JP2012510814A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012510814A5 JP2012510814A5 JP2011539625A JP2011539625A JP2012510814A5 JP 2012510814 A5 JP2012510814 A5 JP 2012510814A5 JP 2011539625 A JP2011539625 A JP 2011539625A JP 2011539625 A JP2011539625 A JP 2011539625A JP 2012510814 A5 JP2012510814 A5 JP 2012510814A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antigen
- monoclonal antibody
- binding fragment
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 9
- 102000036639 antigens Human genes 0.000 claims 9
- 108091007433 antigens Proteins 0.000 claims 9
- 239000012634 fragment Substances 0.000 claims 9
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- 208000007502 anemia Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 102000001554 Hemoglobins Human genes 0.000 claims 1
- 108010054147 Hemoglobins Proteins 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 101000637813 Homo sapiens Solute carrier family 40 member 1 Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000022400 anemia due to chronic disease Diseases 0.000 claims 1
- 238000004820 blood count Methods 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 230000010437 erythropoiesis Effects 0.000 claims 1
- 238000005534 hematocrit Methods 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000002831 pharmacologic agent Substances 0.000 claims 1
- 210000001995 reticulocyte Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12007608P | 2008-12-05 | 2008-12-05 | |
| US61/120,076 | 2008-12-05 | ||
| US23981809P | 2009-09-04 | 2009-09-04 | |
| US61/239,818 | 2009-09-04 | ||
| PCT/US2009/066187 WO2010065496A1 (en) | 2008-12-05 | 2009-12-01 | Anti-ferroportin 1 monoclonal antibodies and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012510814A JP2012510814A (ja) | 2012-05-17 |
| JP2012510814A5 true JP2012510814A5 (enExample) | 2013-01-24 |
| JP5713917B2 JP5713917B2 (ja) | 2015-05-07 |
Family
ID=41683589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011539625A Expired - Fee Related JP5713917B2 (ja) | 2008-12-05 | 2009-12-01 | 抗フェロポーチン１モノクローナル抗体およびその使用 |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP2373335B1 (enExample) |
| JP (1) | JP5713917B2 (enExample) |
| KR (1) | KR101353117B1 (enExample) |
| CN (1) | CN102238962B (enExample) |
| AR (1) | AR074398A1 (enExample) |
| AU (1) | AU2009322587B2 (enExample) |
| BR (1) | BRPI0922288A2 (enExample) |
| CA (1) | CA2745618C (enExample) |
| CY (1) | CY1117355T1 (enExample) |
| DK (1) | DK2373335T3 (enExample) |
| EA (1) | EA020472B1 (enExample) |
| ES (1) | ES2566343T3 (enExample) |
| HR (1) | HRP20160302T1 (enExample) |
| HU (1) | HUE028585T2 (enExample) |
| IL (1) | IL212731A0 (enExample) |
| MX (1) | MX2011005939A (enExample) |
| NZ (1) | NZ592545A (enExample) |
| PA (1) | PA8849601A1 (enExample) |
| PL (1) | PL2373335T3 (enExample) |
| SG (1) | SG171960A1 (enExample) |
| SI (1) | SI2373335T1 (enExample) |
| TW (1) | TW201023891A (enExample) |
| UA (1) | UA104741C2 (enExample) |
| WO (1) | WO2010065496A1 (enExample) |
