JP2012516894A5 - - Google Patents
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- Publication number
- JP2012516894A5 JP2012516894A5 JP2011549242A JP2011549242A JP2012516894A5 JP 2012516894 A5 JP2012516894 A5 JP 2012516894A5 JP 2011549242 A JP2011549242 A JP 2011549242A JP 2011549242 A JP2011549242 A JP 2011549242A JP 2012516894 A5 JP2012516894 A5 JP 2012516894A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- methyl
- somechi
- pyridin
- fluorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- -1 pyridin-yl Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14940209P | 2009-02-03 | 2009-02-03 | |
| US61/149,402 | 2009-02-03 | ||
| PCT/US2010/023122 WO2010091131A1 (en) | 2009-02-03 | 2010-02-03 | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012516894A JP2012516894A (ja) | 2012-07-26 |
| JP2012516894A5 true JP2012516894A5 (enExample) | 2013-03-07 |
| JP5584705B2 JP5584705B2 (ja) | 2014-09-03 |
Family
ID=42289775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011549242A Active JP5584705B2 (ja) | 2009-02-03 | 2010-02-03 | Ｒ）−３−（４−（２−（２−メチルテトラゾール−５−イル）ピリジン−５−イル）−３−フルオロフェニル）−５−ヒドロキシメチルオキサゾリジン−２−オンリン酸二水素の結晶形 |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US8426389B2 (enExample) |
| EP (1) | EP2393808B1 (enExample) |
| JP (1) | JP5584705B2 (enExample) |
| KR (3) | KR101739923B1 (enExample) |
| CN (2) | CN102439006A (enExample) |
| AP (1) | AP2987A (enExample) |
| AU (1) | AU2010210627B2 (enExample) |
| BR (1) | BRPI1008829A2 (enExample) |
| CA (1) | CA2751392C (enExample) |
| CL (1) | CL2011001855A1 (enExample) |
| CO (1) | CO6620071A2 (enExample) |
| CR (1) | CR20110464A (enExample) |
| CU (1) | CU24089B1 (enExample) |
| DO (1) | DOP2011000251A (enExample) |
| EC (1) | ECSP11011285A (enExample) |
| ES (1) | ES2734724T3 (enExample) |
| IL (1) | IL214401B (enExample) |
| MA (1) | MA33092B1 (enExample) |
| MX (3) | MX2011008093A (enExample) |
| MY (1) | MY156354A (enExample) |
| NZ (3) | NZ620458A (enExample) |
| PE (1) | PE20120585A1 (enExample) |
| PH (1) | PH12014500092A1 (enExample) |
| RU (2) | RU2655928C1 (enExample) |
| SG (2) | SG173497A1 (enExample) |
| TN (1) | TN2011000381A1 (enExample) |
| UA (1) | UA114068C2 (enExample) |
| WO (1) | WO2010091131A1 (enExample) |
| ZA (2) | ZA201106412B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| MX2011003820A (es) | 2008-10-10 | 2011-06-16 | Trius Therapeutics | Metodos para preparar oxazolidinonas y composiciones que las contienen. |
| SG173497A1 (en) | 2009-02-03 | 2011-09-29 | Trius Therapeutics | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
| US8580767B2 (en) * | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
| WO2013059610A1 (en) | 2011-10-20 | 2013-04-25 | Trius Therapeutics, Inc. | Therapeutic combination of daptomycin and protein synthesis inhibitor antibiotic, and methods of use |
| WO2015054246A1 (en) * | 2013-10-07 | 2015-04-16 | Trius Therapeutics, Inc. | Methods of treating subjects with renal impairment using tedizolid |
