JP2013505223A5 - - Google Patents

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Publication number
JP2013505223A5
JP2013505223A5 JP2012529298A JP2012529298A JP2013505223A5 JP 2013505223 A5 JP2013505223 A5 JP 2013505223A5 JP 2012529298 A JP2012529298 A JP 2012529298A JP 2012529298 A JP2012529298 A JP 2012529298A JP 2013505223 A5 JP2013505223 A5 JP 2013505223A5
Authority
JP
Japan
Prior art keywords
bispecific antibody
dose
epcamxcd3 bispecific
period
epcamxcd3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012529298A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013505223A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2010/063795 external-priority patent/WO2011033105A1/en
Publication of JP2013505223A publication Critical patent/JP2013505223A/ja
Publication of JP2013505223A5 publication Critical patent/JP2013505223A5/ja
Pending legal-status Critical Current

Links

JP2012529298A 2009-09-18 2010-09-20 EpCAMxCD3二重特異性抗体を投与するための投与計画 Pending JP2013505223A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US24365109P 2009-09-18 2009-09-18
US61/243,651 2009-09-18
EP09170715.8 2009-09-18
EP09170715 2009-09-18
US34414710P 2010-06-01 2010-06-01
EP10164596.8 2010-06-01
EP10164596 2010-06-01
US61/344,147 2010-06-01
PCT/EP2010/063795 WO2011033105A1 (en) 2009-09-18 2010-09-20 Dosage regimen for administering an epcamxcd3 bispecific antibody

Publications (2)

Publication Number Publication Date
JP2013505223A JP2013505223A (ja) 2013-02-14
JP2013505223A5 true JP2013505223A5 (enExample) 2013-11-28

Family

ID=43127167

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012529298A Pending JP2013505223A (ja) 2009-09-18 2010-09-20 EpCAMxCD3二重特異性抗体を投与するための投与計画

Country Status (15)

Country Link
US (1) US20120244161A1 (enExample)
EP (1) EP2477653A1 (enExample)
JP (1) JP2013505223A (enExample)
KR (1) KR20120083359A (enExample)
CN (1) CN102711825A (enExample)
AU (1) AU2010297258A1 (enExample)
BR (1) BR112012008345A2 (enExample)
CA (1) CA2774732A1 (enExample)
IL (1) IL218637A0 (enExample)
IN (1) IN2012DN03172A (enExample)
MX (1) MX2012003175A (enExample)
NZ (1) NZ598601A (enExample)
RU (1) RU2012115480A (enExample)
SG (2) SG10201405434VA (enExample)
WO (1) WO2011033105A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102293537B1 (ko) * 2016-03-30 2021-08-25 린톤 퍼시픽 아게 요로의 신생물을 치료하는데 사용하기 위한 다중특이적 항체

Families Citing this family (20)

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WO2012158818A2 (en) * 2011-05-16 2012-11-22 Fabion Pharmaceuticals, Inc. Multi-specific fab fusion proteins and methods of use
AR089114A1 (es) 2011-12-09 2014-07-30 Amgen Res Munich Gmbh PREVENCION DE LOS EFECTOS ADVERSOS CAUSADOS POR LOS ANTICUERPOS BIESPECIFICOS EpCAMxCD3
GB201302447D0 (en) 2013-02-12 2013-03-27 Oxford Biotherapeutics Ltd Therapeutic and diagnostic target
DK2956477T4 (da) 2013-02-15 2024-04-15 Bioverativ Therapeutics Inc Optimeret faktor viii-gen
CN110845618A (zh) * 2013-02-26 2020-02-28 罗切格利卡特公司 双特异性t细胞活化抗原结合分子
ES2728668T3 (es) * 2014-01-08 2019-10-28 Univ Leland Stanford Junior Terapia dirigida para el cáncer de pulmón de células pequeñas
US11008561B2 (en) 2014-06-30 2021-05-18 Bioverativ Therapeutics Inc. Optimized factor IX gene
IL319047A (en) * 2015-08-28 2025-04-01 Amunix Operating Inc Chimeric polypeptide composition and methods for its preparation and use
PT3377103T (pt) * 2015-11-19 2021-05-26 Revitope Ltd Complementação de fragmento de anticorpo funcional para um sistema de dois componentes para exterminação redirecionada de células indesejadas
KR20180118659A (ko) 2016-02-01 2018-10-31 바이오버라티브 테라퓨틱스 인크. 최적화된 viii 인자 유전자
US12128102B2 (en) 2016-03-08 2024-10-29 Takeda Pharmaceutical Company Limited Constrained conditionally activated binding proteins
CN109476756B (zh) 2016-03-15 2022-05-31 埃泰美德(香港)有限公司 一种多特异性Fab融合蛋白及其用途
EP3409322A1 (en) * 2017-06-01 2018-12-05 F. Hoffmann-La Roche AG Treatment method
IL273119B2 (en) 2017-09-08 2023-10-01 Maverick Therapeutics Inc Binding proteins are activated under limited conditions
US12460000B2 (en) 2018-09-07 2025-11-04 Itabmed (Hk) Limited Anti-CD19 and anti-CD3 bispecific antigen binding proteins and uses thereof
WO2020132810A1 (en) 2018-12-24 2020-07-02 Generon (Shanghai) Corporation Ltd. Multispecific antigen binding proteins capable of binding cd19 and cd3, and use thereof
EP4592313A3 (en) 2019-03-05 2025-11-19 Takeda Pharmaceutical Company Limited Constrained conditionally activated binding proteins
TW202126284A (zh) 2019-09-30 2021-07-16 美商百歐維拉提夫治療公司 慢病毒載體配製物
WO2021262963A1 (en) 2020-06-24 2021-12-30 Bioverativ Therapeutics Inc. Methods for the removal of free factor viii from preparations of lentiviral vectors modified to express said protein
CN120818062A (zh) * 2021-11-19 2025-10-21 武汉友芝友生物制药股份有限公司 双特异性抗体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU612370B2 (en) 1987-05-21 1991-07-11 Micromet Ag Targeted multifunctional proteins
JP4948174B2 (ja) 2003-10-16 2012-06-06 マイクロメット アクツィエン ゲゼルシャフト 多重特異的脱免疫cd3−結合物質
JP5129122B2 (ja) * 2005-04-26 2013-01-23 トリオン ファーマ ゲーエムベーハー 癌治療のための抗体およびグルココルチコイドの組み合わせ

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102293537B1 (ko) * 2016-03-30 2021-08-25 린톤 퍼시픽 아게 요로의 신생물을 치료하는데 사용하기 위한 다중특이적 항체
KR102435747B1 (ko) * 2016-03-30 2022-08-23 린톤 퍼시픽 아게 요로의 신생물을 치료하는데 사용하기 위한 다중특이적 항체

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