JP2019512006A5 - - Google Patents
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- JP2019512006A5 JP2019512006A5 JP2018541254A JP2018541254A JP2019512006A5 JP 2019512006 A5 JP2019512006 A5 JP 2019512006A5 JP 2018541254 A JP2018541254 A JP 2018541254A JP 2018541254 A JP2018541254 A JP 2018541254A JP 2019512006 A5 JP2019512006 A5 JP 2019512006A5
- Authority
- JP
- Japan
- Prior art keywords
- peg
- pla
- poly
- dbco
- conh2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662293609P | 2016-02-10 | 2016-02-10 | |
| US62/293,609 | 2016-02-10 | ||
| US201662369590P | 2016-08-01 | 2016-08-01 | |
| US62/369,590 | 2016-08-01 | ||
| PCT/US2016/047807 WO2017138983A1 (en) | 2016-02-10 | 2016-08-19 | Therapeutic nanoparticles having egfr ligands and methods of making and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019512006A JP2019512006A (ja) | 2019-05-09 |
| JP2019512006A5 true JP2019512006A5 (enExample) | 2019-09-19 |
Family
ID=59496509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018541254A Pending JP2019512006A (ja) | 2016-02-10 | 2016-08-19 | Ｅｇｆｒリガンドを有する治療用ナノ粒子ならびにその作製および使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10137088B2 (enExample) |
| EP (1) | EP3413917A4 (enExample) |
| JP (1) | JP2019512006A (enExample) |
| CN (1) | CN108697815A (enExample) |
| AU (1) | AU2016392719A1 (enExample) |
| CA (1) | CA3013896A1 (enExample) |
| WO (1) | WO2017138983A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107320734A (zh) | 2011-04-29 | 2017-11-07 | 西莱克塔生物科技公司 | 从合成纳米载体中控制释放免疫抑制剂 |
| CN105307641A (zh) | 2013-05-03 | 2016-02-03 | 西莱克塔生物科技公司 | 用于降低不期望体液免疫应答的给药组合 |
| EA201790551A1 (ru) | 2014-09-07 | 2017-07-31 | Селекта Байосайенсиз, Инк. | Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| IL267709B2 (en) | 2016-12-30 | 2025-04-01 | Vaxcyte Inc | Polypeptide-antigen conjugates with unnatural amino acids |
| EP4599848A3 (en) | 2017-03-11 | 2025-12-03 | Cartesian Therapeutics, Inc. | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| CN109966780B (zh) * | 2019-03-21 | 2021-03-09 | 浙江工商大学 | 一种水生贝类蒸煮汤中功能性纳米颗粒的分离方法 |
| US12553041B2 (en) | 2019-06-04 | 2026-02-17 | Cartesian Therapeutics Inc. | Formulations and doses of pegylated uricase |
| CA3174988A1 (en) * | 2020-03-11 | 2021-09-16 | Selecta Biosciences, Inc. | Methods and compositions related to synthetic nanocarriers |
| WO2022040006A1 (en) * | 2020-08-19 | 2022-02-24 | The Trustees Of The University Of Pennsylvania | Targeting cartilage egfr pathway for osteoarthritis treatment |
| CN114133432B (zh) * | 2021-11-01 | 2023-06-16 | 暨南大学 | 一种抑制肿瘤细胞生长和转移的靶向肽及其应用 |
| WO2023079142A2 (en) | 2021-11-05 | 2023-05-11 | Targimmune Therapeutics Ag | Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same |
| WO2023079677A1 (ja) * | 2021-11-05 | 2023-05-11 | 日本電信電話株式会社 | 分子拡散評価方法およびシステム |
| CN114813998B (zh) * | 2022-03-24 | 2023-05-23 | 天津键凯科技有限公司 | 一种聚合物的检测方法 |
| CN115006390B (zh) * | 2022-06-27 | 2024-04-19 | 国药集团动物保健股份有限公司 | 一种病毒减毒制剂、其制备方法以及应用 |
| CN115317515B (zh) * | 2022-07-19 | 2024-08-20 | 沈阳药科大学 | 氯尼达明/牛血清白蛋白/磷酸铁多效协同仿生矿化纳米制剂及制备方法和应用 |
