JP2012509264A5 - - Google Patents
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- Publication number
- JP2012509264A5 JP2012509264A5 JP2011536397A JP2011536397A JP2012509264A5 JP 2012509264 A5 JP2012509264 A5 JP 2012509264A5 JP 2011536397 A JP2011536397 A JP 2011536397A JP 2011536397 A JP2011536397 A JP 2011536397A JP 2012509264 A5 JP2012509264 A5 JP 2012509264A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- lactide
- weight
- ester
- poly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001244 Poly(D,L-lactide) Polymers 0.000 claims 24
- 229920000642 polymer Polymers 0.000 claims 24
- 239000007943 implant Substances 0.000 claims 20
- XYLJNLCSTIOKRM-UHFFFAOYSA-N Alphagan Chemical group C1=CC2=NC=CN=C2C(Br)=C1NC1=NCCN1 XYLJNLCSTIOKRM-UHFFFAOYSA-N 0.000 claims 10
- 229960003679 brimonidine Drugs 0.000 claims 10
- 150000002148 esters Chemical class 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 7
- 229920002988 biodegradable polymer Polymers 0.000 claims 6
- 239000004621 biodegradable polymer Substances 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 6
- 229920003178 (lactide-co-glycolide) polymer Polymers 0.000 claims 4
- IWEGDQUCWQFKHS-UHFFFAOYSA-N 1-(1,3-dioxolan-2-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole Chemical compound O1C(C)(C)C(C)(C)OB1C1=CN(CC2OCCO2)N=C1 IWEGDQUCWQFKHS-UHFFFAOYSA-N 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 4
- 229960001724 brimonidine tartrate Drugs 0.000 claims 4
- 239000000384 adrenergic alpha-2 receptor agonist Substances 0.000 claims 3
- 208000010412 Glaucoma Diseases 0.000 claims 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/272,548 | 2008-11-17 | ||
| US12/272,548 US9095506B2 (en) | 2008-11-17 | 2008-11-17 | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
| PCT/US2009/063490 WO2010056598A2 (en) | 2008-11-17 | 2009-11-06 | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014143227A Division JP2014184348A (ja) | 2008-11-17 | 2014-07-11 | 生分解性α−２アゴニストポリマー性インプラントおよびその治療用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012509264A JP2012509264A (ja) | 2012-04-19 |
| JP2012509264A5 true JP2012509264A5 (enExample) | 2012-12-20 |
| JP5580832B2 JP5580832B2 (ja) | 2014-08-27 |
Family
ID=41698087
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536397A Expired - Fee Related JP5580832B2 (ja) | 2008-11-17 | 2009-11-06 | 生分解性α−２アゴニストポリマー性インプラントおよびその治療用途 |
| JP2014143227A Pending JP2014184348A (ja) | 2008-11-17 | 2014-07-11 | 生分解性α−２アゴニストポリマー性インプラントおよびその治療用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014143227A Pending JP2014184348A (ja) | 2008-11-17 | 2014-07-11 | 生分解性α−２アゴニストポリマー性インプラントおよびその治療用途 |
Country Status (7)
| Country | Link |
|---|---|
| US (7) | US9095506B2 (enExample) |
| EP (1) | EP2355795B1 (enExample) |
| JP (2) | JP5580832B2 (enExample) |
| AU (3) | AU2009314266A1 (enExample) |
| CA (1) | CA2743837C (enExample) |
| ES (1) | ES2624448T3 (enExample) |
| WO (1) | WO2010056598A2 (enExample) |
Families Citing this family (59)
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| US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
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| US9498457B2 (en) | 2004-04-30 | 2016-11-22 | Allergan, Inc. | Hypotensive prostamide-containing biodegradable intraocular implants and related implants |
| US8969415B2 (en) | 2006-12-01 | 2015-03-03 | Allergan, Inc. | Intraocular drug delivery systems |
| US20100104654A1 (en) | 2008-10-27 | 2010-04-29 | Allergan, Inc. | Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof |
| US9095506B2 (en) | 2008-11-17 | 2015-08-04 | Allergan, Inc. | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
| EP2432420A4 (en) | 2009-05-18 | 2018-01-10 | Dose Medical Corporation | Drug eluting ocular implant |
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| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| EP2437684B1 (en) | 2009-06-03 | 2022-06-15 | ForSight Vision5, Inc. | Anterior segment drug delivery |
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| US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
| JP5989780B2 (ja) | 2011-09-14 | 2016-09-07 | フォーサイト・ビジョン５・インコーポレイテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ５，Ｉｎｃ． | 眼挿入装置および方法 |
| US8962577B2 (en) | 2012-03-16 | 2015-02-24 | The Johns Hopkins University | Controlled release formulations for the delivery of HIF-1 inhibitors |
| JP6138904B2 (ja) * | 2012-03-16 | 2017-05-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 活性剤の送達のための非線状マルチブロックコポリマー薬物コンジュゲート |
| RU2652063C2 (ru) | 2012-10-26 | 2018-04-24 | Форсайт Вижн5, Инк. | Офтальмологическая система для замедленного высвобождения лекарственного средства в глазу |
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| AU2015266850B2 (en) | 2014-05-29 | 2019-12-05 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| EP3179982B1 (en) | 2014-07-28 | 2023-07-19 | Sun Pharma Advanced Research Company Ltd | Method of increasing bioavailability and/or prolonging ophthalmic action of a drug |
