JP2013500006A5 - - Google Patents
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- JP2013500006A5 JP2013500006A5 JP2012521593A JP2012521593A JP2013500006A5 JP 2013500006 A5 JP2013500006 A5 JP 2013500006A5 JP 2012521593 A JP2012521593 A JP 2012521593A JP 2012521593 A JP2012521593 A JP 2012521593A JP 2013500006 A5 JP2013500006 A5 JP 2013500006A5
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- 210000004027 cell Anatomy 0.000 claims 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 12
- 230000000694 effects Effects 0.000 claims 12
- 230000001419 dependent effect Effects 0.000 claims 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 9
- 210000005253 yeast cell Anatomy 0.000 claims 7
- 102100036669 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic Human genes 0.000 claims 5
- 150000001720 carbohydrates Chemical class 0.000 claims 5
- 150000007523 nucleic acids Chemical group 0.000 claims 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 4
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 230000035772 mutation Effects 0.000 claims 4
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 claims 4
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 238000003786 synthesis reaction Methods 0.000 claims 4
- 102000008146 Acetate-CoA ligase Human genes 0.000 claims 3
- 108010049926 Acetate-CoA ligase Proteins 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 108010041921 Glycerolphosphate Dehydrogenase Proteins 0.000 claims 3
- 108010081577 aldehyde dehydrogenase (NAD(P)+) Proteins 0.000 claims 3
- 238000002360 preparation method Methods 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims 2
- 102000007698 Alcohol dehydrogenase Human genes 0.000 claims 2
- 241000722885 Brettanomyces Species 0.000 claims 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims 2
- XYZZKVRWGOWVGO-UHFFFAOYSA-N Glycerol-phosphate Chemical compound OP(O)(O)=O.OCC(O)CO XYZZKVRWGOWVGO-UHFFFAOYSA-N 0.000 claims 2
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 claims 2
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 claims 2
- 241000235070 Saccharomyces Species 0.000 claims 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 1
- 101710088194 Dehydrogenase Proteins 0.000 claims 1
- 229930091371 Fructose Natural products 0.000 claims 1
- 239000005715 Fructose Substances 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 101150004714 GPP1 gene Proteins 0.000 claims 1
- 101150059691 GPP2 gene Proteins 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 102100030395 Glycerol-3-phosphate dehydrogenase, mitochondrial Human genes 0.000 claims 1
- 229920002488 Hemicellulose Polymers 0.000 claims 1
- 101001072574 Homo sapiens Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic Proteins 0.000 claims 1
- 101001009678 Homo sapiens Glycerol-3-phosphate dehydrogenase, mitochondrial Proteins 0.000 claims 1
- 235000014663 Kluyveromyces fragilis Nutrition 0.000 claims 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 1
- 244000253911 Saccharomyces fragilis Species 0.000 claims 1
- 235000018368 Saccharomyces fragilis Nutrition 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 229930182830 galactose Natural products 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 229940031154 kluyveromyces marxianus Drugs 0.000 claims 1
- 239000002029 lignocellulosic biomass Substances 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 230000009261 transgenic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09166360A EP2277989A1 (en) | 2009-07-24 | 2009-07-24 | Fermentative glycerol-free ethanol production |
| EP09166360.9 | 2009-07-24 | ||
| PCT/NL2010/050475 WO2011010923A1 (en) | 2009-07-24 | 2010-07-23 | Fermentative glycerol-free ethanol production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013500006A JP2013500006A (ja) | 2013-01-07 |