| JP2025540912A (ja) | 2022-11-07 | 2025-12-17 | ターグイミューン セラピューティクス アクチエンゲゼルシャフト | ポリエチレンイミン及びポリエチレングリコールを含む標的化された線状コンジュゲート並びにそれを含むポリプレックス |
| IL320618A (en) | 2022-11-07 | 2025-07-01 | Targimmune Therapeutics Ag | Polyplexes of nucleic acids and targeted pairs containing polyethyleneimine and polyethylene glycol |
| WO2025238236A1 (en) | 2024-05-16 | 2025-11-20 | Targimmune Therapeutics Ag | Polyplexes of nucleic acids and targeted conjugates comprising polyethyleneimine and polyethylene glycol |
| CN119280422B (zh) * | 2024-10-09 | 2025-09-26 | 浙江大学 | 一种生物相容的双靶向药物递送二聚体纳米颗粒的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8278415B2 (en) * | 2006-12-21 | 2012-10-02 | Centocor, Inc. | Dimeric high affinity EGFR constructs and uses thereof |
| WO2008079982A2 (en) * | 2006-12-21 | 2008-07-03 | Centocor, Inc. | Liposome composition for targeting egfr receptor |
| EP2247615B1 (en) * | 2008-02-14 | 2014-07-30 | Bristol-Myers Squibb Company | Targeted therapeutics based on engineered proteins that bind egfr |
| EA020753B1 (ru) * | 2008-06-16 | 2015-01-30 | Бинд Терапьютикс, Инк. | Терапевтические полимерные наночастицы, содержащие алкалоиды vinca, и их применение |
| AU2009268923B2 (en) * | 2008-06-16 | 2015-09-17 | Pfizer Inc. | Drug loaded polymeric nanoparticles and methods of making and using same |
| CN102099016A (zh) * | 2008-06-16 | 2011-06-15 | 佰恩德生物科学股份有限公司 | 载药的聚合物纳米微粒及其制备和使用方法 |
| WO2010091187A2 (en) * | 2009-02-04 | 2010-08-12 | The Brigham And Women's Hospital, Inc. | Polymeric nanoparticles with enhanced drug-loading and methods of use thereof |
| JP5927194B2 (ja) * | 2010-09-24 | 2016-06-01 | マリンクロッド エルエルシー | 治療ナノキャリアおよび／または診断ナノキャリアのターゲティングのためのアプタマーコンジュゲート |
| US20140308363A1 (en) * | 2011-05-31 | 2014-10-16 | Bind Therapeutics, Inc. | Drug loaded polymeric nanoparticles and methods of making and using same |
| WO2014022535A1 (en) * | 2012-07-31 | 2014-02-06 | The University Of Akron | Polymeric structures containing strained cycloalkyne functionality for post-fabrication azidealkyne cycloaddition functionalization |
| US20160039877A1 (en) * | 2013-03-15 | 2016-02-11 | Shenzhen Hightide Biopharmaceutical, Ltd. | Compositions and methods of using islet neogenesis peptides and analogs thereof |
| EP3129061A1 (en) * | 2014-04-08 | 2017-02-15 | California Institute of Technology | Egfr-targeted nanoparticles |
| CN103893124B (zh) * | 2014-04-24 | 2016-08-24 | 中国药科大学 | 基于协同组装的基因治疗药物递送系统 |
-
2016
- 2016-08-19 AU AU2016392719A patent/AU2016392719A1/en not_active Abandoned
- 2016-08-19 CA CA3013896A patent/CA3013896A1/en not_active Abandoned
- 2016-08-19 US US15/241,977 patent/US10137088B2/en not_active Expired - Fee Related
- 2016-08-19 CN CN201680081577.7A patent/CN108697815A/zh active Pending
- 2016-08-19 EP EP16890090.0A patent/EP3413917A4/en not_active Withdrawn
- 2016-08-19 JP JP2018541254A patent/JP2019512006A/ja active Pending
- 2016-08-19 WO PCT/US2016/047807 patent/WO2017138983A1/en not_active Ceased
-
2018
- 2018-10-12 US US16/158,467 patent/US20190029960A1/en not_active Abandoned
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