JP2012517225A5 - - Google Patents

Info

Publication number

JP2012517225A5

JP2012517225A5 JP2011549110A JP2011549110A JP2012517225A5 JP 2012517225 A5 JP2012517225 A5 JP 2012517225A5 JP 2011549110 A JP2011549110 A JP 2011549110A JP 2011549110 A JP2011549110 A JP 2011549110A JP 2012517225 A5 JP2012517225 A5 JP 2012517225A5

Authority

JP

Japan

Prior art keywords

seq

protein

sequence number

bacteriophage

acid sequence

Prior art date

2010-02-05

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 108090000623 proteins and genes Proteins 0.000 claims 36
• 102000004169 proteins and genes Human genes 0.000 claims 36
• 241001515965 unidentified phage Species 0.000 claims 36
• 239000008194 pharmaceutical composition Substances 0.000 claims 19
• 230000000845 anti-microbial effect Effects 0.000 claims 18
• 239000012634 fragment Substances 0.000 claims 18
• 150000007523 nucleic acids Chemical group 0.000 claims 15
• 125000003275 alpha amino acid group Chemical group 0.000 claims 14
• 230000000844 anti-bacterial effect Effects 0.000 claims 14
• 241000894006 Bacteria Species 0.000 claims 12
• 241000588626 Acinetobacter baumannii Species 0.000 claims 11
• 241000194032 Enterococcus faecalis Species 0.000 claims 11
• 229940032049 enterococcus faecalis Drugs 0.000 claims 11
• 241000191967 Staphylococcus aureus Species 0.000 claims 10
• 241000194031 Enterococcus faecium Species 0.000 claims 9
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 9
• 241000589517 Pseudomonas aeruginosa Species 0.000 claims 8
• 239000013543 active substance Substances 0.000 claims 8
• 208000015181 infectious disease Diseases 0.000 claims 6
• 108020004707 nucleic acids Proteins 0.000 claims 6
• 102000039446 nucleic acids Human genes 0.000 claims 6
• 208000035143 Bacterial infection Diseases 0.000 claims 4
• 208000022362 bacterial infectious disease Diseases 0.000 claims 4
• 229920001184 polypeptide Polymers 0.000 claims 4
• 102000004196 processed proteins & peptides Human genes 0.000 claims 4
• 108090000765 processed proteins & peptides Proteins 0.000 claims 4
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
• 101000870242 Bacillus phage Nf Tail knob protein gp9 Proteins 0.000 claims 3
• 241000124008 Mammalia Species 0.000 claims 3
• 101710204224 Tape measure protein Proteins 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• 239000003112 inhibitor Substances 0.000 claims 3
• 238000000034 method Methods 0.000 claims 3
• 210000001519 tissue Anatomy 0.000 claims 3
• 241000194033 Enterococcus Species 0.000 claims 2
• KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 2
• 239000004472 Lysine Substances 0.000 claims 2
• 239000003937 drug carrier Substances 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 239000007787 solid Substances 0.000 claims 2
• 206010011409 Cross infection Diseases 0.000 claims 1
• 208000008960 Diabetic foot Diseases 0.000 claims 1
• 239000004599 antimicrobial Substances 0.000 claims 1
• 230000001580 bacterial effect Effects 0.000 claims 1
• 230000004071 biological effect Effects 0.000 claims 1
• 238000001574 biopsy Methods 0.000 claims 1
• 210000004369 blood Anatomy 0.000 claims 1
• 239000008280 blood Substances 0.000 claims 1
• 210000001124 body fluid Anatomy 0.000 claims 1
• 239000010839 body fluid Substances 0.000 claims 1
• 230000005757 colony formation Effects 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 231100000676 disease causative agent Toxicity 0.000 claims 1
• 238000004090 dissolution Methods 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 230000000694 effects Effects 0.000 claims 1
• 239000000203 mixture Substances 0.000 claims 1
• 238000012544 monitoring process Methods 0.000 claims 1
• 210000004400 mucous membrane Anatomy 0.000 claims 1
• 239000002773 nucleotide Substances 0.000 claims 1
• 125000003729 nucleotide group Chemical group 0.000 claims 1
• 239000000825 pharmaceutical preparation Substances 0.000 claims 1
• 229940127557 pharmaceutical product Drugs 0.000 claims 1
• 206010040872 skin infection Diseases 0.000 claims 1
• 241000894007 species Species 0.000 claims 1