| CA2957764C (en) | 2014-08-13 | 2019-07-02 | The Johns Hopkins University | Glucocorticoid-loaded nanoparticles for prevention of corneal allograft rejection and neovascularization |
| JP6847848B2 (ja) | 2014-12-15 | 2021-03-24 | ザ ジョーンズ ホプキンズ ユニバーシティＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ | スニチニブ製剤、及び緑内障の治療におけるその使用方法 |
| US20180008718A1 (en) | 2015-01-20 | 2018-01-11 | The Johns Hopkins University | Compositions for the sustained release of anti-glaucoma agents to control intraocular pressure |
| JP6827617B2 (ja) | 2015-03-06 | 2021-02-10 | アエリー ファーマシューティカルズ インコーポレイテッド | 医療移植片送達の装置 |
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| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| US20160296532A1 (en) | 2015-04-13 | 2016-10-13 | Forsight Vision5, Inc. | Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent |
| CN108883070A (zh) | 2015-07-23 | 2018-11-23 | 爱瑞制药公司 | 用于治疗眼病的玻璃体内药物递送系统 |
| JP6856620B2 (ja) * | 2015-07-27 | 2021-04-07 | サン、ファーマ、アドバンスト、リサーチ、カンパニー、リミテッドＳｕｎ Ｐｈａｒｍａ Ａｄｖａｎｃｅｄ Ｒｅｓｅａｒｃｈ Ｃｏｍｐａｎｙ Ｌｉｍｉｔｅｄ | 薬剤搭載ナノ樹脂粒子 |
| WO2017040853A1 (en) | 2015-09-02 | 2017-03-09 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
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| HK1257499A1 (zh) | 2015-11-12 | 2019-10-25 | Graybug Vision, Inc. | 用於治疗的聚集性微粒 |
| US9579350B1 (en) | 2016-02-25 | 2017-02-28 | MAM Holdings of West Florida, L.L.C. | Human amniotic fluid preparation having long-term stability |
| WO2017151879A1 (en) | 2016-03-02 | 2017-09-08 | The Johns Hopkins University | Compositions for sustained release of anti-glaucoma agents to control intraocular pressure |
| AU2017252294B2 (en) | 2016-04-20 | 2021-12-02 | Glaukos Corporation | Bioresorbable ocular drug delivery device |
| AU2017321980B2 (en) | 2016-09-02 | 2020-04-30 | Alcon Inc. | Implant applicators |
| EP3600324A4 (en) | 2017-03-23 | 2020-12-09 | Graybug Vision, Inc. | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS |
| AU2018265415A1 (en) | 2017-05-10 | 2019-10-31 | Graybug Vision, Inc. | Extended release microparticles and suspensions thereof for medical therapy |
| WO2019071245A1 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | IMPLANTABLE DEPOSITS FOR REGULATED RELEASE OF ANALGESICS TO TREAT POSTHOPERATIVE PAIN ASSOCIATED WITH ORTHOPEDIC SURGERY, AND RELATED DEVICES, SYSTEMS, AND METHODS |
| CN116650732A (zh) | 2018-01-08 | 2023-08-29 | 铸造疗法股份有限公司 | 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法 |
| US12458589B2 (en) | 2018-05-12 | 2025-11-04 | Foundry Therapeutics, Inc. | Implantable polymer depots for the controlled release of therapeutic agents |
| MX2020014160A (es) * | 2018-06-25 | 2021-03-09 | Titan Pharmaceuticals Inc | Implantes para liberacion de sustancias farmaceuticas lipofilicas o anfifilicas. |
| WO2020047013A1 (en) | 2018-08-28 | 2020-03-05 | Foundry Therapeutics, Inc. | Polymer implants |
| KR20210135560A (ko) * | 2019-03-05 | 2021-11-15 | 에어리 파마슈티컬즈, 인코포레이티드 | 안구 질환 또는 장애를 치료하는 약학 조성물 |
| TW202216159A (zh) | 2020-07-21 | 2022-05-01 | 美商歐樂根公司 | 具高負載前列腺素醯胺之眼內植入物 |
| CA3267932A1 (en) | 2022-10-05 | 2024-04-11 | Mireca Medicines Gmbh | MICROPARCEL AND IMPLANT FORMULATIONS FOR ANALOGUE CGMP THERAPY |
| WO2025179071A1 (en) * | 2024-02-20 | 2025-08-28 | Bausch + Lomb Ireland Limited | Sustained-release drug delivery compositions for treating ocular diseases |
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-
2008
- 2008-11-17 US US12/272,548 patent/US9095506B2/en active Active
-
2009
- 2009-11-06 ES ES09799446.1T patent/ES2624448T3/es active Active
- 2009-11-06 WO PCT/US2009/063490 patent/WO2010056598A2/en not_active Ceased
- 2009-11-06 CA CA2743837A patent/CA2743837C/en active Active
- 2009-11-06 JP JP2011536397A patent/JP5580832B2/ja not_active Expired - Fee Related
- 2009-11-06 EP EP09799446.1A patent/EP2355795B1/en not_active Not-in-force
- 2009-11-06 AU AU2009314266A patent/AU2009314266A1/en not_active Abandoned
-
2014
- 2014-07-11 JP JP2014143227A patent/JP2014184348A/ja active Pending
-
2015
- 2015-08-03 US US14/816,401 patent/US9522113B2/en not_active Expired - Fee Related
-
2016
- 2016-07-01 AU AU2016204582A patent/AU2016204582A1/en not_active Abandoned
- 2016-12-19 US US15/383,079 patent/US9861576B2/en not_active Expired - Fee Related
-
2018
- 2018-01-08 US US15/864,990 patent/US10471004B2/en active Active
- 2018-04-12 AU AU2018202557A patent/AU2018202557B2/en not_active Ceased
-
2019
- 2019-11-11 US US16/679,737 patent/US10842739B2/en not_active Expired - Fee Related
-
2020
- 2020-11-06 US US17/091,434 patent/US20210161809A1/en not_active Abandoned
-
2022
- 2022-07-15 US US17/812,893 patent/US20230285279A1/en not_active Abandoned
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