|
CA2716951A1
(en)
*
|
2008-02-29 |
2009-09-11 |
Array Biopharma Inc. |
Raf inhibitor compounds and methods of use thereof
|
|
JP2011513329A
(ja)
*
|
2008-02-29 |
2011-04-28 |
アレイ バイオファーマ、インコーポレイテッド |
ＲＡＦ阻害化合物として使用されるイミダゾ［４，５−ｂ］ピリジン誘導体
|
|
JP2011513332A
(ja)
*
|
2008-02-29 |
2011-04-28 |
アレイ バイオファーマ、インコーポレイテッド |
癌の治療のためのｒａｆ阻害剤としてのｎ−（６−アミノピリジン−３−イル）−３−（スルホンアミド）ベンズアミド誘導体
|
|
JP2011513331A
(ja)
*
|
2008-02-29 |
2011-04-28 |
アレイ バイオファーマ、インコーポレイテッド |
ピラゾール［３，４−ｂ］ピリジンＲＡＦ阻害剤
|
|
WO2011084486A1
(en)
|
2009-12-21 |
2011-07-14 |
Epitherix, Llc |
1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
|
|
HUE044025T2
(hu)
|
2010-05-20 |
2019-09-30 |
Array Biopharma Inc |
Makrociklusos vegyületek mint TRK-kináz inhibitorok
|
|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
AU2012308570B2
(en)
|
2011-09-14 |
2016-11-10 |
Samumed, Llc |
Indazole-3-carboxamides and their use as Wnt/b-catenin signaling pathway inhibitors
|
|
KR20130077390A
(ko)
*
|
2011-12-29 |
2013-07-09 |
제이더블유중외제약 주식회사 |
단백질 키나아제 저해활성을 가지는 6-아미노-3-카복스아미도인다졸 유도체
|
|
CA2862163A1
(en)
*
|
2012-01-25 |
2013-08-01 |
Bayer Pharma Aktiengesellschaft |
Substituted phenylimidazopyrazoles and use thereof
|
|
PH12017500997A1
(en)
|
2012-04-04 |
2018-02-19 |
Samumed Llc |
Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
|
|
US8889730B2
(en)
*
|
2012-04-10 |
2014-11-18 |
Pfizer Inc. |
Indole and indazole compounds that activate AMPK
|
|
RU2689141C2
(ru)
|
2012-05-04 |
2019-05-24 |
СЭМЬЮМЕД, ЭлЭлСи |
1н-пиразоло[3,4-b]пиридины и их терапевтические применения
|
|
UA125503C2
(uk)
|
2012-06-13 |
2022-04-13 |
Інсайт Холдинґс Корпорейшн |
Заміщені трициклічні сполуки як інгібітори fgfr
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
CN105120862A
(zh)
|
2013-01-08 |
2015-12-02 |
萨穆梅德有限公司 |
Wnt信号途径的3-(苯并咪唑-2-基)-吲唑抑制剂及其治疗应用
|
|
CA2905242C
(en)
*
|
2013-03-15 |
2016-11-29 |
Pfizer Inc. |
Indole compounds that activate ampk
|
|
MY181497A
(en)
|
2013-04-19 |
2020-12-23 |
Incyte Holdings Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2014172639A1
(en)
*
|
2013-04-19 |
2014-10-23 |
Ruga Corporation |
Raf kinase inhibitors
|
|
JP6489658B2
(ja)
*
|
2013-04-25 |
2019-03-27 |
シービーエス バイオサイエンス，カンパニー，リミテッド |
肝細胞癌において分子標的治療の感受性を増加させるための分析方法
|
|
CN103739550B
(zh)
*
|
2014-01-02 |
2016-06-01 |
中国药科大学 |
2,3-二甲基-6-脲-2h-吲唑类化合物及其制备方法与应用
|
|
WO2016040190A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
|
|
WO2016040182A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof
|
|
WO2016040185A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof
|
|
WO2016040184A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
|
WO2016040180A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
|
WO2016040193A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof
|
|
WO2016040188A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
|
WO2016040181A1
(en)
|
2014-09-08 |
2016-03-17 |
Samumed, Llc |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
WO2016096709A1
(en)
|
2014-12-16 |
2016-06-23 |
Eudendron S.R.L. |
Heterocyclic derivatives modulating activity of certain protein kinases
|
|
CR20170390A
(es)
|
2015-02-20 |
2017-10-23 |
Incyte Holdings Corp |
Heterociclos biciclicos como inhibidores de fgfr
|
|
US9580423B2
(en)
|
2015-02-20 |
2017-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
