BRPI1009689B1 - preparação espalhável para auxiliar na cicatrização de feridas e melhorar as características do tecido pós epitelialmente desenvolvido no local da ferida e método para a obtenção de uma preparação espalhável para auxiliar na cicatrização de feridas e no desenvolvimento de tecido de cicatriz - Google Patents

preparação espalhável para auxiliar na cicatrização de feridas e melhorar as características do tecido pós epitelialmente desenvolvido no local da ferida e método para a obtenção de uma preparação espalhável para auxiliar na cicatrização de feridas e no desenvolvimento de tecido de cicatriz Download PDF

Info

Publication number
BRPI1009689B1
BRPI1009689B1 BRPI1009689-2A BRPI1009689A BRPI1009689B1 BR PI1009689 B1 BRPI1009689 B1 BR PI1009689B1 BR PI1009689 A BRPI1009689 A BR PI1009689A BR PI1009689 B1 BRPI1009689 B1 BR PI1009689B1
Authority
BR
Brazil
Prior art keywords
volatile
active component
preparation
siloxane
component
Prior art date
Application number
BRPI1009689-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Guilbaud Paul
Original Assignee
Advanced Bio Tecnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43354570&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1009689(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Advanced Bio Tecnologies Inc filed Critical Advanced Bio Tecnologies Inc
Publication of BRPI1009689A2 publication Critical patent/BRPI1009689A2/pt
Publication of BRPI1009689B1 publication Critical patent/BRPI1009689B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/695Silicon compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/618Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A61K8/585Organosilicon compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/895Polysiloxanes containing silicon bound to unsaturated aliphatic groups, e.g. vinyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0004Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/008Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0095Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/18Antioxidants, e.g. antiradicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/594Mixtures of polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/95Involves in-situ formation or cross-linking of polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Composite Materials (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Silicon Polymers (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
BRPI1009689-2A 2009-06-18 2010-06-18 preparação espalhável para auxiliar na cicatrização de feridas e melhorar as características do tecido pós epitelialmente desenvolvido no local da ferida e método para a obtenção de uma preparação espalhável para auxiliar na cicatrização de feridas e no desenvolvimento de tecido de cicatriz BRPI1009689B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/487,489 US20100322875A1 (en) 2009-06-18 2009-06-18 Silicone scar treatment preparation
PCT/US2010/039181 WO2010148310A1 (en) 2009-06-18 2010-06-18 Silicone scar treatment preparation

Publications (2)

Publication Number Publication Date
BRPI1009689A2 BRPI1009689A2 (pt) 2016-03-15
BRPI1009689B1 true BRPI1009689B1 (pt) 2019-11-12

Family

ID=43354570

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1009689-2A BRPI1009689B1 (pt) 2009-06-18 2010-06-18 preparação espalhável para auxiliar na cicatrização de feridas e melhorar as características do tecido pós epitelialmente desenvolvido no local da ferida e método para a obtenção de uma preparação espalhável para auxiliar na cicatrização de feridas e no desenvolvimento de tecido de cicatriz

Country Status (24)

