JP2013502931A5 - - Google Patents
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- JP2013502931A5 JP2013502931A5 JP2012527011A JP2012527011A JP2013502931A5 JP 2013502931 A5 JP2013502931 A5 JP 2013502931A5 JP 2012527011 A JP2012527011 A JP 2012527011A JP 2012527011 A JP2012527011 A JP 2012527011A JP 2013502931 A5 JP2013502931 A5 JP 2013502931A5
- Authority
- JP
- Japan
- Prior art keywords
- mir
- mirna
- patient
- item
- lung cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23797209P | 2009-08-28 | 2009-08-28 | |
| US61/237,972 | 2009-08-28 | ||
| PCT/US2010/046916 WO2011025919A1 (en) | 2009-08-28 | 2010-08-27 | Mirna biomarkers of lung disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013502931A JP2013502931A (ja) | 2013-01-31 |
| JP2013502931A5 true JP2013502931A5 (https=) | 2013-10-10 |
| JP5995721B2 JP5995721B2 (ja) | 2016-09-21 |
Family
ID=43625469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012527011A Expired - Fee Related JP5995721B2 (ja) | 2009-08-28 | 2010-08-27 | 肺疾患のmiRNAバイオマーカー |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8735074B2 (https=) |
| EP (2) | EP2470897A4 (https=) |
| JP (1) | JP5995721B2 (https=) |
| CN (1) | CN102725632A (https=) |
| WO (1) | WO2011025919A1 (https=) |
Families Citing this family (77)
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| JP2010538680A (ja) | 2007-09-19 | 2010-12-16 | ザ トラスティーズ オブ ボストン ユニバーシティー | 肺疾患に対する薬剤開発のための新規経路の同定 |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
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| EP2505663A1 (en) | 2011-03-30 | 2012-10-03 | IFOM Fondazione Istituto Firc di Oncologia Molecolare | A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting miRNAs in biologic fluids |
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| US9850541B2 (en) | 2011-12-19 | 2017-12-26 | Valley Health System | Methods and kits for detecting subjects at risk of having cancer |
| JP2015512249A (ja) | 2012-03-19 | 2015-04-27 | プレスティズィアPrestizia | 循環から採取される身体試料中のウイルス、特に、hivの親和性及び受容体使用の決定方法 |
| CN102743765A (zh) * | 2012-05-24 | 2012-10-24 | 上海大学 | 非小细胞肺癌中miR-10a基因的应用 |
| EP3626308A1 (en) | 2013-03-14 | 2020-03-25 | Veracyte, Inc. | Methods for evaluating copd status |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| CN103602678B (zh) * | 2013-06-18 | 2016-02-10 | 潘世扬 | 非小细胞肺癌预后检测组合物及其应用 |
| CN103751801A (zh) * | 2013-09-10 | 2014-04-30 | 上海大学 | 非小细胞肺癌中miR-143基因的应用 |
| CN103555724B (zh) * | 2013-10-24 | 2015-08-05 | 浙江理工大学 | 2型糖尿病的血清miRNA生物标志物及其应用 |
| JP6930832B2 (ja) | 2013-11-18 | 2021-09-01 | ディアミール, エルエルシーDiamir, Llc | パーキンソン病(PD)の検出およびモニタリングのための、体液からのmiRNAを使用する方法 |
| CN103667459A (zh) * | 2013-11-26 | 2014-03-26 | 上海中医药大学附属岳阳中西医结合医院 | 微小核苷酸在高血压诊断和制备降血压药物中的应用 |
| AU2014375224A1 (en) * | 2014-01-05 | 2016-07-28 | Biomirna Holdings Ltd | Lung cancer determinations using miRNA ratios |
| US10781491B2 (en) | 2014-03-16 | 2020-09-22 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | MicroRNA signature for predicting progression of Barrett's esophagus |
| CN103937826B (zh) * | 2014-04-04 | 2016-04-06 | 东华大学 | 一种中枢神经系统中特异表达miR-505的载体的制备方法 |
| FR3019901B1 (fr) * | 2014-04-09 | 2020-10-30 | Bio Rad Innovations | Marqueur de controle pour la mise en oeuvre de procedes d'analyse sur spots |
| RU2017101354A (ru) | 2014-06-18 | 2018-07-18 | Торэй Индастриз, Инк. | Набор или устройство для обнаружения рака легкого и способ обнаружения |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| CN104313142B (zh) * | 2014-10-16 | 2016-02-03 | 上海交通大学医学院附属仁济医院 | miRNA-30a作为标记分子在制备诊断试剂中的用途 |
| WO2016059241A2 (en) * | 2014-10-17 | 2016-04-21 | Biomirna Holdings Ltd. | Lung cancer diagnostics and therapeutics with mir-660 |
| EP3215170A4 (en) | 2014-11-05 | 2018-04-25 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| WO2016071729A1 (en) * | 2014-11-05 | 2016-05-12 | Biomirna Holdings, Ltd. | Methods of using micro-rna biomarkers for haemolysis detection |
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| CN104784704A (zh) * | 2015-05-01 | 2015-07-22 | 北京泱深生物信息技术有限公司 | 肺腺癌转移相关的组合物及其应用 |
| WO2016177343A1 (zh) * | 2015-05-05 | 2016-11-10 | 江苏命码生物科技有限公司 | 一种新的前体miRNA及其在肿瘤治疗中的应用 |
