JP2013507990A - ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス - Google Patents

ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス Download PDF

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JP2013507990A
JP2013507990A JP2012536963A JP2012536963A JP2013507990A JP 2013507990 A JP2013507990 A JP 2013507990A JP 2012536963 A JP2012536963 A JP 2012536963A JP 2012536963 A JP2012536963 A JP 2012536963A JP 2013507990 A JP2013507990 A JP 2013507990A
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義裕 河岡
泰介 堀本
晋 村上
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ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション
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JP2012536963A 2009-10-26 2010-10-26 ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス Pending JP2013507990A (ja)

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US25479509P 2009-10-26 2009-10-26
US61/254,795 2009-10-26
PCT/US2010/054128 WO2011056591A1 (en) 2009-10-26 2010-10-26 High titer recombinant influenza viruses with enhanced replication in vero cells

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JP2016053990A Active JP6375329B2 (ja) 2009-10-26 2016-03-17 ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス

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Cited By (15)

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JP2016524915A (ja) * 2013-07-15 2016-08-22 ウィスコンシン アルムニ リサーチ ファンデイション Mdck、ベロ細胞又は卵内で増強された複製を有する高力価の組換えインフルエンザウイルス
US10633422B2 (en) 2015-06-01 2020-04-28 Wisconsin Alumni Research Foundation (Warf) Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA
JP2021500891A (ja) * 2017-10-25 2021-01-14 ウィスコンシン アルムニ リサーチ ファンデイション 卵における複製のための安定化されたhaを有する組換えインフルエンザウイルス
US11046934B2 (en) 2014-06-20 2021-06-29 Wisconsin Alumni Research Foundation (Warf) Mutations that confer genetic stability to additional genes in influenza viruses
US11241492B2 (en) 2019-01-23 2022-02-08 Wisconsin Alumni Research Foundation (Warf) Mutations that confer genetic stability to genes in influenza viruses
US11390649B2 (en) 2019-05-01 2022-07-19 Wisconsin Alumni Research Foundation (Warf) Influenza virus replication for vaccine development
US11807872B2 (en) 2019-08-27 2023-11-07 Wisconsin Alumni Research Foundation (Warf) Recombinant influenza viruses with stabilized HA for replication in eggs
US11851648B2 (en) 2019-02-08 2023-12-26 Wisconsin Alumni Research Foundation (Warf) Humanized cell line
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US12144857B2 (en) 2018-08-20 2024-11-19 Wisconsin Alumni Research Foundation (Warf) Vectors for eliciting immune responses to non-dominant epitopes in the hemagglutinin (HA) protein
US12290562B2 (en) 2020-03-25 2025-05-06 Wisconsin Alumni Research Foundation (Warf) Recombinant multivalent influenza viruses
US12343390B2 (en) 2018-08-07 2025-07-01 Wisconsin Alumni Research Foundation (Warf) Recombinant biologically contained filovirus vaccine
US12365880B2 (en) 2020-01-24 2025-07-22 The University Of Tokyo Recombinant influenza viruses with stabilized NA
US12364748B2 (en) 2016-02-19 2025-07-22 Wisconsin Alumni Research Foundation (Warf) Influenza B virus replication for vaccine development
US12410409B2 (en) 2011-08-26 2025-09-09 Wisconsin Alumni Research Foundation (Warf) Influenza viruses with mutant PB2 gene segment as live attenuated vaccines

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CN103608453B (zh) 2012-03-02 2018-07-24 思齐乐 流感病毒重配
US10927151B2 (en) * 2015-06-09 2021-02-23 Sanofi Pasteur Inc. Methods of optimizing nucleotide sequences encoding engineered influenza proteins
US9890363B2 (en) 2015-07-06 2018-02-13 Wisconsin Alumni Research Foundation (Warf) Influenza virus replication for vaccine development
JP7756911B2 (ja) * 2019-06-07 2025-10-21 フルゲン, インコーポレイテッド インフルエンザウイルスバックボーン
EP4185601A4 (en) 2020-07-21 2024-10-30 Flugen, Inc. SKELETON OF THE INFLUENZA VIRUS
CA3186408A1 (en) * 2020-07-21 2022-01-27 Michael J. Moser Vaccine using m2/bm2-deficient influenza vectors

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US20180340152A1 (en) 2018-11-29
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