JP2012530719A5 - - Google Patents
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- Publication number
- JP2012530719A5 JP2012530719A5 JP2012516337A JP2012516337A JP2012530719A5 JP 2012530719 A5 JP2012530719 A5 JP 2012530719A5 JP 2012516337 A JP2012516337 A JP 2012516337A JP 2012516337 A JP2012516337 A JP 2012516337A JP 2012530719 A5 JP2012530719 A5 JP 2012530719A5
- Authority
- JP
- Japan
- Prior art keywords
- volatile
- formulation
- spreadable
- active ingredient
- siloxane matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000009472 formulation Methods 0.000 claims 17
- 239000000203 mixture Substances 0.000 claims 17
- 239000004480 active ingredient Substances 0.000 claims 11
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims 10
- 239000011159 matrix material Substances 0.000 claims 10
- 239000002243 precursor Substances 0.000 claims 9
- 238000002360 preparation method Methods 0.000 claims 7
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims 6
- 239000012752 auxiliary agent Substances 0.000 claims 6
- 238000000034 method Methods 0.000 claims 5
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims 4
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 claims 4
- MEJYDZQQVZJMPP-ULAWRXDQSA-N (3s,3ar,6r,6ar)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan Chemical compound CO[C@H]1CO[C@@H]2[C@H](OC)CO[C@@H]21 MEJYDZQQVZJMPP-ULAWRXDQSA-N 0.000 claims 3
- 229940043375 1,5-pentanediol Drugs 0.000 claims 3
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- 206010052428 Wound Diseases 0.000 claims 3
- 208000027418 Wounds and injury Diseases 0.000 claims 3
- 229940008099 dimethicone Drugs 0.000 claims 3
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 3
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims 3
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims 3
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- KLDXJTOLSGUMSJ-JGWLITMVSA-N Isosorbide Chemical class O[C@@H]1CO[C@@H]2[C@@H](O)CO[C@@H]21 KLDXJTOLSGUMSJ-JGWLITMVSA-N 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- ALEXXDVDDISNDU-JZYPGELDSA-N cortisol 21-acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O ALEXXDVDDISNDU-JZYPGELDSA-N 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229910021485 fumed silica Inorganic materials 0.000 claims 2
- 229960001067 hydrocortisone acetate Drugs 0.000 claims 2
- 229960002479 isosorbide Drugs 0.000 claims 2
- 229960001679 octinoxate Drugs 0.000 claims 2
- 229960003921 octisalate Drugs 0.000 claims 2
- FMJSMJQBSVNSBF-UHFFFAOYSA-N octocrylene Chemical group C=1C=CC=CC=1C(=C(C#N)C(=O)OCC(CC)CCCC)C1=CC=CC=C1 FMJSMJQBSVNSBF-UHFFFAOYSA-N 0.000 claims 2
- 229960000601 octocrylene Drugs 0.000 claims 2
- 229960001173 oxybenzone Drugs 0.000 claims 2
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 229920006037 cross link polymer Polymers 0.000 claims 1
- 125000000058 cyclopentadienyl group Chemical group C1(=CC=CC1)* 0.000 claims 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- ZSWFCLXCOIISFI-UHFFFAOYSA-N endo-cyclopentadiene Natural products C1C=CC=C1 ZSWFCLXCOIISFI-UHFFFAOYSA-N 0.000 claims 1
- 150000002148 esters Chemical group 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- 230000035876 healing Effects 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 150000003333 secondary alcohols Chemical class 0.000 claims 1
- 230000000475 sunscreen effect Effects 0.000 claims 1
