JP2013501008A - 抗ウイルス性化合物ならびにそれを含む医薬組成物 - Google Patents

抗ウイルス性化合物ならびにそれを含む医薬組成物 Download PDF

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Publication number
JP2013501008A
JP2013501008A JP2012523184A JP2012523184A JP2013501008A JP 2013501008 A JP2013501008 A JP 2013501008A JP 2012523184 A JP2012523184 A JP 2012523184A JP 2012523184 A JP2012523184 A JP 2012523184A JP 2013501008 A JP2013501008 A JP 2013501008A
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nitro
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English (en)
Japanese (ja)
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カオ、イツン、リチャード
ヤン、ダン
ユエン、クォギョン
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Versitech Ltd
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Versitech Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP2012523184A 2009-08-05 2010-08-05 抗ウイルス性化合物ならびにそれを含む医薬組成物 Pending JP2013501008A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23143109P 2009-08-05 2009-08-05
US61/231,431 2009-08-05
PCT/CN2010/001187 WO2011015037A1 (en) 2009-08-05 2010-08-05 Antiviral compounds and methods of making and using there of cross reference to related applications

Publications (1)

Publication Number Publication Date
JP2013501008A true JP2013501008A (ja) 2013-01-10

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JP2012523184A Pending JP2013501008A (ja) 2009-08-05 2010-08-05 抗ウイルス性化合物ならびにそれを含む医薬組成物

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EP (1) EP2462138B1 (enExample)
JP (1) JP2013501008A (enExample)
KR (1) KR20120092567A (enExample)
CN (1) CN102596946B (enExample)
AU (1) AU2010281265A1 (enExample)
BR (1) BR112012002331A2 (enExample)
CA (1) CA2770140A1 (enExample)
IL (1) IL217745A0 (enExample)
IN (1) IN2012DN01254A (enExample)
MX (1) MX2012001504A (enExample)
RU (1) RU2012104214A (enExample)
SG (1) SG178106A1 (enExample)
WO (1) WO2011015037A1 (enExample)

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JP2016527259A (ja) * 2013-07-30 2016-09-08 ヤンセン・サイエンシズ・アイルランド・ユーシー Ｒｓｖ抗ウイルス化合物としての置換ピリジンピペラジニルアナログ

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CN102432555A (zh) * 2011-09-09 2012-05-02 中国科学院广州生物医药与健康研究院 1,2,3-三氮唑-4（5）羧酰胺类化合物及其应用
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WO2011015037A1 (en) 2011-02-10
AU2010281265A2 (en) 2012-04-05
SG178106A1 (en) 2012-03-29
MX2012001504A (es) 2012-06-01
EP2462138B1 (en) 2014-09-24
AU2010281265A1 (en) 2012-03-22
RU2012104214A (ru) 2013-09-10
BR112012002331A2 (pt) 2019-09-24
IN2012DN01254A (enExample) 2015-05-15
CN102596946B (zh) 2015-06-17
KR20120092567A (ko) 2012-08-21
EP2462138A1 (en) 2012-06-13
IL217745A0 (en) 2012-03-29
CA2770140A1 (en) 2011-02-10
EP2462138A4 (en) 2013-01-23
CN102596946A (zh) 2012-07-18

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