JP2012509272A5 - - Google Patents

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Publication number
JP2012509272A5
JP2012509272A5 JP2011536583A JP2011536583A JP2012509272A5 JP 2012509272 A5 JP2012509272 A5 JP 2012509272A5 JP 2011536583 A JP2011536583 A JP 2011536583A JP 2011536583 A JP2011536583 A JP 2011536583A JP 2012509272 A5 JP2012509272 A5 JP 2012509272A5
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Japan
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JP2011536583A
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JP2012509272A (ja
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Priority claimed from PCT/US2009/064719 external-priority patent/WO2010057155A1/en
Publication of JP2012509272A publication Critical patent/JP2012509272A/ja
Publication of JP2012509272A5 publication Critical patent/JP2012509272A5/ja
Pending legal-status Critical Current

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JP2011536583A 2008-11-17 2009-11-17 核酸送達系のための放出性カチオン脂質 Pending JP2012509272A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US11536508P 2008-11-17 2008-11-17
US11534808P 2008-11-17 2008-11-17
US11528708P 2008-11-17 2008-11-17
US61/115,365 2008-11-17
US61/115,287 2008-11-17
US61/115,348 2008-11-17
PCT/US2009/064719 WO2010057155A1 (en) 2008-11-17 2009-11-17 Releasable cationic lipids for nucleic acids delivery systems

Publications (2)

Publication Number Publication Date
JP2012509272A JP2012509272A (ja) 2012-04-19
JP2012509272A5 true JP2012509272A5 (enExample) 2012-12-27

Family

ID=42170406

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011536583A Pending JP2012509272A (ja) 2008-11-17 2009-11-17 核酸送達系のための放出性カチオン脂質

Country Status (7)

Country Link
US (1) US20110229581A1 (enExample)
EP (1) EP2364085A4 (enExample)
JP (1) JP2012509272A (enExample)
CN (1) CN102231952A (enExample)
CA (1) CA2742776A1 (enExample)
TW (1) TW201021853A (enExample)
WO (1) WO2010057155A1 (enExample)

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CN101870719B (zh) * 2010-05-21 2013-09-25 中国科学院上海有机化学研究所 一种同时具有二硫化学键和甾体骨架结构的有机功能化合物、制备方法和用途
CN102161688B (zh) * 2011-02-18 2013-09-04 中国科学院上海有机化学研究所 一种含有胆固醇结构片段的生物相容性合成脂质体、制备方法及其应用
US10184151B2 (en) 2011-10-11 2019-01-22 The Brigham And Women's Hospital, Inc. Micrornas in neurodegenerative disorders
EP3485875A1 (en) * 2011-11-04 2019-05-22 Nitto Denko Corporation Single use system for sterelily producing lipid-nucleic acid particles
US9579338B2 (en) 2011-11-04 2017-02-28 Nitto Denko Corporation Method of producing lipid nanoparticles for drug delivery
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CN102911252B (zh) * 2012-10-25 2014-07-16 四川大学 含肽类树状分子的阳离子脂质、转基因载体及其制备方法和应用
WO2014089239A1 (en) * 2012-12-07 2014-06-12 Alnylam Pharmaceuticals, Inc. Improved nucleic acid lipid particle formulations
WO2014178152A1 (ja) 2013-04-30 2014-11-06 Ｄｅｌｔａ－Ｆｌｙ Ｐｈａｒｍａ株式会社 局所投与用リポソームおよびその用途
JP5914418B2 (ja) * 2013-06-26 2016-05-11 富士フイルム株式会社 脂質粒子、核酸送達キャリア、核酸送達キャリア製造用組成物、脂質粒子の製造方法及び遺伝子導入方法
WO2015021465A2 (en) * 2013-08-09 2015-02-12 New York University Protein engineered systems for delivery of molecules
WO2015178438A1 (ja) * 2014-05-20 2015-11-26 アルケア株式会社 皮膚用粘着剤組成物及び皮膚用貼付材
AU2015337909B2 (en) 2014-10-30 2018-12-13 Delta-Fly Pharma, Inc. New production method of lipoplex for local administration and antitumor drug using lipoplex
CA2975371C (en) * 2015-01-30 2024-02-13 Nof Corporation Cationic lipid for nucleic acid delivery
US11459568B2 (en) 2016-10-31 2022-10-04 University Of Massachusetts Targeting microRNA-101-3p in cancer therapy
EP3315125A1 (en) * 2016-10-31 2018-05-02 Silence Therapeutics (London) Ltd Lipid nanoparticle formulation
CN106565763B (zh) * 2016-11-11 2017-12-15 深圳市声光动力生物医药科技有限公司 pH敏感的轴向取代硅酞菁配合物及其制备方法和在医药上的应用
HRP20240586T1 (hr) 2018-10-09 2024-07-19 The University Of British Columbia Sastavi i sustavi koji sadrže transfekcijske sposobne vezikle bez organskih otapala i deterdženta i s njim povezanim postupcima
JP2022516318A (ja) * 2019-01-04 2022-02-25 オンコラス， インコーポレイテッド カプセル化ポリヌクレオチド及び使用方法
CN111072504A (zh) * 2019-12-31 2020-04-28 芜湖天道绿色新材料有限公司 一种可降解固化剂的一步制备方法
CN114522252B (zh) * 2022-04-24 2023-08-04 天津外泌体科技有限公司 一步法叠氮化修饰细胞外囊泡的方法及修饰试剂
CN114984236B (zh) * 2022-04-29 2023-03-24 深圳近邻生物科技有限公司 一种响应型核酸递送系统及其制备方法、交联聚合物载体
EP4683906A1 (en) * 2023-03-22 2026-01-28 Shanghai Circode Biomed Co., Ltd Lipid compounds, lipid nanoparticles, and pharmaceutical compositions
CN121443317A (zh) * 2023-03-27 2026-01-30 英特纳疗法有限公司 肽跨膜递送系统及其用途
CN120227354A (zh) * 2023-12-29 2025-07-01 康希诺(上海)生物研发有限公司 一种用于递送核酸的脂质纳米颗粒及其制备方法和用途

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TW201021852A (en) * 2008-11-17 2010-06-16 Enzon Pharmaceuticals Inc Releasable fusogenic lipids for nucleic acids delivery systems

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