JP2019530708A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019530708A5 JP2019530708A5 JP2019519329A JP2019519329A JP2019530708A5 JP 2019530708 A5 JP2019530708 A5 JP 2019530708A5 JP 2019519329 A JP2019519329 A JP 2019519329A JP 2019519329 A JP2019519329 A JP 2019519329A JP 2019530708 A5 JP2019530708 A5 JP 2019530708A5
- Authority
- JP
- Japan
- Prior art keywords
- methoxy
- carbonitrile
- amino
- quinoxaline
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662406328P | 2016-10-10 | 2016-10-10 | |
| US62/406,328 | 2016-10-10 | ||
| PCT/US2017/055809 WO2018071348A1 (en) | 2016-10-10 | 2017-10-09 | Quinoxaline compounds as type iii receptor tyrosine kinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019530708A JP2019530708A (ja) | 2019-10-24 |
| JP2019530708A5 true JP2019530708A5 (enExample) | 2020-11-12 |
| JP7206188B2 JP7206188B2 (ja) | 2023-01-17 |
Family
ID=61905910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019519329A Active JP7206188B2 (ja) | 2016-10-10 | 2017-10-09 | Ｉｉｉ型受容体チロシンキナーゼ阻害剤としてのキノキサリン化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10689362B2 (enExample) |
| EP (1) | EP3523285A4 (enExample) |
| JP (1) | JP7206188B2 (enExample) |
| KR (1) | KR102609813B1 (enExample) |
| CN (1) | CN110325515B (enExample) |
| AU (1) | AU2017342928B2 (enExample) |
| BR (1) | BR112019007271A2 (enExample) |
| CA (1) | CA3039919A1 (enExample) |
| IL (1) | IL265829B (enExample) |
| RU (1) | RU2019113764A (enExample) |
| SG (1) | SG11201903091VA (enExample) |
| TW (1) | TWI648266B (enExample) |
| WO (1) | WO2018071348A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020271855B2 (en) | 2019-04-12 | 2025-11-27 | National Health Research Institutes | Heterocyclic compounds as kinase inhibitors for therapeutic uses |
| JP2023542041A (ja) * | 2020-09-21 | 2023-10-04 | ハチソン メディファルマ リミテッド | ヘテロ芳香族化合物及びその使用 |
| JP2024515976A (ja) * | 2021-04-26 | 2024-04-11 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 骨格再生のための機能不全骨格幹細胞の生化学的活性化 |
| WO2023082145A1 (en) * | 2021-11-11 | 2023-05-19 | 4B Technologies (Suzhou) Limited | Intermediate compound of quinoxaline and preparation process thereof |
| CN114605391B (zh) * | 2022-02-21 | 2024-01-26 | 广州六顺生物科技股份有限公司 | 喹喔啉类衍生物及其制备方法和应用 |
| CN115141177B (zh) * | 2022-08-30 | 2022-12-09 | 福贝生物科技(苏州)有限公司 | 喹喔啉类化合物马来酸盐的新晶型及其制备方法 |
| CN121793964A (zh) * | 2023-07-18 | 2026-04-03 | 安立玺荣生医股份有限公司 | 增强喹喔啉iii型受体酪氨酸激酶抑制剂的吸收的方法 |
| CN121969370A (zh) | 2023-09-28 | 2026-05-01 | 福贝生物医药科技(北京)有限公司 | 一种固体分散体、药物组合物、其制备方法及其用途 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69622183D1 (de) * | 1995-11-07 | 2002-08-08 | Kirin Brewery | Chinolinderivate und chinazolinderivate welche die autophosphorylierung des von blutplättchen abstammenden wachstumsfaktorrezeptors inhibiren und sie enthaltende pharmazeutische zusammensetzungen |
| WO2000023444A1 (en) * | 1998-10-21 | 2000-04-27 | Abbott Laboratories | 5,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds |
| US7304092B1 (en) * | 2002-11-12 | 2007-12-04 | Yale University | Compounds and methods for treating tumors, cancer and hyperproliferative diseases |
| FR2856686A1 (fr) * | 2003-06-25 | 2004-12-31 | Sod Conseils Rech Applic | Benzothiazole-4,7-diones et benzooxazole-4,7-diones substituees en position 5 ou 6 et leurs procedes de preparation |
| GB0509227D0 (en) * | 2005-05-05 | 2005-06-15 | Chroma Therapeutics Ltd | Intracellular enzyme inhibitors |
| CN101432281B (zh) * | 2006-04-19 | 2013-08-28 | 诺瓦提斯公司 | 6-0-取代的苯并*唑和苯并噻唑化合物以及抑制csf-1r信号传导的方法 |
| KR101464385B1 (ko) | 2006-04-19 | 2014-11-21 | 노파르티스 아게 | ６-ｏ-치환된 벤즈옥사졸 및 벤조티아졸 화합물, 및 ｃｓｆ-１ｒ 신호전달의 억제 방법 |