PL3322706T3
(pl)
|
2015-07-16 |
2021-07-19 |
Array Biopharma, Inc. |
Podstawione związki pirazolo[1,5-a]pirydynowe jako inhibitory kinazy ret
|
|
US10226453B2
(en)
|
2015-08-03 |
2019-03-12 |
Samumed, Llc |
3-(1H-indol-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
|
WO2017023972A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
|
WO2017023975A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-pyrrolo[2,3-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
|
|
US10226448B2
(en)
|
2015-08-03 |
2019-03-12 |
Samumed, Llc |
3-(1H-pyrrolo[3,2-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridines and therapeutic uses thereof
|
|
WO2017023984A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof
|
|
WO2017023996A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
|
|
US10166218B2
(en)
|
2015-08-03 |
2019-01-01 |
Samumed, Llc |
3-(1H-indol-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
|
|
US10188634B2
(en)
|
2015-08-03 |
2019-01-29 |
Samumed, Llc |
3-(3H-imidazo[4,5-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
|
US10519169B2
(en)
|
2015-08-03 |
2019-12-31 |
Samumed, Llc |
3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
|
WO2017024010A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
|
|
WO2017023989A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc. |
3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof
|
|
US10206909B2
(en)
|
2015-08-03 |
2019-02-19 |
Samumed, Llc |
3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
|
US10350199B2
(en)
|
2015-08-03 |
2019-07-16 |
Samumed, Llc |
3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof
|
|
US10231956B2
(en)
|
2015-08-03 |
2019-03-19 |
Samumed, Llc |
3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
|
US10329309B2
(en)
|
2015-08-03 |
2019-06-25 |
Samumed, Llc |
3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
|
|
US10285982B2
(en)
|
2015-08-03 |
2019-05-14 |
Samumed, Llc |
3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof
|
|
WO2017023986A1
(en)
|
2015-08-03 |
2017-02-09 |
Samumed, Llc |
3-(1h-indol-2-yl)-1h-indazoles and therapeutic uses thereof
|
|
EP3370721A4
(en)
|
2015-11-06 |
2019-05-22 |
Samumed, LLC |
TREATMENT OF OSTEOARTHRITIS
|
|
WO2017152117A1
(en)
|
2016-03-03 |
2017-09-08 |
Cornell University |
Small molecule ire1-alpha inhibitors
|
|
WO2017178845A1
(en)
|
2016-04-15 |
2017-10-19 |
Cancer Research Technology Limited |
Heterocyclic compounds as ret kinase inhibitors
|
|
CN115650985B
(zh)
|
2016-04-15 |
2024-08-02 |
癌症研究科技有限公司 |
作为ret激酶抑制剂的杂环化合物
|
|
AR108325A1
(es)
|
2016-04-27 |
2018-08-08 |
Samumed Llc |
Isoquinolin-3-il carboxamidas y preparación y uso de las mismas
|
|
SG11201810683VA
(en)
|
2016-06-01 |
2018-12-28 |
Samumed Llc |
Process for preparing n-(5-(3-(7-(3-fluorophenyl)-3h-imidazo[4,5-c]pyridin-2-yl)-1h-indazol-5-yl)pyridin-3-yl)-3-methylbutanamide
|
|
TWI704148B
(zh)
|
2016-10-10 |
2020-09-11 |
美商亞雷生物製藥股份有限公司 |
作為ｒｅｔ激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物
|
|
JOP20190077A1
(ar)
|
2016-10-10 |
2019-04-09 |
Array Biopharma Inc |
مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret
|
|
MX391624B
(es)
|
2016-10-21 |
2025-03-04 |
Samumed Llc |
Métodos de uso de indazol-3-carboxamidas y su uso como inhibidores de la ruta de señalización de wnt/b-catenina.
