JP2013500006A5 - - Google Patents
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- JP2013500006A5 JP2013500006A5 JP2012521593A JP2012521593A JP2013500006A5 JP 2013500006 A5 JP2013500006 A5 JP 2013500006A5 JP 2012521593 A JP2012521593 A JP 2012521593A JP 2012521593 A JP2012521593 A JP 2012521593A JP 2013500006 A5 JP2013500006 A5 JP 2013500006A5
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- 210000004027 cell Anatomy 0.000 claims 27
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 12
- 230000000694 effects Effects 0.000 claims 12
- 230000001419 dependent effect Effects 0.000 claims 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 9
- 210000005253 yeast cell Anatomy 0.000 claims 7
- 102100036669 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic Human genes 0.000 claims 5
- 150000001720 carbohydrates Chemical class 0.000 claims 5
- 150000007523 nucleic acids Chemical group 0.000 claims 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 4
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 230000035772 mutation Effects 0.000 claims 4
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 claims 4
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 238000003786 synthesis reaction Methods 0.000 claims 4
- 102000008146 Acetate-CoA ligase Human genes 0.000 claims 3
- 108010049926 Acetate-CoA ligase Proteins 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 108010041921 Glycerolphosphate Dehydrogenase Proteins 0.000 claims 3
- 108010081577 aldehyde dehydrogenase (NAD(P)+) Proteins 0.000 claims 3
- 238000002360 preparation method Methods 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims 2
- 102000007698 Alcohol dehydrogenase Human genes 0.000 claims 2
- 241000722885 Brettanomyces Species 0.000 claims 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims 2
- XYZZKVRWGOWVGO-UHFFFAOYSA-N Glycerol-phosphate Chemical compound OP(O)(O)=O.OCC(O)CO XYZZKVRWGOWVGO-UHFFFAOYSA-N 0.000 claims 2
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 claims 2
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 claims 2
- 241000235070 Saccharomyces Species 0.000 claims 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 1
- 101710088194 Dehydrogenase Proteins 0.000 claims 1
- 229930091371 Fructose Natural products 0.000 claims 1
- 239000005715 Fructose Substances 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 101150004714 GPP1 gene Proteins 0.000 claims 1
- 101150059691 GPP2 gene Proteins 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- 102100030395 Glycerol-3-phosphate dehydrogenase, mitochondrial Human genes 0.000 claims 1
- 229920002488 Hemicellulose Polymers 0.000 claims 1
- 101001072574 Homo sapiens Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic Proteins 0.000 claims 1
- 101001009678 Homo sapiens Glycerol-3-phosphate dehydrogenase, mitochondrial Proteins 0.000 claims 1
- 235000014663 Kluyveromyces fragilis Nutrition 0.000 claims 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 1
- 244000253911 Saccharomyces fragilis Species 0.000 claims 1
- 235000018368 Saccharomyces fragilis Nutrition 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 1
- PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 229930182830 galactose Natural products 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 229940031154 kluyveromyces marxianus Drugs 0.000 claims 1
- 239000002029 lignocellulosic biomass Substances 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 239000001814 pectin Substances 0.000 claims 1
- 229920001277 pectin Polymers 0.000 claims 1
- 235000010987 pectin Nutrition 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 230000009261 transgenic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09166360.9 | 2009-07-24 | ||
| EP09166360A EP2277989A1 (en) | 2009-07-24 | 2009-07-24 | Fermentative glycerol-free ethanol production |
| PCT/NL2010/050475 WO2011010923A1 (en) | 2009-07-24 | 2010-07-23 | Fermentative glycerol-free ethanol production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013500006A JP2013500006A (ja) | 2013-01-07 |
| JP2013500006A5 true JP2013500006A5 (https=) | 2013-08-22 |
| JP5836271B2 JP5836271B2 (ja) | 2015-12-24 |
Family
ID=41460190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521593A Active JP5836271B2 (ja) | 2009-07-24 | 2010-07-23 | グリセロールを含まない発酵によるエタノール生成 |
Country Status (15)
| Country | Link |
|---|---|
| US (11) | US8795998B2 (https=) |
| EP (4) | EP2277989A1 (https=) |
| JP (1) | JP5836271B2 (https=) |
| CN (1) | CN102712895B (https=) |
| AU (1) | AU2010275085A1 (https=) |
| BR (1) | BR112012001642B1 (https=) |
| CA (1) | CA2768897C (https=) |
| DK (1) | DK2456851T3 (https=) |
| EA (1) | EA201270187A1 (https=) |
| ES (1) | ES2706653T3 (https=) |
| MX (1) | MX2012001062A (https=) |
| PL (1) | PL2456851T3 (https=) |
| UA (1) | UA107467C2 (https=) |
| WO (1) | WO2011010923A1 (https=) |