| WO2015158202A1 (zh) * | 2014-04-18 | 2015-10-22 | 杭州普晒医药科技有限公司 | 一种噁唑烷酮类抗生素的晶型及制备方法、组合物和用途 |
| WO2016009401A2 (en) * | 2014-07-18 | 2016-01-21 | Dr. Reddy's Laboratories Limited | Preparation of tedizolid phosphate |
| CN104327119A (zh) * | 2014-10-17 | 2015-02-04 | 苏州明锐医药科技有限公司 | 磷酸泰地唑胺的制备方法 |
| WO2016063246A1 (en) * | 2014-10-22 | 2016-04-28 | Sun Pharmaceutical Industries Limited | Crystalline form r of tedizolid phosphate |
| WO2016088102A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
| WO2016088100A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
| WO2016088101A1 (en) * | 2014-12-05 | 2016-06-09 | Sun Pharmaceutical Industries Limited | Processes for the preparation of tedizolid phosphate and its intermediates |
| CZ306245B6 (cs) * | 2014-12-11 | 2016-10-26 | Univerzita Karlova v Praze Farmaceutická fakulta v Hradci Králové | Substituovaný fenyltetrazol, jeho použití a farmaceutický přípravek ho obsahující |
| CN104558034A (zh) * | 2015-01-21 | 2015-04-29 | 齐鲁制药有限公司 | 磷酸特地唑胺二钠盐的新晶型及其制备方法 |
| CN105837634B (zh) * | 2015-01-30 | 2020-09-04 | 上海创诺制药有限公司 | 一种泰地唑胺磷酸酯结晶体及其制备方法 |
| CN104592218B (zh) * | 2015-02-13 | 2015-11-04 | 江苏欧信医药化工有限公司 | 一种泰地唑胺的合成方法 |
| CN106146485B (zh) * | 2015-04-01 | 2021-04-30 | 上海迪赛诺化学制药有限公司 | 一种制备泰地唑胺的方法及其得到的泰地唑胺结晶体 |
| CN106146558A (zh) * | 2015-04-10 | 2016-11-23 | 博瑞生物医药（苏州）股份有限公司 | 新的噁唑烷酮类化合物及其制备方法 |
| CN106317114B (zh) * | 2015-07-02 | 2018-11-20 | 南京优科制药有限公司 | 一种磷酸特地唑胺的制备方法 |
| CN105085570B (zh) * | 2015-09-12 | 2017-11-28 | 山东罗欣药业集团股份有限公司 | 一种磷酸特地唑胺化合物及其制备方法 |
| CN105287407B (zh) * | 2015-11-24 | 2018-09-21 | 南京正大天晴制药有限公司 | 一种注射用磷酸特地唑胺 |
| CN107121503B (zh) * | 2017-03-14 | 2020-04-28 | 南京优科制药有限公司 | 一种磷酸特地唑胺及其有关物质的分析方法 |
| CN108948079A (zh) * | 2017-05-17 | 2018-12-07 | 上海奥博生物医药技术有限公司 | 一种特地唑胺二铵盐及晶型与其制备方法 |
| EP3723758A4 (en) * | 2017-12-13 | 2021-06-23 | Merck Sharp & Dohme Corp. | PHARMACEUTICAL COMPOSITIONS OF TEDICOLIDE PHOSPHATE |
| KR102777328B1 (ko) | 2018-07-25 | 2025-03-10 | 자이두스 라이프사이언시즈 리미티드 | 포유류 감염 치료를 위한 신규 화합물 |
| WO2021258013A1 (en) | 2020-06-18 | 2021-12-23 | Akagera Medicines, Inc. | Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof |
| CN112957332B (zh) * | 2021-02-04 | 2023-04-25 | 海南通用康力制药有限公司 | 注射用磷酸特地唑胺及其质量标准 |
| CN112957333B (zh) * | 2021-02-05 | 2022-11-22 | 海南通用康力制药有限公司 | 注射用磷酸特地唑胺及其制备方法 |
| CN113197874B (zh) * | 2021-04-28 | 2023-05-26 | 北京福元医药股份有限公司 | 一种磷酸特地唑胺口服固体制剂 |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU80081A1 (fr) * | 1977-08-26 | 1979-05-15 | Delalande Sa | Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique |
| US4128654A (en) * | 1978-02-10 | 1978-12-05 | E. I. Du Pont De Nemours And Company | 5-Halomethyl-3-phenyl-2-oxazolidinones |
| US4340606A (en) * | 1980-10-23 | 1982-07-20 | E. I. Du Pont De Nemours And Company | 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents |
| FR2500450A1 (fr) * | 1981-02-25 | 1982-08-27 | Delalande Sa | Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique |
| US4461773A (en) * | 1982-09-15 | 1984-07-24 | E. I. Dupont De Nemours And Company | P-Oxooxazolidinylbenzene compounds as antibacterial agents |
| CA1320730C (en) | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
| US4948801A (en) | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5254577A (en) | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5144911A (en) * | 1990-11-28 | 1992-09-08 | Moore Cheri L | Component bed system for a pet |
| ATE146783T1 (de) | 1991-11-01 | 1997-01-15 | Upjohn Co | Substituierte aryl- und heteroaryl- phenyloxazolidinone |
| SK283420B6 (sk) | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| PL175782B1 (pl) * | 1992-12-08 | 1999-02-26 | Upjohn Co | Nowe podstawione troponem pochodne fenylooksazolidynonowe |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| WO1995014684A1 (en) * | 1993-11-22 | 1995-06-01 | The Upjohn Company | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| GB9702213D0 (en) * | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
| US6413981B1 (en) | 1999-08-12 | 2002-07-02 | Ortho-Mcneil Pharamceutical, Inc. | Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| JP2003535860A (ja) | 2000-06-05 | 2003-12-02 | ドン・ア・ファーム・カンパニー・リミテッド | 新規なオキサゾリジノン誘導体及びその製造方法 |
| US20020115669A1 (en) * | 2000-08-31 | 2002-08-22 | Wiedeman Paul E. | Oxazolidinone chemotherapeutic agents |
| YU52403A (sh) | 2000-12-26 | 2006-03-03 | Dr.Reddy's Research Foundation | Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže |
| US20050032861A1 (en) | 2001-04-07 | 2005-02-10 | Betts Michael John | Oxazolidines containing a sulfonimid group as antibiotics |
| US6623140B2 (en) | 2001-04-13 | 2003-09-23 | Scott R. Watterson | Illumination device having multiple light sources |
| US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
| CA2459766A1 (en) | 2001-09-11 | 2003-03-20 | Astrazeneca Ab | Oxazolidinone and/or isoxazoline as antibacterial agents |
| DE60210654T2 (de) | 2001-10-25 | 2007-01-25 | Astrazeneca Ab | Aryl substituierte oxazolidinone mit antibacterieller activität |
| NZ515881A (en) | 2001-12-03 | 2004-09-24 | New Zealand Dairy Board | Cheese flavour ingredient and method of its production |
| AR038536A1 (es) * | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| RU2004129278A (ru) | 2002-02-28 | 2005-06-10 | Астразенека Аб (Se) | Химические соединения |
| US7473699B2 (en) | 2002-02-28 | 2009-01-06 | Astrazeneca Ab | 3-cyclyl-5-(nitrogen-containing 5-membered ring)methyl-oxazolidinone derivatives and their use as antibacterial agents |
| MXPA05005651A (es) * | 2002-11-28 | 2005-07-27 | Astrazeneca Ab | Derivados de oxazolidinona y/o isoxazolina como agentes antibacterianos. |
| EP1581524A2 (en) | 2002-11-28 | 2005-10-05 | AstraZeneca AB | Oxazolidinones as antibacterial agents |
| US7202257B2 (en) * | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| US7144911B2 (en) * | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| TW200500360A (en) * | 2003-03-01 | 2005-01-01 | Astrazeneca Ab | Hydroxymethyl compounds |
