JP2019512006A5 - - Google Patents

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Publication number
JP2019512006A5
JP2019512006A5 JP2018541254A JP2018541254A JP2019512006A5 JP 2019512006 A5 JP2019512006 A5 JP 2019512006A5 JP 2018541254 A JP2018541254 A JP 2018541254A JP 2018541254 A JP2018541254 A JP 2018541254A JP 2019512006 A5 JP2019512006 A5 JP 2019512006A5
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JP
Japan
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peg
pla
poly
dbco
conh2
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JP2018541254A
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English (en)
Japanese (ja)
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JP2019512006A (ja
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Priority claimed from PCT/US2016/047807 external-priority patent/WO2017138983A1/en
Publication of JP2019512006A publication Critical patent/JP2019512006A/ja
Publication of JP2019512006A5 publication Critical patent/JP2019512006A5/ja
Pending legal-status Critical Current

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JP2018541254A 2016-02-10 2016-08-19 Egfrリガンドを有する治療用ナノ粒子ならびにその作製および使用方法 Pending JP2019512006A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662293609P 2016-02-10 2016-02-10
US62/293,609 2016-02-10
US201662369590P 2016-08-01 2016-08-01
US62/369,590 2016-08-01
PCT/US2016/047807 WO2017138983A1 (en) 2016-02-10 2016-08-19 Therapeutic nanoparticles having egfr ligands and methods of making and using same

Publications (2)

Publication Number Publication Date
JP2019512006A JP2019512006A (ja) 2019-05-09
JP2019512006A5 true JP2019512006A5 (enExample) 2019-09-19

Family

ID=59496509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018541254A Pending JP2019512006A (ja) 2016-02-10 2016-08-19 Egfrリガンドを有する治療用ナノ粒子ならびにその作製および使用方法

Country Status (7)

Country Link
US (2) US10137088B2 (enExample)
EP (1) EP3413917A4 (enExample)
JP (1) JP2019512006A (enExample)
CN (1) CN108697815A (enExample)
AU (1) AU2016392719A1 (enExample)
CA (1) CA3013896A1 (enExample)
WO (1) WO2017138983A1 (enExample)

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US9987354B2 (en) 2011-04-29 2018-06-05 Selecta Biosciences, Inc. Tolerogenic synthetic nanocarriers for antigen-specific deletion of T effector cells
CN110251675A (zh) 2013-05-03 2019-09-20 西莱克塔生物科技公司 降低或预防响应于非变应原性抗原的过敏反应的致耐受性合成纳米载体
WO2016037161A2 (en) 2014-09-07 2016-03-10 Selecta Biosciences, Inc. Methods and compositions for attenuating gene editing anti-viral transfer vector immune responses
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
DK3562503T3 (da) 2016-12-30 2025-05-26 Vaxcyte Inc Polypeptid-antigen-konjugater med ikke-naturlige aminosyrer
ES3036482T3 (en) 2017-03-11 2025-09-19 Cartesian Therapeutics Inc Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant
CN109966780B (zh) * 2019-03-21 2021-03-09 浙江工商大学 一种水生贝类蒸煮汤中功能性纳米颗粒的分离方法
AU2020287627A1 (en) 2019-06-04 2021-11-18 Selecta Biosciences, Inc. Formulations and doses of PEGylated uricase
AU2021236234A1 (en) * 2020-03-11 2022-10-06 Selecta Biosciences, Inc. Methods and compositions related to synthetic nanocarriers
US20230310647A1 (en) * 2020-08-19 2023-10-05 The Trustees Of The University Of Pennsylvania Targeting cartilage egfr pathway for osteoarthritis treatment
CN114133432B (zh) * 2021-11-01 2023-06-16 暨南大学 一种抑制肿瘤细胞生长和转移的靶向肽及其应用
WO2023079677A1 (ja) * 2021-11-05 2023-05-11 日本電信電話株式会社 分子拡散評価方法およびシステム
CA3237153A1 (en) 2021-11-05 2023-05-11 Targimmune Therapeutics Ag Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same
CN114813998B (zh) * 2022-03-24 2023-05-23 天津键凯科技有限公司 一种聚合物的检测方法
CN115006390B (zh) * 2022-06-27 2024-04-19 国药集团动物保健股份有限公司 一种病毒减毒制剂、其制备方法以及应用
CN115317515B (zh) * 2022-07-19 2024-08-20 沈阳药科大学 氯尼达明/牛血清白蛋白/磷酸铁多效协同仿生矿化纳米制剂及制备方法和应用
AU2023376546A1 (en) 2022-11-07 2025-05-15 Targimmune Therapeutics Ag Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same
IL320618A (en) 2022-11-07 2025-07-01 Targimmune Therapeutics Ag Polyplexes of nucleic acids and targeted pairs containing polyethyleneimine and polyethylene glycol
WO2025238236A1 (en) 2024-05-16 2025-11-20 Targimmune Therapeutics Ag Polyplexes of nucleic acids and targeted conjugates comprising polyethyleneimine and polyethylene glycol
CN119280422B (zh) * 2024-10-09 2025-09-26 浙江大学 一种生物相容的双靶向药物递送二聚体纳米颗粒的制备方法

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US8278415B2 (en) * 2006-12-21 2012-10-02 Centocor, Inc. Dimeric high affinity EGFR constructs and uses thereof
WO2008079982A2 (en) * 2006-12-21 2008-07-03 Centocor, Inc. Liposome composition for targeting egfr receptor
KR20100128291A (ko) 2008-02-14 2010-12-07 브리스톨-마이어스 스큅 컴퍼니 Egfr에 결합하는 조작된 단백질을 기초로 하는 표적화된 치료제
CN102099016A (zh) * 2008-06-16 2011-06-15 佰恩德生物科学股份有限公司 载药的聚合物纳米微粒及其制备和使用方法
EA020753B1 (ru) * 2008-06-16 2015-01-30 Бинд Терапьютикс, Инк. Терапевтические полимерные наночастицы, содержащие алкалоиды vinca, и их применение
ES2765240T3 (es) * 2008-06-16 2020-06-08 Pfizer Nanopartículas poliméricas cargadas de fármaco y procedimientos de fabricación y uso de las mismas
US20120052041A1 (en) * 2009-02-04 2012-03-01 The Brigham And Women's Hospital, Inc. Polymeric nanoparticles with enhanced drug-loading and methods of use thereof
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US20140308363A1 (en) * 2011-05-31 2014-10-16 Bind Therapeutics, Inc. Drug loaded polymeric nanoparticles and methods of making and using same
CA2878059A1 (en) * 2012-07-31 2014-02-06 The University Of Akron Polymeric structures containing strained cycloalkyne functionality for post-fabrication azidealkyne cycloaddition functionalization
CN104045699A (zh) * 2013-03-15 2014-09-17 深圳君圣泰生物技术有限公司 一种多肽、多肽衍生物、多肽的可药用盐及药物组合物
WO2014139182A1 (en) * 2013-03-15 2014-09-18 Shenzhen Hightide Biopharmaceutical, Ltd. Compositions and methods of using islet neogenesis peptides and analogs thereof
WO2015157213A1 (en) * 2014-04-08 2015-10-15 California Institute Of Technology Egfr-targeted nanoparticles
CN103893124B (zh) * 2014-04-24 2016-08-24 中国药科大学 基于协同组装的基因治疗药物递送系统

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