Country Link
US (4) US20100322875A1 (enExample)
EP (1) EP2442771B1 (enExample)
JP (2) JP5740398B2 (enExample)
KR (1) KR101543060B1 (enExample)
CN (1) CN102802572B (enExample)
AU (1) AU2010263031B2 (enExample)
BR (1) BRPI1009689B1 (enExample)
CA (1) CA2765964C (enExample)
CY (1) CY1123227T1 (enExample)
DK (1) DK2442771T3 (enExample)
ES (1) ES2781649T3 (enExample)
HR (1) HRP20200560T1 (enExample)
HU (1) HUE048612T2 (enExample)
IL (1) IL217056A (enExample)
LT (1) LT2442771T (enExample)
MX (1) MX2011013965A (enExample)
NZ (1) NZ597335A (enExample)
PL (1) PL2442771T3 (enExample)
PT (1) PT2442771T (enExample)
RU (1) RU2530657C2 (enExample)
SG (1) SG176894A1 (enExample)
SI (1) SI2442771T1 (enExample)
WO (1) WO2010148310A1 (enExample)
ZA (1) ZA201200353B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100322875A1 (en) * 2009-06-18 2010-12-23 Advanced Bio-Technologies, Inc. Silicone scar treatment preparation
US9592241B2 (en) 2011-12-27 2017-03-14 Cmpd Licensing, Llc Silicone-based composition for skin treatment
US9499678B2 (en) * 2012-02-24 2016-11-22 Daikin Industries, Ltd. Fluororubber composition
HK1219623A1 (zh) * 2013-05-20 2017-04-13 Zoetis Services Llc 長效的螺環-異惡唑啉抗寄生蟲組合物
US9511034B1 (en) 2013-12-09 2016-12-06 Bio-Silicote, Inc. Method for applying a skin treatment
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
US10653623B2 (en) 2015-03-12 2020-05-19 Cristcot Llc Hydrocortisone acetate suppository formulation for treatment of disease
TWI559923B (en) * 2015-03-16 2016-12-01 Amed Co Ltd A composition of silicone gel for wound dressing
CN104814886A (zh) * 2015-04-10 2015-08-05 浙江省诸暨市珠力神医用品有限公司 一种硅凝胶组合物
CN104784066A (zh) * 2015-04-10 2015-07-22 浙江省诸暨市珠力神医用品有限公司 一种抗紫外线的硅凝胶组合物
CA3037582A1 (en) 2016-09-21 2018-03-29 Avexxin As Pharmaceutical composition
GB201616088D0 (en) * 2016-09-21 2016-11-02 Avexxin As Pharmaceutical composition
KR101921727B1 (ko) * 2016-12-28 2018-11-23 주식회사 제네웰 실리콘 수지 조성물, 이의 제조방법 및 이를 포함하는 흉터 치료제
WO2020141986A1 (en) * 2018-12-30 2020-07-09 Jamjoom Pharmaceuticals Factory Company Limited Silicone gel composition containing hyaluronic acid and/or its salt for prevention and repair of skin scars
KR20210136049A (ko) 2019-03-01 2021-11-16 와서만 메딕 에이비 신규 조성물 및 이의 용도
CN110200988A (zh) * 2019-06-17 2019-09-06 瑞希(重庆)生物科技有限公司 一种疤痕修复剂及其制备方法
IT202000001831A1 (it) * 2020-01-30 2021-07-30 Caprika Srl Composizione per applicazione rettale a base di sale di acido butirrico per il trattamento delle patologie proctologiche
US12396946B1 (en) 2024-12-30 2025-08-26 Cristcot Llc Methods of treating gastrointestinal diseases and disorders

