ES2624448T3 - Implantes poliméricos de agonistas alfa-2 adrenérgicos biodegradables - Google Patents

Implantes poliméricos de agonistas alfa-2 adrenérgicos biodegradables Download PDF

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Publication number
ES2624448T3
ES2624448T3 ES09799446.1T ES09799446T ES2624448T3 ES 2624448 T3 ES2624448 T3 ES 2624448T3 ES 09799446 T ES09799446 T ES 09799446T ES 2624448 T3 ES2624448 T3 ES 2624448T3
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ES
Spain
Prior art keywords
implant
polymer
release
implants
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09799446.1T
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English (en)
Spanish (es)
Inventor
Lon T. Spada
Alazar N. Ghebremeskel
Michael R. Robinson
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Allergan Inc
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Allergan Inc
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Publication of ES2624448T3 publication Critical patent/ES2624448T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
ES09799446.1T 2008-11-17 2009-11-06 Implantes poliméricos de agonistas alfa-2 adrenérgicos biodegradables Active ES2624448T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US272548 2002-10-16
US12/272,548 US9095506B2 (en) 2008-11-17 2008-11-17 Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof
PCT/US2009/063490 WO2010056598A2 (en) 2008-11-17 2009-11-06 Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof

Publications (1)

Publication Number Publication Date
ES2624448T3 true ES2624448T3 (es) 2017-07-14

Family

ID=41698087

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09799446.1T Active ES2624448T3 (es) 2008-11-17 2009-11-06 Implantes poliméricos de agonistas alfa-2 adrenérgicos biodegradables

Country Status (7)

Country Link
US (7) US9095506B2 (enExample)
EP (1) EP2355795B1 (enExample)
JP (2) JP5580832B2 (enExample)
AU (3) AU2009314266A1 (enExample)
CA (1) CA2743837C (enExample)
ES (1) ES2624448T3 (enExample)
WO (1) WO2010056598A2 (enExample)

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Also Published As

Publication number Publication date
CA2743837C (en) 2017-03-28
US20200069578A1 (en) 2020-03-05
US9095506B2 (en) 2015-08-04
US20100124565A1 (en) 2010-05-20
AU2018202557B2 (en) 2020-02-27
US10471004B2 (en) 2019-11-12
JP2014184348A (ja) 2014-10-02
JP2012509264A (ja) 2012-04-19
AU2018202557A1 (en) 2018-05-10
US10842739B2 (en) 2020-11-24
EP2355795B1 (en) 2017-01-04
US9522113B2 (en) 2016-12-20
US20160030334A1 (en) 2016-02-04
JP5580832B2 (ja) 2014-08-27
WO2010056598A2 (en) 2010-05-20
US20230285279A1 (en) 2023-09-14
US9861576B2 (en) 2018-01-09
US20210161809A1 (en) 2021-06-03
US20170100334A1 (en) 2017-04-13
AU2009314266A1 (en) 2010-05-20
AU2016204582A1 (en) 2016-07-21
EP2355795A2 (en) 2011-08-17
CA2743837A1 (en) 2010-05-20
WO2010056598A3 (en) 2010-12-23
US20180353426A1 (en) 2018-12-13

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