| GB0306358D0 (en) | 2003-03-20 | 2003-04-23 | Astrazeneca Ab | Chemical compounds |
| AU2004256085B2 (en) * | 2003-07-02 | 2007-12-06 | Kyorin, Pharmaceutical Co., Ltd. | Cyclopropyl Group Substituted Oxazolydinone Antibiotics and Derivatives Thereof |
| ATE471937T1 (de) | 2003-07-02 | 2010-07-15 | Merck Sharp & Dohme | Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon |
| NZ529860A (en) | 2003-11-28 | 2006-10-27 | Ovita Ltd | Muscle growth regulator mighty and use in promoting muscle mass and treating muscle wasting diseases |
| WO2005051933A1 (en) | 2003-11-28 | 2005-06-09 | Ranbaxy Laboratories Limited | An improved process for the synthesis of 4-(4-benzyloxy-carbonylamino-2-fluorophenyl)-piperazine-1-carboxylic acid tert-butyl ester, a key intermediate for oxazolidinone antimicrobials and compounds prepared thereby |
| TW200526649A (en) * | 2003-12-17 | 2005-08-16 | Rib X Pharmaceuticals Inc | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
| KR100854211B1 (ko) * | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| US20070191336A1 (en) * | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
| GB0411596D0 (en) | 2004-05-25 | 2004-06-30 | Astrazeneca Ab | Chemical process |
| AU2005247671A1 (en) * | 2004-05-25 | 2005-12-08 | Astrazeneca Ab | 3- (4- (2-dihydroisoxazol-3-ylpyridin-5-yl) phenyl) -5-triazol-1-ylmethyloxazolidin-2-one derivaives as MAO inhibitors for the treatment of bacterial infections |
| US20080064689A1 (en) * | 2004-05-25 | 2008-03-13 | Astrazeneca Ab | 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents |
| JP2008500318A (ja) * | 2004-05-25 | 2008-01-10 | アストラゼネカ アクチボラグ | 抗菌剤としての３−｛４−（ピリジン−３−イル）フェニル｝−５−（１ｈ−１，２，３−トリアゾール−１−イルメチル）−１，３−オキサゾリジン−２−オン |
| JP2008500317A (ja) * | 2004-05-25 | 2008-01-10 | アストラゼネカ アクチボラグ | 抗菌剤としての３−’４−｛６−置換アルカノイル）ピリジン−３−イル｝−３−フェニル−５−（１ｈ−１，２，３−トリアゾール−１−イルメチル）−１，３−オキサゾリジン−２−オン |
| EP1799677A1 (en) | 2004-10-08 | 2007-06-27 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
| WO2007023507A2 (en) | 2005-06-20 | 2007-03-01 | Wockhardt Limited | Oxazolidinones bearing antimicrobial activity composition and methods of preparation |
| WO2007138381A2 (en) | 2005-10-14 | 2007-12-06 | Targanta Therapeutics Inc. | Phosphonated oxazolidinones and uses thereof for the prevention and treatment of bone and joint infections |
| WO2009020616A1 (en) * | 2007-08-06 | 2009-02-12 | Micurx Pharmaceuticals, Inc. | Antimicrobial ortho-fluorophenyl oxazolidinones for treatment of bacterial infections |
| CN101220001A (zh) * | 2008-01-25 | 2008-07-16 | 浙江博泰化工有限公司 | 一种利奈唑酮的合成方法 |
| MX2011003820A (es) | 2008-10-10 | 2011-06-16 | Trius Therapeutics | Metodos para preparar oxazolidinonas y composiciones que las contienen. |
| SG173497A1 (en) | 2009-02-03 | 2011-09-29 | Trius Therapeutics | Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
| US8580767B2 (en) | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
-
2010
- 2010-02-03 SG SG2011055456A patent/SG173497A1/en unknown