|
|
KR102558716B1
(ko)
|
2016-11-07 |
2023-07-21 |
사뮤메드, 엘엘씨 |
단일-투여량, 즉시-사용가능한 주사용 제제
|
|
AU2017378487B2
(en)
*
|
2016-12-15 |
2022-03-31 |
The Regents Of The University Of California |
Compositions and methods for treating cancer
|
|
TWI795381B
(zh)
|
2016-12-21 |
2023-03-11 |
比利時商健生藥品公司 |
作為ｍａｌｔ１抑制劑之吡唑衍生物
|
|
US11168090B2
(en)
|
2017-01-18 |
2021-11-09 |
Array Biopharma Inc. |
Substituted pyrazolo[1,5-a]pyrazines as RET kinase inhibitors
|
|
WO2018136663A1
(en)
|
2017-01-18 |
2018-07-26 |
Array Biopharma, Inc. |
Ret inhibitors
|
|
JOP20190213A1
(ar)
|
2017-03-16 |
2019-09-16 |
Array Biopharma Inc |
مركبات حلقية ضخمة كمثبطات لكيناز ros1
|
|
GB201705971D0
(en)
|
2017-04-13 |
2017-05-31 |
Cancer Res Tech Ltd |
Inhibitor compounds
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
WO2019018562A1
(en)
|
2017-07-19 |
2019-01-24 |
Ideaya Biosciences, Inc. |
AMIDO COMPOUND AS MODULATORS OF AHR
|
|
TWI876442B
(zh)
|
2017-10-10 |
2025-03-11 |
美商絡速藥業公司 |
6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之調配物
|
|
TWI791053B
(zh)
|
2017-10-10 |
2023-02-01 |
美商亞雷生物製藥股份有限公司 |
6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之結晶形式及其醫藥組合物
|
|
CN109942544B
(zh)
*
|
2017-12-21 |
2021-06-11 |
中国科学院合肥物质科学研究院 |
一类新型吲唑类衍生物激酶抑制剂
|
|
EP3740486A1
(en)
|
2018-01-18 |
2020-11-25 |
Array Biopharma, Inc. |
Substituted pyrazolyl[4,3-c]pyridinecompounds as ret kinase inhibitors
|
|
CA3087578C
(en)
|
2018-01-18 |
2023-08-08 |
Array Biopharma Inc. |
Substituted pyrazolo[3,4-d]pyrimidine compounds as ret kinase inhibitors
|
|
EP3740491A1
(en)
|
2018-01-18 |
2020-11-25 |
Array Biopharma, Inc. |
Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors
|
|
BR112020022392A2
(pt)
|
2018-05-04 |
2021-02-02 |
Incyte Corporation |
formas sólidas de um inibidor de fgfr e processos para preparação das mesmas
|
|
PE20210919A1
(es)
|
2018-05-04 |
2021-05-19 |
Incyte Corp |
Sales de un inhibidor de fgfr
|
|
EP3790873B1
(en)
*
|
2018-05-07 |
2022-04-27 |
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. |
1h-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors
|
|
JP7296408B2
(ja)
*
|
2018-06-18 |
2023-06-22 |
ヤンセン ファーマシューティカ エヌ．ベー． |
Ｍａｌｔ１阻害剤としてのピラゾール誘導体
|
|
WO2020055672A1
(en)
|
2018-09-10 |
2020-03-19 |
Array Biopharma Inc. |
Fused heterocyclic compounds as ret kinase inhibitors
|
|
AU2019339355A1
(en)
*
|
2018-09-13 |
2021-05-13 |
Bristol-Myers Squibb Company |
Indazole carboxamides as kinase inhibitors
|
|
JP7599411B2
(ja)
|
2018-09-13 |
2024-12-13 |
ブリストル－マイヤーズ スクイブ カンパニー |
受容体相互作用タンパク質キナーゼ１阻害剤（ｒｉｐｋ１）としての１ｈ－インダゾールカルボキサミド
|
|
CN111138426B
(zh)
*
|
2018-11-02 |
2023-03-10 |
安徽中科拓苒药物科学研究有限公司 |
吲唑类激酶抑制剂及其用途
|
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
|
MA55593A
(fr)
|
2019-04-11 |
2022-02-16 |
Janssen Pharmaceutica Nv |
Cycles pyridine contenant des dérivés servant d'inhibiteurs de malt1
|
|
US20220388964A1
(en)
*
|
2019-04-12 |
2022-12-08 |
Hibercell, Inc. |
(aza)indazolyl-aryl sulfonamide and related compounds and their use in treating medical conditions
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
KR20220079593A
(ko)
|
2019-10-03 |
2022-06-13 |
브리스톨-마이어스 스큅 컴퍼니 |
키나제 억제제로서의 인다졸 카르복스아미드
|
|
GEP20247679B
(en)
|
2019-10-14 |
2024-10-10 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2021076728A1
(en)
|
2019-10-16 |
2021-04-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
CN112794820B
(zh)
*
|
2019-11-14 |
2022-06-07 |
四川大学 |
吲唑类衍生物及其制备方法和用途
|
|
PE20221504A1
(es)
|
2019-12-04 |
2022-09-30 |
Incyte Corp |
Derivados de un inhibidor de fgfr
|
|
JP7720840B2
(ja)
|
2019-12-04 |
2025-08-08 |
インサイト・コーポレイション |
Ｆｇｆｒ阻害剤としての三環式複素環
|
|
WO2021146424A1
(en)
|
2020-01-15 |
2021-07-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
TW202304459A
(zh)
|
2021-04-12 |
2023-02-01 |
美商英塞特公司 |
包含ｆｇｆｒ抑制劑及ｎｅｃｔｉｎ－４靶向劑之組合療法
|
|
CA3220155A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
TW202313611A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為ｆｇｆｒ抑制劑之三環雜環
|