JP2012510803A5 - - Google Patents

Info

Publication number

JP2012510803A5

JP2012510803A5 JP2011539034A JP2011539034A JP2012510803A5 JP 2012510803 A5 JP2012510803 A5 JP 2012510803A5 JP 2011539034 A JP2011539034 A JP 2011539034A JP 2011539034 A JP2011539034 A JP 2011539034A JP 2012510803 A5 JP2012510803 A5 JP 2012510803A5

Authority

JP

Japan

Prior art keywords

isolated

isolated peptide

nucleic acid

protease

seq

Prior art date

2009-12-04

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 108090000765 processed proteins & peptides Proteins 0.000 claims 9
• 108091005804 Peptidases Proteins 0.000 claims 7
• 239000004365 Protease Substances 0.000 claims 7
• 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 6
• 150000007523 nucleic acids Chemical class 0.000 claims 5
• 108020004707 nucleic acids Proteins 0.000 claims 4
• 102000039446 nucleic acids Human genes 0.000 claims 4
• 125000003275 alpha amino acid group Chemical group 0.000 claims 3
• 239000000203 mixture Substances 0.000 claims 3
• 230000001225 therapeutic effect Effects 0.000 claims 3
• 229940122199 Insulin secretagogue Drugs 0.000 claims 2
• 206010012601 diabetes mellitus Diseases 0.000 claims 2
• 108090000317 Chymotrypsin Proteins 0.000 claims 1
• 102100025101 GATA-type zinc finger protein 1 Human genes 0.000 claims 1
• 101710198884 GATA-type zinc finger protein 1 Proteins 0.000 claims 1
• DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical group C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 claims 1
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
• 208000008589 Obesity Diseases 0.000 claims 1
• 102000035195 Peptidases Human genes 0.000 claims 1
• 241000235648 Pichia Species 0.000 claims 1
• 102000007562 Serum Albumin Human genes 0.000 claims 1
• 108010071390 Serum Albumin Proteins 0.000 claims 1
• 108090000631 Trypsin Proteins 0.000 claims 1
• 102000004142 Trypsin Human genes 0.000 claims 1
• 229960002376 chymotrypsin Drugs 0.000 claims 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
• 208000035475 disorder Diseases 0.000 claims 1
• 238000010255 intramuscular injection Methods 0.000 claims 1
• 238000010253 intravenous injection Methods 0.000 claims 1
• 235000020824 obesity Nutrition 0.000 claims 1
• 238000010254 subcutaneous injection Methods 0.000 claims 1
• 239000012588 trypsin Substances 0.000 claims 1