CA2745618C - Anti-ferroportin 1 monoclonal antibodies and uses thereof - Google Patents
Anti-ferroportin 1 monoclonal antibodies and uses thereof Download PDFInfo
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- CA2745618C CA2745618C CA2745618A CA2745618A CA2745618C CA 2745618 C CA2745618 C CA 2745618C CA 2745618 A CA2745618 A CA 2745618A CA 2745618 A CA2745618 A CA 2745618A CA 2745618 C CA2745618 C CA 2745618C
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Hematology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12007608P | 2008-12-05 | 2008-12-05 | |
| US61/120,076 | 2008-12-05 | ||
| US23981809P | 2009-09-04 | 2009-09-04 | |
| US61/239,818 | 2009-09-04 | ||
| PCT/US2009/066187 WO2010065496A1 (en) | 2008-12-05 | 2009-12-01 | Anti-ferroportin 1 monoclonal antibodies and uses thereof |
Publications (2)
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|---|---|
| CA2745618A1 CA2745618A1 (en) | 2010-06-10 |
| CA2745618C true CA2745618C (en) | 2014-06-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2745618A Expired - Fee Related CA2745618C (en) | 2008-12-05 | 2009-12-01 | Anti-ferroportin 1 monoclonal antibodies and uses thereof |
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| KR (1) | KR101353117B1 (enExample) |
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| UA (1) | UA104741C2 (enExample) |
| WO (1) | WO2010065496A1 (enExample) |
| ZA (1) | ZA201103941B (enExample) |
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| CN104284677A (zh) * | 2012-05-14 | 2015-01-14 | 霍夫曼-拉罗奇有限公司 | 用于肿瘤诊断和治疗的组合物和方法 |
| EP3788065B1 (en) | 2018-04-30 | 2025-08-27 | The Children's Hospital Of Philadelphia | Improving anemias by combining agents |
| KR20220088699A (ko) | 2019-09-27 | 2022-06-28 | 디스크 메디슨, 인크. | 골수섬유증 및 관련 상태의 치료 방법 |
| CN110806486B (zh) * | 2019-11-23 | 2023-03-21 | 中南大学湘雅三医院 | Mafg/as1/pcbp2/fpn1调控轴作为靶位点检测试剂的应用 |
| KR20230012539A (ko) | 2020-05-13 | 2023-01-26 | 디스크 메디슨, 인크. | 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체 |
| CN113980987A (zh) * | 2021-12-06 | 2022-01-28 | 上海市农业科学院 | 一种提高植物抗镍性能的PgIREG1S和AlATP-PRTS双基因组及其应用 |
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| US7166448B1 (en) * | 1999-05-10 | 2007-01-23 | Children's Medical Center Corproation | Ferroportin1 nucleic acids and proteins |
| IT1319221B1 (it) * | 2000-10-17 | 2003-09-26 | Antonello Pietrangelo | Mutazioni nel gene della ferroportina 1 associata ad emocromatosiereditaria. |
| CA2711826C (en) * | 2008-01-25 | 2018-02-27 | Amgen Inc. | Ferroportin antibodies and methods of use |
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2016
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Also Published As
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| MX2011005939A (es) | 2011-06-27 |
| EP2373335B1 (en) | 2016-02-24 |
| JP2012510814A (ja) | 2012-05-17 |
| AR074398A1 (es) | 2011-01-12 |
| ES2566343T3 (es) | 2016-04-12 |
| CN102238962A (zh) | 2011-11-09 |
| JP5713917B2 (ja) | 2015-05-07 |
| ZA201103941B (en) | 2012-11-28 |
| NZ592545A (en) | 2012-12-21 |
| AU2009322587B2 (en) | 2013-09-26 |
| TW201023891A (en) | 2010-07-01 |
| DK2373335T3 (en) | 2016-05-02 |
| HRP20160302T1 (hr) | 2016-04-22 |
| PA8849601A1 (es) | 2010-07-27 |
| CN102238962B (zh) | 2014-02-12 |
| HK1158977A1 (zh) | 2012-07-27 |
| UA104741C2 (uk) | 2014-03-11 |
| CA2745618A1 (en) | 2010-06-10 |
| BRPI0922288A2 (pt) | 2018-08-28 |
| EA020472B1 (ru) | 2014-11-28 |
| EP2373335A1 (en) | 2011-10-12 |
| CY1117355T1 (el) | 2017-04-26 |
| AU2009322587A1 (en) | 2011-07-28 |
| SI2373335T1 (sl) | 2016-04-29 |
| IL212731A0 (en) | 2011-07-31 |
| SG171960A1 (en) | 2011-07-28 |
| KR20110084996A (ko) | 2011-07-26 |
| WO2010065496A1 (en) | 2010-06-10 |
| PL2373335T3 (pl) | 2016-08-31 |
| EA201170764A1 (ru) | 2011-12-30 |
| HUE028585T2 (en) | 2016-12-28 |
| KR101353117B1 (ko) | 2014-02-17 |
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