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US175414A (en) * 1876-03-28 Improvement in compensating-journals for machinery
JP2622955B2 (ja) * 1986-07-29 1997-06-25 エイボン プロダクツ インコ−ポレイテツド 無水化粧品
JPH0618899B2 (ja) * 1987-06-30 1994-03-16 品川燃料株式会社 抗菌性ゼオライト含有フィルム
US5292530A (en) * 1991-06-02 1994-03-08 Helene Curtis, Inc. Stable anhydrous topically-active composition and suspending agent therefor
JPH049327A (ja) 1990-04-04 1992-01-14 Kootec Kk 創傷被覆材
FR2678513B1 (fr) * 1991-07-03 1995-06-30 Laboratoires Hygiene Dietetique Pansement cicatrisant.
US5380527A (en) * 1991-08-26 1995-01-10 Dow Corning Corporation Alkylmethylsiloxane mixtures for skin care
US5456906B1 (en) * 1993-11-17 2000-12-05 Gen Electric Antiperspirant compositions
WO1997003710A1 (en) 1995-07-19 1997-02-06 Innovative Technologies Limited Wound treatment composition
US5833998A (en) * 1995-11-06 1998-11-10 The Procter & Gamble Company Topical compositions for regulating the oily/shiny appearance of skin
JPH09194350A (ja) 1996-01-19 1997-07-29 Morishita Jintan Kk 創傷被覆材
US5750123A (en) * 1996-06-28 1998-05-12 Chesebrough-Pond's Co., Division Of Conopco, Inc. Vitamin C delivery system
US6231259B1 (en) * 1996-07-26 2001-05-15 The Gillette Company Viscous product dispenser with porous dome
US5741509A (en) * 1996-08-26 1998-04-21 Alvin S. Berlat Silicone wound dressing
JPH10265324A (ja) * 1997-03-25 1998-10-06 Noevir Co Ltd 油性化粧料
AU1923199A (en) * 1997-12-17 1999-07-05 Hemodynamics, Inc. Sealing media for surgery and wound closure
JP2002536397A (ja) 1999-02-12 2002-10-29 ザ、プロクター、エンド、ギャンブル、カンパニー 皮膚消毒剤組成物
US6183766B1 (en) * 1999-02-12 2001-02-06 The Procter & Gamble Company Skin sanitizing compositions
GB0007140D0 (en) * 1999-09-27 2000-05-17 Dow Corning Sa Scar treatment composition
MXPA02011440A (es) * 2000-05-23 2003-04-25 Unilever Nv Composiciones desodorantes y/o antitranspirantes.
DK1409034T3 (da) * 2001-07-24 2006-10-30 Advanced Biotechnologies Topisk farmaceutisk formulering
JP4071030B2 (ja) * 2002-04-11 2008-04-02 花王株式会社 表面疎水化吸水性ポリマー粒子
GB0216427D0 (en) * 2002-07-16 2002-08-21 Advanced Biotechnologies Inter Wound dressing
WO2004039347A1 (ja) * 2002-11-01 2004-05-13 Kao Corporation 液状皮膚保護剤組成物
US8486374B2 (en) * 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US20050142079A1 (en) * 2003-12-26 2005-06-30 Garrison Mark S. Oil in silicone emulsion and compositions containing same
US20060110415A1 (en) * 2004-11-22 2006-05-25 Bioderm Research Topical Delivery System for Cosmetic and Pharmaceutical Agents
FR2879931B1 (fr) * 2004-12-24 2007-03-30 Rhodia Chimie Sa Materiau silicone pour la liberation d'une molecule active
FR2887150B1 (fr) * 2005-06-17 2007-08-03 Galderma Res & Dev Composition pharmaceutique comprenant un elastomere organopolysiloxane et un principe actif solubilise
JP4993983B2 (ja) * 2005-09-28 2012-08-08 信越化学工業株式会社 オルガノポリシロキサン表面処理剤系及び該処理剤系で表面処理された粉体、並びに該粉体を含有する化粧料
EP2407148B1 (en) * 2006-05-11 2018-02-21 Evonik Degussa GmbH Personal care compositions containing functionalized polymers
US20080292560A1 (en) * 2007-01-12 2008-11-27 Dov Tamarkin Silicone in glycol pharmaceutical and cosmetic compositions with accommodating agent
MX2009009557A (es) 2007-03-08 2010-08-10 Crescendo Therapeutics Llc Formulaciones de aposito para prevenir o reducir la cicatrizacion.
PT2211919E (pt) * 2007-09-30 2011-12-05 Meda Ab Composições à base de gel de silicone para cicatrização de ferimentos e redução de cicatriz
JP2009132638A (ja) * 2007-11-29 2009-06-18 Shin Etsu Chem Co Ltd 化粧料
US7772181B2 (en) * 2008-10-15 2010-08-10 Danisco Us Inc. Personal care compositions comprising modified variant Bowman Birk Protease Inhibitors
US20100322875A1 (en) * 2009-06-18 2010-12-23 Advanced Bio-Technologies, Inc. Silicone scar treatment preparation
AU2010271205A1 (en) 2009-07-09 2012-02-09 Moko Therapeutics Llc. Method of wound healing and scar modulation