- 239000000516 sunscreening agent Substances 0.000 claims 1
- 230000029663 wound healing Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/487,489 US20100322875A1 (en) | 2009-06-18 | 2009-06-18 | Silicone scar treatment preparation |
| US12/487,489 | 2009-06-18 | ||
| PCT/US2010/039181 WO2010148310A1 (en) | 2009-06-18 | 2010-06-18 | Silicone scar treatment preparation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015090815A Division JP6016974B2 (ja) | 2009-06-18 | 2015-04-27 | 瘢痕治療用シリコーン製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530719A JP2012530719A (ja) | 2012-12-06 |
| JP2012530719A5 true JP2012530719A5 (enExample) | 2013-08-01 |
| JP5740398B2 JP5740398B2 (ja) | 2015-06-24 |
Family
ID=43354570
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516337A Active JP5740398B2 (ja) | 2009-06-18 | 2010-06-18 | 瘢痕治療用シリコーン製剤 |
| JP2015090815A Active JP6016974B2 (ja) | 2009-06-18 | 2015-04-27 | 瘢痕治療用シリコーン製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015090815A Active JP6016974B2 (ja) | 2009-06-18 | 2015-04-27 | 瘢痕治療用シリコーン製剤 |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US20100322875A1 (enExample) |
| EP (1) | EP2442771B1 (enExample) |
| JP (2) | JP5740398B2 (enExample) |
| KR (1) | KR101543060B1 (enExample) |
| CN (1) | CN102802572B (enExample) |
| AU (1) | AU2010263031B2 (enExample) |
| BR (1) | BRPI1009689B1 (enExample) |
| CA (1) | CA2765964C (enExample) |
| CY (1) | CY1123227T1 (enExample) |
| DK (1) | DK2442771T3 (enExample) |
| ES (1) | ES2781649T3 (enExample) |
| HR (1) | HRP20200560T1 (enExample) |
| HU (1) | HUE048612T2 (enExample) |
| IL (1) | IL217056A (enExample) |
| LT (1) | LT2442771T (enExample) |
| MX (1) | MX2011013965A (enExample) |
| NZ (1) | NZ597335A (enExample) |
| PL (1) | PL2442771T3 (enExample) |
| PT (1) | PT2442771T (enExample) |
| RU (1) | RU2530657C2 (enExample) |
| SG (1) | SG176894A1 (enExample) |
| SI (1) | SI2442771T1 (enExample) |
| WO (1) | WO2010148310A1 (enExample) |
| ZA (1) | ZA201200353B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100322875A1 (en) * | 2009-06-18 | 2010-12-23 | Advanced Bio-Technologies, Inc. | Silicone scar treatment preparation |
| US9592241B2 (en) | 2011-12-27 | 2017-03-14 | Cmpd Licensing, Llc | Silicone-based composition for skin treatment |
| CN104254563B (zh) * | 2012-02-24 | 2017-09-12 | 大金工业株式会社 | 氟橡胶组合物 |
| EP2999339B1 (en) * | 2013-05-20 | 2019-06-19 | Zoetis Services LLC | Long-acting spiro-isoxazoline antiparasitic compositions |
| US9511034B1 (en) | 2013-12-09 | 2016-12-06 | Bio-Silicote, Inc. | Method for applying a skin treatment |
| US9226890B1 (en) | 2013-12-10 | 2016-01-05 | Englewood Lab, Llc | Polysilicone base for scar treatment |
| RS67297B1 (sr) | 2015-03-12 | 2025-11-28 | Cristcot Llc | Formulacija supozitorije hidrokortizon acetata za upotrebu u lečenju inflamatorne bolesti creva |
| TWI559923B (en) * | 2015-03-16 | 2016-12-01 | Amed Co Ltd | A composition of silicone gel for wound dressing |
| CN104784066A (zh) * | 2015-04-10 | 2015-07-22 | 浙江省诸暨市珠力神医用品有限公司 | 一种抗紫外线的硅凝胶组合物 |
| CN104814886A (zh) * | 2015-04-10 | 2015-08-05 | 浙江省诸暨市珠力神医用品有限公司 | 一种硅凝胶组合物 |
| GB201616088D0 (en) * | 2016-09-21 | 2016-11-02 | Avexxin As | Pharmaceutical composition |
| CA3037582A1 (en) | 2016-09-21 | 2018-03-29 | Avexxin As | Pharmaceutical composition |
| KR101921727B1 (ko) * | 2016-12-28 | 2018-11-23 | 주식회사 제네웰 | 실리콘 수지 조성물, 이의 제조방법 및 이를 포함하는 흉터 치료제 |
