JP2012509272A - 核酸送達系のための放出性カチオン脂質 - Google Patents
核酸送達系のための放出性カチオン脂質 Download PDFInfo
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Cited By (3)
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| JP2015007021A (ja) * | 2013-06-26 | 2015-01-15 | 富士フイルム株式会社 | 脂質粒子、核酸送達キャリア、核酸送達キャリア製造用組成物、脂質粒子の製造方法及び遺伝子導入方法 |
| WO2016121942A1 (ja) * | 2015-01-30 | 2016-08-04 | 日油株式会社 | カチオン性脂質 |
| JP2022516318A (ja) * | 2019-01-04 | 2022-02-25 | オンコラス， インコーポレイテッド | カプセル化ポリヌクレオチド及び使用方法 |
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| CA2742689A1 (en) * | 2008-11-17 | 2010-05-20 | Enzon Pharmaceuticals, Inc. | Branched cationic lipids for nucleic acids delivery system |
| CN101870719B (zh) * | 2010-05-21 | 2013-09-25 | 中国科学院上海有机化学研究所 | 一种同时具有二硫化学键和甾体骨架结构的有机功能化合物、制备方法和用途 |
| CN102161688B (zh) * | 2011-02-18 | 2013-09-04 | 中国科学院上海有机化学研究所 | 一种含有胆固醇结构片段的生物相容性合成脂质体、制备方法及其应用 |
| CN104011210B (zh) | 2011-10-11 | 2018-05-01 | 布里格姆及妇女医院股份有限公司 | 神经退行性病症中的microRNA |
| US9579338B2 (en) | 2011-11-04 | 2017-02-28 | Nitto Denko Corporation | Method of producing lipid nanoparticles for drug delivery |
| CN103906504B (zh) * | 2011-11-04 | 2017-11-17 | 日东电工株式会社 | 制备用于药物递送的脂质纳米颗粒的方法 |
| CA2858884A1 (en) | 2011-12-12 | 2013-06-20 | The Trustees Of The University Of Pennsylvania | Proteins comprising mrsa pbp2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat mrsa infections |
| CN102911252B (zh) * | 2012-10-25 | 2014-07-16 | 四川大学 | 含肽类树状分子的阳离子脂质、转基因载体及其制备方法和应用 |
| AU2013355258A1 (en) * | 2012-12-07 | 2015-06-11 | Alnylam Pharmaceuticals, Inc. | Improved nucleic acid lipid particle formulations |
| DK2992874T3 (en) | 2013-04-30 | 2018-11-12 | Delta Fly Pharma Inc | LIPOSOM FOR TOPIC SUBMISSION AND USE THEREOF |
| WO2015021465A2 (en) * | 2013-08-09 | 2015-02-12 | New York University | Protein engineered systems for delivery of molecules |
| WO2015178438A1 (ja) * | 2014-05-20 | 2015-11-26 | アルケア株式会社 | 皮膚用粘着剤組成物及び皮膚用貼付材 |
| AU2015337909B2 (en) | 2014-10-30 | 2018-12-13 | Delta-Fly Pharma, Inc. | New production method of lipoplex for local administration and antitumor drug using lipoplex |
| US11459568B2 (en) | 2016-10-31 | 2022-10-04 | University Of Massachusetts | Targeting microRNA-101-3p in cancer therapy |
| EP3315125A1 (en) * | 2016-10-31 | 2018-05-02 | Silence Therapeutics (London) Ltd | Lipid nanoparticle formulation |
| CN106565763B (zh) * | 2016-11-11 | 2017-12-15 | 深圳市声光动力生物医药科技有限公司 | pH敏感的轴向取代硅酞菁配合物及其制备方法和在医药上的应用 |
| CN113166783B (zh) | 2018-10-09 | 2024-10-11 | 不列颠哥伦比亚大学 | 包含无有机溶剂和去污剂的转染活性囊泡的组合物和系统以及与之相关的方法 |
| CN111072504A (zh) * | 2019-12-31 | 2020-04-28 | 芜湖天道绿色新材料有限公司 | 一种可降解固化剂的一步制备方法 |
| CN114522252B (zh) * | 2022-04-24 | 2023-08-04 | 天津外泌体科技有限公司 | 一步法叠氮化修饰细胞外囊泡的方法及修饰试剂 |
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| CN120659770A (zh) * | 2023-03-22 | 2025-09-16 | 上海环码生物医药有限公司 | 脂质化合物、脂质纳米颗粒和药物组合物 |
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| JP2015007021A (ja) * | 2013-06-26 | 2015-01-15 | 富士フイルム株式会社 | 脂質粒子、核酸送達キャリア、核酸送達キャリア製造用組成物、脂質粒子の製造方法及び遺伝子導入方法 |
| WO2016121942A1 (ja) * | 2015-01-30 | 2016-08-04 | 日油株式会社 | カチオン性脂質 |
| JP2022516318A (ja) * | 2019-01-04 | 2022-02-25 | オンコラス， インコーポレイテッド | カプセル化ポリヌクレオチド及び使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010057155A1 (en) | 2010-05-20 |
| EP2364085A1 (en) | 2011-09-14 |
| US20110229581A1 (en) | 2011-09-22 |
| TW201021853A (en) | 2010-06-16 |
| EP2364085A4 (en) | 2012-12-12 |
| CN102231952A (zh) | 2011-11-02 |
| CA2742776A1 (en) | 2010-05-20 |
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