JP2012510814A5 - - Google Patents
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- Publication number
- JP2012510814A5 JP2012510814A5 JP2011539625A JP2011539625A JP2012510814A5 JP 2012510814 A5 JP2012510814 A5 JP 2012510814A5 JP 2011539625 A JP2011539625 A JP 2011539625A JP 2011539625 A JP2011539625 A JP 2011539625A JP 2012510814 A5 JP2012510814 A5 JP 2012510814A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antigen
- monoclonal antibody
- binding fragment
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 9
- 102000036639 antigens Human genes 0.000 claims 9
- 108091007433 antigens Proteins 0.000 claims 9
- 239000012634 fragment Substances 0.000 claims 9
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- 208000007502 anemia Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 102000001554 Hemoglobins Human genes 0.000 claims 1
- 108010054147 Hemoglobins Proteins 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 101000637813 Homo sapiens Solute carrier family 40 member 1 Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000022400 anemia due to chronic disease Diseases 0.000 claims 1
- 238000004820 blood count Methods 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 230000010437 erythropoiesis Effects 0.000 claims 1
- 238000005534 hematocrit Methods 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000002831 pharmacologic agent Substances 0.000 claims 1
- 210000001995 reticulocyte Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12007608P | 2008-12-05 | 2008-12-05 | |
| US61/120,076 | 2008-12-05 | ||
| US23981809P | 2009-09-04 | 2009-09-04 | |
| US61/239,818 | 2009-09-04 | ||
| PCT/US2009/066187 WO2010065496A1 (en) | 2008-12-05 | 2009-12-01 | Anti-ferroportin 1 monoclonal antibodies and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012510814A JP2012510814A (ja) | 2012-05-17 |
| JP2012510814A5 true JP2012510814A5 (enExample) | 2013-01-24 |
| JP5713917B2 JP5713917B2 (ja) | 2015-05-07 |
Family
ID=41683589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539625A Expired - Fee Related JP5713917B2 (ja) | 2008-12-05 | 2009-12-01 | 抗フェロポーチン１モノクローナル抗体およびその使用 |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP2373335B1 (enExample) |
| JP (1) | JP5713917B2 (enExample) |
| KR (1) | KR101353117B1 (enExample) |
| CN (1) | CN102238962B (enExample) |
| AR (1) | AR074398A1 (enExample) |
| AU (1) | AU2009322587B2 (enExample) |
| BR (1) | BRPI0922288A2 (enExample) |
| CA (1) | CA2745618C (enExample) |
| CY (1) | CY1117355T1 (enExample) |
| DK (1) | DK2373335T3 (enExample) |
| EA (1) | EA020472B1 (enExample) |
| ES (1) | ES2566343T3 (enExample) |
| HR (1) | HRP20160302T1 (enExample) |
| HU (1) | HUE028585T2 (enExample) |
| IL (1) | IL212731A0 (enExample) |
| MX (1) | MX2011005939A (enExample) |
| NZ (1) | NZ592545A (enExample) |
| PA (1) | PA8849601A1 (enExample) |
| PL (1) | PL2373335T3 (enExample) |
| SG (1) | SG171960A1 (enExample) |
| SI (1) | SI2373335T1 (enExample) |
| TW (1) | TW201023891A (enExample) |
| UA (1) | UA104741C2 (enExample) |
| WO (1) | WO2010065496A1 (enExample) |
| ZA (1) | ZA201103941B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104284677A (zh) * | 2012-05-14 | 2015-01-14 | 霍夫曼-拉罗奇有限公司 | 用于肿瘤诊断和治疗的组合物和方法 |
| EP3788065B1 (en) | 2018-04-30 | 2025-08-27 | The Children's Hospital Of Philadelphia | Improving anemias by combining agents |
| KR20220088699A (ko) | 2019-09-27 | 2022-06-28 | 디스크 메디슨, 인크. | 골수섬유증 및 관련 상태의 치료 방법 |
| CN110806486B (zh) * | 2019-11-23 | 2023-03-21 | 中南大学湘雅三医院 | Mafg/as1/pcbp2/fpn1调控轴作为靶位点检测试剂的应用 |
| KR20230012539A (ko) | 2020-05-13 | 2023-01-26 | 디스크 메디슨, 인크. | 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체 |
| CN113980987A (zh) * | 2021-12-06 | 2022-01-28 | 上海市农业科学院 | 一种提高植物抗镍性能的PgIREG1S和AlATP-PRTS双基因组及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7166448B1 (en) * | 1999-05-10 | 2007-01-23 | Children's Medical Center Corproation | Ferroportin1 nucleic acids and proteins |
| IT1319221B1 (it) * | 2000-10-17 | 2003-09-26 | Antonello Pietrangelo | Mutazioni nel gene della ferroportina 1 associata ad emocromatosiereditaria. |
| CA2711826C (en) * | 2008-01-25 | 2018-02-27 | Amgen Inc. | Ferroportin antibodies and methods of use |
-
2009
- 2009-11-23 PA PA20098849601A patent/PA8849601A1/es unknown
- 2009-11-24 AR ARP090104529A patent/AR074398A1/es unknown
- 2009-11-25 TW TW098140185A patent/TW201023891A/zh unknown
- 2009-12-01 SG SG2011040797A patent/SG171960A1/en unknown
- 2009-12-01 CN CN200980148354.8A patent/CN102238962B/zh not_active Expired - Fee Related
- 2009-12-01 EP EP09760073.8A patent/EP2373335B1/en active Active
- 2009-12-01 CA CA2745618A patent/CA2745618C/en not_active Expired - Fee Related
- 2009-12-01 KR KR1020117014053A patent/KR101353117B1/ko not_active Expired - Fee Related
- 2009-12-01 NZ NZ592545A patent/NZ592545A/xx not_active IP Right Cessation
- 2009-12-01 EA EA201170764A patent/EA020472B1/ru not_active IP Right Cessation
- 2009-12-01 HR HRP20160302TT patent/HRP20160302T1/hr unknown
- 2009-12-01 AU AU2009322587A patent/AU2009322587B2/en not_active Ceased
- 2009-12-01 BR BRPI0922288A patent/BRPI0922288A2/pt not_active IP Right Cessation
- 2009-12-01 ES ES09760073.8T patent/ES2566343T3/es active Active
- 2009-12-01 MX MX2011005939A patent/MX2011005939A/es active IP Right Grant
- 2009-12-01 DK DK09760073.8T patent/DK2373335T3/en active
- 2009-12-01 JP JP2011539625A patent/JP5713917B2/ja not_active Expired - Fee Related
- 2009-12-01 PL PL09760073T patent/PL2373335T3/pl unknown
- 2009-12-01 WO PCT/US2009/066187 patent/WO2010065496A1/en not_active Ceased
- 2009-12-01 SI SI200931382T patent/SI2373335T1/sl unknown
- 2009-12-01 UA UAA201107028A patent/UA104741C2/uk unknown
- 2009-12-01 HU HUE09760073A patent/HUE028585T2/en unknown
-
2011
- 2011-05-05 IL IL212731A patent/IL212731A0/en unknown
- 2011-05-27 ZA ZA2011/03941A patent/ZA201103941B/en unknown
-
2016
- 2016-04-12 CY CY20161100296T patent/CY1117355T1/el unknown
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