| WO2020141986A1 (en) * | 2018-12-30 | 2020-07-09 | Jamjoom Pharmaceuticals Factory Company Limited | Silicone gel composition containing hyaluronic acid and/or its salt for prevention and repair of skin scars |
| CN113631141A (zh) | 2019-03-01 | 2021-11-09 | 瓦塞尔曼梅迪奇公司 | 新组合物及其用途 |
| CN110200988A (zh) * | 2019-06-17 | 2019-09-06 | 瑞希(重庆)生物科技有限公司 | 一种疤痕修复剂及其制备方法 |
| IT202000001831A1 (it) * | 2020-01-30 | 2021-07-30 | Caprika Srl | Composizione per applicazione rettale a base di sale di acido butirrico per il trattamento delle patologie proctologiche |
| US12396946B1 (en) | 2024-12-30 | 2025-08-26 | Cristcot Llc | Methods of treating gastrointestinal diseases and disorders |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US175414A (en) * | 1876-03-28 | Improvement in compensating-journals for machinery | ||
| JP2622955B2 (ja) * | 1986-07-29 | 1997-06-25 | エイボン プロダクツ インコ−ポレイテツド | 無水化粧品 |
| JPH0618899B2 (ja) * | 1987-06-30 | 1994-03-16 | 品川燃料株式会社 | 抗菌性ゼオライト含有フィルム |
| US5292530A (en) * | 1991-06-02 | 1994-03-08 | Helene Curtis, Inc. | Stable anhydrous topically-active composition and suspending agent therefor |
| JPH049327A (ja) | 1990-04-04 | 1992-01-14 | Kootec Kk | 創傷被覆材 |
| FR2678513B1 (fr) * | 1991-07-03 | 1995-06-30 | Laboratoires Hygiene Dietetique | Pansement cicatrisant. |
| US5380527A (en) * | 1991-08-26 | 1995-01-10 | Dow Corning Corporation | Alkylmethylsiloxane mixtures for skin care |
| US5456906B1 (en) * | 1993-11-17 | 2000-12-05 | Gen Electric | Antiperspirant compositions |
| AU6525296A (en) | 1995-07-19 | 1997-02-18 | Innovative Technologies Limited | Wound treatment composition |
| US5833998A (en) * | 1995-11-06 | 1998-11-10 | The Procter & Gamble Company | Topical compositions for regulating the oily/shiny appearance of skin |
| JPH09194350A (ja) | 1996-01-19 | 1997-07-29 | Morishita Jintan Kk | 創傷被覆材 |
| US5853741A (en) * | 1996-06-28 | 1998-12-29 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Vitamin C delivery system |
| US6231259B1 (en) * | 1996-07-26 | 2001-05-15 | The Gillette Company | Viscous product dispenser with porous dome |
| US5741509A (en) * | 1996-08-26 | 1998-04-21 | Alvin S. Berlat | Silicone wound dressing |
| JPH10265324A (ja) * | 1997-03-25 | 1998-10-06 | Noevir Co Ltd | 油性化粧料 |
| WO1999030629A1 (en) * | 1997-12-17 | 1999-06-24 | Hemodynamics, Inc. | Sealing media for surgery and wound closure |
| CN1343114A (zh) | 1999-02-12 | 2002-04-03 | 宝洁公司 | 皮肤卫生处理组合物 |
| US6183766B1 (en) * | 1999-02-12 | 2001-02-06 | The Procter & Gamble Company | Skin sanitizing compositions |
| GB0007140D0 (en) * | 1999-09-27 | 2000-05-17 | Dow Corning Sa | Scar treatment composition |
| RU2002134482A (ru) * | 2000-05-23 | 2004-03-27 | Унилевер Нв (Nl) | Композиции дезодоранта и/или антиперспиранта |
| PT1409034E (pt) * | 2001-07-24 | 2006-11-30 | Advanced Biotechnologies | Formulação farmacêutica topica |
| JP4071030B2 (ja) * | 2002-04-11 | 2008-04-02 | 花王株式会社 | 表面疎水化吸水性ポリマー粒子 |
| GB0216427D0 (en) * | 2002-07-16 | 2002-08-21 | Advanced Biotechnologies Inter | Wound dressing |
| WO2004039347A1 (ja) * | 2002-11-01 | 2004-05-13 | Kao Corporation | 液状皮膚保護剤組成物 |
| US8486374B2 (en) * | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| US20050142079A1 (en) * | 2003-12-26 | 2005-06-30 | Garrison Mark S. | Oil in silicone emulsion and compositions containing same |
| US20060110415A1 (en) * | 2004-11-22 | 2006-05-25 | Bioderm Research | Topical Delivery System for Cosmetic and Pharmaceutical Agents |