| JP2013500006A5 true JP2013500006A5 (https=) | 2013-08-22 |
| JP5836271B2 JP5836271B2 (ja) | 2015-12-24 |
Family
ID=41460190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521593A Active JP5836271B2 (ja) | 2009-07-24 | 2010-07-23 | グリセロールを含まない発酵によるエタノール生成 |
Country Status (15)
| Country | Link |
|---|---|
| US (11) | US8795998B2 (https=) |
| EP (4) | EP2277989A1 (https=) |
| JP (1) | JP5836271B2 (https=) |
| CN (1) | CN102712895B (https=) |
| AU (1) | AU2010275085A1 (https=) |
| BR (1) | BR112012001642B1 (https=) |
| CA (1) | CA2768897C (https=) |
| DK (1) | DK2456851T3 (https=) |
| EA (1) | EA201270187A1 (https=) |
| ES (1) | ES2706653T3 (https=) |
| MX (1) | MX2012001062A (https=) |
| PL (1) | PL2456851T3 (https=) |
| UA (1) | UA107467C2 (https=) |
| WO (1) | WO2011010923A1 (https=) |
| ZA (1) | ZA201200703B (https=) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2277989A1 (en) | 2009-07-24 | 2011-01-26 | Technische Universiteit Delft | Fermentative glycerol-free ethanol production |
| US9605269B2 (en) * | 2010-05-05 | 2017-03-28 | Lallemand Hungary Liquidity Management Llc | Detoxification of biomass derived acetate via metabolic conversion to ethanol, acetone, isopropanol, or ethyl acetate |
| WO2011149353A1 (en) * | 2010-05-27 | 2011-12-01 | C5 Yeast Company B.V. | Yeast strains engineered to produce ethanol from acetic acid and glycerol |
| EP2576762A4 (en) | 2010-06-03 | 2013-12-04 | Mascoma Corp | YEAST FOR THE EXPRESSION OF SACCHAROLYTIC ENZYMES FOR CONSOLIDATED BIOVERIC PROCESSING USING STARCH AND CELLULOSE |
| CA2832279C (en) * | 2011-04-05 | 2024-03-05 | Mascoma Corporation | Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors |
| US9890398B2 (en) | 2011-10-24 | 2018-02-13 | Toyota Jidosha Kabushiki Kaisha | Method for producing ethanol using recombinant yeast |
| CN104039974B (zh) * | 2011-11-09 | 2016-10-12 | 阿迈瑞斯公司 | 乙酰辅酶a衍生的类异戊二烯的生产 |
| KR20140099251A (ko) * | 2011-11-30 | 2014-08-11 | 디에스엠 아이피 어셋츠 비.브이. | 아세트산 및 글리세롤로부터 에탄올을 생성하도록 합성된 이스트 스트레인 |
| CA2857498A1 (en) * | 2011-11-30 | 2013-09-26 | Mascoma Corporation | Engineering an increase in ethanol production by altering cofactor specificity |
| IN2015DN01041A (https=) * | 2012-08-28 | 2015-06-26 | Dsm Ip Assets Bv | |
| WO2014033019A1 (en) * | 2012-08-28 | 2014-03-06 | Dsm Ip Assets B.V. | Yeast strains engineered to produce ethanol from acetate |
| EP2890784A1 (en) | 2012-08-29 | 2015-07-08 | Lallemand Hungary Liquidity Management LLC | Expression of enzymes in yeast for lignocellulose derived oligomer cbp |
| EP3498829A1 (en) | 2012-11-09 | 2019-06-19 | Lallemand Hungary Liquidity Management LLC | Method for acetate consumption during ethanolic fermentation of cellulosic feedstocks |
| CN109536398B (zh) | 2013-02-22 | 2023-08-04 | 帝斯曼知识产权资产管理有限公司 | 用于产量增加的方法中的重组体微生物 |
| CN114774477B (zh) * | 2013-02-27 | 2024-04-09 | 丰田自动车株式会社 | 使用了重组酵母的乙醇的制造方法 |
| AU2014244216A1 (en) | 2013-03-14 | 2015-09-24 | E.I. Du Pont De Nemours And Company | Glycerol 3- phosphate dehydrogenase for butanol production |
| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| CA2905133C (en) | 2013-03-15 | 2024-03-05 | Lallemand Hungary Liquidity Management Llc | Methods for regulating nitrogen metabolism during the production of ethanol from corn by metabolically engineered yeast strains |
| WO2014180820A2 (en) * | 2013-05-08 | 2014-11-13 | Dsm Ip Assets B.V. | Gpd- yeast strains with improved osmotolerance |
| MX377110B (es) | 2013-08-15 | 2025-03-07 | Danstar Ferment Ag | Metodos para la mejora del rendimiento y produccion de producto en un microorganismo a traves del reciclaje de glicerol. |