Also Published As

Publication number Publication date
JP2015166362A (ja) 2015-09-24
EP2442771A1 (en) 2012-04-25
JP2012530719A (ja) 2012-12-06
HRP20200560T1 (hr) 2020-07-10
ZA201200353B (en) 2013-07-31
BRPI1009689A2 (pt) 2016-03-15
ES2781649T3 (es) 2020-09-04
KR20120062678A (ko) 2012-06-14
IL217056A (en) 2013-12-31
AU2010263031B2 (en) 2014-05-01
MX2011013965A (es) 2012-04-19
CA2765964C (en) 2017-05-23
US20130183256A1 (en) 2013-07-18
US20160213810A1 (en) 2016-07-28
PT2442771T (pt) 2020-04-07
AU2010263031A1 (en) 2012-01-19
US9795706B2 (en) 2017-10-24
JP6016974B2 (ja) 2016-10-26
EP2442771B1 (en) 2020-02-05
PL2442771T3 (pl) 2020-07-13
US20100322875A1 (en) 2010-12-23
US9339546B2 (en) 2016-05-17
NZ597335A (en) 2014-02-28
HUE048612T2 (hu) 2020-08-28
EP2442771A4 (en) 2013-01-09
US20140314695A1 (en) 2014-10-23
KR101543060B1 (ko) 2015-08-07
SG176894A1 (en) 2012-01-30
US8802133B2 (en) 2014-08-12
SI2442771T1 (sl) 2020-07-31
CA2765964A1 (en) 2010-12-23
WO2010148310A1 (en) 2010-12-23
CY1123227T1 (el) 2021-10-29
IL217056A0 (en) 2012-02-29
LT2442771T (lt) 2020-05-25
CN102802572B (zh) 2015-12-02
DK2442771T3 (da) 2020-04-27
RU2530657C2 (ru) 2014-10-10
JP5740398B2 (ja) 2015-06-24
RU2011152511A (ru) 2013-07-27
CN102802572A (zh) 2012-11-28

Similar Documents

Publication Publication Date Title
BRPI1009689B1 (pt) preparação espalhável para auxiliar na cicatrização de feridas e melhorar as características do tecido pós epitelialmente desenvolvido no local da ferida e método para a obtenção de uma preparação espalhável para auxiliar na cicatrização de feridas e no desenvolvimento de tecido de cicatriz
Sequeira Diseases of the Skin
ES2675228T3 (es) Preparaciones tópicas de vasoconstrictores y métodos para proteger a las células durante la quimioterapia y radioterapia del cáncer
BRPI0111142B1 (pt) Use of derivatives of biguanide or of its pharmaceutically acceptable salts thereof for manufacture of a medicinal product having a healing effect
PT95211B (pt) Processo para a preparacao de composicoes para uso topico contendo acidos desoxi-ribonucleicos despolimerizados para reduzir defeitos nao visiveis da epider me da face e de algumas areas da pele do corpo
PT1515734E (pt) Preparação baseada em mel para cuidados de pele
ES2827953T3 (es) Medicamento externo para neurofibroma plexiforme difuso
ES2730885T3 (es) Composición para cubrir y proteger cicatrices
PT988033E (pt) Utilizacao de alcool diclorobenzilico para preparar uma preparacao para o tratamento topico de inflamacao
TW200404567A (en) Stabilised topical formulations containing ketoprofen
CN116270311A (zh) 具有液晶结构的防晒保湿修护薄膜组合物
Sruthi et al. Efficacy of Topical Anaesthesia-Lignocaine vs. Emla in the Management of Needle Prick Pain in Children
HK1164105B (en) Silicone scar treatment preparation
HK1164105A (en) Silicone scar treatment preparation
US20130266525A1 (en) High protection uva/uvb composition and topical cosmetic composition
BR102017011377B1 (pt) Composição e formulação tópica anestésica de (2e,8e)- n-isobutildeca- 2,8-dien-6-inamida e seu uso
BR102021010040A2 (pt) Protetor solar
ES2660978T3 (es) Método y composiciones para el tratamiento de la psoriasis
TW201116274A (en) Pharmaceutical composition
Montaldo et al. Natural antioxidants effect on monocyte THP-1 interleukin 1β and nitrite production
JP2025028638A (ja) 乾皮症治療用の油中水型乳化組成物である外用塗布剤
BR102021004476A2 (pt) Formulação tópica em gel de poloxamer adicionado de hesperidina metil chalcona para tratamento de queimaduras térmicas
Shenoi et al. Absence of photosensitivity in Parthenium dermatitis clinically resembling chronic actinic dermatitis.
PT1700597E (pt) Composição farmacêutica contendo em associação ubidecarenona, dexpantenol e cloro-hexidina ou seu sal farmaceuticamente aceitável para aplicação cutânea

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/06/2010, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/06/2010, OBSERVADAS AS CONDICOES LEGAIS