| FR2879931B1 (fr) * | 2004-12-24 | 2007-03-30 | Rhodia Chimie Sa | Materiau silicone pour la liberation d'une molecule active |
| FR2887150B1 (fr) * | 2005-06-17 | 2007-08-03 | Galderma Res & Dev | Composition pharmaceutique comprenant un elastomere organopolysiloxane et un principe actif solubilise |
| JP4993983B2 (ja) | 2005-09-28 | 2012-08-08 | 信越化学工業株式会社 | オルガノポリシロキサン表面処理剤系及び該処理剤系で表面処理された粉体、並びに該粉体を含有する化粧料 |
| EP2407148B1 (en) | 2006-05-11 | 2018-02-21 | Evonik Degussa GmbH | Personal care compositions containing functionalized polymers |
| US20080292560A1 (en) * | 2007-01-12 | 2008-11-27 | Dov Tamarkin | Silicone in glycol pharmaceutical and cosmetic compositions with accommodating agent |
| JP5523114B2 (ja) | 2007-03-08 | 2014-06-18 | モコ セラピューティクス エルエルシー | 傷跡が残ることを防止する及び減少させる被覆製剤 |
| BRPI0817607A2 (pt) * | 2007-09-30 | 2014-10-14 | Valeant Pharmaceuticals Int | Composições a base de gel de silicone para cicatrização de ferimentos e redução de cicatrizes. |
| JP2009132638A (ja) * | 2007-11-29 | 2009-06-18 | Shin Etsu Chem Co Ltd | 化粧料 |
| US7772181B2 (en) * | 2008-10-15 | 2010-08-10 | Danisco Us Inc. | Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors |
| US20100322875A1 (en) * | 2009-06-18 | 2010-12-23 | Advanced Bio-Technologies, Inc. | Silicone scar treatment preparation |
| WO2011006100A1 (en) | 2009-07-09 | 2011-01-13 | Crescendo Therapeutics, Llc | Method of wound healing and scar modulation |
-
2009
- 2009-06-18 US US12/487,489 patent/US20100322875A1/en not_active Abandoned
-
2010
- 2010-06-18 RU RU2011152511/15A patent/RU2530657C2/ru active
- 2010-06-18 LT LTEP10790269.4T patent/LT2442771T/lt unknown
- 2010-06-18 EP EP10790269.4A patent/EP2442771B1/en active Active
- 2010-06-18 SI SI201032005T patent/SI2442771T1/sl unknown
- 2010-06-18 DK DK10790269.4T patent/DK2442771T3/da active
- 2010-06-18 MX MX2011013965A patent/MX2011013965A/es active IP Right Grant
- 2010-06-18 CN CN201080033062.2A patent/CN102802572B/zh active Active
- 2010-06-18 SG SG2011093523A patent/SG176894A1/en unknown
- 2010-06-18 WO PCT/US2010/039181 patent/WO2010148310A1/en not_active Ceased
- 2010-06-18 HU HUE10790269A patent/HUE048612T2/hu unknown
- 2010-06-18 HR HRP20200560TT patent/HRP20200560T1/hr unknown
- 2010-06-18 CA CA2765964A patent/CA2765964C/en active Active
- 2010-06-18 BR BRPI1009689-2A patent/BRPI1009689B1/pt active IP Right Grant
- 2010-06-18 PT PT107902694T patent/PT2442771T/pt unknown
- 2010-06-18 ES ES10790269T patent/ES2781649T3/es active Active
- 2010-06-18 JP JP2012516337A patent/JP5740398B2/ja active Active
- 2010-06-18 PL PL10790269T patent/PL2442771T3/pl unknown
- 2010-06-18 KR KR1020127001182A patent/KR101543060B1/ko active Active
- 2010-06-18 NZ NZ597335A patent/NZ597335A/en unknown
- 2010-06-18 AU AU2010263031A patent/AU2010263031B2/en active Active
-
2011
- 2011-12-18 IL IL217056A patent/IL217056A/en active IP Right Grant
-
2012
- 2012-01-17 ZA ZA2012/00353A patent/ZA201200353B/en unknown
- 2012-07-13 US US13/548,899 patent/US8802133B2/en active Active
-
2014
- 2014-07-02 US US14/322,584 patent/US9339546B2/en active Active
-
2015
- 2015-04-27 JP JP2015090815A patent/JP6016974B2/ja active Active
-
2016
- 2016-04-04 US US15/089,694 patent/US9795706B2/en active Active
-
2020
- 2020-02-26 CY CY20201100176T patent/CY1123227T1/el unknown
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