
| AR087364A1 (es) * | 2011-07-29 | 2014-03-19 | Pf Medicament | Anticuerpo anti-cxcr4 y su uso para la deteccion y dianostico de canceres |
| KR102101478B1 (ko) * | 2011-08-10 | 2020-04-16 | 란케나우 인스티튜트 포 메디칼 리서치 | 자가면역 및 염증성 질환의 치료를 위한 방법 및 조성물 |
| GB201115214D0 (en) * | 2011-09-02 | 2011-10-19 | Health Prot Agency | Influenza virus antibody compositions |
| EP4241785A3 (en) | 2011-09-20 | 2023-09-27 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
| EP2785737A2 (en) | 2011-12-02 | 2014-10-08 | AIMM Therapeutics B.V. | Influenza a virus specific antibodies |
| MY170407A (en) * | 2012-03-08 | 2019-07-27 | Crucell Holland Bv | Human binding molecules capable of binding to and neutralizing influenza b viruses and uses thereof |
| CN102621320B (zh) * | 2012-03-20 | 2014-07-02 | 中国检验检疫科学研究院 | 一种用于快速检测人禽流感病毒的非诊断性双抗体夹心法 |
| WO2014055663A1 (en) | 2012-10-02 | 2014-04-10 | Rutgers, The State University Of New Jersey | Specific delivery of toxins conjugated wtih antibodies to activated matriptase |
| WO2014099931A1 (en) | 2012-12-18 | 2014-06-26 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
| IL241552B2 (en) | 2013-03-14 | 2023-09-01 | Contrafect Corp | Preparation and methods based on neutralizing antibodies administered intranasally for increased therapeutic efficacy |
| WO2014159960A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
| WO2014143886A2 (en) * | 2013-03-15 | 2014-09-18 | Edimer Pharmaceuticals, Inc. | Anti-ectodysplasin antibodies |
| US20160200799A1 (en) * | 2013-08-23 | 2016-07-14 | Fujita Health University | Anti-influenza virus neutralizing antibody |
| EP3733244A1 (en) * | 2013-10-02 | 2020-11-04 | Medlmmune, LLC | Neutralizing anti-influenza a antibodies and uses thereof |
| CA2938726A1 (en) | 2014-02-04 | 2015-08-13 | Contrafect Corporation | Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof |
| US10639370B2 (en) | 2014-02-04 | 2020-05-05 | Contrafect Corporation | Antibodies useful in passive influenza immunization, and compositions, combinations and methods for use thereof |
| TWI702229B (zh) | 2014-12-19 | 2020-08-21 | 美商再生元醫藥公司 | 流行性感冒病毒血球凝集素之人類抗體 |
| US10736956B2 (en) | 2015-01-23 | 2020-08-11 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccination regimens |
| CN107530427A (zh) | 2015-03-27 | 2018-01-02 | 南加利福尼亚大学 | 针对用于实体肿瘤的治疗的lhr的car t细胞疗法 |
| US20180118831A1 (en) * | 2015-03-27 | 2018-05-03 | University Of Southern California | Car t-cells for the treatment of b7-h4 expressing solid tumors |
| JP7145374B2 (ja) | 2016-03-18 | 2022-10-03 | ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー | インビボでの切断可能連結部分によって抗マトリプターゼ抗体にコンジュゲートされた化学療法剤を用いる腫瘍細胞の標的化 |
| US11185582B2 (en) | 2016-05-09 | 2021-11-30 | Icahn School Of Medicine At Mount Sinai | Broadly neutralizing anti-human cytomegalovirus (HCMV) antibodies and methods of use thereof |
| EP3471767A4 (en) | 2016-06-15 | 2020-01-15 | Icahn School of Medicine at Mount Sinai | Influenza virus hemagglutinin proteins and uses thereof |
| WO2018187706A2 (en) | 2017-04-07 | 2018-10-11 | Icahn School Of Medicine At Mount Sinai | Anti-influenza b virus neuraminidase antibodies and uses thereof |
| EP3672636A4 (en) * | 2017-08-23 | 2021-05-12 | Brown University | PROCEDURES AND COMPOSITIONS RELATED TO ANTI-CHI3L1 ANTIBODY REAGENTS |
| US10766968B2 (en) | 2017-08-23 | 2020-09-08 | Brown University | Methods and compositions relating to anti-CHI3L1 antibody reagents to treat cancer |
| US12364746B2 (en) | 2018-06-21 | 2025-07-22 | Icahn School Of Medicine At Mount Sinai | Mosaic influenza virus hemagglutinin polypeptides and uses thereof |
| WO2023240272A2 (en) * | 2022-06-09 | 2023-12-14 | Santa Ana Bio, Inc. | Antibodies targeting c-kit and/or siglec and uses thereof |
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| JP5941841B2 (ja) | 2009-05-26 | 2016-06-29 | アイカーン スクール オブ メディシン アット マウント サイナイ | 周期的投与によって作製されたインフルエンザウイルスに対するモノクローナル抗体及びその使用 |
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| WO2011014645A1 (en) | 2009-07-30 | 2011-02-03 | Mount Sinai School Of Medicine Of New York University | Influenza viruses and uses thereof |
| JP2013520172A (ja) | 2010-02-18 | 2013-06-06 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルス疾患の予防及び治療で用いるためのワクチン |
| JP2013526849A (ja) | 2010-03-30 | 2013-06-27 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルスワクチン及びその使用 |
| ES2739711T3 (es) | 2010-07-22 | 2020-02-03 | John W Schrader | Anticuerpo de protección cruzada contra la infección por el virus de la gripe |
| EP4241785A3 (en) | 2011-09-20 | 2023-09-27 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
| WO2014099931A1 (en) | 2012-12-18 | 2014-06-26 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
-
2010
- 2010-05-26 JP JP2012513195A patent/JP5941841B2/ja not_active Expired - Fee Related
- 2010-05-26 CA CA2800182A patent/CA2800182A1/en not_active Abandoned
- 2010-05-26 US US12/788,103 patent/US8673314B2/en active Active
- 2010-05-26 WO PCT/US2010/036170 patent/WO2010138564A1/en not_active Ceased
- 2010-05-26 AU AU2010254136A patent/AU2010254136B2/en not_active Ceased
- 2010-05-26 EP EP10720978.5A patent/EP2435475B1/en active Active
-
2014
- 2014-01-23 US US14/162,354 patent/US9175069B2/en active Active
-
2015
- 2015-04-29 US US14/699,273 patent/US20150239960A1/en not_active Abandoned
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2016
- 2016-01-28 JP JP2016014445A patent/JP2016127846A/ja active Pending
-
2017
- 2017-12-14 JP JP2017239124A patent/JP2018064580A/ja active Pending