| WO2008063888A2 (en) * | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| AU2009248774B2 (en) * | 2008-05-23 | 2012-05-31 | Novartis Ag | Derivatives of quinolines and quinoxalines as protein tyrosine kinase inhibitors |
| WO2011026579A1 (en) * | 2009-09-04 | 2011-03-10 | Bayer Schering Pharma Aktiengesellschaft | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors |
| GB201007286D0 (en) * | 2010-04-30 | 2010-06-16 | Astex Therapeutics Ltd | New compounds |
| GB201020179D0 (en) * | 2010-11-29 | 2011-01-12 | Astex Therapeutics Ltd | New compounds |
| GB201118654D0 (en) * | 2011-10-28 | 2011-12-07 | Astex Therapeutics Ltd | New compounds |
| EP2806874B1 (en) * | 2012-01-25 | 2017-11-15 | Neupharma, Inc. | Quinoxaline-oxy-phenyl derivatives as kinase inhibitors |
| WO2013157540A1 (ja) * | 2012-04-17 | 2013-10-24 | 富士フイルム株式会社 | 含窒素複素環化合物またはその塩 |
| US9725421B2 (en) | 2012-11-12 | 2017-08-08 | Neupharma, Inc. | Substituted quinoxalines as B-raf kinase inhibitors |
| US10517844B2 (en) * | 2014-11-13 | 2019-12-31 | Buck Institute For Research On Aging | Inhibition of proline catabolism for the treatment of cancer and other therapeutic applications |
-
2017
- 2017-10-09 SG SG11201903091VA patent/SG11201903091VA/en unknown
- 2017-10-09 WO PCT/US2017/055809 patent/WO2018071348A1/en not_active Ceased
- 2017-10-09 RU RU2019113764A patent/RU2019113764A/ru not_active Application Discontinuation
- 2017-10-09 BR BR112019007271A patent/BR112019007271A2/pt not_active Application Discontinuation
- 2017-10-09 CN CN201780075303.1A patent/CN110325515B/zh active Active
- 2017-10-09 CA CA3039919A patent/CA3039919A1/en active Pending
- 2017-10-09 AU AU2017342928A patent/AU2017342928B2/en active Active
- 2017-10-09 JP JP2019519329A patent/JP7206188B2/ja active Active
- 2017-10-09 KR KR1020197012725A patent/KR102609813B1/ko active Active
- 2017-10-09 US US16/340,685 patent/US10689362B2/en active Active
- 2017-10-09 EP EP17859434.7A patent/EP3523285A4/en active Pending
- 2017-10-11 TW TW106134711A patent/TWI648266B/zh active
-
2019
- 2019-04-04 IL IL265829A patent/IL265829B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2019113764A (ru) | Соединения хиноксалина в качестве ингибиторов рецепторной тирозинкиназы iii типа | |
| US7074801B1 (en) | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | |
| KR101985050B1 (ko) | 피라진카르복사미드 화합물 | |
| RU2417994C2 (ru) | Производные пиразина, полезные в качестве антагонистов аденозинового рецептора | |
| JP2022531801A5 (enExample) | ||
| JP2010513444A5 (enExample) | ||
| TWI628174B (zh) | 新穎吡啶衍生物 | |
| JP2020503299A5 (enExample) | ||
| RU2016102137A (ru) | Первичные карбоксамиды в качестве ингибиторов bik | |
| JP2017512794A5 (enExample) | ||
| RU2642779C2 (ru) | Ингибиторы сомт | |
| RU2016141088A (ru) | 5-замещённые индазол-3-карбоксамиды и их получение и применение | |
| RU2016141646A (ru) | Ингибиторы trka киназы, основанные на них композиции и способы | |
| JP2016523911A5 (enExample) | ||
| HRP20180546T1 (hr) | Supstituirani benzilindazoli za uporabu kao inhibitori bub1 kinaze za liječenje hiperproliferativnih bolesti | |
| TW200536851A (en) | Compounds and methods of use | |
| AU2006236387A1 (en) | Subtituted heteroaryl CB1 antagonists | |
| JP2012510989A5 (enExample) | ||
| JP2019523266A5 (enExample) | ||
| US20160272621A1 (en) | Gsk-3 inhibitors | |
| HRP20160359T1 (hr) | Derivati kinazolindiona, njihovo dobivanje i njihove terapijske primjene | |
| JP2020512401A5 (enExample) | ||
| JP5487100B2 (ja) | アデノシンａ３受容体リガンドとしてのトリアゾロ［１，５−ａ］キノリン | |
| HRP20201400T1 (hr) | Spojevi 6-aril-4-(morfolin-4-il)-1h-piridin-2-ona korisni za liječenje karcinoma i dijabetesa | |
| JP2017500287A (ja) | Ｇｓｋ−３阻害剤として有用な置換ピリジン誘導体 |