| ZA (1) | ZA201200703B (https=) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2277989A1 (en) | 2009-07-24 | 2011-01-26 | Technische Universiteit Delft | Fermentative glycerol-free ethanol production |
| US9605269B2 (en) * | 2010-05-05 | 2017-03-28 | Lallemand Hungary Liquidity Management Llc | Detoxification of biomass derived acetate via metabolic conversion to ethanol, acetone, isopropanol, or ethyl acetate |
| WO2011149353A1 (en) * | 2010-05-27 | 2011-12-01 | C5 Yeast Company B.V. | Yeast strains engineered to produce ethanol from acetic acid and glycerol |
| WO2011153516A2 (en) | 2010-06-03 | 2011-12-08 | Mascoma Corporation | Yeast expressing saccharolytic enzymes for consolidated bioprocessing using starch and cellulose |
| EP3483279A1 (en) * | 2011-04-05 | 2019-05-15 | Lallemand Hungary Liquidity Management LLC | Methods for the improvement of product yield and production in a microorganism through the addition of alternate electron acceptors |
| US9890398B2 (en) | 2011-10-24 | 2018-02-13 | Toyota Jidosha Kabushiki Kaisha | Method for producing ethanol using recombinant yeast |
| EP2776571B1 (en) | 2011-11-09 | 2017-04-12 | Amyris, Inc. | Production of acetyl-coenzyme a derived isoprenoids |
| AU2012346662B2 (en) * | 2011-11-30 | 2016-07-28 | Danisco Us Inc. | Yeast strains engineered to produce ethanol from acetic acid and glycerol |
| WO2013141905A2 (en) * | 2011-11-30 | 2013-09-26 | Mascoma Corporation | Engineering an increase in ethanol production by altering cofactor specificity |
| WO2014033018A1 (en) * | 2012-08-28 | 2014-03-06 | Dsm Ip Assets B.V. | Yeast strains engineered to produce ethanol from acetate |
| IN2015DN01042A (https=) * | 2012-08-28 | 2015-06-26 | Dsm Ip Assets Bv | |
| EP2890784A1 (en) | 2012-08-29 | 2015-07-08 | Lallemand Hungary Liquidity Management LLC | Expression of enzymes in yeast for lignocellulose derived oligomer cbp |
| WO2014074895A2 (en) | 2012-11-09 | 2014-05-15 | Mascoma Corporation | Method for acetate consumption during ethanolic fermentation of cellulosic feedstocks |
| HUE060246T2 (hu) | 2013-02-22 | 2023-02-28 | Dsm Ip Assets Bv | Rekombináns mikroorganizmus, fokozott termékhozamú eljárásban történõ alkalmazásra |
| CN114774477B (zh) * | 2013-02-27 | 2024-04-09 | 丰田自动车株式会社 | 使用了重组酵母的乙醇的制造方法 |
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| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| CN105209600A (zh) * | 2013-03-15 | 2015-12-30 | 拉勒曼德匈牙利流动管理有限责任公司 | 通过代谢工程化的酵母菌株调节由玉米生产乙醇期间的氮代谢的方法 |
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| WO2015023989A1 (en) | 2013-08-15 | 2015-02-19 | Lallemand Hungary Liquidity Management Llc | Methods for the improvement of product yield and production in a microorganism through glycerol recycling |
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| BR112016009416A2 (pt) | 2013-10-28 | 2017-10-03 | Danisco Us Inc | Levedura seca ativa geneticamente modificada de grande escala |
| KR102255306B1 (ko) * | 2013-11-15 | 2021-05-25 | 삼성전자주식회사 | 아세트알데히드 데히드로게나제를 포함하는 락테이트 생산능을 갖는 유전적으로 조작된 효모 세포, 그를 제조하는 방법 및 그를 사용하여 락테이트를 생산하는 방법 |
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| WO2015143324A1 (en) * | 2014-03-21 | 2015-09-24 | Novozymes A/S | Processes for producing ethanol and yeast |
| EP3122876B1 (en) | 2014-03-28 | 2020-11-25 | Danisco US Inc. | Altered host cell pathway for improved ethanol production |
| KR20160012561A (ko) * | 2014-07-24 | 2016-02-03 | 삼성전자주식회사 | Erg5의 활성이 증가되도록 유전적으로 조작된, 내산성을 갖는 효모 세포 및 그를 이용하여 락테이트를 생산하는 방법 |
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| WO2017060195A1 (en) * | 2015-10-06 | 2017-04-13 | Dsm Ip Assets B.V. | Eukaryotic cell with increased production of fermentation product |
| CN109072201A (zh) * | 2016-04-28 | 2018-12-21 | 丹尼斯科美国公司 | 酵母中的氧化还原平衡 |
| CN109312296B (zh) * | 2016-06-14 | 2023-05-05 | 帝斯曼知识产权资产管理有限公司 | 重组酵母细胞 |
| JP6447583B2 (ja) * | 2016-06-24 | 2019-01-09 | トヨタ自動車株式会社 | 組換え酵母、及びそれを用いたエタノールの製造方法 |
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| US20190382739A1 (en) | 2017-01-18 | 2019-12-19 | Danisco Us Inc. | Modified yeast cells that overexpress a dna polymerase subunit |
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| WO2021022140A1 (en) | 2019-08-01 | 2021-02-04 | Danisco Us Inc | Over-expression of pho13 for increased ethanol production by yeast |
| WO2021022097A1 (en) | 2019-08-01 | 2021-02-04 | Danisco Us Inc | Over-expression of adh5p for increased ethanol production by yeast |
| MX2022002310A (es) | 2019-08-29 | 2022-06-02 | Danisco Us Inc | Expresión de beta-glucosidasa en levadura para producción mejorada de etanol. |
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| CN116348609A (zh) | 2020-10-05 | 2023-06-27 | 帝斯曼知识产权资产管理有限公司 | 酵母属酵母细胞及使用其的发酵方法 |
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| DK2262901T3 (en) * | 2008-03-05 | 2019-01-21 | Genomatica Inc | ORGANISMS PRODUCING PRIMARY ALCOHOL |
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