- 2010-02-03 WO PCT/US2010/023122 patent/WO2010091131A1/en not_active Ceased
- 2010-02-03 KR KR1020117020614A patent/KR101739923B1/ko active Active
- 2010-02-03 KR KR1020177008992A patent/KR20170040371A/ko not_active Ceased
- 2010-02-03 KR KR1020177034181A patent/KR101918678B1/ko active Active
- 2010-02-03 MX MX2011008093A patent/MX2011008093A/es not_active Application Discontinuation
- 2010-02-03 RU RU2016100418A patent/RU2655928C1/ru active
- 2010-02-03 US US12/699,864 patent/US8426389B2/en active Active
- 2010-02-03 EP EP10703403.5A patent/EP2393808B1/en active Active
- 2010-02-03 NZ NZ620458A patent/NZ620458A/en unknown
- 2010-02-03 CN CN2010800143630A patent/CN102439006A/zh active Pending
- 2010-02-03 NZ NZ594408A patent/NZ594408A/en active IP Right Revival
- 2010-02-03 CU CU2011000155A patent/CU24089B1/es active IP Right Grant
- 2010-02-03 JP JP2011549242A patent/JP5584705B2/ja active Active
- 2010-02-03 AP AP2011005835A patent/AP2987A/xx active
- 2010-02-03 CA CA2751392A patent/CA2751392C/en active Active
- 2010-02-03 UA UAA201110617A patent/UA114068C2/uk unknown
- 2010-02-03 AU AU2010210627A patent/AU2010210627B2/en active Active
- 2010-02-03 NZ NZ712289A patent/NZ712289A/en unknown
- 2010-02-03 MY MYPI2011003576A patent/MY156354A/en unknown
- 2010-02-03 BR BRPI1008829A patent/BRPI1008829A2/pt not_active Application Discontinuation
- 2010-02-03 CN CN201710063034.9A patent/CN107082790A/zh active Pending
- 2010-02-03 MA MA34136A patent/MA33092B1/fr unknown
- 2010-02-03 RU RU2011136537/04A patent/RU2011136537A/ru not_active Application Discontinuation
- 2010-02-03 MX MX2015007856A patent/MX384300B/es unknown
- 2010-02-03 ES ES10703403T patent/ES2734724T3/es active Active
- 2010-02-03 SG SG10201500207QA patent/SG10201500207QA/en unknown
- 2010-02-03 PE PE2011001433A patent/PE20120585A1/es active IP Right Grant
-
2011
- 2011-08-01 MX MX2020011773A patent/MX2020011773A/es unknown
- 2011-08-01 DO DO2011000251A patent/DOP2011000251A/es unknown
- 2011-08-02 CL CL2011001855A patent/CL2011001855A1/es unknown
- 2011-08-02 IL IL214401A patent/IL214401B/en active IP Right Grant
- 2011-08-02 CO CO11097215A patent/CO6620071A2/es not_active Application Discontinuation
- 2011-08-03 TN TN2011000381A patent/TN2011000381A1/fr unknown
- 2011-08-23 EC EC2011011285A patent/ECSP11011285A/es unknown
- 2011-08-30 CR CR20110464A patent/CR20110464A/es unknown
- 2011-09-01 ZA ZA2011/06412A patent/ZA201106412B/en unknown
-
2013
- 2013-04-22 US US13/867,951 patent/US20130310343A1/en not_active Abandoned
- 2013-08-30 ZA ZA2013/06536A patent/ZA201306536B/en unknown
-
2014
- 2014-01-10 PH PH12014500092A patent/PH12014500092A1/en unknown
-
2015
- 2015-12-04 US US14/959,412 patent/US9624250B2/en active Active
-
2017
- 2017-03-10 US US15/455,463 patent/US9988406B2/en active Active
-
2018
- 2018-05-03 US US15/970,492 patent/US10065947B1/en active Active
- 2018-05-03 US US15/970,486 patent/US10442829B2/en active Active
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