| CN105087794B (zh) * | 2015-08-17 | 2018-01-30 | 广东省结核病控制中心 | 一种检测结核病的试剂盒 |
| CN105457041B (zh) * | 2015-12-09 | 2020-09-08 | 上海大学 | miR-26a在非小细胞肺癌中的应用 |
| CN105400882B (zh) | 2015-12-15 | 2019-04-02 | 中国人民解放军第二军医大学 | 一种适用于后纵韧带骨化诊断的血清miRNA标志物及应用 |
| CN105561339B (zh) * | 2015-12-21 | 2019-02-22 | 江苏省人民医院 | 一种miRNA的组合制备抗非小细胞肺癌药物中的应用 |
| US10975436B2 (en) | 2016-01-05 | 2021-04-13 | Diamir, Llc | Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders |
| US11149313B2 (en) | 2016-03-21 | 2021-10-19 | Diamir, Llc | Methods of using miRNAs from bodily fluids for detection and differentiation of neurodegenerative diseases |
| EP4180531A3 (en) | 2016-05-12 | 2023-08-23 | Trustees of Boston University | Nasal epithelium gene expression signature and classifier for the prediction of lung cancer |
| ES2646826B1 (es) * | 2016-05-13 | 2018-10-01 | Servicio Andaluz De Salud | MicroARNs como biomarcadores para el diagnóstico del cáncer de pulmón |
| US10927417B2 (en) | 2016-07-08 | 2021-02-23 | Trustees Of Boston University | Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions |
| WO2018170622A1 (zh) * | 2017-03-18 | 2018-09-27 | 深圳市博奥康生物科技有限公司 | 一种同步下调微小rna-152和微小rna-185表达的方法 |
| US11535895B2 (en) | 2017-04-06 | 2022-12-27 | University Of Maryland, Baltimore | Methods of detecting lung cancer |
| CA3059119C (en) * | 2017-05-31 | 2024-01-23 | F. Hoffman-La Roche Ag | Multiplex pcr detection of alk, ret, and ros fusions |
| US11984224B2 (en) | 2017-05-31 | 2024-05-14 | Koninklijke Philips N.V. | Machine learning on raw medical imaging data for clinical decision support |
| BR112019028059A2 (pt) | 2017-06-29 | 2020-07-14 | Toray Industries, Inc. | kit para a detecção de câncer de pulmão, dispositivo para a detecção de câncer de pulmão e métodos para a detecção de câncer de pulmão |
| US10781487B2 (en) | 2017-07-24 | 2020-09-22 | Diamir, Llc | miRNA-based methods for detecting and monitoring aging |
| CN107841560A (zh) * | 2017-10-27 | 2018-03-27 | 广东省实验动物监测所 | 一种非小细胞肺癌miRNA检测试剂盒及其应用 |
| CN108220427B (zh) * | 2018-03-20 | 2021-09-28 | 南京大学 | 一种用于鉴别诊断BHD综合征与原发性自发性气胸的血浆microRNA标记物及应用 |
| CN108753770B (zh) * | 2018-06-01 | 2020-07-28 | 临沂大学 | 一种用于靶向肺癌治疗的基因纳米探针及其制备方法和应用 |
| CN108743521B (zh) * | 2018-06-01 | 2021-06-25 | 临沂大学 | 一种用于肺癌靶向治疗的rna纳米水凝胶及其制备方法和应用 |
| CN108841962B (zh) * | 2018-08-01 | 2021-11-19 | 博奥生物集团有限公司 | 一种非小细胞肺癌检测试剂盒及其应用 |
| KR102190910B1 (ko) * | 2019-05-24 | 2020-12-15 | 한국과학기술연구원 | miR-195 또는 miR-497를 활용한 폐암 치료제의 스크리닝 방법 |
| US11198912B2 (en) * | 2019-08-26 | 2021-12-14 | Liquid Lung Dx | Biomarkers for the diagnosis of lung cancers |
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| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| JP7392224B2 (ja) * | 2020-02-19 | 2023-12-06 | 国立医薬品食品衛生研究所長 | びまん性肺胞傷害型薬剤性間質性肺炎のmiRNA診断バイオマーカー |
| CN111455057B (zh) * | 2020-03-30 | 2021-10-26 | 中国医学科学院肿瘤医院 | 用于肺癌诊断的试剂盒、装置及方法 |
| US20240301504A1 (en) * | 2021-06-22 | 2024-09-12 | The Curators Of The University Of Missouri | Multianalyte biomarkers for lung cancer |
| CN113373216B (zh) * | 2021-07-13 | 2024-06-04 | 南京迈迪森亚生物科技有限公司 | 一种同时定量检测血清中3种急性心肌梗死相关microRNA荧光探针的制备方法 |
| CN114525331B (zh) * | 2021-11-23 | 2024-04-26 | 中山大学 | 一种快速识别重症肺炎的检测产品 |
| CN114767865A (zh) * | 2022-05-12 | 2022-07-22 | 中南大学湘雅医院 | 血浆外泌体对aaad伴肺损伤药物研制中应用 |
| CN117106919B (zh) * | 2023-10-25 | 2024-01-23 | 上海秤信生物科技有限公司 | 外泌体miRNA组合在早期肺癌检测中的应用 |
| CN119433026B (zh) * | 2023-11-17 | 2025-10-31 | 北京热景生物技术股份有限公司 | 一种基于外泌体miRNA的肝癌诊断标志物及其应用 |
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-
2010
- 2010-08-27 EP EP10812641.8A patent/EP2470897A4/en not_active Withdrawn
- 2010-08-27 CN CN201080048520XA patent/CN102725632A/zh active Pending
- 2010-08-27 EP EP13194030.6A patent/EP2775300A3/en not_active Withdrawn
- 2010-08-27 JP JP2012527011A patent/JP5995721B2/ja not_active Expired - Fee Related
- 2010-08-27 US US12/870,245 patent/US8735074B2/en not_active Expired - Fee Related
- 2010-08-27 WO PCT/US2010/046916 patent/WO2011025919A1/en not_active Ceased
-
2014
- 2014-04-11 US US14/251,156 patent/US20140274791A1/en not_active Abandoned
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