JP2012516147A5 - - Google Patents
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- JP2012516147A5 JP2012516147A5 JP2011546955A JP2011546955A JP2012516147A5 JP 2012516147 A5 JP2012516147 A5 JP 2012516147A5 JP 2011546955 A JP2011546955 A JP 2011546955A JP 2011546955 A JP2011546955 A JP 2011546955A JP 2012516147 A5 JP2012516147 A5 JP 2012516147A5
- Authority
- JP
- Japan
- Prior art keywords
- dna
- protelomerase
- template
- sequence
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 19
- 108020004414 DNA Proteins 0.000 claims 18
- 102000053602 DNA Human genes 0.000 claims 18
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 5
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 5
- 108091026890 Coding region Proteins 0.000 claims 4
- 230000003321 amplification Effects 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108020004638 Circular DNA Proteins 0.000 claims 2
- 238000006073 displacement reaction Methods 0.000 claims 2
- 108700028149 Bacteriophage N15 protelomerase Proteins 0.000 claims 1
- 108020004682 Single-Stranded DNA Proteins 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 244000052769 pathogen Species 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000010076 replication Effects 0.000 claims 1
- 230000003362 replicative effect Effects 0.000 claims 1
- 238000005096 rolling process Methods 0.000 claims 1
- 230000005030 transcription termination Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0901593.4 | 2009-01-30 | ||
| GBGB0901593.4A GB0901593D0 (en) | 2009-01-30 | 2009-01-30 | Production of closed linear DNA |
| PCT/GB2010/000165 WO2010086626A1 (en) | 2009-01-30 | 2010-02-01 | Production of closed linear dna |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015175262A Division JP6454243B2 (ja) | 2009-01-30 | 2015-09-07 | 閉鎖型直鎖状ｄｎａの製造 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012516147A JP2012516147A (ja) | 2012-07-19 |
| JP2012516147A5 true JP2012516147A5 (enExample) | 2013-03-21 |
Family
ID=40469378
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011546955A Pending JP2012516147A (ja) | 2009-01-30 | 2010-02-01 | 閉鎖型直鎖状ｄｎａの製造 |
| JP2015175262A Active JP6454243B2 (ja) | 2009-01-30 | 2015-09-07 | 閉鎖型直鎖状ｄｎａの製造 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015175262A Active JP6454243B2 (ja) | 2009-01-30 | 2015-09-07 | 閉鎖型直鎖状ｄｎａの製造 |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US9109250B2 (enExample) |
| EP (3) | EP3150722B1 (enExample) |
| JP (2) | JP2012516147A (enExample) |
| KR (1) | KR101926662B1 (enExample) |
| CN (2) | CN104911177A (enExample) |
| AU (1) | AU2010209532B2 (enExample) |
| BR (1) | BRPI1005683B1 (enExample) |
| CA (1) | CA2751130C (enExample) |
| DK (2) | DK2391731T3 (enExample) |
| EA (1) | EA021069B1 (enExample) |
| ES (2) | ES2400890T3 (enExample) |
| GB (1) | GB0901593D0 (enExample) |
| IL (1) | IL213930A (enExample) |
| LT (1) | LT3150722T (enExample) |
| MX (1) | MX2011007937A (enExample) |
| NZ (1) | NZ594004A (enExample) |
| SG (1) | SG173102A1 (enExample) |
| WO (1) | WO2010086626A1 (enExample) |
| ZA (1) | ZA201105013B (enExample) |
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| ES2351294B8 (es) * | 2009-07-02 | 2012-06-06 | Consejo Superior De Investigaciones Científicas (Csic) | Metodo para la replicación, amplificación, o secuenciación de un adn molde. |
| GB201013153D0 (en) * | 2010-08-04 | 2010-09-22 | Touchlight Genetics Ltd | Primer for production of closed linear DNA |
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| GB201502645D0 (en) * | 2015-02-17 | 2015-04-01 | Touchlight Genetics Ltd | Method |
| FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
| WO2017109134A1 (en) | 2015-12-22 | 2017-06-29 | Curevac Ag | Method for producing rna molecule compositions |
| RU2616279C1 (ru) * | 2015-12-28 | 2017-04-13 | Федеральное государственное бюджетное учреждение науки Институт биохимии и генетики Уфимского научного центра Российской академии наук (ИБГ УНЦ РАН) | Способ получения маркерных лестниц для гель-электрофоретического определения размеров фрагментов нуклеиновых кислот |
| US10077459B2 (en) | 2016-05-04 | 2018-09-18 | General Electric Company | Cell-free protein expression using rolling circle amplification product |
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| TW201936201A (zh) | 2017-12-14 | 2019-09-16 | 美商堅固生物科技公司 | 基因之非病毒生產及遞送 |
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| CN112639110A (zh) * | 2018-06-22 | 2021-04-09 | 阿斯克肋匹奥生物制药公司 | 用于基因递送以在细胞内持续存在的载体 |
| JP7481755B2 (ja) * | 2018-11-02 | 2024-05-13 | ナイキジェン，リミテッド | 組換えパルボウイルスベクターならびにその作製および使用方法 |
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| KR102014989B1 (ko) | 2013-04-15 | 2019-08-27 | 삼성전자주식회사 | 폴리뉴클레오티드 및 그의 용도 |
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