JP2012518598A5 - - Google Patents
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- Publication number
- JP2012518598A5 JP2012518598A5 JP2011535742A JP2011535742A JP2012518598A5 JP 2012518598 A5 JP2012518598 A5 JP 2012518598A5 JP 2011535742 A JP2011535742 A JP 2011535742A JP 2011535742 A JP2011535742 A JP 2011535742A JP 2012518598 A5 JP2012518598 A5 JP 2012518598A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- pyrimido
- anticancer
- alkyl group
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011535742A JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009042873 | 2009-02-25 | ||
| JP2009042873 | 2009-02-25 | ||
| PCT/JP2010/052910 WO2010098367A1 (en) | 2009-02-25 | 2010-02-18 | Pyrimidopyrimidoindazole derivative |
| JP2011535742A JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012518598A JP2012518598A (ja) | 2012-08-16 |
| JP2012518598A5 true JP2012518598A5 (https=) | 2013-04-04 |
Family
ID=42665571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011535742A Pending JP2012518598A (ja) | 2009-02-25 | 2010-02-18 | ピリミドピリミドインダゾール誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8288396B2 (https=) |
| EP (1) | EP2401281A4 (https=) |
| JP (1) | JP2012518598A (https=) |
| AU (1) | AU2010218781A1 (https=) |
| CA (1) | CA2750716A1 (https=) |
| WO (1) | WO2010098367A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2621857T3 (es) | 2010-11-16 | 2017-07-05 | Array Biopharma, Inc. | Combinación de inhibidores de la cinasa 1 de punto de control e inhibidores de la cinasa WEE1 |
| CR20190436A (es) | 2012-10-02 | 2019-10-29 | Bayer Cropscience Ag | COMPUESTOS HETEROCICLICOS COMO PLAGUICIDAS (Divisional 2015-0182) |
| FR3030513B1 (fr) * | 2014-12-19 | 2016-12-23 | Oreal | Derives de benzoxazine cationiques et utilisation en coloration capillaire. |
| DE102015012050A1 (de) * | 2015-09-15 | 2017-03-16 | Merck Patent Gmbh | Verbindungen als ASIC-Inhibitoren und deren Verwendungen |
| US20200108074A1 (en) | 2017-03-31 | 2020-04-09 | Seattle Genetics, Inc. | Combinations of chk1- and wee1- inhibitors |
| AR111419A1 (es) * | 2017-04-27 | 2019-07-10 | Novartis Ag | Compuestos fusionados de indazol piridona como antivirales |
| JP2021507906A (ja) | 2017-12-20 | 2021-02-25 | ノバルティス アーゲー | 抗ウイルス剤としての融合三環式ピラゾロ−ジヒドロピラジニル−ピリドン化合物 |
| CN109912606B (zh) * | 2019-04-16 | 2021-05-04 | 新乡医学院 | 一种嘧啶并吲唑类化合物的合成方法 |
| KR20220042127A (ko) | 2019-06-28 | 2022-04-04 | 상하이 파마슈티컬스 홀딩 컴퍼니 리미티드 | 피라졸로피리미딘 화합물, 그의 제조 방법 및 그의 응용 |
| CN112142748B (zh) | 2019-06-28 | 2023-07-04 | 上海医药集团股份有限公司 | 一种吡唑酮并嘧啶类化合物、其制备方法及应用 |
| US12551584B1 (en) | 2020-12-07 | 2026-02-17 | Actinium Pharmaceuticals, Inc. | Lewis Y radioimmunotherapy for the treatment of cancer |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| US5223608A (en) | 1987-08-28 | 1993-06-29 | Eli Lilly And Company | Process for and intermediates of 2',2'-difluoronucleosides |
| SK283693B6 (sk) | 1990-09-28 | 2003-12-02 | Smithkline Beecham Corporation | Spôsob prípravy kamptotecínu alebo jeho farmaceuticky prijateľnej soli |
| US5243050A (en) | 1990-12-20 | 1993-09-07 | North Carolina State University | Alkylpyridone DE ring intermediates useful for the manufacture of camptothecin and camptothecin analogs |
| US5200524A (en) | 1990-12-20 | 1993-04-06 | North Carolina State University | Camptothecin intermediates and method of making same |
| US5247089A (en) | 1990-12-20 | 1993-09-21 | North Carolina State University | Method of making intermediates useful for the manufacture of camptothecin and camptothecin analogs |
| US5191082A (en) | 1990-12-20 | 1993-03-02 | North Carolina State University | Camptothecin intermediate and method of making camptothecin intermediates |
| US5162532A (en) | 1990-12-20 | 1992-11-10 | North Carolina State University | Intermediates and method of making camptothecin and camptothecin analogs |
| BR9207175A (pt) | 1992-10-28 | 1995-12-12 | Genentech Inc | Composição contendo antagonista de fator de crescimento de célula endotelial vascular sequência aminoácida de anticorpo monoclonal polipeptídeo e método de tratamento de tumor em mamífero |
| JP3025602B2 (ja) | 1993-05-21 | 2000-03-27 | デビオファーム エス．アー． | 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法 |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| AU6267896A (en) | 1995-06-07 | 1996-12-30 | Imclone Systems Incorporated | Antibody and antibody fragments for inhibiting the growth oftumors |
| JP3154399B2 (ja) | 1996-07-04 | 2001-04-09 | デビオファーム エス．アー． | 白金化合物の製造方法 |
| AU763839B2 (en) * | 1998-05-26 | 2003-07-31 | Warner-Lambert Company | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
| US20040044012A1 (en) | 1998-05-26 | 2004-03-04 | Dobrusin Ellen Myra | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
| EP1501831A1 (en) * | 2002-04-26 | 2005-02-02 | Warner-Lambert Company Llc | Inhibitors of checkpoint kinases (wee1 and chk1) |
| US7094798B1 (en) * | 2002-04-26 | 2006-08-22 | Pfizer Inc | Inhibitors of checkpoint kinases (Wee1 and Chk1) |
| US20050250836A1 (en) * | 2004-05-03 | 2005-11-10 | Pfizer Inc | Inhibitors of checkpoint kinases (Wee1 and Chk1) |
| AR060635A1 (es) | 2006-04-27 | 2008-07-02 | Banyu Pharma Co Ltd | Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer |
| ES2608940T3 (es) * | 2007-06-15 | 2017-04-17 | Msd K.K. | Derivado de bicicloanilina |
-
2010
- 2010-02-18 EP EP10746246A patent/EP2401281A4/en not_active Withdrawn
- 2010-02-18 AU AU2010218781A patent/AU2010218781A1/en not_active Abandoned
- 2010-02-18 JP JP2011535742A patent/JP2012518598A/ja active Pending
- 2010-02-18 CA CA2750716A patent/CA2750716A1/en not_active Abandoned
- 2010-02-18 US US13/202,773 patent/US8288396B2/en not_active Expired - Fee Related
- 2010-02-18 WO PCT/JP2010/052910 patent/WO2010098367A1/en not_active Ceased
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