BR112021017436A2 - Composições farmacêuticas para tratamento de doenças ou transtornos oculares - Google Patents
Composições farmacêuticas para tratamento de doenças ou transtornos ocularesInfo
- Publication number
- BR112021017436A2 BR112021017436A2 BR112021017436A BR112021017436A BR112021017436A2 BR 112021017436 A2 BR112021017436 A2 BR 112021017436A2 BR 112021017436 A BR112021017436 A BR 112021017436A BR 112021017436 A BR112021017436 A BR 112021017436A BR 112021017436 A2 BR112021017436 A2 BR 112021017436A2
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical compositions
- disorders
- ocular diseases
- treating ocular
- released
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 208000022873 Ocular disease Diseases 0.000 title 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000030533 eye disease Diseases 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
composições farmacêuticas para tratamento de doenças ou transtornos oculares. nesta divulgação são fornecidas composições farmacêuticas, implantes intravítreos e suspensões de partículas compreendendo uma matriz de polímero e, pelo menos, um agente terapêutico que é liberado de uma maneira substancialmente linear por um período particular.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962814198P | 2019-03-05 | 2019-03-05 | |
PCT/US2020/021136 WO2020181060A1 (en) | 2019-03-05 | 2020-03-05 | Pharmaceutical compositions for treating ocular diseases or disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112021017436A2 true BR112021017436A2 (pt) | 2021-11-16 |
Family
ID=72337143
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112021017436A BR112021017436A2 (pt) | 2019-03-05 | 2020-03-05 | Composições farmacêuticas para tratamento de doenças ou transtornos oculares |
Country Status (10)
Country | Link |
---|---|
US (1) | US20200306182A1 (pt) |
EP (1) | EP3934646A4 (pt) |
JP (1) | JP2022523548A (pt) |
KR (1) | KR20210135560A (pt) |
CN (1) | CN113784727B (pt) |
AU (1) | AU2020232314C1 (pt) |
BR (1) | BR112021017436A2 (pt) |
CA (1) | CA3132635A1 (pt) |
MX (1) | MX2021010599A (pt) |
WO (1) | WO2020181060A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2952213T3 (es) | 2020-02-06 | 2023-10-30 | Ocular Therapeutix Inc | Composiciones y métodos para tratar enfermedades oculares |
BR112022018815A2 (pt) | 2020-03-25 | 2022-11-29 | Ocular Therapeutix Inc | Implante ocular contendo um inibidor de tirosina cinase |
WO2022232588A1 (en) | 2021-04-30 | 2022-11-03 | Perfuse Therapeutics, Inc. | Pharmaceutical compositions and intravitreal drug delivery systems for the treatment of ocular diseases |
WO2022235906A1 (en) | 2021-05-05 | 2022-11-10 | Aerie Pharmaceuticals, Inc. | Pharmaceutical preparation |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2019645A4 (en) * | 2006-05-02 | 2013-03-06 | Medivas Llc | RELEASE OF OPHTHALMOLOGICAL ACTIVITIES OUTSIDE OR WITHIN THE EYE |
CN102014879A (zh) * | 2008-04-25 | 2011-04-13 | 帝斯曼知识产权资产管理有限公司 | 含有具有硫酯键的聚合物的颗粒 |
KR101699497B1 (ko) * | 2010-06-22 | 2017-01-24 | 도요보 가부시키가이샤 | 액정표시장치, 편광판 및 편광자 보호 필름 |
WO2012150255A1 (en) * | 2011-05-02 | 2012-11-08 | Dsm Ip Assets B.V. | Bis-(alpha-amino-diol-diester) containing polyesteramide for ophtamology |
US20140179802A1 (en) * | 2011-05-02 | 2014-06-26 | Dsm Ip Assets B.V. | Fiber comprising a biodegradable polymer |
US9789189B2 (en) * | 2012-10-02 | 2017-10-17 | Dsm Ip Assets Bv | Drug delivery composition comprising proteins and biodegradable polyesteramides |
RU2015146211A (ru) * | 2013-04-01 | 2017-05-19 | Аллерган, Инк. | Микросферная система доставки лекарственного средства для замедленного внутриглазного высвобождения |
CN105431135A (zh) * | 2013-11-08 | 2016-03-23 | 泰尔克斯公司 | 用于治疗手术并发症的聚合给药系统 |
US20160296627A1 (en) * | 2013-12-06 | 2016-10-13 | Envisia Therapeutics Inc. | Intracameral implant for treatment of an ocular condition |
EP3082761A2 (en) * | 2013-12-20 | 2016-10-26 | Emory University | Formulations and methods for targeted ocular delivery of therapeutic agents |
JP7026507B2 (ja) * | 2014-09-06 | 2022-02-28 | インテグラル バイオシステムズ エルエルシー | 眼において薬物徐放を達成する方法及び生体適合性組成物 |
WO2016097297A1 (en) * | 2014-12-18 | 2016-06-23 | Dsm Ip Assets B.V. | Drug delivery system for delivery of acid sensitive drugs |
EP3324944A4 (en) * | 2015-07-23 | 2019-04-03 | Aerie Pharmaceuticals, Inc. | INTRAVITREAL AGGREGATION SYSTEMS FOR THE TREATMENT OF EYE DISEASE |
WO2017120600A1 (en) * | 2016-01-08 | 2017-07-13 | Clearside Biomedical, Inc. | Compositions and methods of treating wet age-related macular degeneration |
US20180117148A1 (en) * | 2016-10-28 | 2018-05-03 | Andrew J. Holman | Compounds, pharmaceutical compositions and methods of treatments of immune related diseases and disorders |
EP3570888A1 (en) * | 2017-03-03 | 2019-11-27 | MacRegen, Inc. | Treatment of age-related macular degeneration and other eye diseases with one or more therapeutic agents |
-
2020
- 2020-03-05 US US16/810,149 patent/US20200306182A1/en active Pending
- 2020-03-05 EP EP20766052.3A patent/EP3934646A4/en active Pending
- 2020-03-05 MX MX2021010599A patent/MX2021010599A/es unknown
- 2020-03-05 CN CN202080033265.5A patent/CN113784727B/zh active Active
- 2020-03-05 CA CA3132635A patent/CA3132635A1/en active Pending
- 2020-03-05 AU AU2020232314A patent/AU2020232314C1/en active Active
- 2020-03-05 KR KR1020217031760A patent/KR20210135560A/ko unknown
- 2020-03-05 BR BR112021017436A patent/BR112021017436A2/pt unknown
- 2020-03-05 JP JP2021552571A patent/JP2022523548A/ja active Pending
- 2020-03-05 WO PCT/US2020/021136 patent/WO2020181060A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP3934646A4 (en) | 2022-12-14 |
WO2020181060A1 (en) | 2020-09-10 |
AU2020232314A1 (en) | 2021-09-30 |
AU2020232314B2 (en) | 2023-10-12 |
AU2020232314C1 (en) | 2024-03-28 |
US20200306182A1 (en) | 2020-10-01 |
MX2021010599A (es) | 2021-12-10 |
CA3132635A1 (en) | 2020-09-10 |
CN113784727A (zh) | 2021-12-10 |
KR20210135560A (ko) | 2021-11-15 |
JP2022523548A (ja) | 2022-04-25 |
CN113784727B (zh) | 2024-03-29 |
EP3934646A1 (en) | 2022-01-12 |
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