| ZA (1) | ZA201103941B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014027905A2 (pt) * | 2012-05-14 | 2017-06-27 | Genentech Inc | anticorpo, célula, ácido nucleico, métodos de identificação de um primeiro anticorpo, de inibição do crescimento de uma célula, de tratamento terapêutico, de determinação da presença de uma proteína, de diagnóstico da presença de um tumor e de distribuição de agente citotóxico. |
| WO2019213016A1 (en) | 2018-04-30 | 2019-11-07 | The Children's Hospital Of Philadelphia | Methods of improving anemias by combining agents |
| CA3156007A1 (en) | 2019-09-27 | 2021-04-01 | Disc Medicine, Inc. | METHODS OF TREATING MYELOFIBROSE AND ASSOCIATED CONDITIONS |
| CN110806486B (zh) * | 2019-11-23 | 2023-03-21 | 中南大学湘雅三医院 | Mafg/as1/pcbp2/fpn1调控轴作为靶位点检测试剂的应用 |
| AU2021273014A1 (en) | 2020-05-13 | 2022-11-17 | AbbVie Deutschland GmbH & Co. KG | Anti-hemojuvelin (HJV) antibodies for treating anemia of chronic disease |
| ES3075793T3 (en) | 2020-05-13 | 2026-08-07 | Disc Medicine Inc | Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis |
| CN113980987A (zh) * | 2021-12-06 | 2022-01-28 | 上海市农业科学院 | 一种提高植物抗镍性能的PgIREG1S和AlATP-PRTS双基因组及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7166448B1 (en) * | 1999-05-10 | 2007-01-23 | Children's Medical Center Corproation | Ferroportin1 nucleic acids and proteins |
| IT1319221B1 (it) * | 2000-10-17 | 2003-09-26 | Antonello Pietrangelo | Mutazioni nel gene della ferroportina 1 associata ad emocromatosiereditaria. |
| EP2803675A3 (en) * | 2008-01-25 | 2014-12-24 | Amgen, Inc | Ferroportin antibodies and methods of use |
-
2009
- 2009-11-23 PA PA20098849601A patent/PA8849601A1/es unknown
- 2009-11-24 AR ARP090104529A patent/AR074398A1/es unknown
- 2009-11-25 TW TW098140185A patent/TW201023891A/zh unknown
- 2009-12-01 DK DK09760073.8T patent/DK2373335T3/en active
- 2009-12-01 EA EA201170764A patent/EA020472B1/ru not_active IP Right Cessation
- 2009-12-01 MX MX2011005939A patent/MX2011005939A/es active IP Right Grant
- 2009-12-01 ES ES09760073.8T patent/ES2566343T3/es active Active
- 2009-12-01 UA UAA201107028A patent/UA104741C2/uk unknown
- 2009-12-01 KR KR1020117014053A patent/KR101353117B1/ko not_active Expired - Fee Related
- 2009-12-01 JP JP2011539625A patent/JP5713917B2/ja not_active Expired - Fee Related
- 2009-12-01 BR BRPI0922288A patent/BRPI0922288A2/pt not_active IP Right Cessation
- 2009-12-01 SG SG2011040797A patent/SG171960A1/en unknown
- 2009-12-01 NZ NZ592545A patent/NZ592545A/xx not_active IP Right Cessation
- 2009-12-01 AU AU2009322587A patent/AU2009322587B2/en not_active Ceased
- 2009-12-01 EP EP09760073.8A patent/EP2373335B1/en active Active
- 2009-12-01 SI SI200931382T patent/SI2373335T1/sl unknown
- 2009-12-01 PL PL09760073T patent/PL2373335T3/pl unknown
- 2009-12-01 CN CN200980148354.8A patent/CN102238962B/zh not_active Expired - Fee Related
- 2009-12-01 WO PCT/US2009/066187 patent/WO2010065496A1/en not_active Ceased
- 2009-12-01 HR HRP20160302TT patent/HRP20160302T1/hr unknown
- 2009-12-01 CA CA2745618A patent/CA2745618C/en not_active Expired - Fee Related
- 2009-12-01 HU HUE09760073A patent/HUE028585T2/en unknown
-
2011
- 2011-05-05 IL IL212731A patent/IL212731A0/en unknown
- 2011-05-27 ZA ZA2011/03941A patent/ZA201103941B/en unknown
-
2016
- 2016-04-12 CY CY20161100296T patent/CY1117355T1/el unknown