| AR097480A1 (es) | 2013-08-29 | 2016-03-16 | Dsm Ip Assets Bv | Células de levadura convertidoras de glicerol y ácido acético con una conversión de ácido acético mejorada |
| BR112016009416A2 (pt) | 2013-10-28 | 2017-10-03 | Danisco Us Inc | Levedura seca ativa geneticamente modificada de grande escala |
| KR102255306B1 (ko) * | 2013-11-15 | 2021-05-25 | 삼성전자주식회사 | 아세트알데히드 데히드로게나제를 포함하는 락테이트 생산능을 갖는 유전적으로 조작된 효모 세포, 그를 제조하는 방법 및 그를 사용하여 락테이트를 생산하는 방법 |
| US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
| MX2016011984A (es) * | 2014-03-21 | 2017-04-27 | Novozymes As | Procesos para producir etanol y levadura. |
| EP3122876B1 (en) | 2014-03-28 | 2020-11-25 | Danisco US Inc. | Altered host cell pathway for improved ethanol production |
| KR20160012561A (ko) * | 2014-07-24 | 2016-02-03 | 삼성전자주식회사 | Erg5의 활성이 증가되도록 유전적으로 조작된, 내산성을 갖는 효모 세포 및 그를 이용하여 락테이트를 생산하는 방법 |
| AU2016235802B2 (en) | 2015-03-20 | 2022-03-31 | Microbiogen Pty. Ltd. | Processes for producing ethanol and ethanol producing yeast |
| CN107636144B (zh) | 2015-05-22 | 2021-02-19 | 帝斯曼知识产权资产管理有限公司 | 消耗乙酸盐/酯的酵母细胞 |
| MY186400A (en) * | 2015-10-06 | 2021-07-22 | Dsm Ip Assets Bv | Eukaryotic cell with increased production of fermentation product |
| BR112018072150A2 (pt) * | 2016-04-28 | 2019-02-12 | Danisco Us Inc. | equilíbrio de redox em levedura |
| WO2017216136A1 (en) | 2016-06-14 | 2017-12-21 | Dsm Ip Assets B.V. | Recombinant yeast cell |
| JP6447583B2 (ja) * | 2016-06-24 | 2019-01-09 | トヨタ自動車株式会社 | 組換え酵母、及びそれを用いたエタノールの製造方法 |
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| BR112019019701A2 (pt) | 2017-03-24 | 2020-07-14 | Danisco Us Inc. | redução de acetato e glicerol em levedura modificada que tem um caminho de produção de etanol exógeno |
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| US11414683B2 (en) * | 2017-09-26 | 2022-08-16 | Dsm Ip Assets B.V. | Acetic acid consuming strain |
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| EP3938381A1 (en) | 2019-03-14 | 2022-01-19 | Danisco US Inc. | Over-expression of cytochrome b2 in yeast for increased ethanol production |
| EP3938519A1 (en) | 2019-03-14 | 2022-01-19 | Danisco US Inc. | Over-expression of fumarate-succinate transporter in yeast for increased ethanol and reduced acetate production |
| BR112021026259A2 (pt) | 2019-06-24 | 2022-03-03 | Danisco Us Inc | Interrupção de efetores cdc42 em levedura para produção aumentada de álcool e lisina |
| CN114302958B (zh) | 2019-06-24 | 2024-12-27 | 丹尼斯科美国公司 | 用于增加发酵联产物中赖氨酸含量的经修饰的酵母和方法 |
| BR112021026542A2 (pt) | 2019-06-28 | 2022-05-17 | Danisco Us Inc | Células de levedura modificadas que superexpressam as proteínas endógenas selecionadas |
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| US12416026B2 (en) | 2019-08-29 | 2025-09-16 | Danisco Us Inc. | Expression of beta-glucosidase in yeast for improved ethanol production |
| US20220380813A1 (en) | 2019-11-08 | 2022-12-01 | Dsm Ip Assets B.V. | Process for producing ethanol |
| WO2021108464A1 (en) | 2019-11-26 | 2021-06-03 | Danisco Us Inc. | Reduction in acetate production by yeast over-expressing mig polypeptides |
| US20230116556A1 (en) | 2020-01-23 | 2023-04-13 | Danisco Us Inc. | Increased ethanol production by overexpression of jid1 in yeast |
| US20230374443A1 (en) | 2020-10-05 | 2023-11-23 | Dsm Ip Assets B.V. | Saccharomyces yeast cell and fermentation process using such |
| CN117897475A (zh) * | 2021-04-05 | 2024-04-16 | 英联马利公司 | 用于乙醇生产的酵母菌株的开发 |
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2009
- 2009-07-24 EP EP09166360A patent/EP2277989A1/en not_active Withdrawn
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- 2010-07-23 BR BR112012001642A patent/BR112012001642B1/pt active IP Right Grant
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